Motif ID: OVOL1

Z-value: 0.600


Transcription factors associated with OVOL1:

Gene SymbolEntrez IDGene Name
OVOL1 ENSG00000172818.5 OVOL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
OVOL1hg19_v2_chr11_+_65554493_655545460.373.3e-01Click!


Activity profile for motif OVOL1.

activity profile for motif OVOL1


Sorted Z-values histogram for motif OVOL1

Sorted Z-values for motif OVOL1



Network of associatons between targets according to the STRING database.



First level regulatory network of OVOL1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_165555200 3.008 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
 BCHE



butyrylcholinesterase



chr2_-_183387430 0.632 ENST00000410103.1
 PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387064 0.625 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
 PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr17_-_7145475 0.509 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
 GABARAP


GABA(A) receptor-associated protein


chr2_-_183387283 0.493 ENST00000435564.1
 PDE1A
phosphodiesterase 1A, calmodulin-dependent
chrX_-_117107680 0.415 ENST00000447671.2
ENST00000262820.3
 KLHL13

kelch-like family member 13

chr5_-_16509101 0.407 ENST00000399793.2
 FAM134B
family with sequence similarity 134, member B
chr15_-_64385981 0.381 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
 FAM96A


family with sequence similarity 96, member A


chrX_-_117107542 0.376 ENST00000371878.1
 KLHL13
kelch-like family member 13
chr15_-_64386120 0.357 ENST00000300030.3
 FAM96A
family with sequence similarity 96, member A
chr10_-_21786179 0.221 ENST00000377113.5
 CASC10
cancer susceptibility candidate 10
chr3_-_149093499 0.190 ENST00000472441.1
 TM4SF1
transmembrane 4 L six family member 1
chr1_+_174846570 0.158 ENST00000392064.2
 RABGAP1L
RAB GTPase activating protein 1-like
chr11_+_123301012 0.155 ENST00000533341.1
 AP000783.1
Uncharacterized protein
chr11_+_71710973 0.146 ENST00000393707.4
 IL18BP
interleukin 18 binding protein
chr16_-_67260901 0.139 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
 LRRC29


AC040160.1
leucine rich repeat containing 29


Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr4_+_76481258 0.137 ENST00000311623.4
ENST00000435974.2
 C4orf26

chromosome 4 open reading frame 26

chr15_+_64386261 0.110 ENST00000560829.1
 SNX1
sorting nexin 1
chr5_+_140739537 0.098 ENST00000522605.1
 PCDHGB2
protocadherin gamma subfamily B, 2
chr16_-_67260691 0.087 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
 LRRC29


leucine rich repeat containing 29


chr18_-_10672744 0.075 ENST00000582937.1
 PIEZO2
piezo-type mechanosensitive ion channel component 2
chr4_+_39408470 0.034 ENST00000257408.4
 KLB
klotho beta
chr4_-_68620053 0.031 ENST00000420975.2
ENST00000226413.4
 GNRHR

gonadotropin-releasing hormone receptor

chr5_+_140261703 0.025 ENST00000409494.1
ENST00000289272.2
 PCDHA13

protocadherin alpha 13

chr17_+_67759813 0.022 ENST00000587241.1
 AC003051.1
AC003051.1
chr11_-_6817128 0.006 ENST00000332601.3
 OR6A2
olfactory receptor, family 6, subfamily A, member 2
chr11_-_130786333 0.002 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
 SNX19



sorting nexin 19



chr11_-_75017734 0.000 ENST00000532525.1
 ARRB1
arrestin, beta 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects