ISMARA results: MLX_USF2_USF1

Motif ID: MLX_USF2_USF1_PAX2

Z-value: 1.191

Transcription factors associated with MLX_USF2_USF1_PAX2:

Gene Symbol	Entrez ID	Gene Name
MLX	ENSG00000108788.7	MLX
PAX2	ENSG00000075891.17	PAX2
USF1	ENSG00000158773.10	USF1
USF2	ENSG00000105698.11	USF2

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
USF1	hg19_v2_chr1_-_161015663_161015694	0.79	1.2e-02	Click!
MLX	hg19_v2_chr17_+_40719073_40719092	0.21	5.8e-01	Click!
USF2	hg19_v2_chr19_+_35759824_35759891	-0.16	6.8e-01	Click!

Sorted Z-values for motif MLX_USF2_USF1_PAX2

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_23728198	2.795	ENST00000376495.3	OTUD1	OTU domain containing 1
chr13_+_49684445	2.181	ENST00000398316.3	FNDC3A	fibronectin type III domain containing 3A
chr1_+_154193325	2.108	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L	ubiquitin associated protein 2-like
chr1_-_183538319	1.910	ENST00000420553.1 ENST00000419402.1	NCF2	neutrophil cytosolic factor 2
chr19_+_45504688	1.897	ENST00000221452.8 ENST00000540120.1 ENST00000505236.1	RELB	v-rel avian reticuloendotheliosis viral oncogene homolog B
chr12_-_49463753	1.654	ENST00000301068.6	RHEBL1	Ras homolog enriched in brain like 1
chr1_+_154193643	1.573	ENST00000456325.1	UBAP2L	ubiquitin associated protein 2-like
chr12_-_49463620	1.488	ENST00000550675.1	RHEBL1	Ras homolog enriched in brain like 1
chr9_-_34048873	1.292	ENST00000449054.1 ENST00000379239.4 ENST00000539807.1 ENST00000379238.1 ENST00000418786.2 ENST00000360802.1 ENST00000412543.1	UBAP2	ubiquitin associated protein 2
chr15_+_41913690	1.208	ENST00000563576.1	MGA	MGA, MAX dimerization protein
chr14_-_81687575	1.172	ENST00000434192.2	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr6_+_138188378	1.163	ENST00000420009.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr15_-_73925651	1.121	ENST00000545878.1 ENST00000287226.8 ENST00000345330.4	NPTN	neuroplastin
chr8_+_94929110	1.080	ENST00000520728.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_-_132299290	1.070	ENST00000378595.3	AFF4	AF4/FMR2 family, member 4
chr6_+_138188551	1.056	ENST00000237289.4 ENST00000433680.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr12_-_90103077	1.053	ENST00000551310.1	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr15_-_73925575	1.051	ENST00000562924.1 ENST00000563691.1 ENST00000565325.1 ENST00000542234.1	NPTN	neuroplastin
chr8_+_94929077	1.044	ENST00000297598.4 ENST00000520614.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr16_+_31044413	1.025	ENST00000394998.1	STX4	syntaxin 4
chr8_+_94929168	1.009	ENST00000518107.1 ENST00000396200.3	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chrX_+_55744228	0.998	ENST00000262850.7	RRAGB	Ras-related GTP binding B
chr8_+_94929273	0.937	ENST00000518573.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_-_168006324	0.931	ENST00000522176.1	PANK3	pantothenate kinase 3
chrX_+_55744166	0.915	ENST00000374941.4 ENST00000414239.1	RRAGB	Ras-related GTP binding B
chr18_+_77867177	0.891	ENST00000560752.1	ADNP2	ADNP homeobox 2
chr16_+_31044812	0.874	ENST00000313843.3	STX4	syntaxin 4
chr14_+_74551650	0.872	ENST00000554938.1	LIN52	lin-52 homolog (C. elegans)
chr12_-_58146048	0.862	ENST00000547281.1 ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6	CDK4	cyclin-dependent kinase 4
chr12_-_58146128	0.857	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4	cyclin-dependent kinase 4
chr15_+_89181974	0.847	ENST00000306072.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr2_+_233562015	0.832	ENST00000427233.1 ENST00000373566.3 ENST00000373563.4 ENST00000428883.1 ENST00000456491.1 ENST00000409480.1 ENST00000421433.1 ENST00000425040.1 ENST00000430720.1 ENST00000409547.1 ENST00000423659.1 ENST00000409196.3 ENST00000409451.3 ENST00000429187.1 ENST00000440945.1	GIGYF2	GRB10 interacting GYF protein 2
chr15_+_89182178	0.831	ENST00000559876.1	ISG20	interferon stimulated exonuclease gene 20kDa
chrX_+_44732757	0.814	ENST00000377967.4 ENST00000536777.1 ENST00000382899.4 ENST00000543216.1	KDM6A	lysine (K)-specific demethylase 6A
chr18_+_56807096	0.813	ENST00000588875.1	SEC11C	SEC11 homolog C (S. cerevisiae)
chr9_+_6758024	0.812	ENST00000442236.2	KDM4C	lysine (K)-specific demethylase 4C
chr8_+_120220561	0.805	ENST00000276681.6	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr18_+_56806701	0.798	ENST00000587834.1	SEC11C	SEC11 homolog C (S. cerevisiae)
chr3_-_170626418	0.791	ENST00000474096.1 ENST00000295822.2	EIF5A2	eukaryotic translation initiation factor 5A2
chr4_+_38665810	0.783	ENST00000261438.5 ENST00000514033.1	KLF3	Kruppel-like factor 3 (basic)
chr2_-_133427767	0.783	ENST00000397463.2	LYPD1	LY6/PLAUR domain containing 1
chr12_+_53645870	0.781	ENST00000329548.4	MFSD5	major facilitator superfamily domain containing 5
chr19_-_43032532	0.781	ENST00000403461.1 ENST00000352591.5 ENST00000358394.3 ENST00000403444.3 ENST00000308072.4 ENST00000599389.1 ENST00000351134.3 ENST00000161559.6	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr9_+_131709966	0.777	ENST00000372577.2	NUP188	nucleoporin 188kDa
chr1_-_241520385	0.772	ENST00000366564.1	RGS7	regulator of G-protein signaling 7
chr10_+_46222648	0.766	ENST00000336378.4 ENST00000540872.1 ENST00000537517.1 ENST00000374362.2 ENST00000359860.4 ENST00000420848.1	FAM21C	family with sequence similarity 21, member C
chr16_-_58718611	0.760	ENST00000564100.1 ENST00000570101.1	SLC38A7	solute carrier family 38, member 7
chr1_+_150254936	0.734	ENST00000447007.1 ENST00000369095.1 ENST00000369094.1	C1orf51	chromosome 1 open reading frame 51
chr12_+_101673872	0.733	ENST00000261637.4	UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)
chr14_-_81687197	0.733	ENST00000553612.1	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr1_-_145610869	0.717	ENST00000334163.3 ENST00000369294.1	POLR3C	polymerase (RNA) III (DNA directed) polypeptide C (62kD)
chr21_-_35987438	0.696	ENST00000313806.4	RCAN1	regulator of calcineurin 1
chr14_-_20929624	0.685	ENST00000398020.4 ENST00000250489.4	TMEM55B	transmembrane protein 55B
chr1_-_241520525	0.684	ENST00000366565.1	RGS7	regulator of G-protein signaling 7
chr16_-_58718638	0.684	ENST00000562397.1 ENST00000564010.1 ENST00000570214.1 ENST00000563196.1	SLC38A7	solute carrier family 38, member 7
chr9_+_6758109	0.682	ENST00000536108.1	KDM4C	lysine (K)-specific demethylase 4C
chr15_+_89182156	0.678	ENST00000379224.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr6_+_42018251	0.675	ENST00000372978.3 ENST00000494547.1 ENST00000456846.2 ENST00000372982.4 ENST00000472818.1 ENST00000372977.3	TAF8	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr21_-_43430440	0.672	ENST00000398505.3 ENST00000310826.5 ENST00000449949.1 ENST00000398499.1 ENST00000398497.2 ENST00000398511.3	ZBTB21	zinc finger and BTB domain containing 21
chr9_-_37576226	0.666	ENST00000432825.2	FBXO10	F-box protein 10
chr10_+_51827648	0.661	ENST00000351071.6 ENST00000314664.7 ENST00000282633.5	FAM21A	family with sequence similarity 21, member A
chr12_-_65153175	0.641	ENST00000543646.1 ENST00000542058.1 ENST00000258145.3	GNS	glucosamine (N-acetyl)-6-sulfatase
chr3_+_112280857	0.636	ENST00000492406.1 ENST00000468642.1	SLC35A5	solute carrier family 35, member A5
chrX_+_129040122	0.635	ENST00000394422.3 ENST00000371051.5	UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr3_+_148847371	0.634	ENST00000296051.2 ENST00000460120.1	HPS3	Hermansky-Pudlak syndrome 3
chr19_+_13049413	0.631	ENST00000316448.5 ENST00000588454.1	CALR	calreticulin
chr2_+_46926326	0.626	ENST00000394861.2	SOCS5	suppressor of cytokine signaling 5
chr16_+_81812863	0.623	ENST00000359376.3	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_154531095	0.623	ENST00000292211.4	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr2_+_113403434	0.620	ENST00000272542.3	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr9_+_115913222	0.610	ENST00000259392.3	SLC31A2	solute carrier family 31 (copper transporter), member 2
chr1_+_11866270	0.609	ENST00000376497.3 ENST00000376487.3 ENST00000376496.3	CLCN6	chloride channel, voltage-sensitive 6
chrX_+_129040094	0.603	ENST00000425117.2	UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr9_+_6757634	0.598	ENST00000543771.1 ENST00000401787.3 ENST00000381306.3 ENST00000381309.3	KDM4C	lysine (K)-specific demethylase 4C
chr2_-_232328867	0.598	ENST00000453992.1 ENST00000417652.1 ENST00000454824.1	NCL	nucleolin
chr1_-_113498616	0.593	ENST00000433570.4 ENST00000538576.1 ENST00000458229.1	SLC16A1	solute carrier family 16 (monocarboxylate transporter), member 1
chr3_-_194207388	0.591	ENST00000457986.1	ATP13A3	ATPase type 13A3
chr12_-_90102594	0.575	ENST00000428670.3	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr4_+_76439095	0.571	ENST00000506261.1	THAP6	THAP domain containing 6
chr10_+_104154229	0.566	ENST00000428099.1 ENST00000369966.3	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_76439483	0.564	ENST00000380840.2 ENST00000513257.1 ENST00000507014.1	RCHY1	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr3_-_169899504	0.562	ENST00000474275.1 ENST00000484931.1 ENST00000494943.1 ENST00000497658.1 ENST00000465896.1 ENST00000475729.1 ENST00000495893.2 ENST00000481639.1 ENST00000467570.1 ENST00000466189.1	PHC3	polyhomeotic homolog 3 (Drosophila)
chr7_-_27135591	0.561	ENST00000343060.4 ENST00000355633.5	HOXA1	homeobox A1
chr3_+_5020801	0.559	ENST00000256495.3	BHLHE40	basic helix-loop-helix family, member e40
chr1_-_78148324	0.558	ENST00000370801.3 ENST00000433749.1	ZZZ3	zinc finger, ZZ-type containing 3
chr5_+_35852797	0.558	ENST00000508941.1	IL7R	interleukin 7 receptor
chr9_-_131709858	0.558	ENST00000372586.3	DOLK	dolichol kinase
chr6_+_127587755	0.554	ENST00000368314.1 ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1	RNF146	ring finger protein 146
chr5_-_131132658	0.550	ENST00000511848.1 ENST00000510461.1 ENST00000514667.1	FNIP1 CTC-432M15.3	folliculin interacting protein 1 Folliculin-interacting protein 1
chr2_+_208576259	0.546	ENST00000392209.3	CCNYL1	cyclin Y-like 1
chr13_+_42846272	0.540	ENST00000025301.2	AKAP11	A kinase (PRKA) anchor protein 11
chr10_-_46089939	0.539	ENST00000453980.3	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr11_+_65479702	0.535	ENST00000530446.1 ENST00000534104.1 ENST00000530605.1 ENST00000528198.1 ENST00000531880.1 ENST00000534650.1	KAT5	K(lysine) acetyltransferase 5
chr14_-_68283291	0.535	ENST00000555452.1 ENST00000347230.4	ZFYVE26	zinc finger, FYVE domain containing 26
chrX_+_118108601	0.534	ENST00000371628.3	LONRF3	LON peptidase N-terminal domain and ring finger 3
chr6_+_127588020	0.533	ENST00000309649.3 ENST00000610162.1 ENST00000610153.1 ENST00000608991.1 ENST00000480444.1	RNF146	ring finger protein 146
chr1_-_204329013	0.533	ENST00000272203.3 ENST00000414478.1	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr14_+_24630465	0.532	ENST00000557894.1 ENST00000559284.1 ENST00000560275.1	IRF9	interferon regulatory factor 9
chr4_+_75310851	0.528	ENST00000395748.3 ENST00000264487.2	AREG	amphiregulin
chr22_-_36903101	0.523	ENST00000397224.4	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr6_-_144329531	0.522	ENST00000429150.1 ENST00000392309.1 ENST00000416623.1 ENST00000392307.1	PLAGL1	pleiomorphic adenoma gene-like 1
chr1_+_22778337	0.521	ENST00000404138.1 ENST00000400239.2 ENST00000375647.4 ENST00000374651.4	ZBTB40	zinc finger and BTB domain containing 40
chrX_+_54466829	0.520	ENST00000375151.4	TSR2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr19_-_41256207	0.517	ENST00000598485.2 ENST00000470681.1 ENST00000339153.3 ENST00000598729.1	C19orf54	chromosome 19 open reading frame 54
chr4_-_76439596	0.516	ENST00000451788.1 ENST00000512706.1	RCHY1	ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr12_-_122751002	0.516	ENST00000267199.4	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr3_-_170626376	0.507	ENST00000487522.1 ENST00000474417.1	EIF5A2	eukaryotic translation initiation factor 5A2
chr2_+_220042933	0.501	ENST00000430297.2	FAM134A	family with sequence similarity 134, member A
chr11_-_71814422	0.500	ENST00000278671.5	LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr3_-_195163584	0.496	ENST00000439666.1	ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_-_35497233	0.494	ENST00000415531.1	ZMYM6	zinc finger, MYM-type 6
chr6_+_30689401	0.493	ENST00000396389.1 ENST00000396384.1	TUBB	tubulin, beta class I
chr16_+_5083950	0.492	ENST00000588623.1	ALG1	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr11_-_71814276	0.490	ENST00000538404.1 ENST00000535107.1 ENST00000545249.1	LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr7_+_36429424	0.489	ENST00000396068.2	ANLN	anillin, actin binding protein
chr1_+_100503643	0.489	ENST00000370152.3	HIAT1	hippocampus abundant transcript 1
chr1_+_222885884	0.488	ENST00000340934.5	BROX	BRO1 domain and CAAX motif containing
chr12_-_76953513	0.485	ENST00000547540.1	OSBPL8	oxysterol binding protein-like 8
chr8_+_71581565	0.482	ENST00000408926.3 ENST00000520030.1	XKR9	XK, Kell blood group complex subunit-related family, member 9
chr19_-_40854417	0.480	ENST00000582006.1 ENST00000582783.1	C19orf47	chromosome 19 open reading frame 47
chr2_-_26101314	0.478	ENST00000336112.4 ENST00000272341.4	ASXL2	additional sex combs like 2 (Drosophila)
chr2_+_208576355	0.475	ENST00000420822.1 ENST00000295414.3 ENST00000339882.5	CCNYL1	cyclin Y-like 1
chr5_-_132299313	0.471	ENST00000265343.5	AFF4	AF4/FMR2 family, member 4
chr1_+_15853308	0.470	ENST00000375838.1 ENST00000375847.3 ENST00000375849.1	DNAJC16	DnaJ (Hsp40) homolog, subfamily C, member 16
chr3_+_133292851	0.468	ENST00000503932.1	CDV3	CDV3 homolog (mouse)
chr11_+_101981423	0.467	ENST00000531439.1	YAP1	Yes-associated protein 1
chr4_-_99850243	0.467	ENST00000280892.6 ENST00000511644.1 ENST00000504432.1 ENST00000505992.1	EIF4E	eukaryotic translation initiation factor 4E
chrX_-_119693745	0.467	ENST00000371323.2	CUL4B	cullin 4B
chr6_+_138188351	0.465	ENST00000421450.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr1_+_40420802	0.465	ENST00000372811.5 ENST00000420632.2 ENST00000434861.1 ENST00000372809.5	MFSD2A	major facilitator superfamily domain containing 2A
chr12_+_14518598	0.464	ENST00000261168.4 ENST00000538511.1 ENST00000545723.1 ENST00000543189.1 ENST00000536444.1	ATF7IP	activating transcription factor 7 interacting protein
chr1_-_27226928	0.464	ENST00000361720.5	GPATCH3	G patch domain containing 3
chr1_+_145611010	0.462	ENST00000369291.5	RNF115	ring finger protein 115
chr16_-_23160591	0.457	ENST00000219689.7	USP31	ubiquitin specific peptidase 31
chr4_-_83934078	0.456	ENST00000505397.1	LIN54	lin-54 homolog (C. elegans)
chr5_+_150827143	0.454	ENST00000243389.3 ENST00000517945.1 ENST00000521925.1	SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1
chr22_+_41777927	0.450	ENST00000266304.4	TEF	thyrotrophic embryonic factor
chr7_+_36429409	0.449	ENST00000265748.2	ANLN	anillin, actin binding protein
chr1_-_100643765	0.449	ENST00000370137.1 ENST00000370138.1 ENST00000342895.3	LRRC39	leucine rich repeat containing 39
chr1_-_207226313	0.447	ENST00000367084.1	YOD1	YOD1 deubiquitinase
chr3_+_184032419	0.443	ENST00000352767.3 ENST00000427141.2	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr16_+_4897632	0.442	ENST00000262376.6	UBN1	ubinuclein 1
chr1_-_157108130	0.441	ENST00000368192.4	ETV3	ets variant 3
chr18_+_32621324	0.440	ENST00000300249.5 ENST00000538170.2 ENST00000588910.1	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr1_-_150738261	0.434	ENST00000448301.2 ENST00000368985.3	CTSS	cathepsin S
chr15_-_34610962	0.434	ENST00000290209.5	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6
chr20_+_37590942	0.433	ENST00000373325.2 ENST00000252011.3 ENST00000373323.4	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr4_+_76439649	0.433	ENST00000507557.1	THAP6	THAP domain containing 6
chrX_+_41192595	0.429	ENST00000399959.2	DDX3X	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr8_-_54755459	0.429	ENST00000524234.1 ENST00000521275.1 ENST00000396774.2	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr4_-_83933999	0.428	ENST00000510557.1	LIN54	lin-54 homolog (C. elegans)
chr10_+_70480963	0.427	ENST00000265872.6 ENST00000535016.1 ENST00000538031.1 ENST00000543719.1 ENST00000539539.1 ENST00000543225.1 ENST00000536012.1 ENST00000494903.2	CCAR1	cell division cycle and apoptosis regulator 1
chr8_-_54755789	0.427	ENST00000359530.2	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr6_-_144329384	0.426	ENST00000417959.2	PLAGL1	pleiomorphic adenoma gene-like 1
chr5_-_133706695	0.426	ENST00000521755.1 ENST00000523054.1 ENST00000435240.2 ENST00000609654.1 ENST00000536186.1 ENST00000609383.1	CDKL3	cyclin-dependent kinase-like 3
chr10_+_102672712	0.426	ENST00000370271.3 ENST00000370269.3 ENST00000609386.1	FAM178A	family with sequence similarity 178, member A
chr5_-_150138551	0.422	ENST00000446090.2 ENST00000447998.2	DCTN4	dynactin 4 (p62)
chrX_-_102510045	0.420	ENST00000360000.4	TCEAL8	transcription elongation factor A (SII)-like 8
chr5_-_131132614	0.420	ENST00000307968.7 ENST00000307954.8	FNIP1	folliculin interacting protein 1
chr11_-_85779971	0.418	ENST00000393346.3	PICALM	phosphatidylinositol binding clathrin assembly protein
chr8_-_82754427	0.414	ENST00000353788.4 ENST00000520618.1 ENST00000518183.1 ENST00000396330.2 ENST00000519119.1 ENST00000345957.4	SNX16	sorting nexin 16
chr14_-_20923195	0.413	ENST00000206542.4	OSGEP	O-sialoglycoprotein endopeptidase
chr18_+_32556892	0.413	ENST00000591734.1 ENST00000413393.1 ENST00000589180.1 ENST00000587359.1	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr5_-_150138246	0.412	ENST00000518015.1	DCTN4	dynactin 4 (p62)
chr1_+_173837488	0.410	ENST00000427304.1 ENST00000432989.1 ENST00000367702.1	ZBTB37	zinc finger and BTB domain containing 37
chr11_+_65479462	0.409	ENST00000377046.3 ENST00000352980.4 ENST00000341318.4	KAT5	K(lysine) acetyltransferase 5
chrX_-_102510126	0.409	ENST00000372685.3	TCEAL8	transcription elongation factor A (SII)-like 8
chrX_+_49832231	0.408	ENST00000376108.3	CLCN5	chloride channel, voltage-sensitive 5
chr2_-_120980939	0.407	ENST00000426077.2	TMEM185B	transmembrane protein 185B
chr22_-_39096981	0.407	ENST00000427389.1	JOSD1	Josephin domain containing 1
chr12_+_105501487	0.407	ENST00000332180.5	KIAA1033	KIAA1033
chr5_-_176924562	0.407	ENST00000359895.2 ENST00000355572.2 ENST00000355841.2 ENST00000393551.1 ENST00000505074.1 ENST00000356618.4 ENST00000393546.4	PDLIM7	PDZ and LIM domain 7 (enigma)
chr1_-_3816779	0.404	ENST00000361605.3	C1orf174	chromosome 1 open reading frame 174
chr12_-_76953573	0.403	ENST00000549646.1 ENST00000550628.1 ENST00000553139.1 ENST00000261183.3 ENST00000393250.4	OSBPL8	oxysterol binding protein-like 8
chr5_-_168006591	0.401	ENST00000239231.6	PANK3	pantothenate kinase 3
chr12_-_114404111	0.399	ENST00000545145.2 ENST00000392561.3 ENST00000261741.5	RBM19	RNA binding motif protein 19
chr19_-_36545128	0.396	ENST00000538849.1	THAP8	THAP domain containing 8
chr9_-_103115135	0.395	ENST00000537512.1	TEX10	testis expressed 10
chr2_-_217236750	0.392	ENST00000273067.4	MARCH4	membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr22_-_39096925	0.391	ENST00000456626.1 ENST00000412832.1	JOSD1	Josephin domain containing 1
chr2_+_46926048	0.386	ENST00000306503.5	SOCS5	suppressor of cytokine signaling 5
chrX_+_118108571	0.385	ENST00000304778.7	LONRF3	LON peptidase N-terminal domain and ring finger 3
chr6_+_32811885	0.384	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 PSMB9	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_113498943	0.383	ENST00000369626.3	SLC16A1	solute carrier family 16 (monocarboxylate transporter), member 1
chr16_+_57220049	0.382	ENST00000562439.1	RSPRY1	ring finger and SPRY domain containing 1
chr12_-_40499661	0.382	ENST00000280871.4	SLC2A13	solute carrier family 2 (facilitated glucose transporter), member 13
chr2_-_198364581	0.382	ENST00000428204.1	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr20_+_58515417	0.382	ENST00000360816.3	FAM217B	family with sequence similarity 217, member B
chr19_-_44160768	0.381	ENST00000593447.1	PLAUR	plasminogen activator, urokinase receptor
chr9_-_103115185	0.380	ENST00000374902.4	TEX10	testis expressed 10
chr17_+_7476136	0.380	ENST00000582169.1 ENST00000578754.1 ENST00000578495.1 ENST00000293831.8 ENST00000380512.5 ENST00000585024.1 ENST00000583802.1 ENST00000577269.1 ENST00000584784.1 ENST00000582746.1	EIF4A1	eukaryotic translation initiation factor 4A1
chr8_+_38243967	0.379	ENST00000524874.1 ENST00000379957.4 ENST00000523983.2	LETM2	leucine zipper-EF-hand containing transmembrane protein 2
chr1_-_78149041	0.378	ENST00000414381.1 ENST00000370798.1	ZZZ3	zinc finger, ZZ-type containing 3
chr12_+_57984943	0.375	ENST00000422156.3	PIP4K2C	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr4_+_75311019	0.373	ENST00000502307.1	AREG	amphiregulin
chr5_+_94890778	0.371	ENST00000380009.4	ARSK	arylsulfatase family, member K
chr22_-_36903069	0.371	ENST00000216187.6 ENST00000423980.1	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr17_+_17876127	0.370	ENST00000582416.1 ENST00000313838.8 ENST00000411504.2 ENST00000581264.1 ENST00000399187.1 ENST00000479684.2 ENST00000584166.1 ENST00000585108.1 ENST00000399182.1 ENST00000579977.1	LRRC48	leucine rich repeat containing 48
chr20_+_47538357	0.370	ENST00000371917.4	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr12_-_121342170	0.368	ENST00000353487.2	SPPL3	signal peptide peptidase like 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0070429	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.6	1.9	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.6	4.0	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.5	2.2	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.5	2.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.3	1.0	GO:0051780	mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3	0.9	GO:0031106	septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.3	0.6	GO:0002316	follicular B cell differentiation(GO:0002316)
0.3	1.4	GO:0015817	histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.3	0.8	GO:0002856	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.2	0.7	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2	1.0	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2	0.9	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.2	4.0	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2	0.6	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2	1.9	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.2	1.6	GO:1990034	cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2	1.9	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2	0.5	GO:0045041	B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.1	GO:0061300	cerebellum vasculature development(GO:0061300)
0.1	0.6	GO:0002268	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1	0.5	GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1	0.8	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	1.5	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	1.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.9	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	1.0	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1	0.6	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.1	0.5	GO:1901804	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1	0.4	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of fibroblast growth factor production(GO:0090271) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.9	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	0.6	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.4	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1	0.5	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.1	0.3	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.1	0.2	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1	0.3	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.1	0.4	GO:0010157	response to chlorate(GO:0010157)
0.1	0.3	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.9	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1	0.4	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	0.7	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.1	0.3	GO:1904585	response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1	0.4	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.3	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.1	0.2	GO:0036451	cap mRNA methylation(GO:0036451)
0.1	2.0	GO:0060009	Sertoli cell development(GO:0060009)
0.1	0.9	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.6	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.2	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.1	0.5	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.2	GO:0003165	Purkinje myocyte development(GO:0003165)
0.1	0.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	1.1	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	0.5	GO:0015798	myo-inositol transport(GO:0015798)
0.1	0.8	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	1.6	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	0.8	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1	0.4	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1	0.3	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.2	GO:0001207	histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.5	GO:0006824	cobalt ion transport(GO:0006824)
0.1	2.9	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.4	GO:0061724	lipophagy(GO:0061724)
0.1	0.5	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.1	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	0.6	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1	0.4	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.4	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1	0.1	GO:0060996	dendritic spine development(GO:0060996)
0.1	0.3	GO:0071344	diphosphate metabolic process(GO:0071344)
0.1	0.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.5	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.5	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1	0.2	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	0.2	GO:0046462	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1	0.5	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.6	GO:0021603	cranial nerve formation(GO:0021603) semicircular canal morphogenesis(GO:0048752)
0.1	0.2	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	1.7	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.3	GO:0090649	rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1	0.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.8	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.4	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952)
0.1	0.1	GO:0032764	negative regulation of mast cell cytokine production(GO:0032764)
0.1	1.9	GO:0042554	superoxide anion generation(GO:0042554)
0.1	0.2	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1	0.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	0.9	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.6	GO:0070459	prolactin secretion(GO:0070459)
0.1	0.1	GO:2000506	negative regulation of energy homeostasis(GO:2000506)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0018194	N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0	0.5	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.3	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.0	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.2	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0	0.2	GO:0071400	cellular response to oleic acid(GO:0071400)
0.0	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.6	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0006043	glucosamine catabolic process(GO:0006043)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999)
0.0	0.2	GO:0003094	glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0	1.0	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.2	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.0	0.4	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0	0.2	GO:0031627	telomeric loop formation(GO:0031627)
0.0	0.4	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
0.0	0.1	GO:0000961	negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0	0.7	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.6	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.5	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.3	GO:2000782	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0	0.1	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0	0.2	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.0	0.4	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.4	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.4	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.0	0.9	GO:0007097	nuclear migration(GO:0007097)
0.0	0.7	GO:0060242	contact inhibition(GO:0060242)
0.0	0.7	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.6	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	1.0	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.4	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0036369	transcription factor catabolic process(GO:0036369)
0.0	0.6	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.0	0.2	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.0	0.1	GO:0002877	acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.0	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.0	0.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.2	GO:0015888	thiamine transport(GO:0015888)
0.0	0.3	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.4	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.0	0.0	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0032900	negative regulation of neurotrophin production(GO:0032900)
0.0	0.1	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0	0.2	GO:0070417	cellular response to cold(GO:0070417)
0.0	0.1	GO:0072334	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0	0.3	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	0.3	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	1.1	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.1	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.2	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0	0.2	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.3	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.1	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.5	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.7	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.6	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.7	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:0042823	pyridoxal phosphate biosynthetic process(GO:0042823)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.2	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.2	GO:1901355	response to rapamycin(GO:1901355)
0.0	0.1	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0	0.2	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0072553	terminal button organization(GO:0072553)
0.0	0.4	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.2	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.2	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.8	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0072737	response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0	1.0	GO:0030220	platelet formation(GO:0030220)
0.0	0.1	GO:2000619	negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.5	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.9	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.7	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	1.3	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.0	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	0.3	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.3	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.7	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.3	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0015886	heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0	0.3	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.4	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.0	0.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:0032240	negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.8	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.0	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.0	0.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.0	0.1	GO:1904562	phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0	0.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	2.8	GO:0031929	TOR signaling(GO:0031929)
0.0	0.7	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.1	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0	0.1	GO:1902910	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of hair follicle maturation(GO:0048817) negative regulation of catagen(GO:0051796) negative regulation of hair follicle development(GO:0051799) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0	0.3	GO:0014029	neural crest formation(GO:0014029)
0.0	0.4	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0015862	uridine transport(GO:0015862)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.7	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.7	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.0	GO:1902908	regulation of melanosome transport(GO:1902908)
0.0	0.1	GO:1990569	UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0	0.2	GO:2001140	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0	0.3	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0043686	co-translational protein modification(GO:0043686)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	2.6	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.7	GO:0046856	phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.3	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.2	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035) positive regulation of endocytic recycling(GO:2001137)
0.0	0.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0033123	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0	0.2	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.3	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.2	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0033866	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.0	0.1	GO:0009052	D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:1902741	type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0	0.1	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.3	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.0	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.2	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.3	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.1	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.6	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.8	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.0	0.1	GO:0039506	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0	0.1	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0035646	endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0	0.1	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.1	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.7	GO:0030317	sperm motility(GO:0030317)
0.0	0.2	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.7	GO:0007588	excretion(GO:0007588)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.5	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.9	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.0	GO:0070778	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:1902044	Fas signaling pathway(GO:0036337) regulation of Fas signaling pathway(GO:1902044)
0.0	0.2	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.2	GO:0034969	histone arginine methylation(GO:0034969)
0.0	0.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:1990131	Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	1.5	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	4.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	0.8	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	2.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	1.7	GO:0005787	signal peptidase complex(GO:0005787)
0.2	1.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	1.0	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2	1.0	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.7	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.1	1.9	GO:0000322	storage vacuole(GO:0000322)
0.1	0.9	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	2.2	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.8	GO:1990635	proximal dendrite(GO:1990635)
0.1	1.9	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.4	GO:0032279	asymmetric synapse(GO:0032279)
0.1	0.4	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1	0.4	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.7	GO:0031415	NatA complex(GO:0031415)
0.1	0.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.3	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	0.9	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.6	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	1.7	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	3.0	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	0.5	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.8	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.4	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	1.0	GO:0071439	clathrin complex(GO:0071439)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.1	2.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	0.4	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.0	0.4	GO:0061617	MICOS complex(GO:0061617)
0.0	0.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.8	GO:0005869	dynactin complex(GO:0005869)
0.0	1.4	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.6	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.7	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.5	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.2	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.0	0.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.7	GO:0005776	autophagosome(GO:0005776)
0.0	0.4	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.0	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	1.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	1.0	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.6	GO:0035102	PRC1 complex(GO:0035102)
0.0	2.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.0	0.5	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0	0.5	GO:0033391	chromatoid body(GO:0033391)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0031213	RSF complex(GO:0031213)
0.0	0.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.9	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.3	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.8	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0097362	MCM8-MCM9 complex(GO:0097362)
0.0	0.1	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	2.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0	1.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.0	0.6	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.1	GO:0070701	mucus layer(GO:0070701)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0035841	new growing cell tip(GO:0035841)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	2.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	1.4	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0008859	exoribonuclease II activity(GO:0008859)
0.6	4.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5	2.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.4	2.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3	1.0	GO:0015130	mevalonate transmembrane transporter activity(GO:0015130)
0.2	0.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	1.6	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	0.8	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.2	1.3	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	0.7	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	3.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.2	0.5	GO:0005365	myo-inositol transmembrane transporter activity(GO:0005365)
0.2	0.5	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1	0.6	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.1	1.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	1.5	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	2.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.9	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	0.4	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	0.3	GO:0047225	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1	0.3	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1	0.8	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.1	0.5	GO:0004348	glucosylceramidase activity(GO:0004348)
0.1	0.7	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1	0.7	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.1	1.9	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.5	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.2	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1	0.9	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	1.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.3	GO:0002134	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1	0.3	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1	0.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1	0.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	1.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.6	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.5	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	0.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.2	GO:0034736	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.4	GO:0005119	smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1	2.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.2	GO:0043849	Ras palmitoyltransferase activity(GO:0043849)
0.1	0.2	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.3	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	0.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.5	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.2	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.4	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	0.2	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.2	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.6	GO:0031386	protein tag(GO:0031386)
0.0	0.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
0.0	1.9	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	1.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0	0.5	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	1.7	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0043022	ribosome binding(GO:0043022)
0.0	0.5	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.2	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0	0.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.3	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	0.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.4	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.5	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	1.5	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.9	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	3.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.8	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.8	GO:0031005	filamin binding(GO:0031005)
0.0	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0050146	nucleoside phosphotransferase activity(GO:0050146)
0.0	0.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.1	GO:0003883	CTP synthase activity(GO:0003883)
0.0	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	1.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.8	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.8	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.7	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.0	0.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.1	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.8	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0004766	spermidine synthase activity(GO:0004766)
0.0	0.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	1.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0035242	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	1.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.7	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.8	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.6	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.0	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	0.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.2	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.4	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.4	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.4	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.0	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	0.2	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.0	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0	0.1	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0001160	transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.2	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.5	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.7	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0	0.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0	0.6	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.0	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	ST_TUMOR_NECROSIS_FACTOR_PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	SA_REG_CASCADE_OF_CYCLIN_EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	ST_TYPE_I_INTERFERON_PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	2.0	PID_INSULIN_GLUCOSE_PATHWAY	Insulin-mediated glucose transport
0.0	1.0	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway
0.0	0.3	SA_G2_AND_M_PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.0	PID_ERBB_NETWORK_PATHWAY	ErbB receptor signaling network
0.0	0.2	ST_JAK_STAT_PATHWAY	Jak-STAT Pathway
0.0	1.1	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	ST_INTERLEUKIN_4_PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	1.1	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	3.1	PID_RAC1_PATHWAY	RAC1 signaling pathway
0.0	0.1	PID_IL2_STAT5_PATHWAY	IL2 signaling events mediated by STAT5
0.0	3.3	PID_AR_PATHWAY	Coregulation of Androgen receptor activity
0.0	0.3	PID_TCR_RAS_PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.8	PID_IL12_2PATHWAY	IL12-mediated signaling events
0.0	1.5	PID_UPA_UPAR_PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	PID_WNT_CANONICAL_PATHWAY	Canonical Wnt signaling pathway
0.0	0.5	ST_ERK1_ERK2_MAPK_PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID_HDAC_CLASSII_PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	SA_TRKA_RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.9	PID_RB_1PATHWAY	Regulation of retinoblastoma protein
0.0	0.8	PID_NFAT_TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	ST_G_ALPHA_S_PATHWAY	G alpha s Pathway
0.0	0.5	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.4	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID_IL2_1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID_RET_PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.8	PID_IL4_2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.8	PID_SMAD2_3NUCLEAR_PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.7	PID_FAK_PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.6	ST_B_CELL_ANTIGEN_RECEPTOR	B Cell Antigen Receptor
0.0	0.4	PID_ERBB4_PATHWAY	ErbB4 signaling events
0.0	0.3	PID_MAPK_TRK_PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.6	PID_VEGFR1_2_PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID_AVB3_OPN_PATHWAY	Osteopontin-mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.0	REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.9	REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.4	REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.6	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.0	REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.0	REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	3.0	REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	0.8	REACTOME_RNA_POL_III_CHAIN_ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.6	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.0	REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.5	REACTOME_G0_AND_EARLY_G1	Genes involved in G0 and Early G1
0.0	0.5	REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	2.6	REACTOME_NOD1_2_SIGNALING_PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	2.9	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.7	REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.7	REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_	Genes involved in Cyclin E associated events during G1/S transition
0.0	1.3	REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	2.1	REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME_THE_NLRP3_INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME_IL_7_SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.4	REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME_SIGNAL_ATTENUATION	Genes involved in Signal attenuation
0.0	1.1	REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME_SIGNALING_BY_NOTCH4	Genes involved in Signaling by NOTCH4
0.0	1.8	REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.6	REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.8	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME_IL_6_SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.8	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME_P38MAPK_EVENTS	Genes involved in p38MAPK events
0.0	1.3	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.0	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.3	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.3	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.3	REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.4	REACTOME_METABOLISM_OF_NON_CODING_RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME_SIGNALING_BY_NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE	Genes involved in Beta-catenin phosphorylation cascade

ISMARA

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Motif ID: MLX_USF2_USF1_PAX2

Z-value: 1.191

Transcription factors associated with MLX_USF2_USF1_PAX2:

Activity-expression correlation:

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: