Motif ID: MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.398


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_1801994260.531.4e-01Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.166.8e-01Click!
MEOX2hg19_v2_chr7_-_15726296_15726437-0.117.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_87804815 1.089 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr6_-_116866773 0.569 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr16_+_53412368 0.528 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr18_-_33709268 0.456 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr6_-_116833500 0.413 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chrX_-_13835147 0.399 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr18_+_32173276 0.396 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr5_-_24645078 0.351 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr7_+_77428066 0.290 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr5_+_53751445 0.280 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr7_+_77428149 0.262 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr18_-_3220106 0.230 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr3_-_151034734 0.218 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr17_-_57229155 0.205 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr6_+_151042224 0.204 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr3_-_165555200 0.202 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr12_-_91546926 0.196 ENST00000550758.1
DCN
decorin
chr15_-_53002007 0.196 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr1_+_229440129 0.194 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr18_-_48351743 0.189 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr10_+_18549645 0.189 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_+_183065793 0.188 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr1_+_62439037 0.187 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr13_-_110438914 0.183 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr16_+_53133070 0.179 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr6_-_32908765 0.178 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_+_76330355 0.177 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr14_+_72052983 0.175 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr1_+_180601139 0.175 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr17_-_19015945 0.173 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chr17_+_19091325 0.171 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr4_-_186570679 0.166 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr12_-_74686314 0.162 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr5_+_137722255 0.161 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chrM_-_14670 0.159 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr3_+_151591422 0.158 ENST00000362032.5
SUCNR1
succinate receptor 1
chr10_-_69597810 0.157 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr4_-_187517928 0.155 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr5_+_136070614 0.155 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chrX_-_70326455 0.152 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr3_-_141747950 0.150 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_33061543 0.147 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr9_-_3469181 0.147 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr7_-_77427676 0.146 ENST00000257663.3
TMEM60
transmembrane protein 60
chr4_+_169418195 0.145 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr1_-_151762943 0.141 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr7_-_111032971 0.138 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_-_111794446 0.137 ENST00000527950.1
CRYAB
crystallin, alpha B
chr8_-_10512569 0.137 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr11_-_111649015 0.137 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chrX_-_106243451 0.136 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr6_+_26087509 0.136 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr11_-_129062093 0.135 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr6_-_66417107 0.133 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr8_-_18744528 0.133 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr5_-_126409159 0.132 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63



chromosome 5 open reading frame 63



chr10_+_18629628 0.131 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_+_48823975 0.130 ENST00000513969.1
ENST00000503728.1
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr12_-_51422017 0.129 ENST00000394904.3
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_-_61697862 0.128 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr9_-_23779367 0.128 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chrX_-_106243294 0.128 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr4_-_186696561 0.128 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr18_-_3219847 0.127 ENST00000261606.7
MYOM1
myomesin 1
chr2_-_216946500 0.127 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr6_+_153552455 0.127 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chrX_-_13835461 0.126 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr7_-_137028534 0.125 ENST00000348225.2
PTN
pleiotrophin
chr7_-_99716914 0.125 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_169013666 0.124 ENST00000359299.3
ANXA10
annexin A10
chr18_+_21572737 0.123 ENST00000304621.6
TTC39C
tetratricopeptide repeat domain 39C
chr6_-_109702885 0.121 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr3_-_191000172 0.121 ENST00000427544.2
UTS2B
urotensin 2B
chr16_+_12059091 0.120 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_+_169418255 0.117 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr8_-_128231299 0.117 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr11_-_111649074 0.116 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr18_-_33702078 0.114 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr2_+_158114051 0.114 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr10_-_71169031 0.113 ENST00000373307.1
TACR2
tachykinin receptor 2
chr3_-_46249878 0.113 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr7_-_80141328 0.112 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr12_-_54653313 0.112 ENST00000550411.1
ENST00000439541.2
CBX5

chromobox homolog 5

chr7_+_99717230 0.111 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr4_-_186696425 0.111 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr5_-_41794313 0.110 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr8_+_38831683 0.110 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr10_+_114710425 0.110 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr3_-_180397256 0.109 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr7_-_27169801 0.109 ENST00000511914.1
HOXA4
homeobox A4
chr15_+_80351910 0.108 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr7_-_137028498 0.108 ENST00000393083.2
PTN
pleiotrophin
chr16_-_46797149 0.108 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr10_-_69597828 0.106 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr2_-_55647057 0.106 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr4_+_41614909 0.105 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr17_-_72772425 0.104 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr8_-_17533838 0.103 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr4_+_139694701 0.102 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chrX_-_73512177 0.099 ENST00000603672.1
ENST00000418855.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr6_-_111804905 0.099 ENST00000358835.3
ENST00000435970.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr7_-_107642348 0.098 ENST00000393561.1
LAMB1
laminin, beta 1
chr18_+_71815743 0.097 ENST00000169551.6
ENST00000580087.1
TIMM21

translocase of inner mitochondrial membrane 21 homolog (yeast)

chr17_-_33390667 0.096 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr3_-_157221128 0.096 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr6_-_39693111 0.096 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chrX_+_123097014 0.095 ENST00000394478.1
STAG2
stromal antigen 2
chr12_+_20963632 0.094 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr14_+_101359265 0.094 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr2_-_207024233 0.094 ENST00000423725.1
ENST00000233190.6
NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

chr16_+_14280564 0.093 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr8_-_116504448 0.093 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr10_+_114710211 0.093 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr8_-_30706608 0.092 ENST00000256246.2
TEX15
testis expressed 15
chrX_+_22050546 0.091 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr4_-_186696515 0.090 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr15_-_88247083 0.088 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chrX_-_30871004 0.088 ENST00000378928.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr8_-_18541603 0.088 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr11_-_108093329 0.088 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr2_-_200320768 0.087 ENST00000428695.1
SATB2
SATB homeobox 2
chr6_+_72922590 0.087 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_89770582 0.087 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr4_-_89951028 0.087 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr11_+_28129795 0.086 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr9_-_5830768 0.085 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr7_-_99277610 0.085 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr14_-_70883708 0.084 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr13_-_88323514 0.083 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr11_+_77532233 0.083 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr14_-_64194745 0.083 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr17_+_41363854 0.083 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A




transmembrane protein 106A




chr2_-_183387064 0.083 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr11_-_31531121 0.082 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr1_-_45956822 0.081 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr12_-_25150373 0.081 ENST00000549828.1
C12orf77
chromosome 12 open reading frame 77
chr3_-_69129501 0.081 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3



ubiquitin-like modifier activating enzyme 3



chr8_-_112248400 0.080 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4

RP11-946L20.4

chr12_-_91576750 0.080 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
DCN


decorin


chr19_-_14064114 0.079 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
PODNL1



podocan-like 1



chr7_-_130080977 0.078 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr13_-_46626847 0.078 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13

chr9_+_44867571 0.078 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chrX_+_149887090 0.078 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr19_-_7697857 0.077 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr8_-_74495065 0.077 ENST00000523533.1
STAU2
staufen double-stranded RNA binding protein 2
chr15_+_45544426 0.077 ENST00000347644.3
ENST00000560438.1
SLC28A2

solute carrier family 28 (concentrative nucleoside transporter), member 2

chr11_-_94965667 0.076 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chr12_-_105630016 0.076 ENST00000258530.3
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr11_-_96076334 0.076 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr11_+_77532155 0.075 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC




adipogenesis associated, Mth938 domain containing




chr8_+_94752349 0.075 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr4_+_87857538 0.075 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr12_-_12715266 0.074 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr1_-_21377383 0.074 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_-_88974236 0.074 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr16_-_67517716 0.074 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chrX_-_122756660 0.074 ENST00000441692.1
THOC2
THO complex 2
chr10_+_115674530 0.074 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr12_-_46121554 0.073 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chrX_-_55208866 0.073 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr11_-_124190184 0.073 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr6_+_72922505 0.072 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr4_-_186733363 0.072 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr6_+_26087646 0.072 ENST00000309234.6
HFE
hemochromatosis
chr7_+_101460882 0.072 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr2_-_114461655 0.071 ENST00000424612.1
AC017074.2
AC017074.2
chr12_+_28410128 0.070 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chrX_-_138724994 0.069 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr20_+_45947246 0.069 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr1_+_117963209 0.069 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr9_-_34729457 0.068 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr15_-_37393406 0.068 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr5_-_112630598 0.068 ENST00000302475.4
MCC
mutated in colorectal cancers
chr1_+_205682497 0.067 ENST00000598338.1
AC119673.1
AC119673.1
chr1_-_48937838 0.067 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr2_-_44550441 0.067 ENST00000420756.1
ENST00000444696.1
PREPL

prolyl endopeptidase-like

chr17_-_62208169 0.067 ENST00000606895.1
ERN1
endoplasmic reticulum to nucleus signaling 1
chr18_-_21977748 0.067 ENST00000399441.4
ENST00000319481.3
OSBPL1A

oxysterol binding protein-like 1A

chr7_-_143599207 0.066 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
FAM115A


family with sequence similarity 115, member A


chr11_-_4719072 0.066 ENST00000396950.3
ENST00000532598.1
OR51E2

olfactory receptor, family 51, subfamily E, member 2

chr7_+_99613212 0.066 ENST00000426572.1
ENST00000535170.1
ZKSCAN1

zinc finger with KRAB and SCAN domains 1

chr1_-_117021430 0.066 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4


RP4-655J12.4


chr17_-_7145475 0.066 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr7_-_138386097 0.066 ENST00000421622.1
SVOPL
SVOP-like
chr14_-_78083112 0.065 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr3_+_155860751 0.065 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr3_-_157217328 0.065 ENST00000392832.2
ENST00000543418.1
VEPH1

ventricular zone expressed PH domain-containing 1

chr20_+_57414743 0.065 ENST00000313949.7
GNAS
GNAS complex locus
chr14_-_35099315 0.064 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6



sorting nexin 6



chr11_+_12766583 0.064 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_+_141106458 0.064 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_+_81601166 0.064 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr13_-_81801115 0.063 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr13_-_31191642 0.063 ENST00000405805.1
HMGB1
high mobility group box 1
chr10_+_13652047 0.063 ENST00000601460.1
RP11-295P9.3
Uncharacterized protein
chr13_+_103459704 0.063 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr2_+_170440844 0.062 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG



peptidylprolyl isomerase G (cyclophilin G)



chr8_-_116681221 0.062 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr4_-_19458597 0.062 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.2 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.1 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:2001190 peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.0 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0 0.0 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.0 GO:2000580 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) cell proliferation involved in outflow tract morphogenesis(GO:0061325) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:1901142 insulin metabolic process(GO:1901142)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.0 GO:0061580 colon epithelial cell migration(GO:0061580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.0 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.0 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle