Motif ID: NKX2-1

Z-value: 0.179


Transcription factors associated with NKX2-1:

Gene SymbolEntrez IDGene Name
NKX2-1 ENSG00000136352.13 NKX2-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX2-1hg19_v2_chr14_-_36990061_36990154-0.637.1e-02Click!


Activity profile for motif NKX2-1.

activity profile for motif NKX2-1


Sorted Z-values histogram for motif NKX2-1

Sorted Z-values for motif NKX2-1



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_89182156 0.118 ENST00000379224.5
 ISG20
interferon stimulated exonuclease gene 20kDa
chr8_+_70404996 0.108 ENST00000402687.4
ENST00000419716.3
 SULF1

sulfatase 1

chr22_+_50986462 0.106 ENST00000395676.2
 KLHDC7B
kelch domain containing 7B
chr2_-_157189180 0.088 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2




nuclear receptor subfamily 4, group A, member 2




chr15_+_89181974 0.066 ENST00000306072.5
 ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182178 0.065 ENST00000559876.1
 ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_228337553 0.054 ENST00000366714.2
 GJC2
gap junction protein, gamma 2, 47kDa
chr20_-_36793663 0.051 ENST00000536701.1
ENST00000536724.1
 TGM2

transglutaminase 2

chr3_+_187930491 0.050 ENST00000443217.1
 LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_43968306 0.048 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
 C6orf223


chromosome 6 open reading frame 223


chr4_+_144354644 0.045 ENST00000512843.1
 GAB1
GRB2-associated binding protein 1
chr7_-_24957699 0.045 ENST00000441059.1
ENST00000415162.1
 OSBPL3

oxysterol binding protein-like 3

chr19_-_17622269 0.045 ENST00000595116.1
 CTD-3131K8.2
CTD-3131K8.2
chrX_+_134478706 0.043 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
 ZNF449


zinc finger protein 449


chr7_+_99156212 0.042 ENST00000454654.1
 ZNF655
zinc finger protein 655
chr1_-_17338386 0.041 ENST00000341676.5
ENST00000452699.1
 ATP13A2

ATPase type 13A2

chrX_-_153236620 0.038 ENST00000369984.4
 HCFC1
host cell factor C1 (VP16-accessory protein)
chrX_-_153236819 0.037 ENST00000354233.3
 HCFC1
host cell factor C1 (VP16-accessory protein)
chrX_-_153237258 0.036 ENST00000310441.7
 HCFC1
host cell factor C1 (VP16-accessory protein)
chr18_+_42260861 0.036 ENST00000282030.5
 SETBP1
SET binding protein 1
chr17_+_38375528 0.036 ENST00000583268.1
 WIPF2
WAS/WASL interacting protein family, member 2
chr14_-_73360796 0.035 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
 DPF3


D4, zinc and double PHD fingers, family 3


chr7_+_150758642 0.035 ENST00000488420.1
 SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr1_+_202431859 0.035 ENST00000391959.3
ENST00000367270.4
 PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr17_-_8198636 0.035 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
 SLC25A35


solute carrier family 25, member 35


chr17_-_49198216 0.033 ENST00000262013.7
ENST00000357122.4
 SPAG9

sperm associated antigen 9

chr13_-_41240717 0.033 ENST00000379561.5
 FOXO1
forkhead box O1
chr15_+_76030311 0.032 ENST00000543887.1
 AC019294.1
AC019294.1
chr18_+_3450161 0.031 ENST00000551402.1
ENST00000577543.1
 TGIF1

TGFB-induced factor homeobox 1

chr16_+_640201 0.030 ENST00000563109.1
 RAB40C
RAB40C, member RAS oncogene family
chr11_-_62313090 0.030 ENST00000528508.1
ENST00000533365.1
 AHNAK

AHNAK nucleoprotein

chr15_-_44955842 0.030 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
 SPG11




spastic paraplegia 11 (autosomal recessive)




chr9_-_97356075 0.029 ENST00000375337.3
 FBP2
fructose-1,6-bisphosphatase 2
chrX_-_108976449 0.029 ENST00000469857.1
 ACSL4
acyl-CoA synthetase long-chain family member 4
chr3_-_49837254 0.029 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
 CDHR4


cadherin-related family member 4


chr11_-_65325203 0.029 ENST00000526927.1
ENST00000536982.1
 LTBP3

latent transforming growth factor beta binding protein 3

chr12_-_10978957 0.029 ENST00000240619.2
 TAS2R10
taste receptor, type 2, member 10
chr3_+_4535025 0.028 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
 ITPR1




inositol 1,4,5-trisphosphate receptor, type 1




chr17_+_61086917 0.028 ENST00000424789.2
ENST00000389520.4
 TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr6_-_42858534 0.028 ENST00000408925.2
 C6orf226
chromosome 6 open reading frame 226
chr14_+_67708344 0.028 ENST00000557237.1
 MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr19_+_50148087 0.027 ENST00000601038.1
ENST00000595242.1
 SCAF1

SR-related CTD-associated factor 1

chr3_+_187930429 0.027 ENST00000420410.1
 LPP
LIM domain containing preferred translocation partner in lipoma
chr17_+_46048471 0.026 ENST00000578018.1
ENST00000579175.1
 CDK5RAP3

CDK5 regulatory subunit associated protein 3

chr19_+_39903185 0.025 ENST00000409794.3
 PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr5_-_58335281 0.024 ENST00000358923.6
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_41487383 0.024 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
 SLFNL1



schlafen-like 1



chr8_+_94752349 0.024 ENST00000391680.1
 RBM12B-AS1
RBM12B antisense RNA 1
chr17_-_1508379 0.024 ENST00000412517.3
 SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr22_+_24891210 0.024 ENST00000382760.2
 UPB1
ureidopropionase, beta
chrX_-_108976410 0.023 ENST00000504980.1
 ACSL4
acyl-CoA synthetase long-chain family member 4
chr7_+_99156249 0.023 ENST00000449244.1
 ZNF655
zinc finger protein 655
chr11_-_65325430 0.023 ENST00000322147.4
 LTBP3
latent transforming growth factor beta binding protein 3
chr3_+_187930719 0.023 ENST00000312675.4
 LPP
LIM domain containing preferred translocation partner in lipoma
chr15_+_69452959 0.022 ENST00000261858.2
 GLCE
glucuronic acid epimerase
chr4_+_184826418 0.022 ENST00000308497.4
ENST00000438269.1
 STOX2

storkhead box 2

chr16_+_640055 0.022 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
 RAB40C


RAB40C, member RAS oncogene family


chr17_+_46048376 0.021 ENST00000338399.4
 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr18_-_24283586 0.021 ENST00000579458.1
 U3
Small nucleolar RNA U3
chr18_-_10791648 0.021 ENST00000583325.1
 PIEZO2
piezo-type mechanosensitive ion channel component 2
chr21_+_33671264 0.020 ENST00000339944.4
 MRAP
melanocortin 2 receptor accessory protein
chrX_-_70474377 0.020 ENST00000373978.1
ENST00000373981.1
 ZMYM3

zinc finger, MYM-type 3

chrX_-_32173579 0.019 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD




dystrophin




chr7_-_120497178 0.019 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
 TSPAN12


tetraspanin 12


chr9_+_33290491 0.019 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
 NFX1


nuclear transcription factor, X-box binding 1


chr1_+_180165672 0.018 ENST00000443059.1
 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr2_-_152118352 0.018 ENST00000331426.5
 RBM43
RNA binding motif protein 43
chr3_-_113464906 0.018 ENST00000477813.1
 NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr18_+_72166564 0.018 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
 CNDP2


CNDP dipeptidase 2 (metallopeptidase M20 family)


chr19_-_46234119 0.018 ENST00000317683.3
 FBXO46
F-box protein 46
chrX_-_70473957 0.017 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
 ZMYM3


zinc finger, MYM-type 3


chr3_+_4535155 0.017 ENST00000544951.1
 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr19_+_751122 0.017 ENST00000215582.6
 MISP
mitotic spindle positioning
chr2_+_128848740 0.017 ENST00000375990.3
 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr17_-_60005329 0.017 ENST00000251334.6
 INTS2
integrator complex subunit 2
chr5_+_131705438 0.017 ENST00000245407.3
 SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr17_+_66521936 0.017 ENST00000592800.1
 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_+_96077888 0.017 ENST00000509259.1
ENST00000503828.1
 CAST

calpastatin

chr17_-_42466864 0.017 ENST00000353281.4
ENST00000262407.5
 ITGA2B

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

chr16_+_2022036 0.015 ENST00000568546.1
 TBL3
transducin (beta)-like 3
chr19_+_36235964 0.015 ENST00000587708.2
 PSENEN
presenilin enhancer gamma secretase subunit
chr16_-_67190152 0.015 ENST00000486556.1
 TRADD
TNFRSF1A-associated via death domain
chr16_+_57126482 0.015 ENST00000537605.1
ENST00000535318.2
 CPNE2

copine II

chr8_-_144679602 0.015 ENST00000526710.1
 EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr8_-_94752946 0.014 ENST00000519109.1
 RBM12B
RNA binding motif protein 12B
chr1_+_206643806 0.014 ENST00000537984.1
 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr18_-_13915530 0.014 ENST00000327606.3
 MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr2_+_101591314 0.014 ENST00000450763.1
 NPAS2
neuronal PAS domain protein 2
chr16_+_57126428 0.013 ENST00000290776.8
 CPNE2
copine II
chrX_-_70474499 0.013 ENST00000353904.2
 ZMYM3
zinc finger, MYM-type 3
chr18_+_56806701 0.013 ENST00000587834.1
 SEC11C
SEC11 homolog C (S. cerevisiae)
chr8_+_145203548 0.013 ENST00000534366.1
 MROH1
maestro heat-like repeat family member 1
chr12_+_7941989 0.012 ENST00000229307.4
 NANOG
Nanog homeobox
chr9_-_14313641 0.012 ENST00000380953.1
 NFIB
nuclear factor I/B
chr16_-_18937072 0.012 ENST00000569122.1
 SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_-_15735925 0.012 ENST00000427824.1
 RP3-467K16.4
RP3-467K16.4
chr15_+_57511609 0.011 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
 TCF12


transcription factor 12


chr1_+_206643787 0.011 ENST00000367120.3
 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr16_-_58663720 0.011 ENST00000564557.1
ENST00000569240.1
ENST00000441024.2
ENST00000569020.1
ENST00000317147.5
 CNOT1




CCR4-NOT transcription complex, subunit 1




chr14_-_103989033 0.011 ENST00000553878.1
ENST00000557530.1
 CKB

creatine kinase, brain

chr17_+_40610862 0.011 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
 ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr8_+_132916318 0.011 ENST00000254624.5
ENST00000522709.1
 EFR3A

EFR3 homolog A (S. cerevisiae)

chr3_+_39149145 0.011 ENST00000301819.6
ENST00000431162.2
 TTC21A

tetratricopeptide repeat domain 21A

chr1_+_204485571 0.010 ENST00000454264.2
ENST00000367183.3
 MDM4

Mdm4 p53 binding protein homolog (mouse)

chr2_+_220299547 0.010 ENST00000312358.7
 SPEG
SPEG complex locus
chr8_+_145065705 0.010 ENST00000533044.1
 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_-_104827425 0.009 ENST00000393150.3
 CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_-_160232197 0.009 ENST00000419626.1
ENST00000610139.1
ENST00000475733.1
ENST00000407642.2
ENST00000368073.3
ENST00000326837.2
 DCAF8





DDB1 and CUL4 associated factor 8





chr6_-_137113604 0.009 ENST00000359015.4
 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chrX_-_134478012 0.009 ENST00000370766.3
 ZNF75D
zinc finger protein 75D
chr10_+_63808970 0.009 ENST00000309334.5
 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_-_60005365 0.009 ENST00000444766.3
 INTS2
integrator complex subunit 2
chr8_-_28747424 0.009 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
 INTS9




integrator complex subunit 9




chr2_-_133429091 0.009 ENST00000345008.6
 LYPD1
LY6/PLAUR domain containing 1
chr6_+_32121218 0.009 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
 PPT2


palmitoyl-protein thioesterase 2


chr11_+_66512089 0.009 ENST00000524551.1
ENST00000525908.1
ENST00000360962.4
ENST00000346672.4
ENST00000527634.1
ENST00000540737.1
 C11orf80





chromosome 11 open reading frame 80





chr10_-_103454876 0.009 ENST00000331272.7
 FBXW4
F-box and WD repeat domain containing 4
chr17_+_46048497 0.009 ENST00000583352.1
 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr7_+_150782945 0.009 ENST00000463381.1
 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr17_-_3499125 0.008 ENST00000399759.3
 TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr15_+_74911430 0.008 ENST00000562670.1
ENST00000564096.1
 CLK3

CDC-like kinase 3

chr19_-_39390212 0.008 ENST00000437828.1
 SIRT2
sirtuin 2
chr1_-_25291475 0.008 ENST00000338888.3
ENST00000399916.1
 RUNX3

runt-related transcription factor 3

chr2_-_176033066 0.007 ENST00000437522.1
 ATF2
activating transcription factor 2
chr2_+_85646054 0.007 ENST00000389938.2
 SH2D6
SH2 domain containing 6
chr11_+_46193466 0.007 ENST00000533793.1
 RP11-702F3.3
RP11-702F3.3
chr1_+_207277590 0.007 ENST00000367070.3
 C4BPA
complement component 4 binding protein, alpha
chr19_+_55014085 0.007 ENST00000351841.2
 LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr3_-_52029830 0.006 ENST00000492277.1
ENST00000475248.1
ENST00000479017.1
ENST00000495383.1
ENST00000466397.1
ENST00000481629.1
 RPL29





ribosomal protein L29





chr19_-_39390350 0.006 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2


sirtuin 2


chr15_-_43029252 0.006 ENST00000563260.1
ENST00000356231.3
 CDAN1

codanin 1

chr6_-_149806105 0.006 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
 ZC3H12D



zinc finger CCCH-type containing 12D



chr2_+_152266604 0.006 ENST00000430328.2
 RIF1
RAP1 interacting factor homolog (yeast)
chr11_-_105948129 0.006 ENST00000526793.1
 KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr3_-_16524357 0.006 ENST00000432519.1
 RFTN1
raftlin, lipid raft linker 1
chr8_+_145065521 0.006 ENST00000534791.1
 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr21_+_45432174 0.006 ENST00000380221.3
ENST00000291574.4
 TRAPPC10

trafficking protein particle complex 10

chr6_-_75828774 0.005 ENST00000493109.2
 COL12A1
collagen, type XII, alpha 1
chr1_-_182369751 0.005 ENST00000367565.1
 TEDDM1
transmembrane epididymal protein 1
chr6_+_32121789 0.005 ENST00000437001.2
ENST00000375137.2
 PPT2

palmitoyl-protein thioesterase 2

chr11_+_66512303 0.005 ENST00000532565.2
 C11orf80
chromosome 11 open reading frame 80
chr6_-_160679905 0.005 ENST00000366953.3
 SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr3_-_52029958 0.005 ENST00000294189.6
 RPL29
ribosomal protein L29
chr11_-_73472096 0.005 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
 RAB6A



RAB6A, member RAS oncogene family



chr12_-_719573 0.004 ENST00000397265.3
 NINJ2
ninjurin 2
chr15_-_44116873 0.004 ENST00000267812.3
 MFAP1
microfibrillar-associated protein 1
chr17_-_34195889 0.004 ENST00000311880.2
 C17orf66
chromosome 17 open reading frame 66
chr17_-_34195862 0.004 ENST00000592980.1
ENST00000587626.1
 C17orf66

chromosome 17 open reading frame 66

chrX_-_119693745 0.004 ENST00000371323.2
 CUL4B
cullin 4B
chr1_-_228604328 0.003 ENST00000355586.4
ENST00000366698.2
ENST00000520264.1
ENST00000479800.1
ENST00000295033.3
 TRIM17




tripartite motif containing 17




chr1_-_68698222 0.003 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS



wntless Wnt ligand secretion mediator



chr11_-_86383650 0.003 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
 ME3



malic enzyme 3, NADP(+)-dependent, mitochondrial



chr19_+_48972265 0.003 ENST00000452733.2
 CYTH2
cytohesin 2
chr8_-_144679296 0.003 ENST00000317198.6
 EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr3_-_56950407 0.003 ENST00000496106.1
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_5830768 0.002 ENST00000381506.3
 ERMP1
endoplasmic reticulum metallopeptidase 1
chr5_-_171615315 0.002 ENST00000176763.5
 STK10
serine/threonine kinase 10
chr3_-_139195350 0.002 ENST00000232217.2
 RBP2
retinol binding protein 2, cellular
chr19_+_1942453 0.002 ENST00000591752.1
 CSNK1G2
casein kinase 1, gamma 2
chr4_-_54930790 0.002 ENST00000263921.3
 CHIC2
cysteine-rich hydrophobic domain 2
chr8_-_67341208 0.002 ENST00000499642.1
 RP11-346I3.4
RP11-346I3.4
chr20_-_45142154 0.002 ENST00000347606.4
ENST00000457685.2
 ZNF334

zinc finger protein 334

chr9_+_133986782 0.001 ENST00000372301.2
 AIF1L
allograft inflammatory factor 1-like
chr19_+_48958766 0.001 ENST00000342291.2
 KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr12_+_121416489 0.001 ENST00000541395.1
ENST00000544413.1
 HNF1A

HNF1 homeobox A

chr10_+_111967345 0.001 ENST00000332674.5
ENST00000453116.1
 MXI1

MAX interactor 1, dimerization protein

chr3_+_121311966 0.001 ENST00000338040.4
 FBXO40
F-box protein 40
chr7_+_99156145 0.000 ENST00000452314.1
ENST00000252713.4
 ZNF655

zinc finger protein 655

chr7_+_127881325 0.000 ENST00000308868.4
 LEP
leptin
chr1_+_178694300 0.000 ENST00000367635.3
 RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_230787879 0.000 ENST00000435716.1
 TRIP12
thyroid hormone receptor interactor 12
chr11_-_105948040 0.000 ENST00000534815.1
 KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr2_-_225266802 0.000 ENST00000243806.2
 FAM124B
family with sequence similarity 124B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.0 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)