Motif ID: NR1I2

Z-value: 0.359


Transcription factors associated with NR1I2:

Gene SymbolEntrez IDGene Name
NR1I2 ENSG00000144852.12 NR1I2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_1194993310.481.9e-01Click!


Activity profile for motif NR1I2.

activity profile for motif NR1I2


Sorted Z-values histogram for motif NR1I2

Sorted Z-values for motif NR1I2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1I2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_66624527 0.562 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr7_+_22766766 0.367 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr11_-_63330842 0.363 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chrX_-_15619076 0.231 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr17_-_4852332 0.225 ENST00000572383.1
PFN1
profilin 1
chr16_-_28937027 0.224 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr1_+_15479054 0.215 ENST00000376014.3
ENST00000451326.2
TMEM51

transmembrane protein 51

chr3_+_133524459 0.210 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chr15_+_59903975 0.208 ENST00000560585.1
ENST00000396065.1
GCNT3

glucosaminyl (N-acetyl) transferase 3, mucin type

chr16_+_691792 0.206 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr16_+_84209738 0.196 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr15_+_39873268 0.195 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr5_+_139055021 0.191 ENST00000502716.1
ENST00000503511.1
CXXC5

CXXC finger protein 5

chr13_+_49551020 0.171 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr19_+_39616410 0.171 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr12_-_52685312 0.168 ENST00000327741.5
KRT81
keratin 81
chr12_-_15104040 0.161 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr16_+_1832902 0.158 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2





nucleotide binding protein 2





chr16_+_83986827 0.155 ENST00000393306.1
ENST00000565123.1
OSGIN1

oxidative stress induced growth inhibitor 1

chr5_+_73109339 0.151 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr19_+_1248547 0.150 ENST00000586757.1
ENST00000300952.2
MIDN

midnolin

chr1_+_223101757 0.149 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr11_-_407103 0.148 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr16_-_48644061 0.147 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr10_+_81065975 0.142 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr11_-_67141640 0.142 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr16_+_28874345 0.140 ENST00000566209.1
SH2B1
SH2B adaptor protein 1
chr7_-_100183742 0.140 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr1_+_35247859 0.135 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr16_-_28936493 0.134 ENST00000544477.1
ENST00000357573.6
RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr7_+_143080063 0.133 ENST00000446634.1
ZYX
zyxin
chr10_+_112257596 0.132 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr11_+_62439126 0.129 ENST00000377953.3
C11orf83
chromosome 11 open reading frame 83
chr7_-_149158187 0.128 ENST00000247930.4
ZNF777
zinc finger protein 777
chr4_+_75174204 0.126 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr1_+_15479021 0.123 ENST00000428417.1
TMEM51
transmembrane protein 51
chr8_+_99956662 0.122 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2


odd-skipped related transciption factor 2


chr1_+_149858461 0.122 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr16_-_2770216 0.121 ENST00000302641.3
PRSS27
protease, serine 27
chr5_+_139055055 0.121 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr3_+_11267691 0.117 ENST00000413416.1
HRH1
histamine receptor H1
chr5_+_177027101 0.117 ENST00000029410.5
ENST00000510761.1
ENST00000505468.1
B4GALT7


xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7


chr2_-_158732340 0.115 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chr17_+_38497640 0.115 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr6_+_106988986 0.114 ENST00000457437.1
ENST00000535438.1
AIM1

absent in melanoma 1

chr1_-_149814478 0.113 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_-_153521714 0.111 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr10_-_125853200 0.110 ENST00000421115.1
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr16_+_30710462 0.109 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP


Snf2-related CREBBP activator protein


chr1_+_36621174 0.108 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr1_+_11796177 0.108 ENST00000400895.2
ENST00000376629.4
ENST00000376627.2
ENST00000314340.5
ENST00000452018.2
ENST00000510878.1
AGTRAP





angiotensin II receptor-associated protein





chr19_-_3547305 0.106 ENST00000589063.1
MFSD12
major facilitator superfamily domain containing 12
chr19_-_51289374 0.106 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr9_-_129885010 0.104 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr19_+_40697514 0.103 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr17_-_49198216 0.102 ENST00000262013.7
ENST00000357122.4
SPAG9

sperm associated antigen 9

chr16_+_28874860 0.102 ENST00000545570.1
SH2B1
SH2B adaptor protein 1
chr10_+_81107271 0.102 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chrX_+_16668278 0.099 ENST00000380200.3
S100G
S100 calcium binding protein G
chr16_+_619931 0.099 ENST00000321878.5
ENST00000439574.1
ENST00000026218.5
ENST00000470411.2
PIGQ



phosphatidylinositol glycan anchor biosynthesis, class Q



chr16_+_29991673 0.099 ENST00000416441.2
TAOK2
TAO kinase 2
chr11_+_63993738 0.098 ENST00000441250.2
ENST00000279206.3
NUDT22

nudix (nucleoside diphosphate linked moiety X)-type motif 22

chr12_-_94673956 0.097 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr19_+_1438351 0.096 ENST00000233609.4
RPS15
ribosomal protein S15
chr8_+_39972170 0.093 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr1_+_199996702 0.093 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_-_89746264 0.093 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr12_+_52626898 0.092 ENST00000331817.5
KRT7
keratin 7
chr16_-_4466565 0.092 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7


CORO7-PAM16 readthrough
coronin 7


chr15_+_92397051 0.091 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr17_-_41623691 0.091 ENST00000545954.1
ETV4
ets variant 4
chr9_-_129884902 0.090 ENST00000373417.1
ANGPTL2
angiopoietin-like 2
chrX_+_152990302 0.090 ENST00000218104.3
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr11_+_67798363 0.090 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr7_-_131241361 0.089 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr1_+_218519577 0.089 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chr19_-_10946949 0.088 ENST00000214869.2
ENST00000591695.1
TMED1

transmembrane emp24 protein transport domain containing 1

chr3_-_4927447 0.086 ENST00000449914.1
AC018816.3
Uncharacterized protein
chr8_+_99956759 0.085 ENST00000522510.1
ENST00000457907.2
OSR2

odd-skipped related transciption factor 2

chr20_-_3748416 0.085 ENST00000399672.1
C20orf27
chromosome 20 open reading frame 27
chr1_+_11796126 0.084 ENST00000376637.3
AGTRAP
angiotensin II receptor-associated protein
chr12_-_49582978 0.084 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr11_+_65687158 0.083 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr17_-_73761222 0.083 ENST00000437911.1
ENST00000225614.2
GALK1

galactokinase 1

chr5_-_73937244 0.083 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1


ectodermal-neural cortex 1 (with BTB domain)


chr17_-_2615031 0.082 ENST00000576885.1
ENST00000574426.2
CLUH

clustered mitochondria (cluA/CLU1) homolog

chr19_+_4153598 0.081 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3




cAMP responsive element binding protein 3-like 3




chr6_+_144980954 0.081 ENST00000367525.3
UTRN
utrophin
chr17_+_43239231 0.080 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2


hexamethylene bis-acetamide inducible 2


chr19_-_38806560 0.080 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr1_-_157108130 0.079 ENST00000368192.4
ETV3
ets variant 3
chr17_-_2614927 0.079 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr19_-_38806390 0.078 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr5_-_1801408 0.078 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr16_+_67563250 0.077 ENST00000566907.1
FAM65A
family with sequence similarity 65, member A
chr20_+_62492566 0.077 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr19_-_38806540 0.077 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr7_-_150777920 0.076 ENST00000353841.2
ENST00000297532.6
FASTK

Fas-activated serine/threonine kinase

chr2_+_10560147 0.076 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr1_-_157108266 0.076 ENST00000326786.4
ETV3
ets variant 3
chr5_-_149682447 0.076 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr17_-_41623716 0.076 ENST00000319349.5
ETV4
ets variant 4
chr7_-_150777949 0.076 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr12_-_52585765 0.075 ENST00000313234.5
ENST00000394815.2
KRT80

keratin 80

chr12_-_122238464 0.075 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr10_+_80828774 0.074 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr6_-_154751629 0.073 ENST00000424998.1
CNKSR3
CNKSR family member 3
chr6_+_31515337 0.073 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr6_+_43457317 0.071 ENST00000438588.2
TJAP1
tight junction associated protein 1 (peripheral)
chr9_-_4299874 0.070 ENST00000381971.3
ENST00000477901.1
GLIS3

GLIS family zinc finger 3

chr15_+_96876340 0.070 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr22_+_45098067 0.070 ENST00000336985.6
ENST00000403696.1
ENST00000457960.1
ENST00000361473.5
PRR5


PRR5-ARHGAP8
proline rich 5 (renal)


PRR5-ARHGAP8 readthrough
chr12_-_124873357 0.069 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr10_+_69865866 0.069 ENST00000354393.2
MYPN
myopalladin
chr5_+_66124590 0.068 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr6_-_42110342 0.068 ENST00000356542.5
C6orf132
chromosome 6 open reading frame 132
chr2_-_43266680 0.067 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2


AC016735.2


chr14_-_65769392 0.066 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr22_-_43567750 0.064 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr1_+_43291220 0.064 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_+_12007963 0.064 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr3_-_196065248 0.063 ENST00000446879.1
ENST00000273695.3
TM4SF19

transmembrane 4 L six family member 19

chr3_+_193853927 0.063 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr5_+_92919043 0.063 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_-_72414256 0.063 ENST00000427971.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_+_115983808 0.063 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr16_+_30675654 0.063 ENST00000287468.5
ENST00000395073.2
FBRS

fibrosin

chr19_+_41117770 0.062 ENST00000601032.1
LTBP4
latent transforming growth factor beta binding protein 4
chr1_+_151739131 0.061 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr12_-_95510743 0.061 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr8_+_86999516 0.061 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr9_-_14314066 0.060 ENST00000397575.3
NFIB
nuclear factor I/B
chr1_+_110754094 0.060 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4


potassium voltage-gated channel, Shaw-related subfamily, member 4


chr16_+_28875126 0.060 ENST00000359285.5
ENST00000538342.1
SH2B1

SH2B adaptor protein 1

chr11_+_86502085 0.059 ENST00000527521.1
PRSS23
protease, serine, 23
chr19_+_45394477 0.059 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr1_+_74701062 0.055 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr22_+_30821784 0.055 ENST00000407550.3
MTFP1
mitochondrial fission process 1
chr22_+_50354104 0.054 ENST00000360612.4
PIM3
pim-3 oncogene
chr1_-_211752073 0.054 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr1_-_229569834 0.054 ENST00000366684.3
ENST00000366683.2
ACTA1

actin, alpha 1, skeletal muscle

chr19_+_1438383 0.053 ENST00000586686.2
ENST00000591032.1
ENST00000586656.1
ENST00000589656.2
ENST00000593052.1
ENST00000586096.2
ENST00000591804.2
RPS15






ribosomal protein S15






chr7_-_150777874 0.053 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr9_-_34048873 0.052 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr20_-_44485835 0.052 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8


acyl-CoA thioesterase 8


chr15_-_65067773 0.052 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr17_-_4852243 0.051 ENST00000225655.5
PFN1
profilin 1
chr9_-_130966497 0.051 ENST00000393608.1
ENST00000372948.3
CIZ1

