Motif ID: NFATC2_NFATC3

Z-value: 0.590

Transcription factors associated with NFATC2_NFATC3:

Gene SymbolEntrez IDGene Name
NFATC2 ENSG00000101096.15 NFATC2
NFATC3 ENSG00000072736.14 NFATC3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v2_chr20_-_50179368_50179392-0.933.5e-04Click!
NFATC3hg19_v2_chr16_+_68119247_68119293-0.393.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_92413353 1.242 ENST00000556154.1
FBLN5
fibulin 5
chr14_-_92413727 1.209 ENST00000267620.10
FBLN5
fibulin 5
chr2_+_20650796 0.809 ENST00000448241.1
AC023137.2
AC023137.2
chr1_-_151798546 0.731 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr4_-_186733363 0.689 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr4_-_186877502 0.625 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr11_+_65190245 0.621 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1


nuclear paraspeckle assembly transcript 1 (non-protein coding)


chr17_+_4853442 0.567 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr3_+_99357319 0.492 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1


collagen, type VIII, alpha 1


chr3_+_140981456 0.489 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr15_+_43985084 0.459 ENST00000434505.1
ENST00000411750.1
CKMT1A

creatine kinase, mitochondrial 1A

chr6_-_64029879 0.443 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr2_-_163099546 0.438 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr6_-_112081113 0.429 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr15_+_43885252 0.426 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B



creatine kinase, mitochondrial 1B



chr11_-_9482010 0.409 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr2_-_163099885 0.395 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr1_+_45274154 0.378 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr3_-_114035026 0.367 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr15_+_49715293 0.364 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr2_-_163100045 0.362 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr8_+_70404996 0.358 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr5_-_111093759 0.352 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP



neuronal regeneration related protein



chrX_+_133941218 0.338 ENST00000370784.4
ENST00000370785.3
FAM122C

family with sequence similarity 122C

chr20_+_12989596 0.328 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr4_-_186877481 0.313 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr12_+_51318513 0.313 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr4_-_186732892 0.309 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr5_-_34043310 0.308 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr6_-_136788001 0.299 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr4_-_186877806 0.297 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr11_-_46142948 0.297 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr11_-_119187826 0.293 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr12_+_54447637 0.289 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr15_+_49715449 0.288 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr12_-_91573249 0.285 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN


decorin


chr2_-_190044480 0.283 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_+_93443419 0.280 ENST00000557381.1
ENST00000420239.2
CHD2

chromodomain helicase DNA binding protein 2

chr3_-_98241760 0.280 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1










claudin domain containing 1










chr17_-_17740325 0.260 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr4_-_186578674 0.259 ENST00000438278.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_2334888 0.251 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr10_+_111967345 0.250 ENST00000332674.5
ENST00000453116.1
MXI1

MAX interactor 1, dimerization protein

chr12_-_91573316 0.248 ENST00000393155.1
DCN
decorin
chr15_-_40401062 0.243 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr18_-_10701979 0.242 ENST00000538948.1
ENST00000285141.4
PIEZO2

piezo-type mechanosensitive ion channel component 2

chr17_+_79953310 0.241 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr2_-_183387430 0.238 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_-_186733119 0.234 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr5_-_38845812 0.233 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1

CTD-2127H9.1

chr3_+_111578027 0.230 ENST00000431670.2
ENST00000412622.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr2_-_183387064 0.230 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr5_+_135394840 0.230 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr3_+_108321623 0.228 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr5_-_64777733 0.226 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr3_+_111578131 0.221 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr17_+_27046988 0.214 ENST00000496182.1
RPL23A
ribosomal protein L23a
chr1_-_149908710 0.214 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11


myotubularin related protein 11


chr2_-_183387283 0.211 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_-_98241598 0.208 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1



claudin domain containing 1



chrX_-_63005405 0.208 ENST00000374878.1
ENST00000437457.2
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr11_-_69867159 0.203 ENST00000528507.1
RP11-626H12.2
RP11-626H12.2
chr1_+_186265399 0.201 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr1_+_174846570 0.200 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr8_-_57123815 0.198 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr21_+_35107346 0.197 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr10_-_62704005 0.196 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr5_-_111091948 0.195 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_-_141747950 0.194 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_13299186 0.190 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr5_+_32788945 0.188 ENST00000326958.1
AC026703.1
AC026703.1
chr1_+_153651078 0.187 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr10_+_99079008 0.184 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr3_+_160473996 0.182 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr18_+_11851383 0.181 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr3_+_9944492 0.180 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE


interleukin 17 receptor E


chr17_-_1389228 0.179 ENST00000438665.2
MYO1C
myosin IC
chr8_+_81397876 0.177 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr17_-_49337392 0.176 ENST00000376381.2
ENST00000586178.1
MBTD1

mbt domain containing 1

chr12_+_12764773 0.174 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr9_-_97356075 0.174 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr12_-_122240792 0.173 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr17_+_27047244 0.173 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
RPL23A


ribosomal protein L23a


chr18_-_48346415 0.173 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr1_-_151319283 0.172 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_-_151319318 0.171 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5


regulatory factor X, 5 (influences HLA class II expression)


chr8_-_81787006 0.170 ENST00000327835.3
ZNF704
zinc finger protein 704
chr20_+_12989822 0.168 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr7_+_120629653 0.167 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1

chr11_-_82782861 0.165 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr14_+_21156915 0.163 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr11_+_19799327 0.163 ENST00000540292.1
NAV2
neuron navigator 2
chr4_-_71532207 0.161 ENST00000543780.1
ENST00000391614.3
IGJ

immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

chr6_+_136172820 0.158 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr8_+_52730143 0.157 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr11_-_57283159 0.155 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr9_+_19049372 0.154 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr12_-_104443890 0.154 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2


glycosyltransferase 8 domain containing 2


chr17_-_7145106 0.154 ENST00000577035.1
GABARAP
GABA(A) receptor-associated protein
chr12_-_54779511 0.153 ENST00000551109.1
ENST00000546970.1
ZNF385A

zinc finger protein 385A

chr17_-_39093672 0.152 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23


keratin 23 (histone deacetylase inducible)


chr5_-_64777685 0.151 ENST00000536360.1
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr15_-_52587945 0.151 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr15_+_43985725 0.150 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr14_-_21562648 0.150 ENST00000555270.1
ZNF219
zinc finger protein 219
chr16_+_1128781 0.149 ENST00000293897.4
ENST00000562758.1
SSTR5

somatostatin receptor 5

chr2_-_42160486 0.148 ENST00000427054.1
AC104654.2
AC104654.2
chr15_-_50411412 0.148 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr17_-_1389419 0.148 ENST00000575158.1
MYO1C
myosin IC
chr14_+_72052983 0.145 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr17_+_79495397 0.145 ENST00000417245.2
ENST00000334850.7
FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chr6_+_152011628 0.145 ENST00000404742.1
ENST00000440973.1
ESR1

estrogen receptor 1

chr11_-_88070920 0.144 ENST00000524463.1
ENST00000227266.5
CTSC

cathepsin C

chr16_+_19183671 0.143 ENST00000562711.2
SYT17
synaptotagmin XVII
chr7_+_30185406 0.142 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr6_-_13290684 0.141 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr3_-_112360116 0.141 ENST00000206423.3
ENST00000439685.2
CCDC80

coiled-coil domain containing 80

chr6_-_134495992 0.140 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1


serum/glucocorticoid regulated kinase 1


chr1_-_160990886 0.139 ENST00000537746.1
F11R
F11 receptor
chr7_+_56032652 0.138 ENST00000437587.1
GBAS
glioblastoma amplified sequence
chr12_-_7244469 0.138 ENST00000538050.1
ENST00000536053.2
C1R

complement component 1, r subcomponent

chr17_+_27047570 0.137 ENST00000472628.1
ENST00000578181.1
RPL23A

ribosomal protein L23a

chr6_+_106546808 0.136 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_46620676 0.134 ENST00000371347.5
ENST00000411689.2
SLC25A27

solute carrier family 25, member 27

chr5_+_148960931 0.133 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr5_+_66124590 0.132 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr14_+_21538517 0.132 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr14_+_24837226 0.132 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4




nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4




chr14_+_74318513 0.132 ENST00000555228.1
ENST00000555661.1
PTGR2

prostaglandin reductase 2

chr11_+_9482551 0.129 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
ZNF143




zinc finger protein 143




chr8_-_95449155 0.129 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr19_+_7599597 0.129 ENST00000414982.3
ENST00000450331.3
PNPLA6

patatin-like phospholipase domain containing 6

chr14_+_74318611 0.128 ENST00000555976.1
ENST00000267568.4
PTGR2

prostaglandin reductase 2

chr16_-_46797149 0.126 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr12_+_38710555 0.126 ENST00000551464.1
ALG10B
ALG10B, alpha-1,2-glucosyltransferase
chr6_+_106534192 0.125 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chrX_+_154254960 0.125 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr1_+_215747118 0.124 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr9_+_137987825 0.121 ENST00000545657.1
OLFM1
olfactomedin 1
chr11_-_114271139 0.121 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr12_+_54393880 0.121 ENST00000303450.4
HOXC9
homeobox C9
chr14_-_76447336 0.121 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr16_-_85969774 0.121 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr11_-_8892900 0.119 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5






suppression of tumorigenicity 5






chr16_+_3254247 0.119 ENST00000304646.2
OR1F1
olfactory receptor, family 1, subfamily F, member 1
chr11_-_88070896 0.118 ENST00000529974.1
ENST00000527018.1
CTSC

cathepsin C

chr5_+_38846101 0.117 ENST00000274276.3
OSMR
oncostatin M receptor
chr1_-_161337662 0.116 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr19_+_7599792 0.116 ENST00000600942.1
ENST00000593924.1
PNPLA6

patatin-like phospholipase domain containing 6

chr15_-_90892669 0.115 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr11_+_11863579 0.115 ENST00000399455.2
USP47
ubiquitin specific peptidase 47
chr11_+_112041253 0.115 ENST00000532612.1
AP002884.3
AP002884.3
chr4_-_100356551 0.114 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_-_23891693 0.113 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_8892464 0.113 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5




suppression of tumorigenicity 5




chr8_+_81397846 0.112 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr3_+_164924716 0.111 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2

RP11-85M11.2

chr16_+_30907927 0.111 ENST00000279804.2
ENST00000395019.3
CTF1

cardiotrophin 1

chr4_-_186661365 0.110 ENST00000452351.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_111630451 0.109 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_+_100428316 0.109 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG


TRK-fused gene


chr11_+_11863500 0.108 ENST00000527733.1
ENST00000539466.1
USP47

ubiquitin specific peptidase 47

chr7_+_120629085 0.107 ENST00000428526.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr3_-_111852128 0.106 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr5_+_52856456 0.104 ENST00000296684.5
ENST00000506765.1
NDUFS4

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

chr8_-_145754428 0.104 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82


chromosome 8 open reading frame 82


chr11_+_7626950 0.103 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_-_6484715 0.103 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr8_-_80680078 0.102 ENST00000337919.5
ENST00000354724.3
HEY1

hes-related family bHLH transcription factor with YRPW motif 1

chr12_-_57037284 0.102 ENST00000551570.1
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chrX_+_133941250 0.101 ENST00000445123.1
FAM122C
family with sequence similarity 122C
chr11_+_9482512 0.100 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143




zinc finger protein 143




chr6_-_134639042 0.099 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_56212505 0.099 ENST00000505210.1
SRD5A3
steroid 5 alpha-reductase 3
chr17_-_7387524 0.098 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr11_-_111794446 0.098 ENST00000527950.1
CRYAB
crystallin, alpha B
chr1_+_150521876 0.097 ENST00000369041.5
ENST00000271643.4
ENST00000538795.1
ADAMTSL4

AL356356.1
ADAMTS-like 4

Protein LOC100996516
chr3_-_113415441 0.096 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr17_+_73452545 0.096 ENST00000314256.7
KIAA0195
KIAA0195
chr20_+_12989895 0.095 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr17_+_53016208 0.095 ENST00000574318.1
TOM1L1
target of myb1 (chicken)-like 1
chr17_-_74528128 0.095 ENST00000590175.1
CYGB
cytoglobin
chr3_+_140947563 0.095 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr7_+_44663908 0.094 ENST00000543843.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr11_+_61595572 0.093 ENST00000517312.1
FADS2
fatty acid desaturase 2
chr17_+_27895609 0.093 ENST00000581411.2
ENST00000301057.7
TP53I13

tumor protein p53 inducible protein 13

chr12_+_122459757 0.092 ENST00000261822.4
BCL7A
B-cell CLL/lymphoma 7A
chr6_-_53530474 0.092 ENST00000370905.3
KLHL31
kelch-like family member 31
chr22_-_39640756 0.091 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr12_-_9268707 0.090 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr21_-_43771226 0.090 ENST00000291526.4
TFF2
trefoil factor 2
chrX_+_22056165 0.089 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr20_-_32262165 0.088 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
NECAB3



N-terminal EF-hand calcium binding protein 3



chr1_-_1334685 0.088 ENST00000400809.3
ENST00000408918.4
CCNL2

cyclin L2

chr7_-_156803329 0.088 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr1_-_244006528 0.088 ENST00000336199.5
ENST00000263826.5
AKT3

v-akt murine thymoma viral oncogene homolog 3

chr16_+_53412368 0.088 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr7_+_30185496 0.087 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr9_+_139702363 0.086 ENST00000371663.4
ENST00000371671.4
ENST00000311502.7
RABL6


RAB, member RAS oncogene family-like 6


chr4_-_100356291 0.086 ENST00000476959.1
ENST00000482593.1
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 2.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 2.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.6 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.0 0.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.3 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.0 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.0 GO:0042495 toll-like receptor 1 signaling pathway(GO:0034130) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.0 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0097001 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis