Motif ID: MAF_NRL

Z-value: 0.295

Transcription factors associated with MAF_NRL:

Gene SymbolEntrez IDGene Name
MAF ENSG00000178573.6 MAF
NRL ENSG00000129535.8 NRL

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFhg19_v2_chr16_-_79634595_796346200.561.2e-01Click!
NRLhg19_v2_chr14_-_24584138_245842230.462.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MAF_NRL

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_71182695 0.499 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr16_-_46782221 0.407 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr20_+_57766075 0.339 ENST00000371030.2
ZNF831
zinc finger protein 831
chr1_-_109935819 0.315 ENST00000538502.1
SORT1
sortilin 1
chr22_-_36013368 0.212 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr14_+_67999999 0.205 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr4_+_154125565 0.199 ENST00000338700.5
TRIM2
tripartite motif containing 2
chrX_-_153775426 0.193 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr16_+_56899114 0.189 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3



solute carrier family 12 (sodium/chloride transporter), member 3



chr3_+_13610216 0.186 ENST00000492059.1
FBLN2
fibulin 2
chr1_-_16344500 0.171 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
HSPB7



heat shock 27kDa protein family, member 7 (cardiovascular)



chr2_-_190044480 0.164 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr10_-_62704005 0.159 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr21_-_45671014 0.158 ENST00000436357.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr4_-_57976544 0.150 ENST00000295666.4
ENST00000537922.1
IGFBP7

insulin-like growth factor binding protein 7

chr2_+_85661918 0.143 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr16_-_30107491 0.139 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chrX_-_63005405 0.138 ENST00000374878.1
ENST00000437457.2
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr12_+_57610562 0.131 ENST00000349394.5
NXPH4
neurexophilin 4
chr22_+_31518938 0.129 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr6_+_143381979 0.123 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1






androgen-induced 1






chr6_-_166401527 0.122 ENST00000455853.1
ENST00000584911.1
LINC00473

long intergenic non-protein coding RNA 473

chr7_+_142374104 0.122 ENST00000604952.1
MTRNR2L6
MT-RNR2-like 6
chr1_-_151826173 0.121 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chrX_-_13835147 0.120 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr2_+_46769798 0.118 ENST00000238738.4
RHOQ
ras homolog family member Q
chr14_-_103989033 0.114 ENST00000553878.1
ENST00000557530.1
CKB

creatine kinase, brain

chr6_-_166401442 0.113 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr6_-_109330702 0.112 ENST00000356644.7
SESN1
sestrin 1
chr12_+_51318513 0.111 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr6_+_160693591 0.110 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr17_+_76311791 0.109 ENST00000586321.1
AC061992.2
AC061992.2
chr12_+_47610315 0.108 ENST00000548348.1
ENST00000549500.1
PCED1B

PC-esterase domain containing 1B

chr6_-_111136513 0.107 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr5_+_135364584 0.107 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr2_+_233271546 0.107 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr19_+_39759154 0.106 ENST00000331982.5
IFNL2
interferon, lambda 2
chr1_+_45274154 0.106 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19


BTB (POZ) domain containing 19


chr15_+_49715293 0.105 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr5_+_148737562 0.104 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr16_-_58004992 0.103 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1


cyclic nucleotide gated channel beta 1


chr1_-_12677714 0.100 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr6_-_116833500 0.100 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr17_+_22022437 0.100 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chr22_-_31688431 0.095 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr17_+_7253667 0.094 ENST00000570504.1
ENST00000574499.1
ACAP1

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

chr16_+_28889703 0.093 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr20_+_33759854 0.092 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr20_+_34203794 0.087 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr2_+_196521458 0.086 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_+_140019004 0.085 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
TMCO6


transmembrane and coiled-coil domains 6


chr17_-_74489215 0.084 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2


rhomboid 5 homolog 2 (Drosophila)


chr10_-_105437909 0.084 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr16_+_28889801 0.082 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_+_33264861 0.082 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr2_+_196521845 0.082 ENST00000359634.5
ENST00000412905.1
SLC39A10

solute carrier family 39 (zinc transporter), member 10

chr16_+_30960375 0.082 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chrX_-_24045303 0.081 ENST00000328046.8
KLHL15
kelch-like family member 15
chrX_+_134124968 0.080 ENST00000330288.4
SMIM10
small integral membrane protein 10
chr1_-_16345245 0.079 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr6_-_166401402 0.078 ENST00000581850.1
ENST00000444465.1
LINC00473

long intergenic non-protein coding RNA 473

chr11_+_117063295 0.078 ENST00000525478.1
ENST00000532062.1
SIDT2

SID1 transmembrane family, member 2

chr17_-_73389737 0.077 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr7_+_151791095 0.076 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr2_+_196521903 0.076 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_234296792 0.076 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chrX_-_138790348 0.076 ENST00000414978.1
ENST00000519895.1
MCF2

MCF.2 cell line derived transforming sequence

chr2_-_188419078 0.075 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr2_-_188419200 0.075 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr19_-_46285736 0.075 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK


dystrophia myotonica-protein kinase


chr4_-_186125077 0.074 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430


KIAA1430


chr16_-_1429627 0.074 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr1_-_84464780 0.074 ENST00000260505.8
TTLL7
tubulin tyrosine ligase-like family, member 7
chr19_+_52076425 0.074 ENST00000436511.2
ZNF175
zinc finger protein 175
chr12_-_719573 0.073 ENST00000397265.3
NINJ2
ninjurin 2
chr2_+_196522032 0.072 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_+_40996590 0.072 ENST00000253799.3
ENST00000452774.2
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr20_-_48782639 0.072 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr4_-_186661365 0.072 ENST00000452351.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_150264458 0.072 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr6_-_74231303 0.071 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr15_-_43877062 0.071 ENST00000381885.1
ENST00000396923.3
PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chr11_-_615570 0.070 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7


interferon regulatory factor 7


chr15_+_49715449 0.070 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr3_-_151176497 0.069 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr10_+_18549645 0.069 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_150264555 0.069 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr17_-_41739283 0.068 ENST00000393661.2
ENST00000318579.4
MEOX1

mesenchyme homeobox 1

chr19_-_46285646 0.067 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chrX_+_70316005 0.067 ENST00000374259.3
FOXO4
forkhead box O4
chr3_-_98241598 0.066 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1



claudin domain containing 1



chr2_-_220083076 0.065 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr3_+_9958758 0.065 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
IL17RC






interleukin 17 receptor C






chr7_+_151791037 0.065 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr2_+_201936707 0.064 ENST00000433898.1
ENST00000454214.1
NDUFB3

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa

chr15_+_64428529 0.064 ENST00000560861.1
SNX1
sorting nexin 1
chr10_-_50970382 0.064 ENST00000419399.1
ENST00000432695.1
OGDHL

oxoglutarate dehydrogenase-like

chr7_+_151791074 0.064 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_+_57522258 0.063 ENST00000553277.1
ENST00000243077.3
LRP1

low density lipoprotein receptor-related protein 1

chr1_+_61869748 0.063 ENST00000357977.5
NFIA
nuclear factor I/A
chr20_-_18774614 0.063 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr15_+_75118888 0.063 ENST00000395018.4
CPLX3
complexin 3
chr5_+_140019079 0.062 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr19_-_18391708 0.062 ENST00000600972.1
JUND
jun D proto-oncogene
chr3_+_179322573 0.062 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa


chr5_-_95768973 0.062 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr3_-_93781750 0.061 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr12_-_4488872 0.061 ENST00000237837.1
FGF23
fibroblast growth factor 23
chr16_-_28518153 0.061 ENST00000356897.1
IL27
interleukin 27
chr16_-_1429674 0.061 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL


unkempt family zinc finger-like


chr22_+_21369316 0.060 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6




purinergic receptor P2X, ligand-gated ion channel, 6




chr8_-_82645082 0.060 ENST00000523361.1
ZFAND1
zinc finger, AN1-type domain 1
chr12_+_118573663 0.060 ENST00000261313.2
PEBP1
phosphatidylethanolamine binding protein 1
chr3_-_160116995 0.060 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr18_-_3220106 0.059 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr19_+_10527449 0.059 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chrX_-_80377162 0.059 ENST00000430960.1
ENST00000447319.1
HMGN5

high mobility group nucleosome binding domain 5

chr3_-_98241358 0.059 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1



chr11_+_34460447 0.059 ENST00000241052.4
CAT
catalase
chr1_+_100111479 0.059 ENST00000263174.4
PALMD
palmdelphin
chr3_-_88108192 0.059 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr19_-_46146946 0.058 ENST00000536630.1
EML2
echinoderm microtubule associated protein like 2
chr11_+_112046190 0.058 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2


beta-carotene oxygenase 2


chr1_+_39876151 0.058 ENST00000530275.1
KIAA0754
KIAA0754
chr7_-_123198284 0.058 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr5_-_74062930 0.058 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
GFM2



G elongation factor, mitochondrial 2



chr15_+_59665194 0.057 ENST00000560394.1
FAM81A
family with sequence similarity 81, member A
chr12_-_57444957 0.057 ENST00000433964.1
MYO1A
myosin IA
chr5_-_146435501 0.056 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_-_10530723 0.056 ENST00000536684.1
MTRNR2L8
MT-RNR2-like 8
chr3_+_183894737 0.056 ENST00000432591.1
ENST00000431779.1
AP2M1

adaptor-related protein complex 2, mu 1 subunit

chr2_+_219135115 0.056 ENST00000248451.3
ENST00000273077.4
PNKD

paroxysmal nonkinesigenic dyskinesia

chrX_-_80377118 0.055 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chrX_-_21776281 0.055 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr4_+_22999152 0.055 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr2_-_25565377 0.055 ENST00000264709.3
ENST00000406659.3
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr15_-_43876702 0.054 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr3_+_9944492 0.054 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
IL17RE


interleukin 17 receptor E


chr5_-_146435572 0.054 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr12_+_57522692 0.053 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr14_+_23654525 0.052 ENST00000399910.1
ENST00000492621.1
C14orf164

chromosome 14 open reading frame 164

chr15_-_52587945 0.052 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr14_+_21492331 0.052 ENST00000533984.1
ENST00000532213.2
AL161668.5

AL161668.5

chr17_-_28618948 0.052 ENST00000261714.6
BLMH
bleomycin hydrolase
chr5_+_78532003 0.051 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr11_-_46142948 0.051 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr1_+_24646263 0.051 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr2_+_46770531 0.051 ENST00000482449.2
RHOQ
ras homolog family member Q
chr15_-_68498376 0.050 ENST00000540479.1
ENST00000395465.3
CALML4

calmodulin-like 4

chr17_-_42466864 0.050 ENST00000353281.4
ENST00000262407.5
ITGA2B

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

chr16_+_73420942 0.050 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1


RP11-140I24.1


chr17_+_41003166 0.050 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr6_-_74231444 0.050 ENST00000331523.2
ENST00000356303.2
EEF1A1

eukaryotic translation elongation factor 1 alpha 1

chr4_+_111397216 0.049 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr5_-_90610200 0.049 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1

RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)

RP11-213H15.4
chr2_+_120187465 0.049 ENST00000409826.1
ENST00000417645.1
TMEM37

transmembrane protein 37

chr15_+_41851211 0.049 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr7_-_32111009 0.049 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr6_-_32811771 0.048 ENST00000395339.3
ENST00000374882.3
PSMB8

proteasome (prosome, macropain) subunit, beta type, 8

chr7_-_38289173 0.048 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr7_+_26438187 0.048 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5





AC004540.5





chr17_+_48172639 0.048 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr2_-_163100045 0.048 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr14_-_75536182 0.048 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr9_+_139557360 0.048 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7


EGF-like-domain, multiple 7


chr10_+_88428370 0.048 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr7_+_99816859 0.047 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr19_-_46145696 0.047 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr2_-_163099885 0.047 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr5_-_79946820 0.047 ENST00000604882.1
MTRNR2L2
MT-RNR2-like 2
chr4_+_117220016 0.047 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr14_-_23058063 0.046 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1


defender against cell death 1


chr16_+_73266661 0.046 ENST00000561802.1
AC140912.1
AC140912.1
chr3_+_183894566 0.046 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_153517473 0.046 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr14_+_77787227 0.046 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1






glutathione S-transferase zeta 1






chr12_+_117013656 0.046 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr17_+_74536115 0.046 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr1_+_100111580 0.045 ENST00000605497.1
PALMD
palmdelphin
chr18_-_65184217 0.045 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr22_-_39151995 0.045 ENST00000405018.1
ENST00000438058.1
SUN2

Sad1 and UNC84 domain containing 2

chr3_-_126373929 0.045 ENST00000523403.1
ENST00000524230.2
TXNRD3

thioredoxin reductase 3

chr12_+_57522439 0.045 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr3_+_9958870 0.045 ENST00000413608.1
IL17RC
interleukin 17 receptor C
chr11_-_914812 0.044 ENST00000533059.1
CHID1
chitinase domain containing 1
chr11_-_77791156 0.044 ENST00000281031.4
NDUFC2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
chr14_+_69865401 0.044 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9


solute carrier family 39, member 9


chr1_-_149814478 0.044 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr9_+_139746792 0.044 ENST00000317446.2
ENST00000445819.1
MAMDC4

MAM domain containing 4

chr2_-_71357344 0.044 ENST00000494660.2
ENST00000244217.5
ENST00000486135.1
MCEE


methylmalonyl CoA epimerase


chr22_-_39150947 0.044 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2



Sad1 and UNC84 domain containing 2



chr4_+_175205038 0.044 ENST00000457424.2
ENST00000514712.1
CEP44

centrosomal protein 44kDa

chr20_+_34802295 0.043 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr11_+_28129795 0.043 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr15_-_67813924 0.043 ENST00000559298.1
IQCH-AS1
IQCH antisense RNA 1
chr19_-_39735646 0.043 ENST00000413851.2
IFNL3
interferon, lambda 3
chr7_+_132937820 0.043 ENST00000393161.2
ENST00000253861.4
EXOC4

exocyst complex component 4

chr3_-_156534754 0.043 ENST00000472943.1
ENST00000473352.1
LINC00886

long intergenic non-protein coding RNA 886

chr22_-_39151947 0.042 ENST00000216064.4
SUN2
Sad1 and UNC84 domain containing 2
chr1_+_163291680 0.042 ENST00000450453.2
ENST00000524800.1
ENST00000442820.1
ENST00000367900.3
NUF2



NUF2, NDC80 kinetochore complex component




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0060437 lung growth(GO:0060437) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.0 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.0 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME_SIGNAL_AMPLIFICATION Genes involved in Signal amplification
0.0 0.2 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2