Motif ID: NKX2-5

Z-value: 0.386


Transcription factors associated with NKX2-5:

Gene SymbolEntrez IDGene Name
NKX2-5 ENSG00000183072.9 NKX2-5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX2-5hg19_v2_chr5_-_172662303_1726623600.442.4e-01Click!


Activity profile for motif NKX2-5.

activity profile for motif NKX2-5


Sorted Z-values histogram for motif NKX2-5

Sorted Z-values for motif NKX2-5



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_13835147 0.508 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr22_-_38577782 0.372 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6





phospholipase A2, group VI (cytosolic, calcium-independent)





chr17_+_74261277 0.337 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr2_-_175499294 0.309 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr3_-_15374659 0.290 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr20_-_56285595 0.256 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr4_-_185729602 0.234 ENST00000437665.3
ACSL1
acyl-CoA synthetase long-chain family member 1
chr5_+_147258266 0.229 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr9_+_33265011 0.227 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr9_+_33264861 0.210 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr15_-_52944231 0.207 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr5_+_122110691 0.207 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr3_+_108321623 0.191 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr11_-_9482010 0.186 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr4_-_186682716 0.186 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr22_-_38577731 0.184 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr4_-_2264015 0.181 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr17_-_8279977 0.178 ENST00000396267.1
KRBA2
KRAB-A domain containing 2
chr10_+_111967345 0.177 ENST00000332674.5
ENST00000453116.1
MXI1

MAX interactor 1, dimerization protein

chr8_+_145729465 0.174 ENST00000394955.2
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
chr5_-_149516966 0.172 ENST00000517957.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_+_201936707 0.171 ENST00000433898.1
ENST00000454214.1
NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr16_-_30134524 0.168 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr16_-_30134441 0.163 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr6_-_112115074 0.162 ENST00000368667.2
FYN
FYN oncogene related to SRC, FGR, YES
chr7_+_151791095 0.162 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr16_-_30134266 0.156 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr17_-_46667594 0.149 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3


homeobox B3


chr9_+_35906176 0.144 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr16_+_68344877 0.143 ENST00000566657.1
ENST00000565745.1
ENST00000569571.1
ENST00000569047.3
ENST00000449359.3
PRMT7




protein arginine methyltransferase 7




chr5_-_74062930 0.138 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2



G elongation factor, mitochondrial 2



chr6_-_112115103 0.137 ENST00000462598.3
FYN
FYN oncogene related to SRC, FGR, YES
chr3_-_11685345 0.136 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr15_+_78799895 0.132 ENST00000408962.2
ENST00000388988.4
ENST00000360519.3
HYKK


hydroxylysine kinase


chr2_+_201936458 0.131 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr8_-_49834299 0.131 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_-_74062867 0.128 ENST00000509097.1
GFM2
G elongation factor, mitochondrial 2
chr12_-_51422017 0.124 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr7_-_94953878 0.122 ENST00000222381.3
PON1
paraoxonase 1
chr5_+_134181625 0.121 ENST00000394976.3
C5orf24
chromosome 5 open reading frame 24
chr1_-_22109484 0.121 ENST00000529637.1
USP48
ubiquitin specific peptidase 48
chr8_-_49833978 0.119 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr16_+_68344981 0.119 ENST00000441236.1
ENST00000348497.4
ENST00000339507.5
PRMT7


protein arginine methyltransferase 7


chr2_-_27545431 0.118 ENST00000233545.2
MPV17
MpV17 mitochondrial inner membrane protein
chr3_-_149095652 0.116 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr1_-_22109682 0.116 ENST00000400301.1
ENST00000532737.1
USP48

ubiquitin specific peptidase 48

chr20_-_44485835 0.116 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8


acyl-CoA thioesterase 8


chr1_+_186798073 0.115 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr3_-_113415441 0.113 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr9_+_118950325 0.113 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr4_+_153701081 0.109 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1




ADP-ribosylation factor interacting protein 1




chr8_-_73793975 0.103 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr15_+_78799948 0.103 ENST00000566332.1
HYKK
hydroxylysine kinase
chr17_+_27055798 0.101 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr19_+_14672755 0.100 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr12_+_56360550 0.093 ENST00000266970.4
CDK2
cyclin-dependent kinase 2
chr3_+_23847432 0.091 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chrX_+_115567767 0.091 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_-_26232951 0.088 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr19_+_5681011 0.088 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr12_-_123717711 0.088 ENST00000537854.1
MPHOSPH9
M-phase phosphoprotein 9
chr17_-_46667628 0.085 ENST00000498678.1
HOXB3
homeobox B3
chr1_+_202431859 0.083 ENST00000391959.3
ENST00000367270.4
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr2_-_85895295 0.083 ENST00000428225.1
ENST00000519937.2
SFTPB

surfactant protein B

chr7_-_99774945 0.080 ENST00000292377.2
GPC2
glypican 2
chr8_-_95220775 0.079 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr11_-_73689037 0.079 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr3_+_23847394 0.078 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr1_+_159796534 0.076 ENST00000289707.5
SLAMF8
SLAM family member 8
chr17_+_48624450 0.075 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20


spermatogenesis associated 20


chr3_-_47950745 0.073 ENST00000429422.1
MAP4
microtubule-associated protein 4
chrX_-_13835398 0.072 ENST00000475307.1
GPM6B
glycoprotein M6B
chr2_+_219646462 0.071 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chrY_+_16634483 0.069 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr3_+_124223586 0.064 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr1_+_203765437 0.064 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr3_+_46283863 0.063 ENST00000545097.1
ENST00000541018.1
CCR3

chemokine (C-C motif) receptor 3

chrX_-_154299501 0.063 ENST00000369484.3
ENST00000369476.3
CMC4
MTCP1
C-x(9)-C motif containing 4
mature T-cell proliferation 1
chr16_+_765092 0.060 ENST00000568223.2
METRN
meteorin, glial cell differentiation regulator
chr11_+_64879317 0.060 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2










transmembrane 7 superfamily member 2










chr5_-_102898465 0.060 ENST00000507423.1
ENST00000230792.2
NUDT12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr4_+_108746282 0.059 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr9_+_133986782 0.059 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr7_+_99775366 0.059 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr9_+_17579084 0.058 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr11_+_108093755 0.057 ENST00000527891.1
ENST00000532931.1
ATM

ataxia telangiectasia mutated

chr3_+_186692745 0.056 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_+_152214098 0.056 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr17_+_66521936 0.056 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_+_127020202 0.056 ENST00000373600.3
ENST00000320246.5
NEK6

NIMA-related kinase 6

chr8_+_76452097 0.054 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr14_+_78227105 0.053 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178



chromosome 14 open reading frame 178



chr7_+_99775520 0.051 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3


stromal antigen 3


chr12_-_70004942 0.050 ENST00000361484.3
LRRC10
leucine rich repeat containing 10
chr1_+_159796589 0.050 ENST00000368104.4
SLAMF8
SLAM family member 8
chr14_+_23654525 0.047 ENST00000399910.1
ENST00000492621.1
C14orf164

chromosome 14 open reading frame 164

chr2_-_220041617 0.046 ENST00000451647.1
ENST00000360507.5
CNPPD1

cyclin Pas1/PHO80 domain containing 1

chrX_+_150565038 0.046 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr4_-_153700864 0.046 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr11_-_108464321 0.046 ENST00000265843.4
EXPH5
exophilin 5
chr11_+_108093839 0.046 ENST00000452508.2
ATM
ataxia telangiectasia mutated
chr1_-_11907829 0.045 ENST00000376480.3
NPPA
natriuretic peptide A
chr16_+_77233294 0.044 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr3_-_194072019 0.043 ENST00000429275.1
ENST00000323830.3
CPN2

carboxypeptidase N, polypeptide 2

chr14_+_21467414 0.043 ENST00000554422.1
ENST00000298681.4
SLC39A2

solute carrier family 39 (zinc transporter), member 2

chr19_-_5680891 0.040 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr3_+_46283916 0.036 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr17_+_46048376 0.036 ENST00000338399.4
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr5_+_140729649 0.036 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr7_-_38969150 0.035 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr14_-_21516590 0.035 ENST00000555026.1
NDRG2
NDRG family member 2
chr19_+_16999654 0.035 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr17_-_55911970 0.034 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3

RP11-60A24.3

chr20_-_271304 0.034 ENST00000400269.3
ENST00000360321.2
C20orf96

chromosome 20 open reading frame 96

chr11_+_76813886 0.033 ENST00000529803.1
OMP
olfactory marker protein
chr12_+_111051902 0.033 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1



tectonic family member 1



chr2_-_25194963 0.032 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr12_+_111051832 0.032 ENST00000550703.2
ENST00000551590.1
TCTN1

tectonic family member 1

chr4_+_144354644 0.032 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chrX_-_14047996 0.030 ENST00000380523.4
ENST00000398355.3
GEMIN8

gem (nuclear organelle) associated protein 8

chrX_+_14547632 0.030 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chrX_-_115828156 0.030 ENST00000446495.1
RP11-232D9.3
RP11-232D9.3
chr7_+_130020180 0.029 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
CPA1


carboxypeptidase A1 (pancreatic)


chr10_+_73156664 0.029 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23



cadherin-related 23



chr17_-_79623597 0.029 ENST00000574024.1
ENST00000331056.5
PDE6G

phosphodiesterase 6G, cGMP-specific, rod, gamma

chr5_+_74062806 0.028 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr11_-_108464465 0.028 ENST00000525344.1
EXPH5
exophilin 5
chr5_-_76788317 0.027 ENST00000296679.4
WDR41
WD repeat domain 41
chr14_+_105927191 0.027 ENST00000550551.1
MTA1
metastasis associated 1
chr22_-_50523760 0.025 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523807 0.025 ENST00000442311.1
ENST00000538737.1
MLC1

megalencephalic leukoencephalopathy with subcortical cysts 1

chr14_+_81421355 0.025 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr3_-_187388173 0.025 ENST00000287641.3
SST
somatostatin
chr15_+_42696954 0.025 ENST00000337571.4
ENST00000569136.1
CAPN3

calpain 3, (p94)

chr18_+_42277095 0.024 ENST00000591940.1
SETBP1
SET binding protein 1
chr3_-_39234074 0.023 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1


xin actin-binding repeat containing 1


chrX_+_71353499 0.023 ENST00000373677.1
NHSL2
NHS-like 2
chr4_-_76861392 0.023 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr8_+_9009296 0.023 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr18_-_10672744 0.022 ENST00000582937.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr16_+_8814563 0.022 ENST00000425191.2
ENST00000569156.1
ABAT

4-aminobutyrate aminotransferase

chr1_-_214638146 0.022 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr19_-_5680499 0.021 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr8_+_48873453 0.021 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr10_-_81320151 0.020 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
SFTPA2


surfactant protein A2


chr18_+_42260861 0.020 ENST00000282030.5
SETBP1
SET binding protein 1
chr9_-_20382446 0.020 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr22_-_50523843 0.020 ENST00000535444.1
ENST00000431262.2
MLC1

megalencephalic leukoencephalopathy with subcortical cysts 1

chr9_+_116263639 0.020 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr15_+_42696992 0.019 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr18_+_13382553 0.019 ENST00000586222.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr20_+_57226284 0.019 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16






syntaxin 16






chr3_+_45984947 0.018 ENST00000304552.4
CXCR6
chemokine (C-X-C motif) receptor 6
chr8_-_72459885 0.016 ENST00000523987.1
RP11-1102P16.1
Uncharacterized protein
chr18_+_42260059 0.016 ENST00000426838.4
SETBP1
SET binding protein 1
chr7_-_37488777 0.016 ENST00000445322.1
ENST00000448602.1
ELMO1

engulfment and cell motility 1

chr7_+_142457315 0.015 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr14_-_68159152 0.015 ENST00000554035.1
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr6_-_134373732 0.015 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr7_+_6071007 0.015 ENST00000409061.1
ANKRD61
ankyrin repeat domain 61
chr18_+_19668021 0.014 ENST00000579830.1
RP11-595B24.2
Uncharacterized protein
chr17_-_19771216 0.014 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr2_-_162931052 0.014 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr13_+_24846799 0.014 ENST00000488060.1
SPATA13
spermatogenesis associated 13
chr13_+_95364963 0.014 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr5_+_55147205 0.014 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
IL31RA



interleukin 31 receptor A



chr17_-_56621665 0.013 ENST00000321691.3
C17orf47
chromosome 17 open reading frame 47
chr11_+_18417813 0.013 ENST00000540430.1
ENST00000379412.5
LDHA

lactate dehydrogenase A

chr8_+_48873479 0.013 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr1_+_211433275 0.013 ENST00000367005.4
RCOR3
REST corepressor 3
chr19_-_54584634 0.012 ENST00000432826.1
TARM1
T cell-interacting, activating receptor on myeloid cells 1
chr20_-_271009 0.011 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr7_-_37488834 0.011 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr2_-_180610767 0.011 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr1_-_55352834 0.010 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr22_-_50524298 0.010 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_+_133879193 0.010 ENST00000377869.1
ENST00000220616.4
TG

thyroglobulin

chr16_-_3149229 0.010 ENST00000572431.1
ENST00000572548.1
ZSCAN10

zinc finger and SCAN domain containing 10

chr12_-_50222187 0.009 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr10_+_76586348 0.009 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr17_+_4699439 0.009 ENST00000270586.3
PSMB6
proteasome (prosome, macropain) subunit, beta type, 6
chrX_-_55057403 0.009 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2



aminolevulinate, delta-, synthase 2



chr10_-_99531709 0.008 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr22_+_40322595 0.008 ENST00000420971.1
ENST00000544756.1
GRAP2

GRB2-related adaptor protein 2

chr17_+_38333263 0.008 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr18_+_61575200 0.008 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr14_+_81421710 0.007 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr1_-_36947120 0.007 ENST00000361632.4
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr22_+_40322623 0.007 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr7_-_14942467 0.006 ENST00000407950.1
ENST00000444700.2
DGKB

diacylglycerol kinase, beta 90kDa

chr3_+_46283944 0.006 ENST00000452454.1
ENST00000457243.1
CCR3

chemokine (C-C motif) receptor 3

chr15_+_81589254 0.006 ENST00000394652.2
IL16
interleukin 16
chr12_+_123717967 0.006 ENST00000536130.1
ENST00000546132.1
C12orf65

chromosome 12 open reading frame 65

chrX_+_86772707 0.005 ENST00000373119.4
KLHL4
kelch-like family member 4
chr14_+_64565442 0.004 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr7_-_81399438 0.004 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_+_110769258 0.003 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr1_+_161677034 0.003 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA




Fc receptor-like A




chr16_+_31483451 0.003 ENST00000565360.1
ENST00000361773.3
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr5_+_75699040 0.002 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.2 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.2 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0021546 rhombomere development(GO:0021546)
0.0 0.4 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)