Motif ID: PBX1

Z-value: 0.395


Transcription factors associated with PBX1:

Gene SymbolEntrez IDGene Name
PBX1 ENSG00000185630.14 PBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528866_164528877-0.941.7e-04Click!


Activity profile for motif PBX1.

activity profile for motif PBX1


Sorted Z-values histogram for motif PBX1

Sorted Z-values for motif PBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_92929192 1.012 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chrX_-_1331527 0.925 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
CRLF2


cytokine receptor-like factor 2


chr22_+_29138013 0.766 ENST00000216027.3
ENST00000398941.2
HSCB

HscB mitochondrial iron-sulfur cluster co-chaperone

chr7_-_92747269 0.478 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr9_+_140135665 0.414 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr22_-_29137771 0.396 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2









checkpoint kinase 2









chr10_-_105845674 0.373 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr22_+_50981079 0.325 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr3_-_4927447 0.277 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr16_-_838329 0.237 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1





RNA pseudouridylate synthase domain containing 1





chr16_+_15596123 0.205 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr3_+_159557637 0.197 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr17_+_43239231 0.197 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2


hexamethylene bis-acetamide inducible 2


chr19_+_5681153 0.183 ENST00000577222.1
ENST00000579559.1
RPL36
HSD11B1L
ribosomal protein L36
hydroxysteroid (11-beta) dehydrogenase 1-like
chr6_-_36725157 0.179 ENST00000393189.2
CPNE5
copine V
chr19_-_5903714 0.175 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr12_-_15104040 0.174 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr17_+_45973516 0.173 ENST00000376741.4
SP2
Sp2 transcription factor
chr9_-_131486367 0.169 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12




zinc finger, DHHC-type containing 12




chr3_+_193853927 0.161 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr22_-_30642728 0.158 ENST00000403987.3
LIF
leukemia inhibitory factor
chr12_+_79258444 0.157 ENST00000261205.4
SYT1
synaptotagmin I
chr12_+_79258547 0.152 ENST00000457153.2
SYT1
synaptotagmin I
chr10_-_5638048 0.140 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr11_-_118966167 0.140 ENST00000530167.1
H2AFX
H2A histone family, member X
chr19_+_46498704 0.137 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61


coiled-coil domain containing 61


chr10_+_24738355 0.133 ENST00000307544.6
KIAA1217
KIAA1217
chr3_+_159570722 0.132 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr17_-_15519008 0.130 ENST00000261644.8
CDRT1
CMT1A duplicated region transcript 1
chr7_+_20370746 0.127 ENST00000222573.4
ITGB8
integrin, beta 8
chr7_+_7196565 0.126 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr9_-_123676827 0.125 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chrM_+_4431 0.117 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr14_+_74551650 0.114 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr6_-_31782813 0.114 ENST00000375654.4
HSPA1L
heat shock 70kDa protein 1-like
chr17_+_73663402 0.113 ENST00000355423.3
SAP30BP
SAP30 binding protein
chr11_+_844406 0.113 ENST00000397404.1
TSPAN4
tetraspanin 4
chr19_+_41770269 0.112 ENST00000378215.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_+_64794991 0.110 ENST00000352068.5
ENST00000525648.1
SNX15

sorting nexin 15

chr12_-_102455846 0.109 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr9_+_130565487 0.108 ENST00000373225.3
ENST00000431857.1
FPGS

folylpolyglutamate synthase

chr6_-_26250835 0.108 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr19_-_49121054 0.105 ENST00000546623.1
ENST00000084795.5
RPL18

ribosomal protein L18

chr17_+_8191815 0.104 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF



RAN guanine nucleotide release factor



chr19_+_19030497 0.104 ENST00000438170.2
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr9_+_106856831 0.102 ENST00000303219.8
ENST00000374787.3
SMC2

structural maintenance of chromosomes 2

chr19_+_19030478 0.101 ENST00000247003.4
DDX49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_+_41770236 0.099 ENST00000392006.3
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr3_-_53164423 0.098 ENST00000467048.1
ENST00000394738.3
ENST00000296292.3
RFT1


RFT1 homolog (S. cerevisiae)


chr7_+_23637763 0.095 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr19_-_14640005 0.095 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DNAJB1





DnaJ (Hsp40) homolog, subfamily B, member 1





chr17_+_21030260 0.094 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr12_-_10962767 0.093 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr14_+_23938891 0.092 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
NGDN


neuroguidin, EIF4E binding protein


chr7_-_72971934 0.091 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr2_+_234104079 0.090 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chrX_+_140084756 0.090 ENST00000449283.1
SPANXB2
SPANX family, member B2
chr17_-_40828969 0.089 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3


pleckstrin homology domain containing, family H (with MyTH4 domain) member 3


chr3_-_160283348 0.088 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr9_+_130565147 0.088 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS



folylpolyglutamate synthase



chr14_-_24584138 0.087 ENST00000558280.1
ENST00000561028.1
NRL

neural retina leucine zipper

chr3_+_111451321 0.085 ENST00000393923.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr15_-_60683326 0.084 ENST00000559350.1
ENST00000558986.1
ENST00000560389.1
ANXA2


annexin A2


chr6_-_15586238 0.084 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr12_-_102455902 0.084 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr8_+_37887772 0.083 ENST00000338825.4
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr14_+_88851874 0.082 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7



spermatogenesis associated 7



chr5_-_43313574 0.081 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr10_+_51549498 0.080 ENST00000358559.2
ENST00000298239.6
MSMB

microseminoprotein, beta-

chr22_-_22337146 0.080 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr17_+_46125707 0.080 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr3_-_71353892 0.080 ENST00000484350.1
FOXP1
forkhead box P1
chr6_-_7313381 0.077 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1






signal sequence receptor, alpha






chr12_-_95510743 0.075 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr1_-_173176452 0.075 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr3_+_122785895 0.073 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr1_-_98511756 0.072 ENST00000602984.1
ENST00000602852.1
MIR137HG

MIR137 host gene (non-protein coding)

chr1_-_28241226 0.072 ENST00000373912.3
ENST00000373909.3
RPA2

replication protein A2, 32kDa

chr17_-_40829026 0.071 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr16_-_69788816 0.069 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_+_27255806 0.069 ENST00000238788.9
ENST00000404032.3
TMEM214

transmembrane protein 214

chr16_-_30546141 0.068 ENST00000535210.1
ENST00000395094.3
ZNF747

zinc finger protein 747

chr16_-_11617444 0.068 ENST00000598234.1
CTD-3088G3.8
Protein LOC388210
chr14_+_38033252 0.066 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr4_+_77356248 0.066 ENST00000296043.6
SHROOM3
shroom family member 3
chr4_-_70080449 0.065 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr1_-_28241024 0.065 ENST00000313433.7
ENST00000444045.1
RPA2

replication protein A2, 32kDa

chr5_+_125759140 0.065 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr17_+_58755184 0.064 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr4_-_105416039 0.061 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr13_-_24895566 0.060 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr5_-_141703713 0.057 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr5_-_10761206 0.057 ENST00000432074.2
ENST00000230895.6
DAP

death-associated protein

chr12_+_21679220 0.056 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr22_+_35695793 0.056 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1





target of myb1 (chicken)





chrX_-_110655306 0.056 ENST00000371993.2
DCX
doublecortin
chr2_+_20646824 0.055 ENST00000272233.4
RHOB
ras homolog family member B
chr22_-_30642782 0.054 ENST00000249075.3
LIF
leukemia inhibitory factor
chr12_+_101988627 0.054 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr8_-_42360015 0.052 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr21_+_39668478 0.052 ENST00000398927.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr19_+_11485333 0.051 ENST00000312423.2
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr5_+_98109322 0.051 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr11_-_14380664 0.050 ENST00000545643.1
ENST00000256196.4
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr12_+_54402790 0.050 ENST00000040584.4
HOXC8
homeobox C8
chr2_+_201242941 0.050 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr11_+_66384053 0.050 ENST00000514361.3
ENST00000503028.2
ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000412278.2
ENST00000500635.2
RBM4

RBM14




RBM14-RBM4

RNA binding motif protein 4

RNA binding motif protein 14




RBM14-RBM4 readthrough

chr14_+_50065459 0.050 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr3_-_71114066 0.049 ENST00000485326.2
FOXP1
forkhead box P1
chr20_+_48909240 0.049 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chrX_+_53123314 0.049 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5




long intergenic non-protein coding RNA 1155




chr5_+_140213815 0.049 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr5_+_140207536 0.049 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr2_-_158182322 0.049 ENST00000420719.2
ENST00000409216.1
ERMN

ermin, ERM-like protein

chr6_-_27775694 0.049 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr10_+_69865866 0.048 ENST00000354393.2
MYPN
myopalladin
chr6_+_36839616 0.047 ENST00000359359.2
ENST00000510325.2
C6orf89

chromosome 6 open reading frame 89

chr17_+_73663470 0.047 ENST00000583536.1
SAP30BP
SAP30 binding protein
chr6_-_26199471 0.046 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr14_+_24584056 0.046 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_7758374 0.046 ENST00000301599.6
ENST00000574668.1
TMEM88

transmembrane protein 88

chr2_-_242626127 0.045 ENST00000445261.1
DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr6_-_110736742 0.045 ENST00000368924.3
ENST00000368923.3
DDO

D-aspartate oxidase

chr15_-_60695071 0.044 ENST00000557904.1
ANXA2
annexin A2
chr1_-_248845629 0.044 ENST00000342623.3
OR14I1
olfactory receptor, family 14, subfamily I, member 1
chr6_+_27114861 0.044 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr4_+_69962185 0.043 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_69681710 0.043 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr11_-_126870655 0.043 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr16_+_50059125 0.042 ENST00000427478.2
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr16_-_88729473 0.042 ENST00000301012.3
ENST00000569177.1
MVD

mevalonate (diphospho) decarboxylase

chr14_-_98152946 0.042 ENST00000556163.1
ENST00000355909.3
ENST00000554197.1
RP11-76E12.1


RP11-76E12.1


chr12_+_101988774 0.041 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1





myosin binding protein C, slow type





chr7_-_27142290 0.040 ENST00000222718.5
HOXA2
homeobox A2
chr11_+_47279155 0.040 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3


nuclear receptor subfamily 1, group H, member 3


chr5_+_151151471 0.039 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr14_+_24584372 0.039 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11




DDB1 and CUL4 associated factor 11




chr4_+_69962212 0.039 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr5_+_151151504 0.039 ENST00000356245.3
ENST00000507878.2
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr12_-_121342170 0.039 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr1_-_3713042 0.039 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr19_-_39881777 0.039 ENST00000595564.1
ENST00000221265.3
PAF1

Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)

chr2_+_201242715 0.038 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_-_10645724 0.038 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_198607801 0.037 ENST00000367379.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr8_-_91095099 0.037 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr7_-_559853 0.037 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr11_+_44117219 0.036 ENST00000532479.1
ENST00000527014.1
EXT2

exostosin glycosyltransferase 2

chr13_+_97928395 0.036 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr19_-_39881669 0.035 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr7_-_102184083 0.035 ENST00000379357.5
POLR2J3
polymerase (RNA) II (DNA directed) polypeptide J3
chr21_+_44313375 0.035 ENST00000354250.2
ENST00000340344.4
NDUFV3

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa

chr17_+_78518617 0.035 ENST00000537330.1
ENST00000570891.1
RPTOR

regulatory associated protein of MTOR, complex 1

chr10_-_31146615 0.034 ENST00000444692.2
ZNF438
zinc finger protein 438
chr17_+_43239191 0.034 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr10_+_69869237 0.034 ENST00000373675.3
MYPN
myopalladin
chr18_+_20494078 0.033 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8



retinoblastoma binding protein 8



chr6_+_25754927 0.033 ENST00000377905.4
ENST00000439485.2
SLC17A4

solute carrier family 17, member 4

chr8_-_101964738 0.032 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_+_46125685 0.032 ENST00000579889.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr16_+_19222479 0.030 ENST00000568433.1
SYT17
synaptotagmin XVII
chr10_+_5238793 0.030 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr4_-_69536346 0.030 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr1_-_54405773 0.030 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr14_+_29236269 0.029 ENST00000313071.4
FOXG1
forkhead box G1
chr12_+_21654714 0.028 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B


golgi transport 1B


chr9_-_101471479 0.028 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_41698927 0.028 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr4_+_187148556 0.028 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr4_-_48683188 0.027 ENST00000505759.1
FRYL
FRY-like
chr18_+_59854480 0.027 ENST00000256858.6
ENST00000398130.2
KIAA1468

KIAA1468

chr4_-_52883786 0.027 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr8_-_37411648 0.026 ENST00000519738.1
RP11-150O12.1
RP11-150O12.1
chrX_+_109602039 0.025 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr14_-_60097297 0.025 ENST00000395090.1
RTN1
reticulon 1
chr2_+_44396000 0.025 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B




protein phosphatase, Mg2+/Mn2+ dependent, 1B




chr3_+_120461484 0.025 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1



general transcription factor IIE, polypeptide 1, alpha 56kDa



chr4_+_56815102 0.025 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr13_-_46679144 0.025 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr22_-_22337204 0.024 ENST00000430142.1
ENST00000357179.5
TOP3B

topoisomerase (DNA) III beta

chr17_+_7477040 0.024 ENST00000581384.1
ENST00000577929.1
EIF4A1

eukaryotic translation initiation factor 4A1

chr7_+_107110488 0.024 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr4_+_88571429 0.024 ENST00000339673.6
ENST00000282479.7
DMP1

dentin matrix acidic phosphoprotein 1

chr16_-_20702578 0.023 ENST00000307493.4
ENST00000219151.4
ACSM1

acyl-CoA synthetase medium-chain family member 1

chr6_-_51952367 0.023 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chrX_+_142113704 0.022 ENST00000446864.1
ENST00000370504.3
SPANXN4

SPANX family, member N4

chr16_+_7560114 0.022 ENST00000570626.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_+_205473720 0.021 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr2_-_158182105 0.021 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr11_+_114166536 0.021 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr11_-_126870683 0.021 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr9_+_113431059 0.021 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr8_+_7801144 0.020 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr19_+_33072373 0.020 ENST00000586035.1
PDCD5
programmed cell death 5
chr2_+_233897382 0.020 ENST00000233840.3
NEU2
sialidase 2 (cytosolic sialidase)
chr6_-_51952418 0.020 ENST00000371117.3
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr19_+_14640372 0.019 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR




trans-2,3-enoyl-CoA reductase




chr3_-_129375556 0.019 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr3_+_120626919 0.018 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L




syntaxin binding protein 5-like




chr19_+_35417939 0.018 ENST00000601142.1
ENST00000426813.2
ZNF30

zinc finger protein 30


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.2 GO:2000974 trochlear nerve development(GO:0021558) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.2 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway