Motif ID: PAX6

Z-value: 0.440


Transcription factors associated with PAX6:

Gene SymbolEntrez IDGene Name
PAX6 ENSG00000007372.16 PAX6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX6hg19_v2_chr11_-_31832207_31832226-0.422.7e-01Click!


Activity profile for motif PAX6.

activity profile for motif PAX6


Sorted Z-values histogram for motif PAX6

Sorted Z-values for motif PAX6



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_74648848 0.244 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
 WDR54


WD repeat domain 54


chr4_+_129349188 0.243 ENST00000511497.1
 RP11-420A23.1
RP11-420A23.1
chr4_-_187517928 0.237 ENST00000512772.1
 FAT1
FAT atypical cadherin 1
chr8_-_18711866 0.225 ENST00000519851.1
 PSD3
pleckstrin and Sec7 domain containing 3
chr1_+_203765437 0.211 ENST00000550078.1
 ZBED6
zinc finger, BED-type containing 6
chr6_-_64029879 0.200 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
 LGSN


lengsin, lens protein with glutamine synthetase domain


chr4_+_87928140 0.180 ENST00000307808.6
 AFF1
AF4/FMR2 family, member 1
chr1_+_203651937 0.163 ENST00000341360.2
 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr8_+_49984894 0.161 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
 C8orf22


chromosome 8 open reading frame 22


chr18_-_37380230 0.157 ENST00000591629.1
 LINC00669
long intergenic non-protein coding RNA 669
chr19_+_35820064 0.154 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
 CD22











CD22 molecule











chr8_-_95487272 0.154 ENST00000297592.5
 RAD54B
RAD54 homolog B (S. cerevisiae)
chr18_+_18822185 0.153 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
 GREB1L


growth regulation by estrogen in breast cancer-like


chr3_-_196910477 0.145 ENST00000447466.1
 DLG1
discs, large homolog 1 (Drosophila)
chr5_-_173173171 0.145 ENST00000517733.1
ENST00000518902.1
 CTB-43E15.3

CTB-43E15.3

chr11_-_28129656 0.144 ENST00000263181.6
 KIF18A
kinesin family member 18A
chr1_+_207925391 0.136 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
 CD46











CD46 molecule, complement regulatory protein











chr1_+_167298281 0.133 ENST00000367862.5
 POU2F1
POU class 2 homeobox 1
chr1_+_163291732 0.129 ENST00000271452.3
 NUF2
NUF2, NDC80 kinetochore complex component
chr1_-_8586084 0.127 ENST00000464972.1
 RERE
arginine-glutamic acid dipeptide (RE) repeats
chr13_-_24007815 0.124 ENST00000382298.3
 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr17_-_77023683 0.123 ENST00000581579.1
 C1QTNF1-AS1
C1QTNF1 antisense RNA 1
chr8_+_67104323 0.123 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
 LINC00967


long intergenic non-protein coding RNA 967


chr16_-_18937726 0.123 ENST00000389467.3
ENST00000446231.2
 SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr1_-_8585945 0.123 ENST00000377464.1
 RERE
arginine-glutamic acid dipeptide (RE) repeats
chr12_+_10460417 0.121 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
 KLRD1


killer cell lectin-like receptor subfamily D, member 1


chr8_+_142402089 0.121 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
 PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr12_+_122516626 0.120 ENST00000319080.7
 MLXIP
MLX interacting protein
chr10_-_118765081 0.120 ENST00000392903.2
ENST00000355371.4
 KIAA1598

KIAA1598

chr10_-_75226166 0.116 ENST00000544628.1
 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr2_+_196521845 0.114 ENST00000359634.5
ENST00000412905.1
 SLC39A10

solute carrier family 39 (zinc transporter), member 10

chr11_-_101778665 0.112 ENST00000534527.1
 ANGPTL5
angiopoietin-like 5
chr18_+_32173276 0.109 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
 DTNA








dystrobrevin, alpha








chr11_+_28129795 0.108 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
 METTL15



methyltransferase like 15



chr17_-_77023723 0.107 ENST00000577521.1
 C1QTNF1-AS1
C1QTNF1 antisense RNA 1
chr10_-_118764862 0.106 ENST00000260777.10
 KIAA1598
KIAA1598
chrX_+_37545012 0.105 ENST00000378616.3
 XK
X-linked Kx blood group (McLeod syndrome)
chr3_+_15045419 0.104 ENST00000406272.2
 NR2C2
nuclear receptor subfamily 2, group C, member 2
chr9_+_127023704 0.102 ENST00000373596.1
ENST00000425237.1
 NEK6