CDKN1A interacting zinc finger protein 1

chr3_-_185826286 0.050 ENST00000537818.1
ENST00000422039.1
ENST00000434744.1
ETV5


ets variant 5


chr6_-_152623231 0.049 ENST00000540663.1
ENST00000537033.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr1_-_173886491 0.049 ENST00000367698.3
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr11_-_1782625 0.048 ENST00000438213.1
CTSD
cathepsin D
chr1_-_186430222 0.047 ENST00000391997.2
PDC
phosducin
chr13_-_110959478 0.046 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr6_+_126102292 0.046 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chrX_-_48216101 0.046 ENST00000298396.2
ENST00000376893.3
SSX3

synovial sarcoma, X breakpoint 3

chr19_+_35485682 0.046 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr3_+_137906109 0.046 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8



armadillo repeat containing 8



chr1_+_199996733 0.046 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_+_57854274 0.045 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr19_-_51289436 0.045 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr6_-_138893661 0.045 ENST00000427025.2
NHSL1
NHS-like 1
chr17_+_12453278 0.044 ENST00000577679.1
LINC00670
long intergenic non-protein coding RNA 670
chr16_-_15950868 0.044 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11



myosin, heavy chain 11, smooth muscle



chr13_+_24844979 0.044 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr11_-_124180733 0.043 ENST00000357821.2
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr16_-_68002456 0.043 ENST00000576616.1
ENST00000572037.1
ENST00000338335.3
ENST00000422611.2
ENST00000316341.3
SLC12A4




solute carrier family 12 (potassium/chloride transporter), member 4




chr18_+_61442629 0.043 ENST00000398019.2
ENST00000540675.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr4_+_77356248 0.043 ENST00000296043.6
SHROOM3
shroom family member 3
chr13_+_24844857 0.043 ENST00000409126.1
ENST00000343003.6
SPATA13

spermatogenesis associated 13

chr12_+_34175398 0.042 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr14_+_23340822 0.042 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr12_+_6494285 0.042 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr3_-_114790179 0.042 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr9_-_96215822 0.042 ENST00000375412.5
FAM120AOS
family with sequence similarity 120A opposite strand
chr10_-_125851961 0.041 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr3_+_69985792 0.041 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr3_+_69985734 0.041 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr3_+_37284824 0.041 ENST00000431105.1
GOLGA4
golgin A4
chr10_-_21186144 0.041 ENST00000377119.1
NEBL
nebulette
chr6_-_31864977 0.041 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr9_-_140115775 0.040 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr19_+_16187816 0.040 ENST00000588410.1
TPM4
tropomyosin 4
chr4_+_30721968 0.040 ENST00000361762.2
PCDH7
protocadherin 7
chr10_-_105677427 0.039 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr3_+_183817967 0.039 ENST00000335304.2
ENST00000431041.1
ENST00000436361.2
ENST00000440596.2
HTR3E



5-hydroxytryptamine (serotonin) receptor 3E, ionotropic



chr11_+_62648357 0.039 ENST00000541372.1
ENST00000539458.1
SLC3A2

solute carrier family 3 (amino acid transporter heavy chain), member 2

chr3_-_196065374 0.039 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr20_+_3776371 0.038 ENST00000245960.5
CDC25B
cell division cycle 25B
chr13_+_97928395 0.038 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr19_-_10946871 0.038 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr22_+_30821732 0.038 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr1_-_205091115 0.037 ENST00000264515.6
ENST00000367164.1
RBBP5

retinoblastoma binding protein 5

chr1_-_173793458 0.037 ENST00000356198.2
CENPL
centromere protein L
chr16_-_67281413 0.037 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr19_+_589893 0.037 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr12_-_96793142 0.037 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17


cyclin-dependent kinase 17


chr15_+_64443905 0.037 ENST00000325881.4
SNX22
sorting nexin 22
chr1_-_246670614 0.036 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chrX_+_37545012 0.036 ENST00000378616.3
XK
X-linked Kx blood group (McLeod syndrome)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.2 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.2 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:2000974 trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0060032 notochord regression(GO:0060032)
0.0 0.0 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.0 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST_STAT3_PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling