Motif ID: PBX2

Z-value: 0.097


Transcription factors associated with PBX2:

Gene SymbolEntrez IDGene Name
PBX2 ENSG00000204304.7 PBX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PBX2hg19_v2_chr6_-_32157947_32157992-0.713.3e-02Click!


Activity profile for motif PBX2.

activity profile for motif PBX2


Sorted Z-values histogram for motif PBX2

Sorted Z-values for motif PBX2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_190044480 0.037 ENST00000374866.3
 COL5A2
collagen, type V, alpha 2
chr11_-_111794446 0.037 ENST00000527950.1
 CRYAB
crystallin, alpha B
chr14_-_55658323 0.033 ENST00000554067.1
ENST00000247191.2
 DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr14_-_55658252 0.033 ENST00000395425.2
 DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr9_-_128246769 0.030 ENST00000444226.1
 MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_134528635 0.026 ENST00000445569.2
 CALD1
caldesmon 1
chr16_+_1128781 0.023 ENST00000293897.4
ENST00000562758.1
 SSTR5

somatostatin receptor 5

chr1_-_26231589 0.021 ENST00000374291.1
 STMN1
stathmin 1
chr12_-_28124903 0.016 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH


parathyroid hormone-like hormone


chr10_-_45474237 0.015 ENST00000448778.1
ENST00000298295.3
 C10orf10

chromosome 10 open reading frame 10

chr2_+_33661382 0.014 ENST00000402538.3
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_+_37962018 0.014 ENST00000504686.1
 PTTG2
pituitary tumor-transforming 2
chr22_+_42017987 0.013 ENST00000405506.1
 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_+_1832902 0.012 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
 NUBP2





nucleotide binding protein 2





chr3_-_52864680 0.010 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
 ITIH4




inter-alpha-trypsin inhibitor heavy chain family, member 4




chr5_-_39462390 0.010 ENST00000511792.1
 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr10_+_124320156 0.010 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
 DMBT1





deleted in malignant brain tumors 1





chr2_+_20646824 0.010 ENST00000272233.4
 RHOB
ras homolog family member B
chr3_+_129159039 0.009 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
 IFT122





intraflagellar transport 122 homolog (Chlamydomonas)





chr3_+_129158926 0.008 ENST00000347300.2
ENST00000296266.3
 IFT122

intraflagellar transport 122 homolog (Chlamydomonas)

chr17_+_7758374 0.008 ENST00000301599.6
ENST00000574668.1
 TMEM88

transmembrane protein 88

chrX_+_119737806 0.007 ENST00000371317.5
 MCTS1
malignant T cell amplified sequence 1
chr7_-_32529973 0.007 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
 LSM5



LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)



chr12_-_59917965 0.007 ENST00000548613.1
 RP11-272B17.2
Uncharacterized protein
chr18_-_72920372 0.006 ENST00000581620.1
ENST00000582437.1
 ZADH2

zinc binding alcohol dehydrogenase domain containing 2

chr14_+_27342334 0.005 ENST00000548170.1
ENST00000552926.1
 RP11-384J4.1

RP11-384J4.1

chr10_+_124320195 0.005 ENST00000359586.6
 DMBT1
deleted in malignant brain tumors 1
chr2_-_31440377 0.005 ENST00000444918.2
ENST00000403897.3
 CAPN14

calpain 14

chr1_-_39339777 0.004 ENST00000397572.2
 MYCBP
MYC binding protein
chr13_-_107220455 0.004 ENST00000400198.3
 ARGLU1
arginine and glutamate rich 1
chr13_+_108921977 0.004 ENST00000430559.1
ENST00000375887.4
 TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr7_-_112727774 0.004 ENST00000297146.3
ENST00000501255.2
 GPR85

G protein-coupled receptor 85

chr3_-_129158850 0.004 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
 MBD4



methyl-CpG binding domain protein 4



chr17_+_8191815 0.004 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
 RANGRF



RAN guanine nucleotide release factor



chr2_+_113033164 0.003 ENST00000409871.1
ENST00000343936.4
 ZC3H6

zinc finger CCCH-type containing 6

chr3_+_159943362 0.003 ENST00000326474.3
 C3orf80
chromosome 3 open reading frame 80
chr1_+_101702417 0.003 ENST00000305352.6
 S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_112013071 0.003 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
 SLC9C1


solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1


chr6_+_53976211 0.003 ENST00000503951.1
 MLIP
muscular LMNA-interacting protein
chr12_-_39734783 0.003 ENST00000552961.1
 KIF21A
kinesin family member 21A
chr16_-_11492366 0.003 ENST00000595360.1
 CTD-3088G3.8
Protein LOC388210
chr11_-_2162162 0.003 ENST00000381389.1
 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_234602305 0.002 ENST00000406651.1
 UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr3_+_188889737 0.002 ENST00000345063.3
 TPRG1
tumor protein p63 regulated 1
chr11_+_68228186 0.002 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
 PPP6R3












protein phosphatase 6, regulatory subunit 3












chr4_+_71017791 0.002 ENST00000502294.1
 C4orf40
chromosome 4 open reading frame 40
chr15_+_67418047 0.002 ENST00000540846.2
 SMAD3
SMAD family member 3
chr4_-_118006697 0.002 ENST00000310754.4
 TRAM1L1
translocation associated membrane protein 1-like 1
chr5_-_75008244 0.002 ENST00000510798.1
ENST00000446329.2
 POC5

POC5 centriolar protein

chr14_+_38033252 0.001 ENST00000554829.1
 RP11-356O9.1
RP11-356O9.1
chr14_+_64854958 0.001 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
 MTHFD1



methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase



chr12_-_28125638 0.001 ENST00000545234.1
 PTHLH
parathyroid hormone-like hormone
chr1_+_56880606 0.000 ENST00000451914.1
 RP4-710M16.2
RP4-710M16.2
chr4_+_71019903 0.000 ENST00000344526.5
 C4orf40
chromosome 4 open reading frame 40
chr3_-_47932759 0.000 ENST00000441748.2
ENST00000335271.5
 MAP4

microtubule-associated protein 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)