NIMA-related kinase 6

chr3_-_196910721 0.101 ENST00000443183.1
 DLG1
discs, large homolog 1 (Drosophila)
chr2_+_196521903 0.100 ENST00000541054.1
 SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr16_-_15982440 0.100 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
 FOPNL






FGFR1OP N-terminal like






chrX_-_138914394 0.099 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
 ATP11C



ATPase, class VI, type 11C



chr5_+_85913721 0.099 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
 COX7C


cytochrome c oxidase subunit VIIc


chr2_+_196521458 0.097 ENST00000409086.3
 SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_+_93954039 0.094 ENST00000265140.5
 ANKRD32
ankyrin repeat domain 32
chr18_+_18822216 0.094 ENST00000269218.6
 GREB1L
growth regulation by estrogen in breast cancer-like
chr14_+_61995722 0.092 ENST00000556347.1
 RP11-47I22.4
RP11-47I22.4
chr2_+_196522032 0.091 ENST00000418005.1
 SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr18_-_21242729 0.091 ENST00000585908.2
 ANKRD29
ankyrin repeat domain 29
chr17_-_58499766 0.091 ENST00000588898.1
 USP32
ubiquitin specific peptidase 32
chr9_-_128412696 0.090 ENST00000420643.1
 MAPKAP1
mitogen-activated protein kinase associated protein 1
chr4_-_88141615 0.090 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
 KLHL8


kelch-like family member 8


chr3_+_171561127 0.089 ENST00000334567.5
ENST00000450693.1
 TMEM212

transmembrane protein 212

chr18_-_10855434 0.086 ENST00000579112.1
 PIEZO2
piezo-type mechanosensitive ion channel component 2
chr2_+_109204743 0.086 ENST00000332345.6
 LIMS1
LIM and senescent cell antigen-like domains 1
chr1_+_87380299 0.086 ENST00000370551.4
ENST00000370550.5
 HS2ST1

heparan sulfate 2-O-sulfotransferase 1

chr1_+_104068562 0.086 ENST00000423855.2
 RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr7_+_102292796 0.085 ENST00000436228.2
 SPDYE2B
speedy/RINGO cell cycle regulator family member E2B
chr10_+_12110963 0.085 ENST00000263035.4
ENST00000437298.1
 DHTKD1

dehydrogenase E1 and transketolase domain containing 1

chr10_+_97471508 0.083 ENST00000453258.2
 ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr14_+_24099318 0.082 ENST00000432832.2
 DHRS2
dehydrogenase/reductase (SDR family) member 2
chr21_+_39628780 0.081 ENST00000417042.1
 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_26156551 0.080 ENST00000304218.3
 HIST1H1E
histone cluster 1, H1e
chr5_+_321810 0.078 ENST00000514523.1
 AHRR
aryl-hydrocarbon receptor repressor
chr16_+_89228757 0.077 ENST00000565008.1
 LINC00304
long intergenic non-protein coding RNA 304
chr12_+_47473369 0.077 ENST00000546455.1
 PCED1B
PC-esterase domain containing 1B
chr19_-_54327542 0.077 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
 NLRP12







NLR family, pyrin domain containing 12







chr1_-_211666259 0.077 ENST00000367002.4
 RD3
retinal degeneration 3
chr2_+_109204909 0.076 ENST00000393310.1
 LIMS1
LIM and senescent cell antigen-like domains 1
chr12_-_2986107 0.075 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
 FOXM1


forkhead box M1


chr14_+_24407940 0.075 ENST00000354854.1
 DHRS4-AS1
DHRS4-AS1
chr5_-_141338377 0.074 ENST00000510041.1
 PCDH12
protocadherin 12
chr7_+_65552756 0.073 ENST00000450043.1
 AC068533.7
AC068533.7
chr9_-_14180778 0.072 ENST00000380924.1
ENST00000543693.1
 NFIB

nuclear factor I/B

chr14_+_57671888 0.070 ENST00000391612.1
 AL391152.1
AL391152.1
chr5_+_42756903 0.068 ENST00000361970.5
ENST00000388827.4
 CCDC152

coiled-coil domain containing 152

chr3_-_142297668 0.068 ENST00000350721.4
ENST00000383101.3
 ATR

ataxia telangiectasia and Rad3 related

chr2_-_86116020 0.068 ENST00000525834.2
 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr3_-_111852128 0.067 ENST00000308910.4
 GCSAM
germinal center-associated, signaling and motility
chr17_-_76824975 0.067 ENST00000586066.2
 USP36
ubiquitin specific peptidase 36
chrX_-_80457385 0.066 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
 HMGN5


high mobility group nucleosome binding domain 5


chr8_-_62602327 0.066 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
 ASPH









aspartate beta-hydroxylase









chr2_+_172778952 0.066 ENST00000392584.1
ENST00000264108.4
 HAT1

histone acetyltransferase 1

chr1_-_43282945 0.065 ENST00000537227.1
 CCDC23
coiled-coil domain containing 23
chr10_-_16563870 0.065 ENST00000298943.3
 C1QL3
complement component 1, q subcomponent-like 3
chr18_-_21242833 0.065 ENST00000586087.1
ENST00000592179.1
 ANKRD29

ankyrin repeat domain 29

chrX_+_148769880 0.064 ENST00000412632.2
 MAGEA11
melanoma antigen family A, 11
chr17_+_7239821 0.064 ENST00000158762.3
ENST00000570457.2
 ACAP1

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

chr4_+_70894130 0.063 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3


histatin 3


chr19_-_51920873 0.063 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
 SIGLEC10


sialic acid binding Ig-like lectin 10


chr21_-_18985230 0.063 ENST00000457956.1
ENST00000348354.6
 BTG3

BTG family, member 3

chr3_+_140981456 0.062 ENST00000504264.1
 ACPL2
acid phosphatase-like 2
chr13_+_25875785 0.062 ENST00000381747.3
 NUPL1
nucleoporin like 1
chr3_+_51663407 0.062 ENST00000432863.1
ENST00000296477.3
 RAD54L2

RAD54-like 2 (S. cerevisiae)

chr7_+_133615169 0.061 ENST00000541309.1
 EXOC4
exocyst complex component 4
chr12_+_59194154 0.061 ENST00000548969.1
 RP11-362K2.2
Protein LOC100506869
chr4_-_88141755 0.061 ENST00000273963.5
 KLHL8
kelch-like family member 8
chr6_-_30684898 0.060 ENST00000422266.1
ENST00000416571.1
 MDC1

mediator of DNA-damage checkpoint 1

chr1_-_188856565 0.059 ENST00000414765.1
 RP11-316I3.2
RP11-316I3.2
chr16_-_71264558 0.059 ENST00000448089.2
ENST00000393550.2
ENST00000448691.1
ENST00000393567.2
ENST00000321489.5
ENST00000539973.1
ENST00000288168.10
ENST00000545267.1
ENST00000541601.1
ENST00000538248.1
 HYDIN









HYDIN, axonemal central pair apparatus protein









chr13_+_25875662 0.059 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
 NUPL1


nucleoporin like 1


chr18_-_21242774 0.059 ENST00000322980.9
 ANKRD29
ankyrin repeat domain 29
chr4_+_70916119 0.059 ENST00000246896.3
ENST00000511674.1
 HTN1

histatin 1

chr14_+_29241910 0.058 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
 C14orf23


chromosome 14 open reading frame 23


chrX_-_6146876 0.058 ENST00000381095.3
 NLGN4X
neuroligin 4, X-linked
chr6_+_147527103 0.057 ENST00000179882.6
 STXBP5
syntaxin binding protein 5 (tomosyn)
chr3_-_119379719 0.057 ENST00000493094.1
 POPDC2
popeye domain containing 2
chr1_-_86174065 0.057 ENST00000370574.3
ENST00000431532.2
 ZNHIT6

zinc finger, HIT-type containing 6

chr7_-_138348969 0.057 ENST00000436657.1
 SVOPL
SVOP-like
chr2_-_86116093 0.056 ENST00000377332.3
 ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_-_102401469 0.056 ENST00000260227.4
 MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr10_+_18240834 0.056 ENST00000377371.3
ENST00000539911.1
 SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr2_+_145780767 0.056 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
 TEX41











testis expressed 41 (non-protein coding)











chr8_+_59323823 0.055 ENST00000399598.2
 UBXN2B
UBX domain protein 2B
chr19_-_22806764 0.055 ENST00000598042.1
 AC011516.2
AC011516.2
chr8_+_121457642 0.055 ENST00000305949.1
 MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr20_+_62887081 0.055 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
 PCMTD2




protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2




chr5_+_119799927 0.054 ENST00000407149.2
ENST00000379551.2
 PRR16

proline rich 16

chr9_-_13279563 0.054 ENST00000541718.1
 MPDZ
multiple PDZ domain protein
chr12_-_47473425 0.053 ENST00000550413.1
 AMIGO2
adhesion molecule with Ig-like domain 2
chr12_-_69080590 0.053 ENST00000433116.2
ENST00000500695.2
 RP11-637A17.2

RP11-637A17.2

chr19_-_51920835 0.053 ENST00000442846.3
ENST00000530476.1
 SIGLEC10

sialic acid binding Ig-like lectin 10

chr12_-_47473707 0.053 ENST00000429635.1
 AMIGO2
adhesion molecule with Ig-like domain 2
chr10_+_13628921 0.052 ENST00000378572.3
 PRPF18
pre-mRNA processing factor 18
chrX_+_77154935 0.052 ENST00000481445.1
 COX7B
cytochrome c oxidase subunit VIIb
chr2_+_114195268 0.052 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
 CBWD2


COBW domain containing 2


chr6_-_131291572 0.052 ENST00000529208.1
 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_-_122512619 0.051 ENST00000383659.1
ENST00000306103.2
 HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr12_-_6716569 0.051 ENST00000544040.1
ENST00000545942.1
 CHD4

chromodomain helicase DNA binding protein 4

chr12_-_106697974 0.051 ENST00000553039.1
 CKAP4
cytoskeleton-associated protein 4
chr3_-_111852061 0.049 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
 GCSAM



germinal center-associated, signaling and motility



chr8_-_121457332 0.048 ENST00000518918.1
 MRPL13
mitochondrial ribosomal protein L13
chr3_-_101232019 0.048 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
 SENP7





SUMO1/sentrin specific peptidase 7





chr1_+_26758849 0.048 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
 DHDDS






dehydrodolichyl diphosphate synthase






chr6_-_117923520 0.047 ENST00000368498.2
 GOPC
golgi-associated PDZ and coiled-coil motif containing
chr15_-_78358465 0.047 ENST00000435468.1
 TBC1D2B
TBC1 domain family, member 2B
chr16_-_73178346 0.047 ENST00000358463.2
 C16orf47
chromosome 16 open reading frame 47
chr1_+_180897269 0.047 ENST00000367587.1
 KIAA1614
KIAA1614
chr4_+_139694701 0.047 ENST00000502606.1
 RP11-98O2.1
RP11-98O2.1
chr5_+_17404147 0.047 ENST00000507730.1
 RP11-321E2.3
RP11-321E2.3
chr19_+_35939154 0.046 ENST00000599180.2
 FFAR2
free fatty acid receptor 2
chr20_+_9966728 0.046 ENST00000449270.1
 RP5-839B4.8
RP5-839B4.8
chr11_-_57298187 0.045 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
 TIMM10


translocase of inner mitochondrial membrane 10 homolog (yeast)


chr14_+_32547434 0.045 ENST00000556191.1
ENST00000554090.1
 ARHGAP5

Rho GTPase activating protein 5

chr16_-_18911366 0.045 ENST00000565224.1
 SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_-_27469383 0.044 ENST00000519742.1
 CLU
clusterin
chr16_+_4897912 0.044 ENST00000545171.1
 UBN1
ubinuclein 1
chr10_-_27389320 0.044 ENST00000436985.2
 ANKRD26
ankyrin repeat domain 26
chr2_-_136743169 0.044 ENST00000264161.4
 DARS
aspartyl-tRNA synthetase
chr9_-_116861337 0.043 ENST00000374118.3
 KIF12
kinesin family member 12
chr7_-_91808845 0.042 ENST00000343318.5
 LRRD1
leucine-rich repeats and death domain containing 1
chr7_+_90012986 0.042 ENST00000416322.1
 CLDN12
claudin 12
chr1_-_89458415 0.042 ENST00000370491.3
ENST00000321792.5
 CCBL2
RBMXL1
cysteine conjugate-beta lyase 2
RNA binding motif protein, X-linked-like 1
chr12_+_58937907 0.042 ENST00000546977.1
 RP11-362K2.2
Protein LOC100506869
chr12_-_3982511 0.041 ENST00000427057.2
ENST00000228820.4
 PARP11

poly (ADP-ribose) polymerase family, member 11

chr10_+_35894338 0.041 ENST00000321660.1
 GJD4
gap junction protein, delta 4, 40.1kDa
chr12_-_70093065 0.041 ENST00000553096.1
 BEST3
bestrophin 3
chr8_-_17103951 0.040 ENST00000520178.1
 CNOT7
CCR4-NOT transcription complex, subunit 7
chr14_+_56127960 0.040 ENST00000553624.1
 KTN1
kinectin 1 (kinesin receptor)
chr12_-_70093111 0.039 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
 BEST3



bestrophin 3



chr7_-_102252589 0.039 ENST00000520042.1
 RASA4
RAS p21 protein activator 4
chr19_+_51628165 0.039 ENST00000250360.3
ENST00000440804.3
 SIGLEC9

sialic acid binding Ig-like lectin 9

chr22_-_30968839 0.039 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
 GAL3ST1




galactose-3-O-sulfotransferase 1




chr8_-_121457608 0.038 ENST00000306185.3
 MRPL13
mitochondrial ribosomal protein L13
chr7_+_39773160 0.038 ENST00000340510.4
 LINC00265
long intergenic non-protein coding RNA 265
chr17_-_2415169 0.038 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
 METTL16


methyltransferase like 16


chr20_-_32308028 0.038 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
 PXMP4


peroxisomal membrane protein 4, 24kDa


chr12_+_27175476 0.038 ENST00000546323.1
ENST00000282892.3
 MED21

mediator complex subunit 21

chr12_+_69080734 0.037 ENST00000378905.2
 NUP107
nucleoporin 107kDa
chr1_-_229230644 0.037 ENST00000433734.1
 RP5-1065P14.2
RP5-1065P14.2
chr16_+_72088376 0.037 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
 HP








HPR
haptoglobin








haptoglobin-related protein
chr1_-_43282906 0.037 ENST00000372521.4
 CCDC23
coiled-coil domain containing 23
chr10_-_17243579 0.037 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
 TRDMT1






tRNA aspartic acid methyltransferase 1






chr9_+_42704004 0.036 ENST00000457288.1
 CBWD7
COBW domain containing 7
chr10_+_116524547 0.035 ENST00000436932.1
 RP11-106M7.1
RP11-106M7.1
chr4_-_174320687 0.035 ENST00000296506.3
 SCRG1
stimulator of chondrogenesis 1
chr3_-_15563229 0.035 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
 COLQ




collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase




chr7_-_229557 0.035 ENST00000514988.1
 AC145676.2
Uncharacterized protein
chr1_-_23504176 0.035 ENST00000302291.4
 LUZP1
leucine zipper protein 1
chr2_+_191334212 0.034 ENST00000444317.1
ENST00000535751.1
 MFSD6

major facilitator superfamily domain containing 6

chr8_+_21882244 0.034 ENST00000289820.6
ENST00000381530.5
 NPM2

nucleophosmin/nucleoplasmin 2

chr1_-_156722015 0.034 ENST00000368209.5
 HDGF
hepatoma-derived growth factor
chr2_-_161056802 0.033 ENST00000283249.2
ENST00000409872.1
 ITGB6

integrin, beta 6

chr4_-_65275162 0.033 ENST00000381210.3
ENST00000507440.1
 TECRL

trans-2,3-enoyl-CoA reductase-like

chr22_-_17702729 0.033 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
 CECR1


cat eye syndrome chromosome region, candidate 1


chr2_-_220110111 0.032 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
 GLB1L



galactosidase, beta 1-like



chr6_-_131321863 0.032 ENST00000528282.1
 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_-_80926457 0.032 ENST00000563626.1
ENST00000562231.1
 RP11-314O13.1

RP11-314O13.1

chr5_+_147691979 0.032 ENST00000274565.4
 SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr1_-_55089191 0.031 ENST00000302250.2
ENST00000371304.2
 FAM151A

family with sequence similarity 151, member A

chr3_-_171489085 0.031 ENST00000418087.1
 PLD1
phospholipase D1, phosphatidylcholine-specific
chr21_+_39628655 0.031 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
 KCNJ15



potassium inwardly-rectifying channel, subfamily J, member 15



chr10_+_114135952 0.031 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
 ACSL5


acyl-CoA synthetase long-chain family member 5


chr1_+_39491984 0.031 ENST00000372969.3
ENST00000372967.3
 NDUFS5

NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)

chr8_-_66474884 0.031 ENST00000520902.1
 CTD-3025N20.2
CTD-3025N20.2
chr17_-_73389737 0.031 ENST00000392563.1
 GRB2
growth factor receptor-bound protein 2
chr4_+_159236462 0.031 ENST00000460056.2
 RXFP1
relaxin/insulin-like family peptide receptor 1
chr8_+_95558771 0.030 ENST00000391679.1
 AC023632.1
HCG2009141; PRO2397; Uncharacterized protein
chr10_-_27389392 0.030 ENST00000376087.4
 ANKRD26
ankyrin repeat domain 26

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of interleukin-18 production(GO:0032661)
0.0 0.0 GO:0002877 leukocyte chemotaxis involved in inflammatory response(GO:0002232) acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0075341 host cell PML body(GO:0075341)
0.0 0.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters