Motif ID: MEF2D_MEF2A

Z-value: 0.523

Transcription factors associated with MEF2D_MEF2A:

Gene SymbolEntrez IDGene Name
MEF2A ENSG00000068305.13 MEF2A
MEF2D ENSG00000116604.13 MEF2D

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEF2Dhg19_v2_chr1_-_156470515_1564705420.333.9e-01Click!
MEF2Ahg19_v2_chr15_+_100106244_1001062920.314.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_53751445 0.897 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr4_+_37892682 0.875 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr3_-_52486841 0.835 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr14_-_21493123 0.767 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chr22_-_36013368 0.496 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr17_+_4855053 0.424 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr2_-_190044480 0.402 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_-_21493884 0.401 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr9_+_127054217 0.396 ENST00000394199.2
ENST00000546191.1
NEK6

NIMA-related kinase 6

chr15_+_59730348 0.365 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A



family with sequence similarity 81, member A



chr17_+_7184986 0.359 ENST00000317370.8
ENST00000571308.1
SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr6_+_26124373 0.351 ENST00000377791.2
ENST00000602637.1
HIST1H2AC

histone cluster 1, H2ac

chr4_+_41362796 0.345 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr1_-_12677714 0.325 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr9_+_127054254 0.302 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr22_-_36018569 0.278 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr2_-_148779106 0.277 ENST00000416719.1
ENST00000264169.2
ORC4

origin recognition complex, subunit 4

chr12_+_52431016 0.276 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr6_-_26124138 0.264 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chrX_-_128657457 0.261 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr4_-_23891693 0.255 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_31845914 0.238 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr8_+_40010989 0.236 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr5_+_173316341 0.234 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr3_-_48598547 0.228 ENST00000536104.1
ENST00000452531.1
PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr14_-_21493649 0.226 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr16_+_84328429 0.223 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr9_+_116327326 0.220 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr17_-_42200996 0.219 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5



histone deacetylase 5



chr18_-_3220106 0.219 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr16_+_84328252 0.218 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr2_-_148778323 0.216 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr15_-_83474806 0.215 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2


fibronectin type III and SPRY domain containing 2


chr3_-_176914238 0.207 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr9_+_100263912 0.197 ENST00000259365.4
TMOD1
tropomodulin 1
chr10_-_62704005 0.192 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr17_+_68165657 0.191 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr18_+_12407895 0.189 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1



slowmo homolog 1 (Drosophila)



chr3_+_54157480 0.187 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr8_-_17533838 0.179 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr17_-_42200958 0.176 ENST00000336057.5
HDAC5
histone deacetylase 5
chr9_-_23779367 0.173 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr5_-_16509101 0.172 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr5_-_137475071 0.165 ENST00000265191.2
NME5
NME/NM23 family member 5
chr3_+_138067314 0.163 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr18_-_3219847 0.162 ENST00000261606.7
MYOM1
myomesin 1
chr4_+_41362615 0.161 ENST00000509638.1
LIMCH1
LIM and calponin homology domains 1
chrX_-_21776281 0.160 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr6_-_116833500 0.160 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chrX_-_131353461 0.159 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chrX_-_117107680 0.158 ENST00000447671.2
ENST00000262820.3
KLHL13

kelch-like family member 13

chr2_-_208030886 0.156 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_+_49927006 0.154 ENST00000576655.1
CTD-3148I10.1
golgi-associated, olfactory signaling regulator
chr17_-_27949911 0.153 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6


coronin 6


chr2_-_208030647 0.152 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_+_89514516 0.151 ENST00000452979.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr12_+_40618764 0.146 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr2_-_148778258 0.143 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr7_+_18535346 0.143 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9


histone deacetylase 9


chr7_+_18535893 0.143 ENST00000432645.2
ENST00000441542.2
HDAC9

histone deacetylase 9

chr6_+_136172820 0.142 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr11_+_7598239 0.139 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_55095428 0.139 ENST00000508170.1
ENST00000512143.1
PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

chr14_-_103989033 0.134 ENST00000553878.1
ENST00000557530.1
CKB

creatine kinase, brain

chr17_-_48277552 0.134 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr6_+_27806319 0.134 ENST00000606613.1
ENST00000396980.3
HIST1H2BN

histone cluster 1, H2bn

chr11_+_7597639 0.134 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_26485511 0.132 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr3_+_138067666 0.131 ENST00000475711.1
ENST00000464896.1
MRAS

muscle RAS oncogene homolog

chr1_+_201979645 0.127 ENST00000367284.5
ENST00000367283.3
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr2_+_44502597 0.126 ENST00000260649.6
ENST00000409387.1
SLC3A1

solute carrier family 3 (amino acid transporter heavy chain), member 1

chr14_-_103589246 0.125 ENST00000558224.1
ENST00000560742.1
LINC00677

long intergenic non-protein coding RNA 677

chr12_+_12938541 0.124 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr8_-_62602327 0.120 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr2_+_11864458 0.119 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1


lipin 1


chr9_+_127023704 0.118 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chr17_+_27369918 0.116 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr1_-_223853425 0.116 ENST00000366873.2
ENST00000419193.2
CAPN8

calpain 8

chr6_+_26020672 0.114 ENST00000357647.3
HIST1H3A
histone cluster 1, H3a
chr1_-_153518270 0.112 ENST00000354332.4
ENST00000368716.4
S100A4

S100 calcium binding protein A4

chr14_-_62217779 0.112 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr1_-_223853348 0.110 ENST00000366872.5
CAPN8
calpain 8
chr14_+_56046990 0.104 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1


kinectin 1 (kinesin receptor)


chr7_+_143013198 0.101 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_-_104480019 0.101 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1


RP11-886D15.1


chr6_+_106535455 0.099 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr22_+_19706958 0.098 ENST00000395109.2
SEPT5
septin 5
chr7_-_151217001 0.098 ENST00000262187.5
RHEB
Ras homolog enriched in brain
chr17_-_1389228 0.096 ENST00000438665.2
MYO1C
myosin IC
chr2_+_33661382 0.096 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_182584314 0.095 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr16_+_12059091 0.095 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr8_+_76452097 0.095 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr4_+_89514402 0.094 ENST00000426683.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr10_+_88428370 0.094 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr10_-_13350447 0.093 ENST00000429930.1
AL138764.1
Uncharacterized protein
chr9_-_74980113 0.092 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5


zinc finger, AN1-type domain 5


chr8_-_66701319 0.091 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr10_-_45474237 0.091 ENST00000448778.1
ENST00000298295.3
C10orf10

chromosome 10 open reading frame 10

chr3_+_141106643 0.090 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_46121554 0.088 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr14_+_72052983 0.088 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chrX_-_133792480 0.088 ENST00000359237.4
PLAC1
placenta-specific 1
chr7_+_5465382 0.088 ENST00000609130.1
RP11-1275H24.2
RP11-1275H24.2
chr2_+_173686303 0.087 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_42984723 0.087 ENST00000332245.8
KLHDC3
kelch domain containing 3
chr14_+_56046914 0.086 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1



kinectin 1 (kinesin receptor)



chr1_-_117753540 0.086 ENST00000328189.3
ENST00000369458.3
VTCN1

V-set domain containing T cell activation inhibitor 1

chrX_+_591524 0.085 ENST00000554971.1
ENST00000381575.1
SHOX

short stature homeobox

chr5_-_95018660 0.085 ENST00000395899.3
ENST00000274432.8
SPATA9

spermatogenesis associated 9

chr12_+_44229846 0.085 ENST00000551577.1
ENST00000266534.3
TMEM117

transmembrane protein 117

chr11_-_47374246 0.083 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3


myosin binding protein C, cardiac


chr16_-_3422283 0.082 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr10_+_71561630 0.080 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1








collagen, type XIII, alpha 1








chr11_+_57308979 0.079 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr1_+_201979743 0.078 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_+_12058961 0.076 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr2_+_85804614 0.076 ENST00000263864.5
ENST00000409760.1
VAMP8

vesicle-associated membrane protein 8

chr3_-_156878540 0.076 ENST00000461804.1
CCNL1
cyclin L1
chr19_-_47164386 0.075 ENST00000391916.2
ENST00000410105.2
DACT3

dishevelled-binding antagonist of beta-catenin 3

chr2_-_106054952 0.075 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2


four and a half LIM domains 2


chr12_-_9268707 0.075 ENST00000318602.7
A2M
alpha-2-macroglobulin
chrX_-_55208866 0.075 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr15_+_42120283 0.075 ENST00000382448.4
ENST00000342159.4
ENST00000542534.2
ENST00000397299.4
ENST00000408047.1
ENST00000431823.1
JMJD7-PLA2G4B

PLA2G4B
JMJD7


JMJD7-PLA2G4B readthrough

phospholipase A2, group IVB (cytosolic)
jumonji domain containing 7


chr18_+_9708162 0.074 ENST00000578921.1
RAB31
RAB31, member RAS oncogene family
chr7_-_151217166 0.074 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr15_+_100106244 0.073 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr1_+_24018269 0.072 ENST00000374550.3
RPL11
ribosomal protein L11
chr6_+_26104104 0.071 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr17_-_41132088 0.071 ENST00000454303.1
ENST00000591916.1
ENST00000451885.2
PTGES3L-AARSD1
PTGES3L

PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 (cytosolic)-like

chr11_+_65266507 0.071 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr3_+_138067521 0.071 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr1_+_26348259 0.071 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr4_+_57276661 0.071 ENST00000598320.1
AC068620.1
Uncharacterized protein
chr9_+_5450503 0.071 ENST00000381573.4
ENST00000381577.3
CD274

CD274 molecule

chr12_+_6977258 0.070 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
TPI1


triosephosphate isomerase 1


chr3_-_27498235 0.070 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr1_+_190448095 0.069 ENST00000424735.1
RP11-547I7.2
RP11-547I7.2
chr17_+_6918064 0.069 ENST00000546760.1
ENST00000552402.1
C17orf49

chromosome 17 open reading frame 49

chr11_+_3666335 0.069 ENST00000250693.1
ART1
ADP-ribosyltransferase 1
chr2_-_208031542 0.069 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr15_+_74509530 0.068 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chr12_-_57644952 0.068 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr5_-_150521192 0.067 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chrX_+_119384607 0.067 ENST00000326624.2
ENST00000557385.1
ZBTB33

zinc finger and BTB domain containing 33

chr11_+_129245796 0.066 ENST00000281437.4
BARX2
BARX homeobox 2
chr3_+_141106458 0.065 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr6_-_27806117 0.065 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr1_+_150229554 0.064 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr17_+_37821593 0.064 ENST00000578283.1
TCAP
titin-cap
chr4_+_186064395 0.063 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr6_+_132129151 0.063 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr17_+_6918093 0.063 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr7_-_27702455 0.063 ENST00000265395.2
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr12_+_110562135 0.063 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
IFT81



intraflagellar transport 81 homolog (Chlamydomonas)



chr11_-_47400078 0.062 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_135424186 0.062 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr10_-_120840309 0.061 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr12_+_21207503 0.061 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr11_-_47399942 0.060 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_33160231 0.060 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr3_-_188665428 0.059 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr16_+_12059050 0.059 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr11_+_1942580 0.059 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr1_-_23751189 0.059 ENST00000374601.3
ENST00000450454.2
TCEA3

transcription elongation factor A (SII), 3

chr2_+_220144168 0.058 ENST00000392087.2
ENST00000442681.1
ENST00000439026.1
DNAJB2


DnaJ (Hsp40) homolog, subfamily B, member 2


chr14_-_21491477 0.057 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG2


NDRG family member 2


chr3_-_39234074 0.057 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1


xin actin-binding repeat containing 1


chr10_+_88428206 0.056 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr10_-_72141330 0.055 ENST00000395011.1
ENST00000395010.1
LRRC20

leucine rich repeat containing 20

chr9_+_21409146 0.055 ENST00000380205.1
IFNA8
interferon, alpha 8
chr11_-_62457371 0.055 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr6_+_159291090 0.054 ENST00000367073.4
ENST00000608817.1
C6orf99

chromosome 6 open reading frame 99

chr4_-_185303418 0.054 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1

RP11-290F5.1

chr6_+_159290917 0.054 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr5_+_138609782 0.054 ENST00000361059.2
ENST00000514694.1
ENST00000504203.1
ENST00000502929.1
ENST00000394800.2
ENST00000509644.1
ENST00000505016.1
MATR3






matrin 3






chr16_-_85969774 0.054 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr9_-_33402506 0.053 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr11_-_47400062 0.053 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr14_-_81916501 0.053 ENST00000555001.1
RP11-299L17.3
RP11-299L17.3
chr9_+_21440440 0.053 ENST00000276927.1
IFNA1
interferon, alpha 1
chr17_+_7788104 0.053 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr4_-_39640513 0.052 ENST00000511809.1
ENST00000505729.1
SMIM14

small integral membrane protein 14

chr11_+_75110530 0.052 ENST00000531188.1
ENST00000530164.1
ENST00000422465.2
ENST00000278572.6
ENST00000534440.1
ENST00000527446.1
ENST00000526608.1
ENST00000527273.1
ENST00000524851.1
RPS3








ribosomal protein S3








chr4_-_23891658 0.052 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chrX_+_123095860 0.052 ENST00000428941.1
STAG2
stromal antigen 2
chr2_+_85766280 0.050 ENST00000306434.3
MAT2A
methionine adenosyltransferase II, alpha
chr11_+_12766583 0.050 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chrM_+_7586 0.050 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr22_+_25595817 0.050 ENST00000215855.2
ENST00000404334.1
CRYBB3

crystallin, beta B3

chr19_-_49926698 0.050 ENST00000270631.1
PTH2
parathyroid hormone 2
chr3_+_186739636 0.050 ENST00000440338.1
ENST00000448044.1
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr8_+_74903580 0.049 ENST00000284818.2
ENST00000518893.1
LY96

lymphocyte antigen 96

chr17_-_1389419 0.049 ENST00000575158.1
MYO1C
myosin IC
chr9_-_134151915 0.049 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr19_+_14672755 0.049 ENST00000594545.1
TECR
trans-2,3-enoyl-CoA reductase
chr15_-_52944231 0.049 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr14_+_56078695 0.049 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr4_-_170192000 0.048 ENST00000502315.1
SH3RF1
SH3 domain containing ring finger 1
chr10_-_6104253 0.047 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA


interleukin 2 receptor, alpha



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.8 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.0 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction