Motif ID: OLIG2_NEUROD1_ATOH1

Z-value: 0.906

Transcription factors associated with OLIG2_NEUROD1_ATOH1:

Gene SymbolEntrez IDGene Name
ATOH1 ENSG00000172238.3 ATOH1
NEUROD1 ENSG00000162992.3 NEUROD1
OLIG2 ENSG00000205927.4 OLIG2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
OLIG2hg19_v2_chr21_+_34398153_343982500.274.8e-01Click!
NEUROD1hg19_v2_chr2_-_182545603_182545603-0.009.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_52486841 1.202 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr2_-_183387430 1.083 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387064 1.066 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr4_-_186877502 1.029 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr2_+_196440692 0.956 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_-_183387283 0.942 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_154335300 0.900 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr11_+_46299199 0.878 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr9_-_131644202 0.819 ENST00000320665.6
ENST00000436267.2
CCBL1

cysteine conjugate-beta lyase, cytoplasmic

chr10_+_18429671 0.814 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_54157480 0.774 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr10_+_18429606 0.715 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2


calcium channel, voltage-dependent, beta 2 subunit


chr2_-_163100045 0.692 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr9_-_131644306 0.690 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr2_+_233385173 0.671 ENST00000449534.2
PRSS56
protease, serine, 56
chr10_-_105437909 0.649 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr12_-_68845417 0.618 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr7_-_75401513 0.609 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr11_+_7597639 0.568 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_+_135278908 0.567 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chr5_+_139055021 0.541 ENST00000502716.1
ENST00000503511.1
CXXC5

CXXC finger protein 5

chr4_-_186733363 0.519 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr16_-_30107491 0.513 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr1_-_74663825 0.500 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3


leucine-rich repeats and IQ motif containing 3


chr11_+_57365150 0.497 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr15_-_96590126 0.497 ENST00000561051.1
RP11-4G2.1
RP11-4G2.1
chr8_+_81397876 0.491 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr4_-_186877806 0.484 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186877481 0.482 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr2_+_29001711 0.480 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr19_-_46285646 0.477 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr19_-_46285736 0.456 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chrX_-_13835461 0.444 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr3_+_99833755 0.442 ENST00000489081.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chr7_+_75931861 0.438 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr8_-_49834299 0.437 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_+_139055055 0.437 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr5_-_180632147 0.436 ENST00000274773.7
TRIM7
tripartite motif containing 7
chr8_-_49833978 0.431 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr11_-_66675371 0.431 ENST00000393955.2
PC
pyruvate carboxylase
chrX_-_13835147 0.430 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr5_+_135364584 0.413 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr1_+_19967014 0.407 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr7_-_99869799 0.400 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr17_-_37009882 0.397 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23




ribosomal protein L23




chr5_-_111312622 0.395 ENST00000395634.3
NREP
neuronal regeneration related protein
chr3_-_178789220 0.385 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr5_-_180632293 0.381 ENST00000334421.5
TRIM7
tripartite motif containing 7
chr4_-_186732892 0.379 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr8_+_70378852 0.373 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr8_-_128231299 0.372 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr22_-_42342692 0.372 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chr17_+_74723031 0.370 ENST00000586200.1
METTL23
methyltransferase like 23
chr19_-_18391708 0.368 ENST00000600972.1
JUND
jun D proto-oncogene
chr19_-_11450249 0.363 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr6_+_30851840 0.362 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1





discoidin domain receptor tyrosine kinase 1





chr15_+_75940218 0.356 ENST00000308527.5
SNX33
sorting nexin 33
chr15_-_75660919 0.353 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1






mannosidase, alpha, class 2C, member 1






chr10_-_69597915 0.351 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr14_+_24584508 0.350 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr10_-_69597810 0.345 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr9_+_131683174 0.345 ENST00000372592.3
ENST00000428610.1
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr10_+_102759545 0.330 ENST00000454422.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr8_+_81398444 0.327 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr15_+_49715293 0.325 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr19_-_6720686 0.323 ENST00000245907.6
C3
complement component 3
chr9_+_72658490 0.323 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr7_-_150777920 0.318 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr15_+_49715449 0.318 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr7_+_30174426 0.312 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr11_-_63933504 0.309 ENST00000255681.6
MACROD1
MACRO domain containing 1
chr2_+_85661918 0.307 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr8_+_81397846 0.300 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr6_-_66417107 0.299 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr17_+_74722912 0.292 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23










methyltransferase like 23










chr7_-_150777949 0.289 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr11_-_14913765 0.286 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr8_-_135522425 0.285 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chrX_+_135279179 0.280 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr11_-_14913190 0.278 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr6_-_112194484 0.278 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN






FYN oncogene related to SRC, FGR, YES






chr17_+_7792101 0.271 ENST00000358181.4
ENST00000330494.7
CHD3

chromodomain helicase DNA binding protein 3

chr2_-_220083076 0.271 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_+_155090271 0.270 ENST00000476756.1
INSIG1
insulin induced gene 1
chr3_-_178790057 0.269 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr1_-_209792111 0.260 ENST00000455193.1
LAMB3
laminin, beta 3
chr10_-_97321112 0.257 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1







sorbin and SH3 domain containing 1







chr11_-_94965667 0.256 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chr10_-_69597828 0.255 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr10_+_102759045 0.255 ENST00000370220.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr19_-_4454081 0.254 ENST00000591919.1
UBXN6
UBX domain protein 6
chr12_+_56473628 0.253 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr9_+_131174024 0.253 ENST00000420034.1
ENST00000372842.1
CERCAM

cerebral endothelial cell adhesion molecule

chr11_+_20044096 0.252 ENST00000533917.1
NAV2
neuron navigator 2
chr1_-_84464780 0.252 ENST00000260505.8
TTLL7
tubulin tyrosine ligase-like family, member 7
chr9_+_19408999 0.248 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr10_-_72141330 0.245 ENST00000395011.1
ENST00000395010.1
LRRC20

leucine rich repeat containing 20

chr5_+_38258511 0.244 ENST00000354891.3
ENST00000322350.5
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr19_+_39687596 0.242 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr1_+_12524965 0.241 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr3_+_49058444 0.238 ENST00000326925.6
ENST00000395458.2
NDUFAF3

NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

chr7_-_97881429 0.236 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1




tectonin beta-propeller repeat containing 1




chr2_-_2334888 0.236 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr17_+_67498295 0.233 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr7_+_30174574 0.231 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_1795012 0.231 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3



fibroblast growth factor receptor 3



chr11_-_1587166 0.229 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr1_+_74663896 0.228 ENST00000370891.2
ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
TNNI3K
FPGT





FPGT-TNNI3K




TNNI3 interacting kinase
fucose-1-phosphate guanylyltransferase





FPGT-TNNI3K readthrough




chr11_-_83984231 0.227 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
DLG2




discs, large homolog 2 (Drosophila)




chr2_+_95963052 0.227 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr11_+_1049862 0.226 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr7_-_150777874 0.217 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr17_+_67498538 0.215 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr15_-_63448973 0.214 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr7_+_114055052 0.211 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr12_+_6309963 0.207 ENST00000382515.2
CD9
CD9 molecule
chr17_-_45918539 0.206 ENST00000584123.1
ENST00000578323.1
ENST00000407215.3
ENST00000290216.9
SCRN2



secernin 2



chr1_-_153363452 0.206 ENST00000368732.1
ENST00000368733.3
S100A8

S100 calcium binding protein A8

chr1_-_205391178 0.204 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr11_-_119252359 0.201 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr4_+_53525573 0.201 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chrX_+_150565038 0.201 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr1_-_150849208 0.200 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr9_+_12775011 0.199 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr7_-_150780487 0.197 ENST00000482202.1
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr1_+_6508100 0.197 ENST00000461727.1
ESPN
espin
chr11_+_66115304 0.195 ENST00000531602.1
RP11-867G23.8
Uncharacterized protein
chr9_-_33447584 0.194 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr6_+_136172820 0.193 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr19_-_46272106 0.193 ENST00000560168.1
SIX5
SIX homeobox 5
chr5_+_102201430 0.193 ENST00000438793.3
ENST00000346918.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr22_-_21905120 0.191 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr12_-_13105081 0.187 ENST00000541128.1
GPRC5D
G protein-coupled receptor, family C, group 5, member D
chr17_+_67498396 0.185 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_+_64004888 0.185 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr5_+_66124590 0.182 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr17_+_7341586 0.178 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr18_+_43914159 0.175 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165


ring finger protein 165


chr12_-_109027643 0.172 ENST00000388962.3
ENST00000550948.1
SELPLG

selectin P ligand

chr13_-_101327028 0.172 ENST00000328767.5
ENST00000342624.5
ENST00000376234.3
ENST00000423847.1
TMTC4



transmembrane and tetratricopeptide repeat containing 4



chr12_+_6309517 0.172 ENST00000382519.4
ENST00000009180.4
CD9

CD9 molecule

chr8_+_70379072 0.168 ENST00000529134.1
SULF1
sulfatase 1
chr12_-_7245125 0.167 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr9_+_129622904 0.164 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr12_-_7245080 0.164 ENST00000541042.1
ENST00000540242.1
C1R

complement component 1, r subcomponent

chr6_-_26250835 0.164 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr3_-_71774516 0.163 ENST00000425534.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr3_+_111630451 0.163 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr11_-_695162 0.162 ENST00000338675.6
DEAF1
DEAF1 transcription factor
chr1_+_12538594 0.162 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr6_+_30852130 0.160 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1



discoidin domain receptor tyrosine kinase 1



chr9_+_19408919 0.160 ENST00000380376.1
ACER2
alkaline ceramidase 2
chr1_+_223101757 0.160 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr10_-_61513201 0.159 ENST00000414264.1
ENST00000594536.1
LINC00948

long intergenic non-protein coding RNA 948

chr2_+_120187465 0.159 ENST00000409826.1
ENST00000417645.1
TMEM37

transmembrane protein 37

chr12_+_54393880 0.155 ENST00000303450.4
HOXC9
homeobox C9
chrX_-_134049262 0.153 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr5_+_102201509 0.153 ENST00000348126.2
ENST00000379787.4
PAM

peptidylglycine alpha-amidating monooxygenase

chr19_+_1241732 0.153 ENST00000215375.2
ENST00000395633.1
ENST00000591660.1
ATP5D


ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit


chr5_+_102201722 0.153 ENST00000274392.9
ENST00000455264.2
PAM

peptidylglycine alpha-amidating monooxygenase

chr5_-_59481406 0.152 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_5229819 0.151 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WIPI2


WD repeat domain, phosphoinositide interacting 2


chr5_+_102201687 0.148 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr4_-_186733119 0.147 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr15_+_75118888 0.146 ENST00000395018.4
CPLX3
complexin 3
chr12_+_116997186 0.146 ENST00000306985.4
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr7_-_86848933 0.144 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr7_-_44105158 0.144 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr17_-_79166176 0.143 ENST00000571292.1
AZI1
5-azacytidine induced 1
chr8_-_66701319 0.143 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr6_-_110736742 0.142 ENST00000368924.3
ENST00000368923.3
DDO

D-aspartate oxidase

chr11_+_32112431 0.142 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chrX_+_54835493 0.141 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr19_-_44008863 0.139 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr17_-_77813186 0.139 ENST00000448310.1
ENST00000269397.4
CBX4

chromobox homolog 4

chr12_-_7245018 0.138 ENST00000543835.1
ENST00000535233.2
C1R

complement component 1, r subcomponent

chr15_+_57511609 0.136 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12


transcription factor 12


chr2_-_132589601 0.136 ENST00000437330.1
AC103564.7
AC103564.7
chr19_-_19030157 0.135 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
COPE



coatomer protein complex, subunit epsilon



chrX_-_63005405 0.135 ENST00000374878.1
ENST00000437457.2
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr3_+_164924716 0.134 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr1_+_228337553 0.133 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chrX_+_67913471 0.133 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr4_+_88343952 0.131 ENST00000440591.2
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr5_-_36241900 0.131 ENST00000381937.4
ENST00000514504.1
NADK2

NAD kinase 2, mitochondrial

chr16_+_23847267 0.128 ENST00000321728.7
PRKCB
protein kinase C, beta
chr6_+_30856507 0.128 ENST00000513240.1
ENST00000424544.2
DDR1

discoidin domain receptor tyrosine kinase 1

chr11_+_827553 0.128 ENST00000528542.2
ENST00000450448.1
EFCAB4A

EF-hand calcium binding domain 4A

chr10_+_102758105 0.128 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr11_-_57417405 0.127 ENST00000524669.1
ENST00000300022.3
YPEL4

yippee-like 4 (Drosophila)

chr17_-_15168624 0.126 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22


peripheral myelin protein 22


chr2_-_42160486 0.126 ENST00000427054.1
AC104654.2
AC104654.2
chrX_-_134049233 0.126 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr7_+_30174668 0.125 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr9_+_2017063 0.125 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_-_131623043 0.123 ENST00000421707.1
MBNL3
muscleblind-like splicing regulator 3
chr16_+_19222479 0.122 ENST00000568433.1
SYT17
synaptotagmin XVII
chr8_+_70476088 0.122 ENST00000525999.1
SULF1
sulfatase 1
chr6_+_30852738 0.121 ENST00000508312.1
ENST00000512336.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr4_+_8201091 0.120 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.7 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 1.0 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 1.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.5 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 3.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 3.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.4 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.0 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 0.8 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 1.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.6 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 1.3 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones