Motif ID: OTX1

Z-value: 0.585


Transcription factors associated with OTX1:

Gene SymbolEntrez IDGene Name
OTX1 ENSG00000115507.5 OTX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_63277938-0.284.6e-01Click!


Activity profile for motif OTX1.

activity profile for motif OTX1


Sorted Z-values histogram for motif OTX1

Sorted Z-values for motif OTX1



Network of associatons between targets according to the STRING database.



First level regulatory network of OTX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_36641842 0.689 ENST00000523973.1
ENST00000399881.3
 KCNU1

potassium channel, subfamily U, member 1

chr1_+_196621002 0.623 ENST00000367429.4
ENST00000439155.2
 CFH

complement factor H

chr11_-_85376121 0.527 ENST00000527447.1
 CREBZF
CREB/ATF bZIP transcription factor
chr4_-_112993808 0.474 ENST00000511219.1
 RP11-269F21.3
RP11-269F21.3
chr3_-_52002403 0.392 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
 PCBP4



poly(rC) binding protein 4



chr1_+_229440129 0.382 ENST00000366688.3
 SPHAR
S-phase response (cyclin related)
chr7_-_91509972 0.346 ENST00000425936.1
 MTERF
mitochondrial transcription termination factor
chr6_+_26158343 0.327 ENST00000377777.4
ENST00000289316.2
 HIST1H2BD

histone cluster 1, H2bd

chr15_-_43877062 0.320 ENST00000381885.1
ENST00000396923.3
 PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chr2_+_201936458 0.313 ENST00000237889.4
 NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr1_+_117910047 0.312 ENST00000356554.3
 MAN1A2
mannosidase, alpha, class 1A, member 2
chr1_+_241695424 0.306 ENST00000366558.3
ENST00000366559.4
 KMO

kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

chr19_+_10531150 0.279 ENST00000352831.6
 PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_241695670 0.278 ENST00000366557.4
 KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_+_106546808 0.275 ENST00000369089.3
 PRDM1
PR domain containing 1, with ZNF domain
chr15_+_42787452 0.273 ENST00000249647.3
 SNAP23
synaptosomal-associated protein, 23kDa
chr6_+_26204825 0.271 ENST00000360441.4
 HIST1H4E
histone cluster 1, H4e
chr8_-_56986768 0.271 ENST00000523936.1
 RPS20
ribosomal protein S20
chr15_-_43876702 0.256 ENST00000348806.6
 PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr10_+_67330096 0.251 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
 RP11-222A11.1



RP11-222A11.1



chrX_-_109561294 0.250 ENST00000372059.2
ENST00000262844.5
 AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr4_-_54424366 0.230 ENST00000306888.2
 LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr2_+_201936707 0.229 ENST00000433898.1
ENST00000454214.1
 NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr12_-_71533055 0.222 ENST00000552128.1
 TSPAN8
tetraspanin 8
chr12_+_124997766 0.211 ENST00000543970.1
 RP11-83B20.1
RP11-83B20.1
chr7_-_91509986 0.210 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
 MTERF




mitochondrial transcription termination factor




chr12_+_6603253 0.193 ENST00000382457.4
ENST00000545962.1
 NCAPD2

non-SMC condensin I complex, subunit D2

chr3_-_52002194 0.189 ENST00000466412.1
 PCBP4
poly(rC) binding protein 4
chr2_-_160654745 0.184 ENST00000259053.4
ENST00000429078.2
 CD302

CD302 molecule

chr8_+_101162812 0.181 ENST00000353107.3
ENST00000522439.1
 POLR2K

polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

chr6_-_28806779 0.177 ENST00000457253.1
 XXbac-BPG308K3.5
XXbac-BPG308K3.5
chr2_-_47403642 0.177 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
 CALM2


calmodulin 2 (phosphorylase kinase, delta)


chr13_-_43566301 0.175 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
 EPSTI1


epithelial stromal interaction 1 (breast)


chr12_-_117537240 0.173 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
 TESC


tescalcin


chr18_+_44812072 0.169 ENST00000598649.1
ENST00000586905.2
 CTD-2130O13.1

CTD-2130O13.1

chr6_+_151186554 0.166 ENST00000367321.3
ENST00000367307.4
 MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr5_-_81574160 0.161 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
 RPS23




ribosomal protein S23




chr21_+_18811205 0.160 ENST00000440664.1
 C21orf37
chromosome 21 open reading frame 37
chr19_-_46580352 0.157 ENST00000601672.1
 IGFL4
IGF-like family member 4
chr12_+_100594557 0.157 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
 ACTR6


ARP6 actin-related protein 6 homolog (yeast)


chr5_-_39425222 0.155 ENST00000320816.6
 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr9_-_100935043 0.155 ENST00000343933.5
 CORO2A
coronin, actin binding protein, 2A
chr10_-_104211294 0.151 ENST00000239125.1
 C10orf95
chromosome 10 open reading frame 95
chrX_+_100645812 0.149 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
 RPL36A


RPL36A-HNRNPH2

ribosomal protein L36a


RPL36A-HNRNPH2 readthrough

chr19_+_47616682 0.149 ENST00000594526.1
 SAE1
SUMO1 activating enzyme subunit 1
chr5_-_39425290 0.147 ENST00000545653.1
 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chrX_+_149861836 0.139 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
 MTMR1





myotubularin related protein 1





chr9_+_123884038 0.139 ENST00000373847.1
 CNTRL
centriolin
chr17_-_79623597 0.138 ENST00000574024.1
ENST00000331056.5
 PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr11_-_111957451 0.137 ENST00000504148.2
ENST00000541231.1
 TIMM8B

translocase of inner mitochondrial membrane 8 homolog B (yeast)

chr12_-_107380910 0.137 ENST00000392830.2
ENST00000240050.4
 MTERFD3

MTERF domain containing 3

chr1_-_204116078 0.136 ENST00000367198.2
ENST00000452983.1
 ETNK2

ethanolamine kinase 2

chr22_+_30163340 0.133 ENST00000330029.6
ENST00000401406.3
 UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr3_+_138340049 0.131 ENST00000464668.1
 FAIM
Fas apoptotic inhibitory molecule
chr3_-_141747950 0.130 ENST00000497579.1
 TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_14541060 0.130 ENST00000418420.1
ENST00000417751.1
 LINC00276

long intergenic non-protein coding RNA 276

chr1_-_161039753 0.128 ENST00000368015.1
 ARHGAP30
Rho GTPase activating protein 30
chr12_-_54071181 0.125 ENST00000338662.5
 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr21_+_44073916 0.125 ENST00000349112.3
ENST00000398224.3
 PDE9A

phosphodiesterase 9A

chrX_-_134156502 0.124 ENST00000391440.1
 FAM127C
family with sequence similarity 127, member C
chr2_-_106054952 0.123 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
 FHL2


four and a half LIM domains 2


chr12_-_107380846 0.122 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
 MTERFD3


MTERF domain containing 3


chr3_+_138340067 0.120 ENST00000479848.1
 FAIM
Fas apoptotic inhibitory molecule
chr3_+_142315225 0.119 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1





plastin 1





chr8_-_10512569 0.118 ENST00000382483.3
 RP1L1
retinitis pigmentosa 1-like 1
chr7_+_128379346 0.118 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
 CALU





calumenin





chr4_+_22999152 0.116 ENST00000511453.1
 RP11-412P11.1
RP11-412P11.1
chr6_+_26251835 0.113 ENST00000356350.2
 HIST1H2BH
histone cluster 1, H2bh
chr6_+_35420091 0.113 ENST00000229769.2
 FANCE
Fanconi anemia, complementation group E
chr8_+_109455845 0.113 ENST00000220853.3
 EMC2
ER membrane protein complex subunit 2
chr10_-_116418053 0.112 ENST00000277895.5
 ABLIM1
actin binding LIM protein 1
chr2_-_161350305 0.112 ENST00000348849.3
 RBMS1
RNA binding motif, single stranded interacting protein 1
chr9_+_128509624 0.108 ENST00000342287.5
ENST00000373487.4
 PBX3

pre-B-cell leukemia homeobox 3

chr3_+_145782358 0.107 ENST00000422482.1
 AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr3_-_27410847 0.107 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
 NEK10


NIMA-related kinase 10


chr8_-_74495065 0.106 ENST00000523533.1
 STAU2
staufen double-stranded RNA binding protein 2
chr5_-_77072085 0.104 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
 TBCA



tubulin folding cofactor A



chr1_-_205719295 0.104 ENST00000367142.4
 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_-_154230130 0.104 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
 FAXDC2



fatty acid hydroxylase domain containing 2



chr15_+_92006567 0.100 ENST00000554333.1
 RP11-661P17.1
RP11-661P17.1
chr7_+_128379449 0.098 ENST00000479257.1
 CALU
calumenin
chr2_+_122513109 0.097 ENST00000389682.3
ENST00000536142.1
 TSN

translin

chr17_-_56769382 0.097 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
 TEX14


testis expressed 14


chr4_-_122744998 0.093 ENST00000274026.5
 CCNA2
cyclin A2
chr20_-_32700075 0.093 ENST00000374980.2
 EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr1_+_24882560 0.092 ENST00000374392.2
 NCMAP
noncompact myelin associated protein
chr11_+_130029457 0.091 ENST00000278742.5
 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr14_+_50234309 0.091 ENST00000298307.5
 KLHDC2
kelch domain containing 2
chr11_-_67275542 0.089 ENST00000531506.1
 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr3_-_12587055 0.089 ENST00000564146.3
 C3orf83
chromosome 3 open reading frame 83
chr19_-_16008880 0.088 ENST00000011989.7
ENST00000221700.6
 CYP4F2

cytochrome P450, family 4, subfamily F, polypeptide 2

chr1_-_247335269 0.086 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
 ZNF124



zinc finger protein 124



chr20_-_3140490 0.086 ENST00000449731.1
ENST00000380266.3
 UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr1_-_154928562 0.085 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
 PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr7_+_55980331 0.082 ENST00000429591.2
 ZNF713
zinc finger protein 713
chr5_-_147286065 0.082 ENST00000318315.4
ENST00000515291.1
 C5orf46

chromosome 5 open reading frame 46

chr16_-_8962200 0.082 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
 CARHSP1


calcium regulated heat stable protein 1, 24kDa


chr8_+_109455830 0.081 ENST00000524143.1
 EMC2
ER membrane protein complex subunit 2
chr5_+_80256453 0.078 ENST00000265080.4
 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr1_-_206288647 0.075 ENST00000331555.5
 C1orf186
chromosome 1 open reading frame 186
chr2_+_232135245 0.074 ENST00000446447.1
 ARMC9
armadillo repeat containing 9
chr14_-_89878369 0.074 ENST00000553840.1
ENST00000556916.1
 FOXN3

forkhead box N3

chr13_+_38923959 0.073 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
 UFM1



ubiquitin-fold modifier 1



chr5_-_114631958 0.071 ENST00000395557.4
 CCDC112
coiled-coil domain containing 112
chrM_+_12331 0.071 ENST00000361567.2
 MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr16_-_21452040 0.069 ENST00000521589.1
 NPIPB3
nuclear pore complex interacting protein family, member B3
chr22_+_39052632 0.068 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
 CBY1



chibby homolog 1 (Drosophila)



chr19_+_35940486 0.064 ENST00000246549.2
 FFAR2
free fatty acid receptor 2
chr6_-_144416737 0.063 ENST00000367569.2
 SF3B5
splicing factor 3b, subunit 5, 10kDa
chr6_+_150070857 0.063 ENST00000544496.1
 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr8_-_79717750 0.063 ENST00000263851.4
ENST00000379113.2
 IL7

interleukin 7

chr3_-_69062764 0.062 ENST00000295571.5
 EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr12_+_20963632 0.062 ENST00000540853.1
ENST00000261196.2
 SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr21_+_17214724 0.061 ENST00000449491.1
 USP25
ubiquitin specific peptidase 25
chr20_-_33539655 0.061 ENST00000451957.2
 GSS
glutathione synthetase
chr1_-_9811600 0.060 ENST00000435891.1
 CLSTN1
calsyntenin 1
chr8_-_110988070 0.060 ENST00000524391.1
 KCNV1
potassium channel, subfamily V, member 1
chrX_-_100307043 0.059 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
 TRMT2B


tRNA methyltransferase 2 homolog B (S. cerevisiae)


chr1_+_170501270 0.058 ENST00000367763.3
ENST00000367762.1
 GORAB

golgin, RAB6-interacting

chr1_+_17531614 0.057 ENST00000375471.4
 PADI1
peptidyl arginine deiminase, type I
chr5_+_135496675 0.056 ENST00000507637.1
 SMAD5
SMAD family member 5
chr12_+_20963647 0.056 ENST00000381545.3
 SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_+_83956312 0.055 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
 COPS4


COP9 signalosome subunit 4


chr4_-_184241927 0.055 ENST00000323319.5
 CLDN22
claudin 22
chr6_+_96025341 0.055 ENST00000369293.1
ENST00000358812.4
 MANEA

mannosidase, endo-alpha

chr5_-_59783882 0.055 ENST00000505507.2
ENST00000502484.2
 PDE4D

phosphodiesterase 4D, cAMP-specific

chr3_-_156878540 0.055 ENST00000461804.1
 CCNL1
cyclin L1
chr7_+_16700806 0.052 ENST00000446596.1
ENST00000438834.1
 BZW2

basic leucine zipper and W2 domains 2

chr19_-_36001286 0.051 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
 DMKN














dermokine














chr21_-_43816052 0.047 ENST00000398405.1
 TMPRSS3
transmembrane protease, serine 3
chr3_-_138763734 0.046 ENST00000413199.1
ENST00000502927.2
 PRR23C

proline rich 23C

chr2_-_74619152 0.045 ENST00000440727.1
ENST00000409240.1
 DCTN1

dynactin 1

chr13_+_24825824 0.045 ENST00000434675.1
ENST00000494772.1
 SPATA13

spermatogenesis associated 13

chr4_+_83956237 0.043 ENST00000264389.2
 COPS4
COP9 signalosome subunit 4
chr6_-_34393825 0.042 ENST00000326199.8
ENST00000605528.1
 RPS10
RPS10-NUDT3
ribosomal protein S10
RPS10-NUDT3 readthrough
chr14_-_102552659 0.042 ENST00000441629.2
 HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_-_160924589 0.042 ENST00000368029.3
 ITLN2
intelectin 2
chr9_+_67968793 0.041 ENST00000417488.1
 RP11-195B21.3
Protein LOC644249
chr3_+_42544084 0.040 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
 VIPR1



vasoactive intestinal peptide receptor 1



chr3_+_142315294 0.039 ENST00000464320.1
 PLS1
plastin 1
chr11_-_102962874 0.038 ENST00000531543.1
 DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr11_-_8959758 0.038 ENST00000531618.1
 ASCL3
achaete-scute family bHLH transcription factor 3
chr15_+_58702742 0.038 ENST00000356113.6
ENST00000414170.3
 LIPC

lipase, hepatic

chr19_-_36001386 0.035 ENST00000461300.1
 DMKN
dermokine
chr1_-_89458604 0.034 ENST00000260508.4
 CCBL2
cysteine conjugate-beta lyase 2
chr15_-_55657428 0.033 ENST00000568543.1
 CCPG1
cell cycle progression 1
chr2_-_112642267 0.033 ENST00000341068.3
 ANAPC1
anaphase promoting complex subunit 1
chr5_+_59783941 0.033 ENST00000506884.1
ENST00000504876.2
 PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr2_-_74618964 0.033 ENST00000417090.1
ENST00000409868.1
 DCTN1

dynactin 1

chr9_-_35665165 0.033 ENST00000343259.3
ENST00000378387.3
 ARHGEF39

Rho guanine nucleotide exchange factor (GEF) 39

chr19_-_12941215 0.031 ENST00000458671.2
 RTBDN
retbindin
chr3_-_69129501 0.031 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
 UBA3



ubiquitin-like modifier activating enzyme 3



chr7_-_120498357 0.031 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
 TSPAN12


tetraspanin 12


chr1_+_92417716 0.030 ENST00000402388.1
 BRDT
bromodomain, testis-specific
chr3_+_121311966 0.029 ENST00000338040.4
 FBXO40
F-box protein 40
chr22_-_36903101 0.028 ENST00000397224.4
 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr3_+_188664988 0.028 ENST00000433971.1
 TPRG1
tumor protein p63 regulated 1
chr3_+_58223228 0.028 ENST00000478253.1
ENST00000295962.4
 ABHD6

abhydrolase domain containing 6

chr14_+_21458127 0.026 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
 METTL17





methyltransferase like 17





chr9_-_35563896 0.026 ENST00000399742.2
 FAM166B
family with sequence similarity 166, member B
chr6_+_33359582 0.025 ENST00000450504.1
 KIFC1
kinesin family member C1
chr10_+_114133773 0.025 ENST00000354655.4
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_-_58163299 0.023 ENST00000262498.3
 C16orf80
chromosome 16 open reading frame 80
chr10_-_50122277 0.022 ENST00000374160.3
 LRRC18
leucine rich repeat containing 18
chr7_+_134916731 0.021 ENST00000275764.3
 STRA8
stimulated by retinoic acid 8
chr3_+_195447738 0.021 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
 MUC20


mucin 20, cell surface associated


chr1_-_53608249 0.021 ENST00000371494.4
 SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr1_-_166944561 0.021 ENST00000271417.3
 ILDR2
immunoglobulin-like domain containing receptor 2
chr22_-_30162924 0.021 ENST00000344318.3
ENST00000397781.3
 ZMAT5

zinc finger, matrin-type 5

chr14_-_107131560 0.020 ENST00000390632.2
 IGHV3-66
immunoglobulin heavy variable 3-66
chr19_-_36001113 0.019 ENST00000434389.1
 DMKN
dermokine
chrX_-_138072729 0.018 ENST00000455663.1
 FGF13
fibroblast growth factor 13
chr14_-_106471723 0.018 ENST00000390595.2
 IGHV1-3
immunoglobulin heavy variable 1-3
chr20_+_9146969 0.018 ENST00000416836.1
 PLCB4
phospholipase C, beta 4
chr17_-_34592032 0.017 ENST00000457979.3
 TBC1D3C
TBC1 domain family, member 3C
chr13_+_57741718 0.017 ENST00000445351.1
 PRR20E
proline rich 20E
chr1_+_3668962 0.017 ENST00000294600.2
 CCDC27
coiled-coil domain containing 27
chr2_-_234475380 0.017 ENST00000443711.2
ENST00000251722.6
 USP40

ubiquitin specific peptidase 40

chr19_+_55084438 0.016 ENST00000439534.1
 LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr14_-_107211459 0.016 ENST00000390636.2
 IGHV3-73
immunoglobulin heavy variable 3-73
chr1_+_221054411 0.016 ENST00000427693.1
 HLX
H2.0-like homeobox
chr5_+_177631497 0.015 ENST00000358344.3
 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr14_+_102196739 0.014 ENST00000556973.1
 RP11-796G6.2
Uncharacterized protein
chr14_-_80697396 0.014 ENST00000557010.1
 DIO2
deiodinase, iodothyronine, type II
chr16_-_29875057 0.014 ENST00000219789.6
 CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr4_-_83769996 0.013 ENST00000511338.1
 SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_+_183815318 0.012 ENST00000425359.2
 HTR3E
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
chr2_-_61389168 0.012 ENST00000607743.1
ENST00000605902.1
 RP11-493E12.1

RP11-493E12.1

chr15_+_75550940 0.012 ENST00000300576.5
 GOLGA6C
golgin A6 family, member C
chr12_+_108523133 0.012 ENST00000547525.1
 WSCD2
WSC domain containing 2
chr19_+_41903709 0.012 ENST00000542943.1
ENST00000457836.2
 BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr10_-_10836919 0.012 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
 SFTA1P


surfactant associated 1, pseudogene


chr12_-_4754318 0.012 ENST00000536414.1
 AKAP3
A kinase (PRKA) anchor protein 3
chrX_+_2670153 0.011 ENST00000509484.2
 XG
Xg blood group
chr3_-_69062790 0.011 ENST00000540955.1
ENST00000456376.1
 EOGT

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

chr1_+_87458692 0.011 ENST00000356813.4
ENST00000370548.2
 HS2ST1
RP5-1052I5.2
heparan sulfate 2-O-sulfotransferase 1
Heparan sulfate 2-O-sulfotransferase 1
chr10_-_115423792 0.010 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
 NRAP



nebulin-related anchoring protein



chr1_+_160709076 0.010 ENST00000359331.4
ENST00000495334.1
 SLAMF7

SLAM family member 7

chr16_-_69373396 0.010 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
 COG8


component of oligomeric golgi complex 8


chr5_-_142023766 0.008 ENST00000394496.2
 FGF1
fibroblast growth factor 1 (acidic)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0032304 pressure natriuresis(GO:0003095) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0002877 leukocyte chemotaxis involved in inflammatory response(GO:0002232) acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0 0.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0052870 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation