Motif ID: NFIA

Z-value: 0.568


Transcription factors associated with NFIA:

Gene SymbolEntrez IDGene Name
NFIA ENSG00000162599.11 NFIA

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61548374_615484260.412.8e-01Click!


Activity profile for motif NFIA.

activity profile for motif NFIA


Sorted Z-values histogram for motif NFIA

Sorted Z-values for motif NFIA



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_69180083 0.512 ENST00000328895.4
GKN2
gastrokine 2
chr2_-_69180012 0.425 ENST00000481498.1
GKN2
gastrokine 2
chr3_+_101498074 0.329 ENST00000273347.5
ENST00000474165.1
NXPE3

neurexophilin and PC-esterase domain family, member 3

chr19_+_41725088 0.295 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr9_+_130911723 0.289 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr2_+_102953608 0.285 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr19_+_41725140 0.282 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr15_+_67458357 0.261 ENST00000537194.2
SMAD3
SMAD family member 3
chr2_-_111291587 0.254 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr11_-_122931881 0.244 ENST00000526110.1
ENST00000227378.3
HSPA8

heat shock 70kDa protein 8

chr9_+_130911770 0.240 ENST00000372998.1
LCN2
lipocalin 2
chr1_+_68150744 0.236 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr6_+_106959718 0.230 ENST00000369066.3
AIM1
absent in melanoma 1
chr3_+_101498026 0.222 ENST00000495842.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr17_-_39661849 0.220 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13



keratin 13



chr7_+_129932974 0.179 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr2_+_33701707 0.176 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3


RAS guanyl releasing protein 3 (calcium and DAG-regulated)


chr4_+_14113592 0.164 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085



long intergenic non-protein coding RNA 1085



chr5_-_66492562 0.155 ENST00000256447.4
CD180
CD180 molecule
chr13_-_34250861 0.154 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3

RP11-141M1.3

chr12_-_70093111 0.152 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3



bestrophin 3



chr2_+_21444025 0.148 ENST00000435237.1
ENST00000457901.1
AC067959.1

AC067959.1

chr17_-_39538550 0.147 ENST00000394001.1
KRT34
keratin 34
chr11_-_104480019 0.145 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1


RP11-886D15.1


chr7_-_27135591 0.144 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr12_-_15038779 0.144 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr3_+_152017924 0.143 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
MBNL1



muscleblind-like splicing regulator 1



chr1_+_66797687 0.141 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr5_-_137374288 0.130 ENST00000514310.1
FAM13B
family with sequence similarity 13, member B
chr4_+_79567057 0.129 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2

long intergenic non-protein coding RNA 1094

chr21_-_35340759 0.128 ENST00000607953.1
AP000569.9
AP000569.9
chr16_+_22518495 0.125 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr21_+_35552978 0.123 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310


long intergenic non-protein coding RNA 310


chr14_+_77582905 0.121 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr11_-_128392085 0.121 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr9_-_129884902 0.118 ENST00000373417.1
ANGPTL2
angiopoietin-like 2
chr17_+_79027155 0.117 ENST00000572918.1
BAIAP2
BAI1-associated protein 2
chr5_-_74807418 0.116 ENST00000405807.4
ENST00000261415.7
COL4A3BP

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr17_+_79031415 0.116 ENST00000572073.1
ENST00000573677.1
BAIAP2

BAI1-associated protein 2

chrX_+_37639302 0.115 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr4_-_114900831 0.112 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr3_+_152017360 0.112 ENST00000485910.1
ENST00000463374.1
MBNL1

muscleblind-like splicing regulator 1

chr3_+_69812877 0.111 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr7_+_17338239 0.110 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr15_+_67418047 0.110 ENST00000540846.2
SMAD3
SMAD family member 3
chr3_+_69812701 0.109 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr3_+_101498269 0.109 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_-_192635943 0.108 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr4_-_48271802 0.105 ENST00000381501.3
TEC
tec protein tyrosine kinase
chr3_+_69928256 0.105 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chrX_+_37639264 0.104 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr3_-_194188956 0.103 ENST00000256031.4
ENST00000446356.1
ATP13A3

ATPase type 13A3

chrX_-_119693745 0.102 ENST00000371323.2
CUL4B
cullin 4B
chr3_+_69788576 0.099 ENST00000352241.4
ENST00000448226.2
MITF

microphthalmia-associated transcription factor

chr10_-_61469837 0.098 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr9_-_127710292 0.096 ENST00000421514.1
GOLGA1
golgin A1
chr5_+_74807581 0.096 ENST00000241436.4
ENST00000352007.5
POLK

polymerase (DNA directed) kappa

chr8_+_67344710 0.096 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1


alcohol dehydrogenase, iron containing, 1


chr1_+_168250194 0.093 ENST00000367821.3
TBX19
T-box 19
chr2_-_96812751 0.093 ENST00000449242.1
AC012307.2
AC012307.2
chr7_-_17598506 0.093 ENST00000451792.1
AC017060.1
AC017060.1
chr5_-_142784101 0.092 ENST00000503201.1
ENST00000502892.1
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr16_-_66785497 0.090 ENST00000440564.2
ENST00000379482.2
ENST00000443351.2
ENST00000566150.1
DYNC1LI2



dynein, cytoplasmic 1, light intermediate chain 2



chr13_+_49684445 0.089 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr2_+_54684327 0.089 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr5_+_173316341 0.088 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr13_-_100624012 0.087 ENST00000267294.4
ZIC5
Zic family member 5
chr6_-_86353510 0.087 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_15986364 0.087 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr1_+_41447609 0.086 ENST00000543104.1
CTPS1
CTP synthase 1
chr12_-_13248598 0.086 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr12_-_70093065 0.085 ENST00000553096.1
BEST3
bestrophin 3
chr3_+_149191723 0.085 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr2_+_136289030 0.085 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3HDM1



R3H domain containing 1



chr5_+_122847908 0.084 ENST00000511130.2
ENST00000512718.3
CSNK1G3

casein kinase 1, gamma 3

chr12_+_49621658 0.083 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr2_+_173955327 0.083 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr5_-_43313269 0.083 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr3_-_37216055 0.083 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr11_-_122930121 0.082 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr2_+_33701286 0.082 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_112073544 0.082 ENST00000257430.4
ENST00000508376.2
APC

adenomatous polyposis coli

chr15_+_36994210 0.081 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr5_+_112074029 0.081 ENST00000512211.2
APC
adenomatous polyposis coli
chr15_+_38544476 0.081 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr5_+_50678921 0.080 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr1_-_243417762 0.079 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr8_-_125827922 0.078 ENST00000533516.1
RP11-1082L8.4
RP11-1082L8.4
chr12_-_7281469 0.078 ENST00000542370.1
ENST00000266560.3
RBP5

retinol binding protein 5, cellular

chr11_-_111749767 0.076 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr9_+_17135016 0.076 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN


centlein, centrosomal protein


chr4_+_76439095 0.075 ENST00000506261.1
THAP6
THAP domain containing 6
chr16_+_22524379 0.075 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr2_-_33824336 0.075 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A


family with sequence similarity 98, member A


chr11_+_7506837 0.075 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr12_+_110718428 0.074 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_+_110001723 0.073 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_46379254 0.073 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr6_+_108977520 0.073 ENST00000540898.1
FOXO3
forkhead box O3
chr1_+_201159914 0.072 ENST00000335211.4
ENST00000451870.2
ENST00000295591.8
IGFN1


immunoglobulin-like and fibronectin type III domain containing 1


chr6_-_56492816 0.071 ENST00000522360.1
DST
dystonin
chr19_+_42254885 0.071 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr4_+_169633310 0.070 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr6_-_32784687 0.070 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr17_+_7323634 0.069 ENST00000323675.3
SPEM1
spermatid maturation 1
chr3_+_159570722 0.069 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr16_-_4164027 0.069 ENST00000572288.1
ADCY9
adenylate cyclase 9
chr5_+_50679506 0.069 ENST00000511384.1
ISL1
ISL LIM homeobox 1
chr1_+_44399466 0.069 ENST00000498139.2
ENST00000491846.1
ARTN

artemin

chr12_+_82752275 0.069 ENST00000248306.3
METTL25
methyltransferase like 25
chr7_+_66800928 0.068 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr1_+_44399347 0.068 ENST00000477048.1
ENST00000471394.2
ARTN

artemin

chr14_+_58797974 0.067 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr5_-_142783694 0.067 ENST00000394466.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chrX_-_85302531 0.066 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
CHM


choroideremia (Rab escort protein 1)


chr8_+_86999516 0.066 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_-_25824872 0.066 ENST00000308710.5
NGLY1
N-glycanase 1
chr7_-_151330218 0.065 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr11_-_10822029 0.065 ENST00000528839.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr3_+_152017181 0.064 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr12_-_99038732 0.064 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP



IKBKB interacting protein



chr9_-_129885010 0.064 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr2_-_219925189 0.064 ENST00000295731.6
IHH
indian hedgehog
chr2_+_192141611 0.063 ENST00000392316.1
MYO1B
myosin IB
chrX_-_10544942 0.063 ENST00000380779.1
MID1
midline 1 (Opitz/BBB syndrome)
chrX_-_84363974 0.063 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1


spermidine/spermine N1-acetyl transferase-like 1


chr14_-_54418598 0.063 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr12_-_53207842 0.063 ENST00000458244.2
KRT4
keratin 4
chr5_-_142784888 0.061 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_+_169552748 0.061 ENST00000504519.1
ENST00000512127.1
PALLD

palladin, cytoskeletal associated protein

chr1_-_243326612 0.061 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170


centrosomal protein 170kDa


chr6_-_56716686 0.060 ENST00000520645.1
DST
dystonin
chr12_-_52946923 0.060 ENST00000267119.5
KRT71
keratin 71
chr7_+_79764104 0.060 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_-_42418999 0.060 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr14_-_98444386 0.059 ENST00000556462.1
ENST00000556138.1
C14orf64

chromosome 14 open reading frame 64

chr1_+_95975672 0.059 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1

RP11-286B14.1

chr12_-_49449107 0.058 ENST00000301067.7
KMT2D
lysine (K)-specific methyltransferase 2D
chr17_-_67057047 0.058 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9


ATP-binding cassette, sub-family A (ABC1), member 9


chr12_+_10331605 0.058 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr7_-_105319536 0.058 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr19_-_33462816 0.057 ENST00000305768.5
ENST00000590597.2
CEP89

centrosomal protein 89kDa

chr11_-_13461790 0.057 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr16_+_8891670 0.056 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2



phosphomannomutase 2



chr9_+_17134980 0.056 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr16_-_15474904 0.055 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr7_-_56160625 0.055 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1



phosphorylase kinase, gamma 1 (muscle)



chr5_+_96271141 0.055 ENST00000231368.5
LNPEP
leucyl/cystinyl aminopeptidase
chr15_-_79576156 0.055 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4





RP11-17L5.4





chrX_-_48768913 0.055 ENST00000376529.3
ENST00000247138.5
ENST00000413561.2
ENST00000452555.2
ENST00000445167.2
ENST00000376512.1
SLC35A2





solute carrier family 35 (UDP-galactose transporter), member A2





chr14_-_50319758 0.055 ENST00000298310.5
NEMF
nuclear export mediator factor
chr1_-_1009683 0.055 ENST00000453464.2
RNF223
ring finger protein 223
chr3_-_25824925 0.054 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1


N-glycanase 1


chr12_-_49453557 0.054 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr4_-_21699380 0.054 ENST00000382148.3
KCNIP4
Kv channel interacting protein 4
chr14_+_55494323 0.054 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr12_-_82752565 0.053 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr4_+_95373037 0.053 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5










PDZ and LIM domain 5










chr16_+_56226405 0.053 ENST00000565363.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr6_-_160209471 0.053 ENST00000539948.1
TCP1
t-complex 1
chr19_-_13947099 0.052 ENST00000587762.1
MIR24-2
microRNA 24-2
chr16_+_22524844 0.052 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5



nuclear pore complex interacting protein family, member B5



chr5_+_89770696 0.052 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr2_+_159651821 0.052 ENST00000309950.3
ENST00000409042.1
DAPL1

death associated protein-like 1

chr9_+_103204553 0.052 ENST00000334943.6
ENST00000502978.1
TMEFF1
MSANTD3-TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
MSANTD3-TMEFF1 readthrough
chr10_+_22614547 0.052 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chrX_+_122993657 0.052 ENST00000434753.3
ENST00000430625.1
XIAP

X-linked inhibitor of apoptosis

chr9_+_35806082 0.051 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr10_-_128110441 0.051 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr5_-_43313574 0.051 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr17_-_40540484 0.051 ENST00000588969.1
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr7_-_99381798 0.051 ENST00000415003.1
ENST00000354593.2
CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

chr3_-_176914191 0.051 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1


transducin (beta)-like 1 X-linked receptor 1


chrX_+_122994112 0.050 ENST00000355640.3
XIAP
X-linked inhibitor of apoptosis
chr2_-_145277569 0.050 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr3_+_184033551 0.050 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr5_-_148929848 0.050 ENST00000504676.1
ENST00000515435.1
CSNK1A1

casein kinase 1, alpha 1

chr3_+_184032919 0.049 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr11_+_33037652 0.049 ENST00000311388.3
DEPDC7
DEP domain containing 7
chr14_-_61124977 0.049 ENST00000554986.1
SIX1
SIX homeobox 1
chr11_-_118023490 0.049 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr6_+_42989344 0.049 ENST00000244496.5
RRP36
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr19_+_15160130 0.048 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr11_-_118134997 0.048 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr1_+_170501270 0.048 ENST00000367763.3
ENST00000367762.1
GORAB

golgin, RAB6-interacting

chr2_-_180871780 0.048 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22


CWC22 spliceosome-associated protein homolog (S. cerevisiae)


chr17_-_40540377 0.047 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
STAT3



signal transducer and activator of transcription 3 (acute-phase response factor)



chr14_-_75079026 0.047 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr7_-_68895857 0.047 ENST00000421513.1
RP11-3P22.2
RP11-3P22.2
chr5_+_121647386 0.047 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP



synuclein, alpha interacting protein



chr19_+_49258775 0.047 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr11_-_123185475 0.047 ENST00000527774.1
ENST00000527533.1
RP11-109E10.1

RP11-109E10.1

chr11_-_65626753 0.047 ENST00000526975.1
ENST00000531413.1
CFL1

cofilin 1 (non-muscle)

chr16_-_67185117 0.047 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr6_-_10115007 0.046 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr9_+_133569108 0.046 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2





exosome component 2





chr18_-_12884259 0.046 ENST00000353319.4
ENST00000327283.3
PTPN2

protein tyrosine phosphatase, non-receptor type 2

chr19_+_33463127 0.046 ENST00000589646.1
ENST00000588258.1
ENST00000590179.1
C19orf40


chromosome 19 open reading frame 40


chr18_+_77155856 0.046 ENST00000253506.5
ENST00000591814.1
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr1_-_91317072 0.045 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1

RP4-665J23.1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.6 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.0 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0021603 cranial nerve formation(GO:0021603) semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.0 GO:0071415 response to caffeine(GO:0031000) cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.0 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.6 GO:0033643 host cell part(GO:0033643)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL