Motif ID: NR1H4

Z-value: 0.436


Transcription factors associated with NR1H4:

Gene SymbolEntrez IDGene Name
NR1H4 ENSG00000012504.9 NR1H4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1H4hg19_v2_chr12_+_100897130_1008972310.561.2e-01Click!


Activity profile for motif NR1H4.

activity profile for motif NR1H4


Sorted Z-values histogram for motif NR1H4

Sorted Z-values for motif NR1H4



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_32042131 0.950 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_+_32042105 0.911 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_+_86046433 0.869 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr2_+_158114051 0.460 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr11_+_45868957 0.305 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr7_-_131241361 0.286 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr22_+_31090793 0.274 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2


oxysterol binding protein 2


chr14_-_69444957 0.258 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1


actinin, alpha 1


chr12_-_57914275 0.245 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3




DNA-damage-inducible transcript 3




chr6_+_43140095 0.204 ENST00000457278.2
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chrX_+_7137475 0.186 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr8_-_134511587 0.179 ENST00000523855.1
ENST00000523854.1
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr1_-_109584716 0.177 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47


WD repeat domain 47


chr1_+_25599018 0.175 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD




Rh blood group, D antigen




chr6_-_33547975 0.169 ENST00000442998.2
ENST00000360661.5
BAK1

BCL2-antagonist/killer 1

chr6_-_33548006 0.156 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr11_-_4414880 0.154 ENST00000254436.7
ENST00000543625.1
TRIM21

tripartite motif containing 21

chr16_+_81478775 0.145 ENST00000537098.3
CMIP
c-Maf inducing protein
chr1_-_109584768 0.144 ENST00000357672.3
WDR47
WD repeat domain 47
chr2_+_73441350 0.141 ENST00000389501.4
SMYD5
SMYD family member 5
chr1_-_153585539 0.135 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr1_-_109584608 0.133 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47



WD repeat domain 47



chr5_-_16916624 0.131 ENST00000513882.1
MYO10
myosin X
chr16_-_30537839 0.130 ENST00000380412.5
ZNF768
zinc finger protein 768
chr1_+_162351503 0.130 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr19_+_19496728 0.129 ENST00000537887.1
ENST00000417582.2
GATAD2A

GATA zinc finger domain containing 2A

chr19_+_11546440 0.127 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
PRKCSH





protein kinase C substrate 80K-H





chr17_+_7533439 0.126 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG







sex hormone-binding globulin







chr11_-_65625014 0.125 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr5_+_145316120 0.125 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr1_-_25747283 0.125 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE







Rh blood group, CcEe antigens







chr8_-_110346614 0.121 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr1_-_16939976 0.120 ENST00000430580.2
NBPF1
neuroblastoma breakpoint family, member 1
chr6_+_127588020 0.117 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146




ring finger protein 146




chr7_-_33140498 0.117 ENST00000448915.1
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr2_-_74374995 0.115 ENST00000295326.4
BOLA3
bolA family member 3
chr2_-_74780176 0.111 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr9_+_138391805 0.110 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr11_-_65624415 0.109 ENST00000524553.1
ENST00000527344.1
CFL1

cofilin 1 (non-muscle)

chr19_+_19496624 0.109 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A


GATA zinc finger domain containing 2A


chr12_-_7281469 0.107 ENST00000542370.1
ENST00000266560.3
RBP5

retinol binding protein 5, cellular

chr4_+_152330409 0.107 ENST00000513086.1
FAM160A1
family with sequence similarity 160, member A1
chr1_+_12123414 0.107 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr18_+_3449330 0.106 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr19_+_36239576 0.105 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr12_-_6451014 0.103 ENST00000366159.4
ENST00000539372.1
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr19_+_11546153 0.102 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr9_+_116343192 0.101 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr18_+_3448455 0.101 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr10_+_105726862 0.099 ENST00000335753.4
ENST00000369755.3
SLK

STE20-like kinase

chr12_-_6451186 0.097 ENST00000540022.1
ENST00000536194.1
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr16_+_69166770 0.096 ENST00000567235.2
ENST00000568448.1
CIRH1A

cirrhosis, autosomal recessive 1A (cirhin)

chr19_+_11546093 0.095 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr17_-_2117600 0.093 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr12_+_100967533 0.093 ENST00000550295.1
GAS2L3
growth arrest-specific 2 like 3
chr17_-_73257667 0.092 ENST00000538886.1
ENST00000580799.1
ENST00000351904.7
ENST00000537686.1
GGA3



golgi-associated, gamma adaptin ear containing, ARF binding protein 3



chr1_+_26560676 0.092 ENST00000451429.2
ENST00000252992.4
CEP85

centrosomal protein 85kDa

chr12_-_6451235 0.087 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr16_+_69166418 0.086 ENST00000314423.7
ENST00000562237.1
ENST00000567460.1
ENST00000566227.1
ENST00000352319.4
ENST00000563094.1
CIRH1A





cirrhosis, autosomal recessive 1A (cirhin)





chr6_+_127587755 0.086 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146





ring finger protein 146





chr10_-_35104185 0.086 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3










par-3 family cell polarity regulator










chr1_-_33642151 0.086 ENST00000543586.1
TRIM62
tripartite motif containing 62
chr11_-_65429891 0.084 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_+_26322409 0.084 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr5_+_145317356 0.083 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr17_-_74023291 0.083 ENST00000586740.1
EVPL
envoplakin
chr11_-_65430554 0.081 ENST00000308639.9
ENST00000406246.3
RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

chr12_+_52306113 0.081 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1


activin A receptor type II-like 1


chr7_-_752074 0.079 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_-_143395551 0.077 ENST00000507861.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr22_-_43567750 0.076 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr17_-_4852243 0.075 ENST00000225655.5
PFN1
profilin 1
chr2_+_113321939 0.074 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr1_-_25256368 0.074 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr2_+_179345173 0.073 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr11_-_118305921 0.072 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr22_+_45072925 0.072 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr9_+_74526384 0.071 ENST00000334731.2
ENST00000377031.3
C9orf85

chromosome 9 open reading frame 85

chr19_+_1026566 0.071 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2




calponin 2




chr11_+_67250490 0.070 ENST00000528641.2
ENST00000279146.3
AIP

aryl hydrocarbon receptor interacting protein

chr5_-_137878887 0.070 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1



eukaryotic translation termination factor 1



chr1_+_44412577 0.069 ENST00000372343.3
IPO13
importin 13
chr11_-_71639670 0.069 ENST00000533047.1
ENST00000529844.1
RP11-849H4.2

Putative short transient receptor potential channel 2-like protein

chr1_+_12123463 0.069 ENST00000417814.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr19_+_1026298 0.068 ENST00000263097.4
CNN2
calponin 2
chr17_-_74023474 0.068 ENST00000301607.3
EVPL
envoplakin
chr2_-_219433014 0.068 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37




ubiquitin specific peptidase 37




chr11_-_65430251 0.067 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA






v-rel avian reticuloendotheliosis viral oncogene homolog A






chr1_-_16539094 0.067 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr19_-_10613421 0.065 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr17_-_73840614 0.065 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr22_+_45072958 0.065 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr17_-_73839792 0.064 ENST00000590762.1
UNC13D
unc-13 homolog D (C. elegans)
chr1_+_1334914 0.063 ENST00000576232.1
ENST00000570344.1
RP4-758J18.2

HCG20425, isoform CRA_a; Uncharacterized protein; cDNA FLJ53815

chr12_-_68845165 0.063 ENST00000360485.3
ENST00000441255.2
RP11-81H14.2

RP11-81H14.2

chr11_-_57298187 0.062 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
TIMM10


translocase of inner mitochondrial membrane 10 homolog (yeast)


chr19_+_10563567 0.062 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_1083078 0.060 ENST00000574266.1
ENST00000302538.5
ABR

active BCR-related

chr1_+_36789335 0.058 ENST00000373137.2
RP11-268J15.5
RP11-268J15.5
chr12_+_100661156 0.058 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr19_+_677885 0.057 ENST00000591552.2
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr8_+_110346546 0.056 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2


enhancer of yellow 2 homolog (Drosophila)


chr12_+_67663056 0.056 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr7_+_99102573 0.056 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr6_-_131211534 0.056 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr11_-_7041466 0.055 ENST00000536068.1
ENST00000278314.4
ZNF214

zinc finger protein 214

chr15_+_101256294 0.055 ENST00000559755.1
RP11-66B24.5
RP11-66B24.5
chr1_-_6557156 0.054 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_+_4087664 0.054 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr1_+_21766641 0.054 ENST00000342104.5
NBPF3
neuroblastoma breakpoint family, member 3
chr2_-_106015527 0.054 ENST00000344213.4
ENST00000358129.4
FHL2

four and a half LIM domains 2

chr3_+_190105909 0.054 ENST00000456423.1
CLDN16
claudin 16
chrX_-_153141434 0.054 ENST00000407935.2
ENST00000439496.1
L1CAM

L1 cell adhesion molecule

chr19_-_10613862 0.052 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr8_-_131028660 0.052 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
FAM49B



family with sequence similarity 49, member B



chr12_-_16035195 0.052 ENST00000535752.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr20_+_62369623 0.051 ENST00000467211.1
RP4-583P15.14
RP4-583P15.14
chr11_-_58345569 0.051 ENST00000528954.1
ENST00000528489.1
LPXN

leupaxin

chr9_-_35685452 0.050 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr17_-_62308087 0.050 ENST00000583097.1
TEX2
testis expressed 2
chr11_-_71639446 0.050 ENST00000534704.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr11_-_64511575 0.049 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2


RAS guanyl releasing protein 2 (calcium and DAG-regulated)


chr21_-_46515493 0.048 ENST00000600921.1
PRED57
HCG401283; PRED57 protein; Uncharacterized protein
chr3_+_50316458 0.046 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr4_+_152330390 0.046 ENST00000503146.1
ENST00000435205.1
FAM160A1

family with sequence similarity 160, member A1

chr20_+_62496596 0.046 ENST00000369927.4
ENST00000346249.4
ENST00000348257.5
ENST00000352482.4
ENST00000351424.4
ENST00000217121.5
ENST00000358548.4
TPD52L2






tumor protein D52-like 2






chr9_-_138391692 0.045 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr2_-_47143160 0.045 ENST00000409800.1
ENST00000409218.1
MCFD2

multiple coagulation factor deficiency 2

chr10_-_119806085 0.044 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chrX_-_153141302 0.043 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM




L1 cell adhesion molecule




chr11_-_71639480 0.042 ENST00000529513.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr19_-_51220176 0.042 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1

chr5_+_138629628 0.042 ENST00000508689.1
ENST00000514528.1
MATR3

matrin 3

chr17_-_2615031 0.042 ENST00000576885.1
ENST00000574426.2
CLUH

clustered mitochondria (cluA/CLU1) homolog

chr5_+_149569520 0.042 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr22_+_20104947 0.042 ENST00000402752.1
RANBP1
RAN binding protein 1
chr20_-_45981138 0.041 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr9_-_35958151 0.041 ENST00000341959.2
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr3_-_120461378 0.040 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr17_-_4852332 0.040 ENST00000572383.1
PFN1
profilin 1
chr12_+_123874589 0.040 ENST00000437502.1
SETD8
SET domain containing (lysine methyltransferase) 8
chr3_+_160117418 0.040 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr8_+_9046503 0.040 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr19_-_10613361 0.039 ENST00000591039.1
ENST00000591419.1
KEAP1

kelch-like ECH-associated protein 1

chr16_+_58535372 0.039 ENST00000566656.1
ENST00000566618.1
NDRG4

NDRG family member 4

chr2_+_219433588 0.039 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr5_+_138629337 0.039 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
MATR3


matrin 3


chr11_-_116663127 0.039 ENST00000433069.1
ENST00000542499.1
APOA5

apolipoprotein A-V

chr14_-_21945057 0.037 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr8_-_131028869 0.037 ENST00000518283.1
ENST00000519110.1
FAM49B

family with sequence similarity 49, member B

chr2_+_219433281 0.037 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RQCD1


RCD1 required for cell differentiation1 homolog (S. pombe)


chr7_-_6066183 0.036 ENST00000422786.1
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr17_-_37764128 0.035 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chrX_-_48823165 0.035 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_+_36690011 0.034 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3


thyroid hormone receptor associated protein 3


chr11_-_71639613 0.034 ENST00000528184.1
ENST00000528511.2
RP11-849H4.2

Putative short transient receptor potential channel 2-like protein

chr5_+_140579162 0.033 ENST00000536699.1
ENST00000354757.3
PCDHB11

protocadherin beta 11

chr19_-_50311896 0.033 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr17_-_2614927 0.033 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr12_+_16035307 0.033 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
STRAP


serine/threonine kinase receptor associated protein


chr17_-_27181990 0.032 ENST00000583953.1
FAM222B
family with sequence similarity 222, member B
chr3_-_50383096 0.032 ENST00000442887.1
ENST00000360165.3
ZMYND10

zinc finger, MYND-type containing 10

chr19_-_42636617 0.031 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2




POU class 2 homeobox 2




chr1_+_33231221 0.031 ENST00000294521.3
KIAA1522
KIAA1522
chr3_-_120461353 0.031 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr22_+_21321531 0.030 ENST00000405089.1
ENST00000335375.5
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr1_+_33231268 0.030 ENST00000373480.1
KIAA1522
KIAA1522
chrX_-_152989798 0.029 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31



B-cell receptor-associated protein 31



chrX_+_106449862 0.028 ENST00000372453.3
ENST00000535523.1
PIH1D3

PIH1 domain containing 3

chr5_+_138629389 0.028 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
MATR3


matrin 3


chr22_+_20105012 0.026 ENST00000331821.3
ENST00000411892.1
RANBP1

RAN binding protein 1

chr12_+_120875910 0.025 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr3_+_14989186 0.025 ENST00000435454.1
ENST00000323373.6
NR2C2

nuclear receptor subfamily 2, group C, member 2

chr5_+_138629417 0.024 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3



matrin 3



chr21_-_16374688 0.024 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr19_-_56056888 0.024 ENST00000592464.1
ENST00000420723.3
SBK3

SH3 domain binding kinase family, member 3

chr7_+_2671663 0.024 ENST00000407643.1
TTYH3
tweety family member 3
chr1_+_156024552 0.024 ENST00000368304.5
ENST00000368302.3
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chrX_+_66764375 0.023 ENST00000374690.3
AR
androgen receptor
chr3_-_123512688 0.023 ENST00000475616.1
MYLK
myosin light chain kinase
chr10_+_90562705 0.023 ENST00000539337.1
LIPM
lipase, family member M
chr19_+_35629702 0.023 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr1_+_33207381 0.023 ENST00000401073.2
KIAA1522
KIAA1522
chr3_+_52828805 0.022 ENST00000416872.2
ENST00000449956.2
ITIH3

inter-alpha-trypsin inhibitor heavy chain 3

chr17_-_43568062 0.021 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr1_-_225616515 0.021 ENST00000338179.2
ENST00000425080.1
LBR

lamin B receptor

chr4_-_176733377 0.021 ENST00000505375.1
GPM6A
glycoprotein M6A
chr19_-_51893782 0.021 ENST00000570516.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr18_-_12377001 0.021 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr6_+_108616243 0.021 ENST00000421954.1
LACE1
lactation elevated 1
chr2_+_33172012 0.020 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr19_-_11689752 0.020 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chr17_-_9939854 0.020 ENST00000584146.2
GAS7
growth arrest-specific 7
chr17_+_72920370 0.019 ENST00000331427.4
OTOP2
otopetrin 2
chrX_-_153141783 0.019 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr16_+_30953696 0.019 ENST00000566320.2
ENST00000565939.1
FBXL19

F-box and leucine-rich repeat protein 19

chr17_-_73840415 0.019 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D


unc-13 homolog D (C. elegans)


chr2_+_33172221 0.019 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr1_-_27240455 0.019 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr19_+_50706866 0.018 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14




myosin, heavy chain 14, non-muscle





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.9 GO:0060591 apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.2 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.2 GO:0002432 granuloma formation(GO:0002432)
0.0 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.0 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0010736 serum response element binding(GO:0010736)
0.0 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases