Motif ID: MEIS1

Z-value: 0.845


Transcription factors associated with MEIS1:

Gene SymbolEntrez IDGene Name
MEIS1 ENSG00000143995.15 MEIS1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEIS1hg19_v2_chr2_+_66662510_66662532-0.255.2e-01Click!


Activity profile for motif MEIS1.

activity profile for motif MEIS1


Sorted Z-values histogram for motif MEIS1

Sorted Z-values for motif MEIS1



Network of associatons between targets according to the STRING database.



First level regulatory network of MEIS1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_87804815 2.122 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr22_-_36013368 1.640 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr2_-_68547061 1.214 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr1_-_109935819 1.205 ENST00000538502.1
SORT1
sortilin 1
chr12_-_71148413 1.074 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr16_-_46782221 0.837 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr12_-_71148357 0.740 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_147582387 0.623 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr1_-_12677714 0.600 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr10_-_69597915 0.545 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_178789993 0.515 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr2_+_33359687 0.513 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr10_+_114709999 0.500 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr10_-_69597828 0.498 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr19_-_42894420 0.487 ENST00000597255.1
ENST00000222032.5
CNFN

cornifelin

chr10_-_69597810 0.473 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr2_+_158114051 0.456 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr17_-_39661849 0.454 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13



keratin 13



chr10_+_54074033 0.454 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chrX_-_148713440 0.451 ENST00000536359.1
ENST00000316916.8
TMEM185A

transmembrane protein 185A

chr22_-_36018569 0.415 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr7_-_137028534 0.398 ENST00000348225.2
PTN
pleiotrophin
chr6_+_26124373 0.393 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr14_+_21492331 0.393 ENST00000533984.1
ENST00000532213.2
AL161668.5

AL161668.5

chr17_-_66287257 0.389 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr3_-_52486841 0.388 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr13_-_34250861 0.380 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3

RP11-141M1.3

chr4_-_130014532 0.378 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1


sodium channel and clathrin linker 1


chr12_-_71182695 0.371 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_33359646 0.363 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr19_-_49843539 0.362 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4

CTC-301O7.4

chr3_-_52488048 0.355 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr4_-_130014609 0.354 ENST00000511426.1
SCLT1
sodium channel and clathrin linker 1
chr1_-_16344500 0.352 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
HSPB7



heat shock 27kDa protein family, member 7 (cardiovascular)



chr4_-_130014705 0.351 ENST00000503401.1
SCLT1
sodium channel and clathrin linker 1
chr20_+_33759854 0.350 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr2_+_201936707 0.339 ENST00000433898.1
ENST00000454214.1
NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr2_-_68547019 0.338 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr4_-_130014729 0.325 ENST00000281142.5
ENST00000434680.1
SCLT1

sodium channel and clathrin linker 1

chr9_+_34652164 0.324 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr17_-_66287310 0.323 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr1_+_109102652 0.322 ENST00000370035.3
ENST00000405454.1
FAM102B

family with sequence similarity 102, member B

chr17_+_64298944 0.320 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr20_+_31749574 0.317 ENST00000253362.2
BPIFA2
BPI fold containing family A, member 2
chr5_+_147582348 0.316 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr1_-_241799232 0.316 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr17_-_41738931 0.315 ENST00000329168.3
ENST00000549132.1
MEOX1

mesenchyme homeobox 1

chr8_-_18744528 0.314 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr19_-_43702231 0.312 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr2_-_99279928 0.311 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_41739283 0.308 ENST00000393661.2
ENST00000318579.4
MEOX1

mesenchyme homeobox 1

chr2_-_145275828 0.307 ENST00000392861.2
ENST00000409211.1
ZEB2

zinc finger E-box binding homeobox 2

chr3_+_63897605 0.306 ENST00000487717.1
ATXN7
ataxin 7
chr10_-_123357598 0.305 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2



fibroblast growth factor receptor 2



chr15_+_59397275 0.305 ENST00000288207.2
CCNB2
cyclin B2
chr19_-_10764509 0.305 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chrX_-_148713365 0.302 ENST00000511776.1
ENST00000507237.1
TMEM185A

transmembrane protein 185A

chr15_+_101389945 0.300 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2


RP11-66B24.2


chr15_+_59397298 0.300 ENST00000559622.1
CCNB2
cyclin B2
chr7_+_94285637 0.297 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr2_-_24299308 0.291 ENST00000233468.4
SF3B14
Pre-mRNA branch site protein p14
chr9_+_127023704 0.289 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chr2_-_145275228 0.286 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2



zinc finger E-box binding homeobox 2



chr4_+_159593418 0.286 ENST00000507475.1
ENST00000307738.5
ETFDH

electron-transferring-flavoprotein dehydrogenase

chr8_+_125463048 0.286 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr7_-_137028498 0.285 ENST00000393083.2
PTN
pleiotrophin
chr19_-_10679697 0.281 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_-_26231589 0.280 ENST00000374291.1
STMN1
stathmin 1
chr17_-_66287350 0.279 ENST00000580666.1
ENST00000583477.1
SLC16A6

solute carrier family 16, member 6

chr2_-_8977714 0.278 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
KIDINS220





kinase D-interacting substrate, 220kDa





chr12_+_12938541 0.277 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr4_-_140477928 0.276 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr19_-_10679644 0.275 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr8_+_26240414 0.273 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr5_-_94417562 0.268 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr15_+_67458357 0.267 ENST00000537194.2
SMAD3
SMAD family member 3
chr4_-_174254823 0.265 ENST00000438704.2
HMGB2
high mobility group box 2
chr2_-_183106641 0.261 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_+_143381594 0.261 ENST00000367601.4
AIG1
androgen-induced 1
chrX_-_133931164 0.260 ENST00000370790.1
ENST00000298090.6
FAM122B

family with sequence similarity 122B

chr12_-_57634475 0.259 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr10_-_92681033 0.258 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_+_116263639 0.258 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr17_+_68165657 0.255 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chrX_+_102883887 0.255 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr4_+_41614909 0.254 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr11_-_33744256 0.250 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59


CD59 molecule, complement regulatory protein


chr5_-_112630598 0.249 ENST00000302475.4
MCC
mutated in colorectal cancers
chr3_-_58419537 0.246 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB



pyruvate dehydrogenase (lipoamide) beta



chr6_-_116833500 0.243 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr3_-_178789220 0.237 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr6_-_26124138 0.237 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr19_+_19174795 0.236 ENST00000318596.7
SLC25A42
solute carrier family 25, member 42
chr22_+_31518938 0.234 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr10_-_113943447 0.232 ENST00000369425.1
ENST00000348367.4
ENST00000423155.1
GPAM


glycerol-3-phosphate acyltransferase, mitochondrial


chr8_+_81397876 0.232 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr20_+_35201993 0.232 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr9_+_116263778 0.231 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr5_+_173763250 0.231 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1


RP11-267A15.1


chr1_-_115301235 0.228 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr5_+_122110691 0.228 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr2_-_36779411 0.226 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr9_-_131644306 0.225 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr5_+_43602750 0.224 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr12_-_46121554 0.224 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr9_-_123476612 0.221 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr3_-_49066811 0.219 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chr3_-_52001448 0.218 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chr12_+_7055631 0.217 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr1_+_210406121 0.216 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr16_+_2588012 0.216 ENST00000354836.5
ENST00000389224.3
PDPK1

3-phosphoinositide dependent protein kinase-1

chr14_+_37131058 0.216 ENST00000361487.6
PAX9
paired box 9
chrX_+_135251783 0.215 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr11_-_33744487 0.215 ENST00000426650.2
CD59
CD59 molecule, complement regulatory protein
chr3_-_24536222 0.215 ENST00000415021.1
ENST00000447875.1
THRB

thyroid hormone receptor, beta

chr2_-_25565377 0.215 ENST00000264709.3
ENST00000406659.3
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr5_+_43603229 0.214 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr1_+_110210644 0.214 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
GSTM2







glutathione S-transferase mu 2 (muscle)







chrX_+_73641286 0.213 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr3_+_140981456 0.213 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr10_+_18240834 0.212 ENST00000377371.3
ENST00000539911.1
SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr3_-_47205066 0.211 ENST00000412450.1
SETD2
SET domain containing 2
chr6_+_143381979 0.211 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1






androgen-induced 1






chr20_+_55204351 0.211 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr9_-_123476719 0.210 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr15_+_57884117 0.210 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr5_+_68463043 0.208 ENST00000508407.1
ENST00000505500.1
CCNB1

cyclin B1

chr22_-_39151995 0.207 ENST00000405018.1
ENST00000438058.1
SUN2

Sad1 and UNC84 domain containing 2

chr11_+_65265141 0.207 ENST00000534336.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr1_+_100111580 0.206 ENST00000605497.1
PALMD
palmdelphin
chr2_+_220436917 0.205 ENST00000243786.2
INHA
inhibin, alpha
chr19_+_36266417 0.205 ENST00000378944.5
ENST00000007510.4
ARHGAP33

Rho GTPase activating protein 33

chr4_+_14113592 0.205 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085



long intergenic non-protein coding RNA 1085



chr16_+_75600247 0.202 ENST00000037243.2
ENST00000565057.1
ENST00000563744.1
GABARAPL2


GABA(A) receptor-associated protein-like 2


chr6_+_106546808 0.201 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_151483855 0.201 ENST00000427934.2
ENST00000271636.7
CGN

cingulin

chr4_+_41614720 0.201 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr4_+_183065793 0.199 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr1_+_109419804 0.199 ENST00000435475.1
GPSM2
G-protein signaling modulator 2
chr15_-_58306295 0.197 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr6_-_75960024 0.196 ENST00000370081.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr1_+_94798754 0.196 ENST00000418242.1
RP11-148B18.3
RP11-148B18.3
chrX_-_130964596 0.194 ENST00000427391.1
RP11-453F18__B.1
RP11-453F18__B.1
chr10_-_91102410 0.194 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr4_+_110834033 0.194 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr8_-_124286735 0.193 ENST00000395571.3
ZHX1
zinc fingers and homeoboxes 1
chr4_-_23891693 0.193 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_-_41050716 0.193 ENST00000417193.1
ENST00000301683.3
ENST00000436546.1
ENST00000431109.2
LINC00671



long intergenic non-protein coding RNA 671



chr9_-_3469181 0.192 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr3_+_45730733 0.191 ENST00000418611.1
ENST00000389061.5
SACM1L

SAC1 suppressor of actin mutations 1-like (yeast)

chr15_-_90645679 0.190 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr6_+_72922590 0.190 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_178128528 0.190 ENST00000397063.4
ENST00000421929.1
NFE2L2

nuclear factor, erythroid 2-like 2

chr4_+_77870960 0.187 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11


septin 11


chr22_-_39190116 0.187 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
SUN2
DNAL4

Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4

chr22_-_39151947 0.186 ENST00000216064.4
SUN2
Sad1 and UNC84 domain containing 2
chr14_-_93799360 0.185 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7


BTB (POZ) domain containing 7


chr1_-_40782938 0.184 ENST00000372736.3
ENST00000372748.3
COL9A2

collagen, type IX, alpha 2

chr4_+_141445311 0.183 ENST00000323570.3
ENST00000511887.2
ELMOD2

ELMO/CED-12 domain containing 2

chr4_-_140477910 0.183 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr16_+_73420942 0.182 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1


RP11-140I24.1


chr3_-_160117301 0.182 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr3_+_183892635 0.180 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
AP2M1




adaptor-related protein complex 2, mu 1 subunit




chrX_+_150148976 0.180 ENST00000419110.1
HMGB3
high mobility group box 3
chr2_-_26467465 0.180 ENST00000457468.2
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr2_+_172778952 0.179 ENST00000392584.1
ENST00000264108.4
HAT1

histone acetyltransferase 1

chr10_+_114710211 0.177 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr17_-_73150629 0.177 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1


hematological and neurological expressed 1


chr17_-_44657017 0.177 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ARL17A





ADP-ribosylation factor-like 17A





chrX_+_70503037 0.177 ENST00000535149.1
NONO
non-POU domain containing, octamer-binding
chr8_+_81398444 0.175 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr12_-_118810688 0.175 ENST00000542532.1
ENST00000392533.3
TAOK3

TAO kinase 3

chr15_-_43882353 0.174 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
PPIP5K1







diphosphoinositol pentakisphosphate kinase 1







chr21_+_40823753 0.173 ENST00000333634.4
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr16_+_86229728 0.173 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr3_+_160117087 0.173 ENST00000357388.3
SMC4
structural maintenance of chromosomes 4
chr12_-_118498958 0.171 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr20_+_35201857 0.170 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr12_+_25205446 0.170 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr2_+_172864490 0.170 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr3_-_24536253 0.170 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr20_+_2795609 0.170 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr5_-_146435501 0.170 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr19_+_7694623 0.170 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100


PET100 homolog (S. cerevisiae)


chr5_-_154230130 0.169 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2



fatty acid hydroxylase domain containing 2



chr6_+_112408768 0.168 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr5_-_65018834 0.168 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_-_205053645 0.168 ENST00000367167.3
TMEM81
transmembrane protein 81
chr16_+_73266661 0.167 ENST00000561802.1
AC140912.1
AC140912.1
chr10_-_75255724 0.167 ENST00000342558.3
ENST00000360663.5
ENST00000394829.2
ENST00000394828.2
ENST00000394822.2
PPP3CB




protein phosphatase 3, catalytic subunit, beta isozyme




chr1_-_170043709 0.166 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3


kinesin-associated protein 3


chr9_+_133454943 0.166 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr3_+_160117418 0.166 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr9_+_116298778 0.166 ENST00000462143.1
RGS3
regulator of G-protein signaling 3
chr2_-_2334888 0.165 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr14_-_31676964 0.165 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr7_-_32111009 0.165 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr6_+_135502501 0.165 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chrX_-_13835461 0.165 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr10_-_16563870 0.164 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 2.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.7 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 1.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.8 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.2 0.5 GO:0100012 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.6 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.3 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.3 GO:0060648 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) mammary gland bud morphogenesis(GO:0060648) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.7 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.0 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 0.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.4 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.6 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 2.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:1902232 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.0 GO:0097695 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.3 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.2 GO:0009108 coenzyme biosynthetic process(GO:0009108)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0050932 regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0060926 atrioventricular node development(GO:0003162) His-Purkinje system development(GO:0003164) Purkinje myocyte development(GO:0003165) septum secundum development(GO:0003285) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1903979 regulation of microglial cell activation(GO:1903978) negative regulation of microglial cell activation(GO:1903979)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0097252 negative regulation of helicase activity(GO:0051097) oxidative stress-induced premature senescence(GO:0090403) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0030879 mammary gland development(GO:0030879)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0051685 endoplasmic reticulum localization(GO:0051643) maintenance of ER location(GO:0051685)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.0 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0008584 gonad development(GO:0008406) male gonad development(GO:0008584) development of primary sexual characteristics(GO:0045137) development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 0.0 GO:1901895 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:1903764 regulation of potassium ion export(GO:1902302) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 1.4 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.0 GO:0097451 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0044094 viral replication complex(GO:0019034) host cell nuclear part(GO:0044094)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.9 GO:0044815 DNA packaging complex(GO:0044815)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0009346 citrate lyase complex(GO:0009346)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 0.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.4 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 2.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 2.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.2 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 1.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 2.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 1.4 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.5 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events