Motif ID: PAX8

Z-value: 0.526


Transcription factors associated with PAX8:

Gene SymbolEntrez IDGene Name
PAX8 ENSG00000125618.12 PAX8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_113999274-0.541.3e-01Click!


Activity profile for motif PAX8.

activity profile for motif PAX8


Sorted Z-values histogram for motif PAX8

Sorted Z-values for motif PAX8



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_49984894 0.886 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22


chromosome 8 open reading frame 22


chr6_-_134639235 0.505 ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_12766583 0.481 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_85661918 0.443 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr6_-_6711235 0.422 ENST00000432823.2
RP1-80N2.2
RP1-80N2.2
chr11_-_74022658 0.408 ENST00000427714.2
ENST00000331597.4
P4HA3

prolyl 4-hydroxylase, alpha polypeptide III

chr6_+_160542821 0.403 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr6_+_14117872 0.389 ENST00000379153.3
CD83
CD83 molecule
chr12_-_9360966 0.380 ENST00000261336.2
PZP
pregnancy-zone protein
chr6_+_160542870 0.377 ENST00000324965.4
ENST00000457470.2
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr11_-_9482010 0.338 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr3_+_164924716 0.324 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr6_+_71276596 0.311 ENST00000370474.3
C6orf57
chromosome 6 open reading frame 57
chr12_-_57410304 0.303 ENST00000441881.1
ENST00000458521.2
TAC3

tachykinin 3

chr8_-_57233103 0.301 ENST00000303749.3
ENST00000522671.1
SDR16C5

short chain dehydrogenase/reductase family 16C, member 5

chr6_+_72922590 0.294 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr19_+_17337473 0.285 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr6_-_134639180 0.265 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_7167980 0.257 ENST00000360817.5
ENST00000402681.3
C1S

complement component 1, s subcomponent

chr5_+_43603229 0.257 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr19_+_42041860 0.251 ENST00000483481.2
ENST00000494375.2
AC006129.4

AC006129.4

chr21_-_43816052 0.248 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr11_+_7626950 0.246 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_+_7618413 0.239 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr18_-_10748498 0.235 ENST00000579949.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr17_+_67410832 0.235 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr13_+_27844464 0.231 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr1_-_8585945 0.230 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr5_-_140027357 0.227 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr6_+_72926145 0.226 ENST00000425662.2
ENST00000453976.2
RIMS1

regulating synaptic membrane exocytosis 1

chr6_+_36853607 0.211 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89


chromosome 6 open reading frame 89


chr7_+_12544025 0.206 ENST00000443874.1
ENST00000424453.1
AC005281.1

AC005281.1

chr1_-_47131521 0.205 ENST00000542495.1
ENST00000532925.1
ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

chr6_+_24126350 0.204 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1


neurensin 1


chr10_+_35484793 0.203 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr6_+_72922505 0.203 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_118272610 0.198 ENST00000534438.1
RP11-770J1.5
Uncharacterized protein
chr14_-_70038032 0.197 ENST00000543986.1
CCDC177
coiled-coil domain containing 177
chr1_-_59012365 0.187 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1






OMA1 zinc metallopeptidase






chr17_+_9745786 0.181 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr3_-_110612323 0.179 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr10_+_12391685 0.179 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr11_+_63742050 0.178 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr6_-_82462425 0.173 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chrX_+_17653413 0.162 ENST00000398097.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr11_+_20044375 0.160 ENST00000525322.1
ENST00000530408.1
NAV2

neuron navigator 2

chr11_-_129062093 0.159 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr16_-_28518153 0.158 ENST00000356897.1
IL27
interleukin 27
chr2_-_84686552 0.158 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr7_+_149535455 0.157 ENST00000223210.4
ENST00000460379.1
ZNF862

zinc finger protein 862

chr2_+_173724771 0.157 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr3_-_110612059 0.156 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr7_-_99277610 0.154 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr6_+_151773583 0.152 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr17_-_1508379 0.152 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr3_-_111852128 0.152 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr11_-_47870019 0.148 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr11_+_20044600 0.147 ENST00000311043.8
NAV2
neuron navigator 2
chr11_-_47869865 0.147 ENST00000530326.1
ENST00000532747.1
NUP160

nucleoporin 160kDa

chr1_+_89990378 0.143 ENST00000449440.1
LRRC8B
leucine rich repeat containing 8 family, member B
chr17_-_44657017 0.141 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ARL17A





ADP-ribosylation factor-like 17A





chr6_+_30844192 0.136 ENST00000502955.1
ENST00000505066.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr6_+_52285046 0.136 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr3_-_6847096 0.136 ENST00000454410.2
ENST00000424366.1
ENST00000417482.1
ENST00000412629.1
GRM7-AS3



GRM7 antisense RNA 3



chr17_+_79934670 0.133 ENST00000581484.1
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_9482551 0.133 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143




zinc finger protein 143




chr1_-_119683251 0.130 ENST00000369426.5
ENST00000235521.4
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr3_-_141719195 0.129 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_+_118950325 0.128 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr16_+_75690093 0.127 ENST00000564671.2
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr8_+_59323823 0.125 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr1_+_186649754 0.124 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr3_+_186501979 0.123 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr19_-_44860820 0.123 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112


zinc finger protein 112


chr16_-_31519691 0.122 ENST00000567994.1
ENST00000430477.2
ENST00000570164.1
ENST00000327237.2
C16orf58



chromosome 16 open reading frame 58



chr16_-_86383240 0.121 ENST00000595169.1
ENST00000598994.1
ENST00000599619.1
ENST00000599664.1
LINC00917



long intergenic non-protein coding RNA 917



chr10_-_81203972 0.120 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr10_-_104597286 0.119 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr11_-_47870091 0.119 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr16_+_2083265 0.118 ENST00000565855.1
ENST00000566198.1
SLC9A3R2

solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2

chr10_+_135340859 0.116 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr4_-_89951028 0.115 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr8_-_66474884 0.111 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr11_+_65851443 0.111 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr17_-_67057047 0.111 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9


ATP-binding cassette, sub-family A (ABC1), member 9


chr1_-_119682812 0.110 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr11_+_9482512 0.110 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143




zinc finger protein 143




chr1_-_165668100 0.108 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr9_-_128246769 0.105 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_75677354 0.105 ENST00000461263.2
ENST00000315758.5
ENST00000443006.1
MDH2


malate dehydrogenase 2, NAD (mitochondrial)


chr17_+_6918093 0.104 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr11_+_5617858 0.104 ENST00000380097.3
TRIM6
tripartite motif containing 6
chr1_-_198509804 0.103 ENST00000489986.1
ENST00000367382.1
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr17_-_44439084 0.102 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ARL17B





ADP-ribosylation factor-like 17B





chr5_-_176943917 0.100 ENST00000330503.7
DDX41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr19_+_9938562 0.099 ENST00000586895.1
ENST00000358666.3
ENST00000590068.1
ENST00000593087.1
UBL5



ubiquitin-like 5



chr13_+_31309645 0.097 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr11_+_20044096 0.097 ENST00000533917.1
NAV2
neuron navigator 2
chr11_-_8816375 0.096 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chrX_+_23925918 0.095 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr8_-_117043 0.092 ENST00000320901.3
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr7_+_140396756 0.090 ENST00000460088.1
ENST00000472695.1
NDUFB2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

chr13_+_111748183 0.089 ENST00000422994.1
LINC00368
long intergenic non-protein coding RNA 368
chr11_+_59705928 0.088 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr6_+_31126291 0.087 ENST00000376257.3
ENST00000376255.4
TCF19

transcription factor 19

chr17_+_7461849 0.086 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr8_+_21915368 0.084 ENST00000265800.5
ENST00000517418.1
DMTN

dematin actin binding protein

chr14_+_76452090 0.083 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
IFT43


intraflagellar transport 43 homolog (Chlamydomonas)


chr7_+_107531580 0.083 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD


dihydrolipoamide dehydrogenase


chr3_+_150264458 0.079 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr9_-_92020841 0.079 ENST00000433650.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr14_+_58797974 0.078 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr7_+_140396946 0.076 ENST00000476470.1
ENST00000471136.1
NDUFB2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa

chr9_+_124048864 0.074 ENST00000545652.1
GSN
gelsolin
chr17_+_7462031 0.074 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr4_+_71600063 0.072 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr1_-_52520828 0.072 ENST00000610127.1
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr4_+_154073469 0.071 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr19_+_52901094 0.071 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
ZNF528





zinc finger protein 528





chr2_-_87248975 0.070 ENST00000409310.2
ENST00000355705.3
PLGLB1

plasminogen-like B1

chr1_+_28099700 0.069 ENST00000440806.2
STX12
syntaxin 12
chr3_-_78719376 0.069 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr15_+_77223960 0.069 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr19_+_35630926 0.068 ENST00000588081.1
ENST00000589121.1
FXYD1

FXYD domain containing ion transport regulator 1

chr3_+_150264555 0.068 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr17_+_7462103 0.067 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_+_95115210 0.066 ENST00000428113.1
ENST00000325885.5
ASB4

ankyrin repeat and SOCS box containing 4

chr12_-_54652060 0.066 ENST00000552562.1
CBX5
chromobox homolog 5
chr4_+_71600144 0.065 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr17_+_7461613 0.065 ENST00000438470.1
ENST00000436057.1
TNFSF13

tumor necrosis factor (ligand) superfamily, member 13

chr19_+_782755 0.064 ENST00000606242.1
ENST00000586061.1
AC006273.5

AC006273.5

chr17_+_7461781 0.064 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr15_+_77224045 0.064 ENST00000320963.5
ENST00000394883.3
RCN2

reticulocalbin 2, EF-hand calcium binding domain

chr1_+_171283331 0.064 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr16_-_30773372 0.063 ENST00000545825.1
ENST00000541260.1
C16orf93

chromosome 16 open reading frame 93

chr6_+_63921399 0.062 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr4_+_120860695 0.060 ENST00000505122.2
RP11-700N1.1
RP11-700N1.1
chr19_+_9361606 0.059 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr1_-_223853425 0.058 ENST00000366873.2
ENST00000419193.2
CAPN8

calpain 8

chr12_+_122516626 0.058 ENST00000319080.7
MLXIP
MLX interacting protein
chr1_+_197382957 0.058 ENST00000367397.1
CRB1
crumbs homolog 1 (Drosophila)
chr6_+_135502466 0.057 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr12_+_26348582 0.055 ENST00000535504.1
SSPN
sarcospan
chr2_+_191334212 0.055 ENST00000444317.1
ENST00000535751.1
MFSD6

major facilitator superfamily domain containing 6

chr8_-_66546439 0.054 ENST00000276569.3
ARMC1
armadillo repeat containing 1
chr7_+_129984630 0.054 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chrX_+_134887233 0.054 ENST00000443882.1
CT45A3
cancer/testis antigen family 45, member A3
chr14_-_91710852 0.054 ENST00000535815.1
ENST00000529102.1
GPR68

G protein-coupled receptor 68

chr10_+_127371798 0.053 ENST00000596068.1
ENST00000607914.1
ENST00000415305.2
ENST00000449693.1
RP11-383C5.3



RP11-383C5.3



chr5_+_140027355 0.053 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
IK


IK cytokine, down-regulator of HLA II


chr11_-_104905840 0.053 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr2_-_37193606 0.052 ENST00000379213.2
ENST00000263918.4
STRN

striatin, calmodulin binding protein

chr17_+_48624450 0.052 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20


spermatogenesis associated 20


chr19_+_54704610 0.051 ENST00000302907.4
RPS9
ribosomal protein S9
chr17_-_72588422 0.050 ENST00000375352.1
CD300LD
CD300 molecule-like family member d
chr13_-_107214291 0.050 ENST00000375926.1
ARGLU1
arginine and glutamate rich 1
chr5_+_69321074 0.050 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
SERF1B



small EDRK-rich factor 1B (centromeric)



chr19_+_54704718 0.049 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
RPS9


ribosomal protein S9


chr1_+_367640 0.049 ENST00000426406.1
OR4F29
olfactory receptor, family 4, subfamily F, member 29
chr6_+_135502408 0.049 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr7_+_140396465 0.048 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2





NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa





chr1_-_8586084 0.047 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr12_-_89919965 0.046 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr17_-_42100474 0.046 ENST00000585950.1
ENST00000592127.1
ENST00000589334.1
TMEM101


transmembrane protein 101


chr17_-_73267304 0.046 ENST00000579297.1
ENST00000580571.1
MIF4GD

MIF4G domain containing

chr15_+_89584447 0.045 ENST00000565938.1
RP11-326A19.4
RP11-326A19.4
chr1_-_161600822 0.044 ENST00000534776.1
ENST00000540048.1
FCGR3B
FCGR3A
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr7_+_80275663 0.044 ENST00000413265.1
CD36
CD36 molecule (thrombospondin receptor)
chr8_+_124428959 0.044 ENST00000287387.2
ENST00000523984.1
WDYHV1

WDYHV motif containing 1

chr3_-_112329110 0.044 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr1_-_161600990 0.043 ENST00000531221.1
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr17_-_67057114 0.043 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_-_144826682 0.042 ENST00000358615.4
ENST00000437468.2
GYPE

glycophorin E (MNS blood group)

chr1_-_161600942 0.042 ENST00000421702.2
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr2_-_132589601 0.041 ENST00000437330.1
AC103564.7
AC103564.7
chr7_+_150413645 0.041 ENST00000307194.5
GIMAP1
GTPase, IMAP family member 1
chr4_-_80329356 0.041 ENST00000358842.3
GK2
glycerol kinase 2
chr7_+_90012986 0.041 ENST00000416322.1
CLDN12
claudin 12
chr8_+_27168988 0.040 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B


protein tyrosine kinase 2 beta


chr17_-_67057203 0.039 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr12_+_133757995 0.039 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268









zinc finger protein 268









chr4_-_16077741 0.039 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1


prominin 1


chr8_-_19093121 0.038 ENST00000518417.1
RP11-1080G15.1
RP11-1080G15.1
chr3_-_150264272 0.038 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1


stress-associated endoplasmic reticulum protein 1


chr17_+_5031687 0.037 ENST00000250066.6
ENST00000304328.5
USP6

ubiquitin specific peptidase 6 (Tre-2 oncogene)

chrX_+_129535937 0.037 ENST00000305536.6
ENST00000370947.1
RBMX2

RNA binding motif protein, X-linked 2

chr18_-_21017817 0.037 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241





transmembrane protein 241





chr1_+_160709029 0.036 ENST00000444090.2
ENST00000441662.2
SLAMF7

SLAM family member 7

chr16_-_15736345 0.036 ENST00000549219.1
KIAA0430
KIAA0430
chr14_-_54425475 0.035 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr6_+_135502501 0.034 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr1_+_16083123 0.033 ENST00000510393.1
ENST00000430076.1
FBLIM1

filamin binding LIM protein 1

chr1_+_155006300 0.033 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr19_-_35992780 0.033 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr19_+_16296191 0.032 ENST00000589852.1
ENST00000263384.7
ENST00000588367.1
ENST00000587351.1
FAM32A



family with sequence similarity 32, member A



chr17_+_7461580 0.032 ENST00000483039.1
ENST00000396542.1
TNFSF13

tumor necrosis factor (ligand) superfamily, member 13

chrY_-_20935572 0.031 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2


heat shock transcription factor, Y linked 2


chr20_-_1373682 0.031 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr17_-_73267214 0.031 ENST00000580717.1
ENST00000577542.1
ENST00000579612.1
ENST00000245551.5
MIF4GD



MIF4G domain containing



chr11_-_62457371 0.031 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.9 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.4 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.7 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.0 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.0 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics