Motif ID: MBD2

Z-value: 0.409


Transcription factors associated with MBD2:

Gene SymbolEntrez IDGene Name
MBD2 ENSG00000134046.7 MBD2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51750948_517510590.402.9e-01Click!


Activity profile for motif MBD2.

activity profile for motif MBD2


Sorted Z-values histogram for motif MBD2

Sorted Z-values for motif MBD2



Network of associatons between targets according to the STRING database.



First level regulatory network of MBD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_40499661 0.374 ENST00000280871.4
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr1_-_150552006 0.306 ENST00000307940.3
ENST00000369026.2
MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

chr22_+_41487711 0.295 ENST00000263253.7
EP300
E1A binding protein p300
chr11_+_43380459 0.286 ENST00000299240.6
ENST00000039989.4
TTC17

tetratricopeptide repeat domain 17

chr6_+_41514305 0.269 ENST00000409208.1
ENST00000373057.3
FOXP4

forkhead box P4

chr13_-_80915059 0.267 ENST00000377104.3
SPRY2
sprouty homolog 2 (Drosophila)
chr5_+_153570319 0.265 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr20_-_48330377 0.255 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr5_+_153570285 0.235 ENST00000425427.2
ENST00000297107.6
GALNT10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

chr12_-_49453557 0.224 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr20_-_30310797 0.222 ENST00000422920.1
BCL2L1
BCL2-like 1
chr6_+_29795595 0.204 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
HLA-G


major histocompatibility complex, class I, G


chr12_-_48213568 0.186 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7




histone deacetylase 7




chr5_+_14143728 0.185 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr11_-_67141090 0.179 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr12_+_68042517 0.176 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr19_+_56152361 0.176 ENST00000585995.1
ENST00000592996.1
ZNF581
CCDC106
zinc finger protein 581
coiled-coil domain containing 106
chr20_-_30311703 0.173 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1



BCL2-like 1



chr20_-_39317868 0.170 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr11_-_78128811 0.168 ENST00000530915.1
ENST00000361507.4
GAB2

GRB2-associated binding protein 2

chr15_+_92397051 0.168 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr11_-_72353494 0.167 ENST00000544570.1
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_-_72353451 0.163 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr17_-_79876010 0.161 ENST00000328666.6
SIRT7
sirtuin 7
chr4_+_38665810 0.159 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chrX_+_18443703 0.159 ENST00000379996.3
CDKL5
cyclin-dependent kinase-like 5
chr3_-_128206759 0.157 ENST00000430265.2
GATA2
GATA binding protein 2
chr12_+_122064673 0.157 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr11_+_74459876 0.157 ENST00000299563.4
RNF169
ring finger protein 169
chr12_-_57400227 0.156 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr3_-_52090461 0.154 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr16_+_2022036 0.154 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr2_+_9346892 0.151 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr17_+_65821636 0.149 ENST00000544778.2
BPTF
bromodomain PHD finger transcription factor
chr22_-_46373004 0.148 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr1_-_115053781 0.144 ENST00000358465.2
ENST00000369543.2
TRIM33

tripartite motif containing 33

chr4_+_79697495 0.143 ENST00000502871.1
ENST00000335016.5
BMP2K

BMP2 inducible kinase

chr3_+_159481988 0.142 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr2_-_128615517 0.141 ENST00000409698.1
POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr9_+_34989638 0.140 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr2_+_173292390 0.140 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr5_+_179159813 0.140 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr8_+_61592073 0.140 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr2_-_219537134 0.138 ENST00000295704.2
RNF25
ring finger protein 25
chr16_+_1823208 0.136 ENST00000568449.1
ENST00000307394.7
EME2

essential meiotic structure-specific endonuclease subunit 2

chr20_-_48532046 0.136 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr20_+_34894247 0.136 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr17_+_48133459 0.132 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_+_39904168 0.132 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
PLEKHG2


pleckstrin homology domain containing, family G (with RhoGef domain) member 2


chr3_-_194207388 0.129 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr17_-_41623075 0.127 ENST00000545089.1
ETV4
ets variant 4
chr1_-_149982624 0.125 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr4_-_78740769 0.125 ENST00000512485.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr1_+_9648921 0.124 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
TMEM201


transmembrane protein 201


chr17_-_41623259 0.122 ENST00000538265.1
ENST00000591713.1
ETV4

ets variant 4

chr17_+_46125685 0.122 ENST00000579889.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr19_+_42388437 0.122 ENST00000378152.4
ENST00000337665.4
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr12_-_29936731 0.121 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
TMTC1


transmembrane and tetratricopeptide repeat containing 1


chr5_-_180236811 0.121 ENST00000446023.2
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr17_+_46126135 0.119 ENST00000361665.3
ENST00000585062.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr1_+_145611010 0.118 ENST00000369291.5
RNF115
ring finger protein 115
chr20_-_48532019 0.118 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr19_-_42759300 0.118 ENST00000222329.4
ERF
Ets2 repressor factor
chr8_-_67525524 0.116 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr17_+_46125707 0.113 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr1_+_156698743 0.112 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr16_-_23160591 0.111 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr12_-_48213735 0.111 ENST00000417902.1
ENST00000417107.1
HDAC7

histone deacetylase 7

chr22_+_25348671 0.110 ENST00000406486.4
KIAA1671
KIAA1671
chr17_-_27278445 0.110 ENST00000268756.3
ENST00000584685.1
PHF12

PHD finger protein 12

chr3_-_124774802 0.110 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr11_+_118978045 0.109 ENST00000336702.3
C2CD2L
C2CD2-like
chr20_-_50808290 0.108 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
ZFP64


ZFP64 zinc finger protein


chr2_+_48541776 0.108 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr16_+_3019309 0.107 ENST00000576565.1
PAQR4
progestin and adipoQ receptor family member IV
chr12_+_3068957 0.106 ENST00000543035.1
TEAD4
TEA domain family member 4
chr5_+_167718604 0.106 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr17_-_41623009 0.105 ENST00000393664.2
ETV4
ets variant 4
chr2_-_220408430 0.103 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr2_+_208576259 0.103 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chr11_+_100558384 0.103 ENST00000524892.2
ENST00000298815.8
ARHGAP42

Rho GTPase activating protein 42

chrX_-_53350522 0.101 ENST00000396435.3
ENST00000375368.5
IQSEC2

IQ motif and Sec7 domain 2

chr19_-_41196534 0.100 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr11_+_66025938 0.099 ENST00000394066.2
KLC2
kinesin light chain 2
chr4_-_153456153 0.099 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_247495045 0.099 ENST00000294753.4
ENST00000366498.2
ZNF496

zinc finger protein 496

chr19_-_41196458 0.098 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr15_+_40763150 0.097 ENST00000306243.5
ENST00000559991.1
CHST14

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

chr15_-_73925651 0.097 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN


neuroplastin


chr10_+_98592674 0.096 ENST00000356016.3
ENST00000371097.4
LCOR

ligand dependent nuclear receptor corepressor

chr18_-_72265035 0.096 ENST00000585279.1
ENST00000580048.1
LINC00909

long intergenic non-protein coding RNA 909

chr1_-_156698591 0.096 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr2_+_220299547 0.096 ENST00000312358.7
SPEG
SPEG complex locus
chr11_+_35965531 0.096 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3


low density lipoprotein receptor class A domain containing 3


chr2_+_149402553 0.095 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr1_-_156698181 0.095 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr5_+_10564432 0.092 ENST00000296657.5
ANKRD33B
ankyrin repeat domain 33B
chr9_+_35605274 0.091 ENST00000336395.5
TESK1
testis-specific kinase 1
chr19_+_4007644 0.090 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr20_-_60640866 0.090 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr20_+_60878005 0.090 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr2_-_129076151 0.090 ENST00000259241.6
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr16_-_2059748 0.089 ENST00000562103.1
ENST00000431526.1
ZNF598

zinc finger protein 598

chr2_+_173292301 0.089 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chr19_-_663171 0.089 ENST00000606896.1
ENST00000589762.2
RNF126

ring finger protein 126

chr15_-_73925575 0.089 ENST00000562924.1
ENST00000563691.1
ENST00000565325.1
ENST00000542234.1
NPTN



neuroplastin



chr2_-_9695847 0.089 ENST00000310823.3
ENST00000497134.1
ADAM17

ADAM metallopeptidase domain 17

chr6_+_160148593 0.089 ENST00000337387.4
WTAP
Wilms tumor 1 associated protein
chr12_+_7037461 0.088 ENST00000396684.2
ATN1
atrophin 1
chr12_+_50479109 0.088 ENST00000550477.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_208576355 0.088 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1


cyclin Y-like 1


chr1_+_167190066 0.087 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr8_-_119124045 0.087 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr6_+_84569359 0.086 ENST00000369681.5
ENST00000369679.4
CYB5R4

cytochrome b5 reductase 4

chr19_+_6739662 0.086 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10


thyroid hormone receptor interactor 10


chr21_+_34915337 0.086 ENST00000290239.6
ENST00000381692.2
ENST00000300278.4
ENST00000381679.4
SON



SON DNA binding protein



chr11_-_64545941 0.086 ENST00000377387.1
SF1
splicing factor 1
chr12_-_117318788 0.085 ENST00000550505.1
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr2_+_219537015 0.084 ENST00000440309.1
ENST00000424080.1
STK36

serine/threonine kinase 36

chr19_-_19051103 0.084 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr9_+_124413873 0.084 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr12_+_50478977 0.083 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr6_+_41514078 0.082 ENST00000373063.3
ENST00000373060.1
FOXP4

forkhead box P4

chr5_-_56247935 0.082 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3


mesoderm induction early response 1, family member 3


chr1_-_47184745 0.081 ENST00000544071.1
EFCAB14
EF-hand calcium binding domain 14
chr20_-_50808236 0.081 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr19_+_36208877 0.080 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B


Histone-lysine N-methyltransferase 2B


chr3_-_39195037 0.080 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr1_-_43855444 0.079 ENST00000372455.4
MED8
mediator complex subunit 8
chr14_-_74416829 0.079 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr1_+_110881945 0.079 ENST00000602849.1
ENST00000487146.2
RBM15

RNA binding motif protein 15

chr16_+_3019246 0.079 ENST00000318782.8
ENST00000293978.8
PAQR4

progestin and adipoQ receptor family member IV

chr20_+_43104541 0.079 ENST00000372906.2
ENST00000456317.1
TTPAL

tocopherol (alpha) transfer protein-like

chr11_-_65429891 0.078 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr14_-_62162541 0.078 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr17_+_43299241 0.078 ENST00000328118.3
FMNL1
formin-like 1
chr11_+_45168182 0.078 ENST00000526442.1
PRDM11
PR domain containing 11
chr6_+_1389989 0.078 ENST00000259806.1
FOXF2
forkhead box F2
chr5_-_127873659 0.078 ENST00000262464.4
FBN2
fibrillin 2
chr17_+_43299156 0.078 ENST00000331495.3
FMNL1
formin-like 1
chr3_+_133292851 0.077 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr20_-_1447467 0.077 ENST00000353088.2
ENST00000350991.4
NSFL1C

NSFL1 (p97) cofactor (p47)

chr9_+_35732312 0.076 ENST00000353704.2
CREB3
cAMP responsive element binding protein 3
chr16_+_67226019 0.076 ENST00000379378.3
E2F4
E2F transcription factor 4, p107/p130-binding
chr9_+_103189405 0.076 ENST00000395067.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr15_+_40650408 0.076 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr6_+_37321748 0.075 ENST00000373479.4
ENST00000394443.4
RNF8

ring finger protein 8, E3 ubiquitin protein ligase

chr13_-_21476900 0.075 ENST00000400602.2
ENST00000255305.6
XPO4

exportin 4

chr12_+_46123682 0.075 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr16_-_89787360 0.075 ENST00000389386.3
VPS9D1
VPS9 domain containing 1
chr22_-_39096925 0.074 ENST00000456626.1
ENST00000412832.1
JOSD1

Josephin domain containing 1

chr11_+_66886717 0.073 ENST00000398645.2
KDM2A
lysine (K)-specific demethylase 2A
chr2_-_70529126 0.073 ENST00000438759.1
ENST00000430566.1
FAM136A

family with sequence similarity 136, member A

chr22_-_19419205 0.073 ENST00000340170.4
ENST00000263208.5
HIRA

histone cell cycle regulator

chr22_-_42739533 0.073 ENST00000515426.1
TCF20
transcription factor 20 (AR1)
chr16_+_3019552 0.073 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr3_-_32612263 0.073 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
DYNC1LI1


dynein, cytoplasmic 1, light intermediate chain 1


chr19_-_663147 0.072 ENST00000606702.1
RNF126
ring finger protein 126
chr3_-_53080047 0.072 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr16_+_3451184 0.072 ENST00000575752.1
ENST00000571936.1
ENST00000344823.5
ZNF174


zinc finger protein 174


chr20_-_1447547 0.072 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr20_-_50808525 0.072 ENST00000216923.4
ZFP64
ZFP64 zinc finger protein
chr5_-_107717058 0.072 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr11_-_64545222 0.071 ENST00000433274.2
ENST00000432725.1
SF1

splicing factor 1

chr16_-_3450963 0.071 ENST00000573327.1
ENST00000571906.1
ENST00000573830.1
ENST00000439568.2
ENST00000422427.2
ENST00000304926.3
ENST00000396852.4
ZSCAN32






zinc finger and SCAN domain containing 32






chr1_+_156252708 0.071 ENST00000295694.5
ENST00000357501.2
TMEM79

transmembrane protein 79

chr9_-_140115775 0.070 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr3_+_47422485 0.070 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23


protein tyrosine phosphatase, non-receptor type 23


chr1_+_116184566 0.070 ENST00000355485.2
ENST00000369510.4
VANGL1

VANGL planar cell polarity protein 1

chr1_+_179851893 0.069 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr19_-_1568057 0.069 ENST00000402693.4
ENST00000388824.6
MEX3D

mex-3 RNA binding family member D

chr20_+_43104508 0.069 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr2_+_219536749 0.068 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36



serine/threonine kinase 36



chr11_-_47198380 0.068 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2








ADP-ribosylation factor GTPase activating protein 2








chr19_+_38397839 0.067 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr3_+_14989186 0.067 ENST00000435454.1
ENST00000323373.6
NR2C2

nuclear receptor subfamily 2, group C, member 2

chr1_-_47184723 0.066 ENST00000371933.3
EFCAB14
EF-hand calcium binding domain 14
chr1_-_43855479 0.066 ENST00000290663.6
ENST00000372457.4
MED8

mediator complex subunit 8

chr12_+_50479101 0.065 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_+_114472481 0.064 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr3_+_120461484 0.064 ENST00000484715.1
ENST00000469772.1
ENST00000283875.5
ENST00000492959.1
GTF2E1



general transcription factor IIE, polypeptide 1, alpha 56kDa



chr9_+_103189458 0.063 ENST00000398977.2
MSANTD3
Myb/SANT-like DNA-binding domain containing 3
chr19_-_36545649 0.062 ENST00000292894.1
THAP8
THAP domain containing 8
chr5_+_149865838 0.061 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_-_2059797 0.061 ENST00000563630.1
ZNF598
zinc finger protein 598
chr1_+_43855545 0.061 ENST00000372450.4
ENST00000310739.4
SZT2

seizure threshold 2 homolog (mouse)

chrX_-_40594755 0.061 ENST00000324817.1
MED14
mediator complex subunit 14
chr3_-_185542761 0.060 ENST00000457616.2
ENST00000346192.3
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr19_+_36545833 0.060 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62


WD repeat domain 62


chr3_-_176915036 0.060 ENST00000427349.1
ENST00000352800.5
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr12_-_58159361 0.059 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr14_-_100070363 0.059 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr20_-_62710832 0.058 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr5_+_132387633 0.058 ENST00000304858.2
HSPA4
heat shock 70kDa protein 4
chr22_-_38239808 0.058 ENST00000406423.1
ENST00000424350.1
ENST00000458278.2
ANKRD54


ankyrin repeat domain 54


chr1_+_179851999 0.057 ENST00000527391.1
TOR1AIP1
torsin A interacting protein 1
chr7_-_558876 0.057 ENST00000354513.5
ENST00000402802.3
PDGFA

platelet-derived growth factor alpha polypeptide

chr2_+_47630255 0.057 ENST00000406134.1
MSH2
mutS homolog 2
chr11_+_67056755 0.056 ENST00000511455.2
ENST00000308440.6
ANKRD13D

ankyrin repeat domain 13 family, member D

chr3_+_133292759 0.056 ENST00000431519.2
CDV3
CDV3 homolog (mouse)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.2 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0055099 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.0 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0060235 embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.0 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes