Motif ID: PGR

Z-value: 0.746


Transcription factors associated with PGR:

Gene SymbolEntrez IDGene Name
PGR ENSG00000082175.10 PGR



Activity profile for motif PGR.

activity profile for motif PGR


Sorted Z-values histogram for motif PGR

Sorted Z-values for motif PGR



Network of associatons between targets according to the STRING database.



First level regulatory network of PGR

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_52105495 0.701 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr1_-_205391178 0.663 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr2_-_183387430 0.629 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387064 0.621 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chrX_+_16964985 0.616 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr2_-_190044480 0.575 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr18_+_32173276 0.569 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr2_+_36923830 0.522 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr2_-_183106641 0.484 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387283 0.459 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr12_-_71551652 0.456 ENST00000546561.1
TSPAN8
tetraspanin 8
chr4_-_90759440 0.442 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr14_-_35182994 0.430 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr6_+_27107053 0.413 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr17_-_26697304 0.408 ENST00000536498.1
VTN
vitronectin
chr17_-_26903900 0.380 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr9_-_107690420 0.377 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr3_-_52001448 0.372 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr3_-_195270162 0.366 ENST00000438848.1
ENST00000328432.3
PPP1R2

protein phosphatase 1, regulatory (inhibitor) subunit 2

chr7_+_130126012 0.345 ENST00000341441.5
MEST
mesoderm specific transcript
chr22_-_31688431 0.335 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr16_+_56970567 0.330 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chrX_+_57618269 0.320 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr12_-_7244469 0.318 ENST00000538050.1
ENST00000536053.2
C1R

complement component 1, r subcomponent

chr8_-_22089845 0.315 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr13_-_52027134 0.314 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr12_+_56473628 0.309 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr15_-_43877062 0.304 ENST00000381885.1
ENST00000396923.3
PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chr5_+_102201509 0.302 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_-_94417339 0.285 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr5_+_102201430 0.285 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr8_-_82644562 0.282 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
ZFAND1


zinc finger, AN1-type domain 1


chr5_-_138718973 0.282 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr11_-_66725837 0.274 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr6_-_32908765 0.272 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_75915757 0.271 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr12_+_56661461 0.270 ENST00000546544.1
ENST00000553234.1
COQ10A

coenzyme Q10 homolog A (S. cerevisiae)

chr17_-_26694979 0.266 ENST00000438614.1
VTN
vitronectin
chr9_+_116225999 0.256 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr11_-_615570 0.255 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7


interferon regulatory factor 7


chr9_-_140196703 0.254 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr7_+_130126165 0.250 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr11_+_7595136 0.245 ENST00000529575.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_57679859 0.240 ENST00000569494.1
ENST00000566169.1
GPR56

G protein-coupled receptor 56

chr1_-_115292591 0.238 ENST00000438362.2
CSDE1
cold shock domain containing E1, RNA-binding
chr13_-_52026730 0.232 ENST00000420668.2
INTS6
integrator complex subunit 6
chr6_-_75828774 0.232 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr11_-_115127611 0.225 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr5_+_102201687 0.223 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr12_-_88974236 0.223 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr22_+_31644388 0.220 ENST00000333611.4
ENST00000340552.4
LIMK2

LIM domain kinase 2

chr8_+_40010989 0.215 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr10_-_16563870 0.213 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr2_+_173686303 0.207 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr18_+_6729725 0.206 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chr5_+_139505520 0.206 ENST00000333305.3
IGIP
IgA-inducing protein
chr10_+_124030819 0.205 ENST00000260723.4
ENST00000368994.2
BTBD16

BTB (POZ) domain containing 16

chr9_-_34665983 0.202 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5



HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015



chr1_+_150229554 0.202 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr5_-_95018660 0.201 ENST00000395899.3
ENST00000274432.8
SPATA9

spermatogenesis associated 9

chr2_-_67442409 0.201 ENST00000414404.1
ENST00000433133.1
AC078941.1

AC078941.1

chr11_-_18343725 0.200 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr5_+_137514403 0.200 ENST00000513276.1
KIF20A
kinesin family member 20A
chr5_+_102201722 0.199 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_-_94417562 0.198 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr13_+_102104980 0.192 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91505608 0.190 ENST00000266718.4
LUM
lumican
chr1_-_145715565 0.188 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160


CD160 molecule


chr11_-_18343669 0.187 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5


Hermansky-Pudlak syndrome 5


chr2_+_27237615 0.186 ENST00000458529.1
ENST00000402218.1
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr11_-_10920714 0.185 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr17_+_22022437 0.185 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chr11_-_10530723 0.178 ENST00000536684.1
MTRNR2L8
MT-RNR2-like 8
chrX_-_21776281 0.177 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr6_+_72926145 0.176 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_110527308 0.175 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr15_+_94899183 0.172 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr19_+_10531150 0.171 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr14_-_64194745 0.170 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr9_+_71394945 0.170 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr16_+_57680840 0.170 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56


G protein-coupled receptor 56


chr6_+_112375462 0.169 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr5_-_79946820 0.168 ENST00000604882.1
MTRNR2L2
MT-RNR2-like 2
chr22_-_41252962 0.163 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr7_+_134576151 0.161 ENST00000393118.2
CALD1
caldesmon 1
chr15_-_49912944 0.160 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr5_-_94417186 0.153 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr12_-_2966193 0.151 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chrX_+_139791917 0.151 ENST00000607004.1
ENST00000370535.3
LINC00632

long intergenic non-protein coding RNA 632

chr19_-_36247910 0.150 ENST00000587965.1
ENST00000004982.3
HSPB6

heat shock protein, alpha-crystallin-related, B6

chr5_-_146435501 0.147 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_-_10920838 0.147 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr18_+_6729698 0.146 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr14_-_67955426 0.145 ENST00000554480.1
TMEM229B
transmembrane protein 229B
chr13_+_102104952 0.145 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr16_+_57679945 0.144 ENST00000568157.1
GPR56
G protein-coupled receptor 56
chr5_+_148442844 0.143 ENST00000515519.1
CTC-529P8.1
CTC-529P8.1
chr5_-_146435572 0.141 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chrX_-_133792480 0.141 ENST00000359237.4
PLAC1
placenta-specific 1
chr5_+_170814803 0.141 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1



nucleophosmin (nucleolar phosphoprotein B23, numatrin)



chr12_+_125478241 0.141 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr1_+_16370271 0.140 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb
chr5_+_133842243 0.140 ENST00000515627.2
AC005355.2
AC005355.2
chr22_+_42017987 0.139 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr8_+_22844995 0.139 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr1_+_162601774 0.138 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr13_+_32838801 0.138 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr15_-_49255632 0.136 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr17_+_46970127 0.136 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_-_54726850 0.136 ENST00000245620.9
ENST00000346401.6
ENST00000424807.1
ENST00000445347.1
LILRB3



leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3



chr2_+_99797542 0.136 ENST00000338148.3
ENST00000512183.2
MRPL30
C2orf15
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr5_-_146435694 0.136 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_+_120255997 0.135 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr4_-_89442940 0.134 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr18_+_21529811 0.134 ENST00000588004.1
LAMA3
laminin, alpha 3
chr9_+_116298778 0.134 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr2_-_179315786 0.134 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA


protein kinase, interferon-inducible double stranded RNA dependent activator


chr19_+_16771936 0.132 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr17_+_46970178 0.132 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr17_-_42466864 0.132 ENST00000353281.4
ENST00000262407.5
ITGA2B

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

chr6_+_30852738 0.131 ENST00000508312.1
ENST00000512336.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr3_+_52454971 0.130 ENST00000465863.1
PHF7
PHD finger protein 7
chr3_-_114343039 0.130 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_117220016 0.129 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr1_+_1846519 0.129 ENST00000378604.3
CALML6
calmodulin-like 6
chr5_-_121413974 0.127 ENST00000231004.4
LOX
lysyl oxidase
chr1_+_155583012 0.125 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr20_+_34129770 0.124 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3






ERGIC and golgi 3






chr2_+_232135245 0.124 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chrX_+_99899180 0.124 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr16_+_57680811 0.120 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr19_-_42947121 0.119 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr14_+_24674926 0.118 ENST00000339917.5
ENST00000556621.1
ENST00000287913.6
ENST00000428351.2
ENST00000555092.1
TSSK4




testis-specific serine kinase 4




chr3_+_44626446 0.118 ENST00000441021.1
ENST00000322734.2
ZNF660

zinc finger protein 660

chr11_+_57105991 0.118 ENST00000263314.2
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
chr19_-_9003586 0.117 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr15_-_58306295 0.117 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_+_65663812 0.117 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1


AC074391.1


chr2_+_27193480 0.117 ENST00000233121.2
ENST00000405074.3
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr17_+_46970134 0.116 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr16_-_3306587 0.115 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV



Mediterranean fever



chr6_-_88299678 0.115 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr1_-_32210275 0.114 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr9_-_15510989 0.114 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1



PC4 and SFRS1 interacting protein 1



chr8_+_118532937 0.112 ENST00000297347.3
MED30
mediator complex subunit 30
chr15_-_42783303 0.110 ENST00000565380.1
ENST00000564754.1
ZNF106

zinc finger protein 106

chr1_+_12524965 0.109 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr17_+_41150793 0.109 ENST00000586277.1
RPL27
ribosomal protein L27
chr2_-_219925189 0.107 ENST00000295731.6
IHH
indian hedgehog
chr7_+_128312346 0.107 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2


family with sequence similarity 71, member F2


chr12_+_118814185 0.106 ENST00000543473.1
SUDS3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr17_+_34136459 0.106 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr11_+_6502675 0.106 ENST00000254616.6
ENST00000530751.1
TIMM10B

translocase of inner mitochondrial membrane 10 homolog B (yeast)

chr7_-_23510086 0.105 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr19_-_19144243 0.105 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2



SURP and G patch domain containing 2



chr11_+_134225909 0.104 ENST00000533324.1
GLB1L2
galactosidase, beta 1-like 2
chr8_+_22844913 0.104 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr17_-_27188984 0.103 ENST00000582320.2
MIR144
microRNA 451b
chr6_-_136788001 0.102 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr16_+_53469525 0.102 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr3_-_149051194 0.101 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr4_-_84256024 0.100 ENST00000311412.5
HPSE
heparanase
chr6_+_30853002 0.098 ENST00000421124.2
ENST00000512725.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr20_-_25320367 0.098 ENST00000450393.1
ENST00000491682.1
ABHD12

abhydrolase domain containing 12

chr17_-_15168624 0.092 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22


peripheral myelin protein 22


chr12_-_70093235 0.092 ENST00000266661.4
BEST3
bestrophin 3
chr2_+_9778872 0.091 ENST00000478468.1
RP11-521D12.1
RP11-521D12.1
chr22_+_40297105 0.091 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chrX_-_69509738 0.091 ENST00000374454.1
ENST00000239666.4
PDZD11

PDZ domain containing 11

chr10_+_73156664 0.090 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23



cadherin-related 23



chr20_+_46130619 0.090 ENST00000372004.3
NCOA3
nuclear receptor coactivator 3
chr2_-_27531313 0.087 ENST00000296099.2
UCN
urocortin
chr1_-_167906277 0.085 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr6_-_32908792 0.085 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr4_+_39699664 0.085 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K


ubiquitin-conjugating enzyme E2K


chr6_+_74405501 0.083 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr8_-_26371608 0.083 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr6_+_74405804 0.082 ENST00000287097.5
CD109
CD109 molecule
chr1_+_42922173 0.082 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS



phosphopantothenoylcysteine synthetase



chr5_-_94417314 0.082 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr7_-_75241096 0.081 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr9_+_115513003 0.080 ENST00000374232.3
SNX30
sorting nexin family member 30
chrX_-_48827976 0.080 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_89357179 0.080 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B


general transcription factor IIB


chr17_+_41150290 0.078 ENST00000589037.1
ENST00000253788.5
RPL27

ribosomal protein L27

chr11_-_113577052 0.078 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5



transmembrane protease, serine 5



chr3_+_125985620 0.077 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1

RP11-71E19.1

chr4_-_7069760 0.077 ENST00000264954.4
GRPEL1
GrpE-like 1, mitochondrial (E. coli)
chr2_-_179315490 0.076 ENST00000487082.1
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_128294929 0.075 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr1_-_234667504 0.073 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1

RP5-855F14.1

chr11_-_73693875 0.072 ENST00000536983.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_-_151936865 0.072 ENST00000535741.1
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr9_-_34729457 0.072 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr16_-_67517716 0.072 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr6_+_76330355 0.071 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr1_+_212475148 0.071 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chrX_+_134887233 0.070 ENST00000443882.1
CT45A3
cancer/testis antigen family 45, member A3
chr2_-_179315453 0.070 ENST00000432031.2
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr10_-_72142345 0.070 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20



leucine rich repeat containing 20




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.0 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.4 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) mitochondrial pyruvate transport(GO:0006850) pyruvate transmembrane transport(GO:1901475) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0032499 detection of peptidoglycan(GO:0032499)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.0 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.0 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.0 GO:0002519 natural killer cell tolerance induction(GO:0002519)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.5 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.4 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.3 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.5 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation