Motif ID: MAX_TFEB

Z-value: 0.459

Transcription factors associated with MAX_TFEB:

Gene SymbolEntrez IDGene Name
MAX ENSG00000125952.14 MAX
TFEB ENSG00000112561.13 TFEB

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAXhg19_v2_chr14_-_65569186_65569243-0.917.2e-04Click!
TFEBhg19_v2_chr6_-_41701581_417016130.245.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MAX_TFEB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_93392811 0.765 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr17_+_48503519 0.681 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2




acyl-CoA synthetase family member 2




chr15_+_44084040 0.678 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr12_+_123849462 0.655 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr17_-_7137857 0.617 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr3_-_4508925 0.608 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1




sulfatase modifying factor 1




chr17_+_48503603 0.607 ENST00000502667.1
ACSF2
acyl-CoA synthetase family member 2
chr17_-_7137582 0.596 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr5_-_121413974 0.580 ENST00000231004.4
LOX
lysyl oxidase
chr2_+_176981307 0.549 ENST00000249501.4
HOXD10
homeobox D10
chr16_+_2570340 0.527 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr17_+_57408994 0.499 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr10_-_76995769 0.491 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr4_+_111397216 0.486 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr10_-_76995675 0.481 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr11_-_61560053 0.477 ENST00000537328.1
TMEM258
transmembrane protein 258
chr6_+_123110465 0.462 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr6_+_151773583 0.449 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr8_+_142402089 0.445 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr6_+_123110302 0.438 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr15_+_44084503 0.437 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr19_+_2977444 0.437 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6



transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)



chr11_-_57283159 0.424 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr16_+_19467772 0.423 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5


transmembrane channel-like 5


chr4_+_172734548 0.416 ENST00000506823.1
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr18_-_3247084 0.409 ENST00000609924.1
RP13-270P17.3
RP13-270P17.3
chr12_+_56109926 0.407 ENST00000547076.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_+_56109810 0.406 ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
ENST00000550412.1
BLOC1S1


RP11-644F5.10
biogenesis of lysosomal organelles complex-1, subunit 1


Uncharacterized protein
chr12_+_53400176 0.403 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B




eukaryotic translation initiation factor 4B




chr2_+_30370382 0.401 ENST00000402708.1
YPEL5
yippee-like 5 (Drosophila)
chrX_-_13835461 0.400 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chrX_-_13835147 0.395 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr1_-_154193091 0.394 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43


chromosome 1 open reading frame 43


chr2_+_176972000 0.392 ENST00000249504.5
HOXD11
homeobox D11
chr20_-_2821271 0.386 ENST00000448755.1
ENST00000360652.2
PCED1A

PC-esterase domain containing 1A

chr11_+_67776012 0.386 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr11_-_66725837 0.377 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr11_-_61560254 0.377 ENST00000543510.1
TMEM258
transmembrane protein 258
chr12_+_56110247 0.366 ENST00000551926.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_-_154193009 0.361 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chr12_+_53399942 0.352 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chr6_-_43197189 0.348 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr11_-_62446527 0.343 ENST00000294119.2
ENST00000529640.1
ENST00000534176.1
ENST00000301935.5
UBXN1



UBX domain protein 1



chr20_+_44519948 0.342 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr20_+_44520009 0.339 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr3_-_112280709 0.339 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
ATG3


autophagy related 3


chr16_-_30134441 0.335 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr19_-_45681482 0.332 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A



trafficking protein particle complex 6A



chr5_+_43603229 0.326 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chr19_-_10047219 0.325 ENST00000264833.4
OLFM2
olfactomedin 2
chr6_+_87865262 0.321 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr8_+_103876528 0.321 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2

HCG15011, isoform CRA_a; Protein LOC100996457

chr7_+_155090271 0.320 ENST00000476756.1
INSIG1
insulin induced gene 1
chr1_-_31845914 0.318 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr19_+_5681011 0.314 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr11_+_7534999 0.308 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chrX_+_30671476 0.307 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr19_-_15236173 0.304 ENST00000527093.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr3_-_178789220 0.294 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr2_+_85981008 0.294 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr15_-_72668805 0.289 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr19_-_33793430 0.288 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_-_49137762 0.285 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr8_-_75233563 0.284 ENST00000342232.4
JPH1
junctophilin 1
chr10_-_105437909 0.282 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr15_-_72668185 0.280 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr19_-_49137790 0.277 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chrX_+_102631844 0.269 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr19_+_49990811 0.268 ENST00000391857.4
ENST00000467825.2
RPL13A

ribosomal protein L13a

chrX_+_102631248 0.267 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr11_-_66336060 0.265 ENST00000310325.5
CTSF
cathepsin F
chrX_+_100663243 0.262 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr16_-_88923285 0.258 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr1_-_11866034 0.258 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_-_2821756 0.257 ENST00000356872.3
ENST00000439542.1
PCED1A

PC-esterase domain containing 1A

chr17_+_46970178 0.254 ENST00000393366.2
ENST00000506855.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr17_-_6915616 0.253 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr20_+_57766075 0.252 ENST00000371030.2
ZNF831
zinc finger protein 831
chr16_+_2570431 0.251 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr19_-_8386238 0.251 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr13_+_113951532 0.249 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr3_-_122512619 0.247 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr15_+_75118888 0.246 ENST00000395018.4
CPLX3
complexin 3
chr17_+_46970127 0.245 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_+_56110315 0.244 ENST00000548556.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_44225231 0.243 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
SLC35B2



solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2



chr11_+_61560348 0.241 ENST00000574708.1
ENST00000535723.1
FADS2
FEN1
fatty acid desaturase 2
flap structure-specific endonuclease 1
chr11_-_36310958 0.241 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9


COMM domain containing 9


chr5_+_122110691 0.239 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr22_-_38577782 0.233 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6





phospholipase A2, group VI (cytosolic, calcium-independent)





chr9_+_133320301 0.233 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr12_-_110011288 0.230 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr17_+_46970134 0.227 ENST00000503641.1
ENST00000514808.1
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr19_-_11545920 0.227 ENST00000356392.4
ENST00000591179.1
CCDC151

coiled-coil domain containing 151

chr1_-_26233423 0.223 ENST00000357865.2
STMN1
stathmin 1
chr4_-_100871506 0.223 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr15_-_77197620 0.216 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr5_-_176730676 0.216 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24


RAB24, member RAS oncogene family


chr22_+_39916558 0.215 ENST00000337304.2
ENST00000396680.1
ATF4

activating transcription factor 4

chr14_-_64970494 0.215 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr17_-_76124812 0.211 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
TMC6



transmembrane channel-like 6



chr14_-_74551096 0.210 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr3_+_113465866 0.209 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr19_-_15236562 0.208 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr19_-_5720123 0.207 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
LONP1


lon peptidase 1, mitochondrial


chr1_-_154928562 0.204 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1




pre-B-cell leukemia homeobox interacting protein 1




chr17_-_49337392 0.204 ENST00000376381.2
ENST00000586178.1
MBTD1

mbt domain containing 1

chr17_-_76124711 0.204 ENST00000306591.7
ENST00000590602.1
TMC6

transmembrane channel-like 6

chr8_-_95961578 0.203 ENST00000448464.2
ENST00000342697.4
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr1_-_28559502 0.203 ENST00000263697.4
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr7_+_99746514 0.202 ENST00000341942.5
ENST00000441173.1
LAMTOR4

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

chr19_-_5720248 0.202 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr9_-_123476719 0.200 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr20_+_57427765 0.200 ENST00000371100.4
GNAS
GNAS complex locus
chr19_+_41903709 0.200 ENST00000542943.1
ENST00000457836.2
BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr19_-_15236470 0.199 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL


ilvB (bacterial acetolactate synthase)-like


chr17_+_42977062 0.196 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103


coiled-coil domain containing 103


chr14_-_74551172 0.196 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr19_+_8386371 0.192 ENST00000600659.2
RPS28
ribosomal protein S28
chr13_+_113951607 0.191 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr3_+_52017454 0.190 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1




aminoacylase 1




chr21_+_38445539 0.189 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chr19_-_5680891 0.188 ENST00000309324.4
C19orf70
chromosome 19 open reading frame 70
chr17_-_18266797 0.184 ENST00000316694.3
ENST00000539052.1
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr9_-_123476612 0.183 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr22_-_42765174 0.182 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1


Z83851.1


chr6_-_33385902 0.180 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_+_33116743 0.180 ENST00000414241.3
ENST00000373493.5
RBBP4

retinoblastoma binding protein 4

chr18_+_21594384 0.179 ENST00000584250.1
TTC39C
tetratricopeptide repeat domain 39C
chr16_-_30134524 0.179 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr17_-_18266660 0.179 ENST00000582653.1
ENST00000352886.6
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr3_+_158519654 0.178 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr5_+_34656331 0.174 ENST00000265109.3
RAI14
retinoic acid induced 14
chr19_-_5719860 0.174 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr12_-_56710118 0.173 ENST00000273308.4
CNPY2
canopy FGF signaling regulator 2
chr1_+_202995611 0.173 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr12_+_6644443 0.172 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr17_-_18266765 0.172 ENST00000354098.3
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr10_-_73611046 0.171 ENST00000394934.1
ENST00000394936.3
PSAP

prosaposin

chr17_+_48450575 0.171 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1


essential meiotic structure-specific endonuclease 1


chr11_+_118938485 0.170 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_+_33116765 0.169 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
RBBP4




retinoblastoma binding protein 4




chr14_-_75643296 0.166 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr3_+_99536663 0.166 ENST00000421999.2
ENST00000463526.1
CMSS1

cms1 ribosomal small subunit homolog (yeast)

chrX_-_15872914 0.165 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2



adaptor-related protein complex 1, sigma 2 subunit



chr3_+_112280857 0.164 ENST00000492406.1
ENST00000468642.1
SLC35A5

solute carrier family 35, member A5

chr8_+_26240414 0.163 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr17_+_74723031 0.161 ENST00000586200.1
METTL23
methyltransferase like 23
chr18_+_9913977 0.158 ENST00000400000.2
ENST00000340541.4
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr18_-_48346415 0.158 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr16_-_5083917 0.155 ENST00000312251.3
ENST00000381955.3
NAGPA

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chr3_-_45883558 0.154 ENST00000445698.1
ENST00000296135.6
LZTFL1

leucine zipper transcription factor-like 1

chr19_+_40854559 0.153 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3








phospholipase D family, member 3








chr10_+_99344071 0.153 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr6_-_33385870 0.153 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr7_+_116593536 0.152 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr12_-_56709674 0.152 ENST00000549318.1
ENST00000551286.1
RP11-977G19.10
CNPY2
Uncharacterized protein
canopy FGF signaling regulator 2
chr5_+_133706865 0.151 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr1_+_10092890 0.151 ENST00000253251.8
ENST00000377157.3
UBE4B

ubiquitination factor E4B

chr3_+_140660634 0.151 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36


solute carrier family 25 (pyrimidine nucleotide carrier ), member 36


chr14_-_35183755 0.150 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr9_-_134145880 0.150 ENST00000372269.3
ENST00000464831.1
FAM78A

family with sequence similarity 78, member A

chr17_+_79935464 0.150 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr16_+_1401924 0.148 ENST00000204679.4
ENST00000529110.1
GNPTG

N-acetylglucosamine-1-phosphate transferase, gamma subunit

chr16_-_70323422 0.147 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr19_-_12886327 0.146 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2


hook microtubule-tethering protein 2


chr10_+_69644404 0.145 ENST00000212015.6
SIRT1
sirtuin 1
chr2_-_220083692 0.145 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr5_-_175964366 0.145 ENST00000274811.4
RNF44
ring finger protein 44
chr17_-_42200996 0.144 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5



histone deacetylase 5



chr2_-_220083671 0.142 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr5_+_34656569 0.140 ENST00000428746.2
RAI14
retinoic acid induced 14
chr16_-_81129845 0.140 ENST00000569885.1
ENST00000566566.1
GCSH

glycine cleavage system protein H (aminomethyl carrier)

chr7_-_42951509 0.140 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
C7orf25





chromosome 7 open reading frame 25





chr4_+_128651530 0.140 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr6_-_33385655 0.140 ENST00000440279.3
ENST00000607266.1
CUTA

cutA divalent cation tolerance homolog (E. coli)

chr17_+_79935418 0.139 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr17_+_40688190 0.139 ENST00000225927.2
NAGLU
N-acetylglucosaminidase, alpha
chr3_-_17783990 0.139 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr15_-_77197781 0.139 ENST00000564590.1
SCAPER
S-phase cyclin A-associated protein in the ER
chr2_-_200715834 0.138 ENST00000420128.1
ENST00000416668.1
FTCDNL1

formiminotransferase cyclodeaminase N-terminal like

chr9_-_139948468 0.138 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr14_-_21852119 0.137 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr11_-_1785139 0.137 ENST00000236671.2
CTSD
cathepsin D
chr22_-_38577731 0.137 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr9_-_140009130 0.136 ENST00000497375.1
ENST00000371579.2
DPP7

dipeptidyl-peptidase 7

chr12_-_56709786 0.136 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
RP11-977G19.10

CNPY2
Uncharacterized protein

canopy FGF signaling regulator 2
chr11_-_8892900 0.135 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5






suppression of tumorigenicity 5






chr21_-_38445470 0.134 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr5_-_139943830 0.134 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
APBB3





amyloid beta (A4) precursor protein-binding, family B, member 3





chr17_+_62223320 0.133 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chr3_-_196987309 0.133 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr17_-_42200958 0.133 ENST00000336057.5
HDAC5
histone deacetylase 5
chr5_+_43602750 0.132 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr16_+_810728 0.132 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
MSLN


mesothelin


chr17_+_74722912 0.131 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23










methyltransferase like 23










chr8_+_26240666 0.131 ENST00000523949.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr5_-_1799864 0.131 ENST00000510999.1
MRPL36
mitochondrial ribosomal protein L36
chr19_-_49016847 0.130 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr16_-_30134266 0.130 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.6 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 0.6 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 0.7 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.2 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.5 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.1 GO:2000145 regulation of cell motility(GO:2000145)
0.1 0.2 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.5 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.4 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.0 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0000050 urea cycle(GO:0000050)
0.0 0.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.4 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.0 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.3 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.0 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.0 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.0 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.0 GO:0044305 calyx of Held(GO:0044305)
0.0 0.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.8 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2 0.8 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.2 0.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.7 GO:0070905 serine binding(GO:0070905)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.7 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.0 2.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors