Motif ID: MAFF_MAFG

Z-value: 0.832

Transcription factors associated with MAFF_MAFG:

Gene SymbolEntrez IDGene Name
MAFF ENSG00000185022.7 MAFF
MAFG ENSG00000197063.6 MAFG

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFFhg19_v2_chr22_+_38597889_38598021-0.836.0e-03Click!
MAFGhg19_v2_chr17_-_79881408_79881423-0.761.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MAFF_MAFG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_19796381 1.548 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL


lipoprotein lipase


chr9_-_34710066 1.522 ENST00000378792.1
ENST00000259607.2
CCL21

chemokine (C-C motif) ligand 21

chr2_+_211421262 1.063 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr8_+_26240414 0.975 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr2_+_74648848 0.925 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chrX_-_107019181 0.793 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3



TSC22 domain family, member 3



chr16_-_25122785 0.778 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1

RP11-449H11.1

chr11_+_62652649 0.761 ENST00000539507.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr16_-_25122735 0.726 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr6_+_80816342 0.698 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB


branched chain keto acid dehydrogenase E1, beta polypeptide


chr11_+_110225855 0.653 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1

RP11-347E10.1

chr15_+_90895471 0.633 ENST00000354377.3
ENST00000379090.5
ZNF774

zinc finger protein 774

chr12_-_752786 0.604 ENST00000433832.2
ENST00000542920.1
NINJ2

ninjurin 2

chr11_-_125932685 0.601 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr11_-_94965667 0.595 ENST00000542176.1
ENST00000278499.2
SESN3

sestrin 3

chr12_+_57522692 0.546 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr3_-_142720267 0.512 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr5_+_130506475 0.504 ENST00000379380.4
LYRM7
LYR motif containing 7
chr11_-_85376121 0.498 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr1_+_110210644 0.479 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
GSTM2







glutathione S-transferase mu 2 (muscle)







chr6_-_109330702 0.457 ENST00000356644.7
SESN1
sestrin 1
chr4_+_154125565 0.454 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr12_+_51318513 0.449 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr11_+_114271251 0.446 ENST00000375490.5
RBM7
RNA binding motif protein 7
chrX_-_133931164 0.444 ENST00000370790.1
ENST00000298090.6
FAM122B

family with sequence similarity 122B

chr11_+_114271314 0.442 ENST00000541475.1
RBM7
RNA binding motif protein 7
chr4_+_40337340 0.427 ENST00000310169.2
CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr10_-_134145321 0.423 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
STK32C



serine/threonine kinase 32C



chr9_+_114423615 0.415 ENST00000374293.4
GNG10
guanine nucleotide binding protein (G protein), gamma 10
chr18_+_32290218 0.411 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr12_+_56862301 0.411 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chrX_-_63005405 0.409 ENST00000374878.1
ENST00000437457.2
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr5_+_140019079 0.407 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr1_+_196788887 0.405 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr18_+_32173276 0.403 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr18_-_55253871 0.388 ENST00000382873.3
FECH
ferrochelatase
chr12_+_57522439 0.386 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr10_-_90751038 0.385 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr4_-_187517928 0.384 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr11_+_114270752 0.368 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr5_-_149535421 0.363 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr7_-_17980091 0.356 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13


sorting nexin 13


chr7_-_86849883 0.352 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr2_+_46844290 0.348 ENST00000238892.3
CRIPT
cysteine-rich PDZ-binding protein
chr18_+_11851383 0.347 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr3_+_150264555 0.343 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr9_-_139948468 0.339 ENST00000312665.5
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chrX_-_55187588 0.338 ENST00000472571.2
ENST00000332132.4
ENST00000425133.2
ENST00000358460.4
FAM104B



family with sequence similarity 104, member B



chr11_-_33183048 0.337 ENST00000438862.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr11_+_114271367 0.328 ENST00000544582.1
ENST00000545678.1
RBM7

RNA binding motif protein 7

chr6_+_150070857 0.327 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr20_+_12989596 0.326 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr3_+_150264458 0.323 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr15_-_96590126 0.321 ENST00000561051.1
RP11-4G2.1
RP11-4G2.1
chr9_-_34376851 0.318 ENST00000297625.7
KIAA1161
KIAA1161
chr14_+_32798547 0.316 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr8_+_94712732 0.305 ENST00000518322.1
FAM92A1
family with sequence similarity 92, member A1
chr1_+_240408560 0.303 ENST00000441342.1
ENST00000545751.1
FMN2

formin 2

chr6_+_150920999 0.302 ENST00000367328.1
ENST00000367326.1
PLEKHG1

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

chrX_+_155110956 0.301 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7


vesicle-associated membrane protein 7


chr7_+_5465382 0.301 ENST00000609130.1
RP11-1275H24.2
RP11-1275H24.2
chr11_+_72983246 0.294 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_-_68962744 0.292 ENST00000525124.1
DEPDC1
DEP domain containing 1
chr17_+_60758814 0.290 ENST00000579432.1
ENST00000446119.2
MRC2

mannose receptor, C type 2

chr17_-_76899275 0.290 ENST00000322630.2
ENST00000586713.1
DDC8

Protein DDC8 homolog

chr11_-_114271139 0.286 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr1_-_238108575 0.285 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr15_-_49912944 0.283 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr19_+_10736183 0.279 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
SLC44A2


solute carrier family 44 (choline transporter), member 2


chr2_-_190044480 0.279 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr10_+_85899196 0.277 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr10_+_124030819 0.277 ENST00000260723.4
ENST00000368994.2
BTBD16

BTB (POZ) domain containing 16

chr17_-_76921459 0.273 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr16_-_1429627 0.272 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr5_+_94890840 0.271 ENST00000504763.1
ARSK
arylsulfatase family, member K
chrX_+_69501943 0.270 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41


RAB41, member RAS oncogene family


chr12_+_48592134 0.267 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr12_-_10282836 0.266 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chr20_-_56195449 0.265 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr6_+_160542821 0.264 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr15_-_31521567 0.263 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2


RP11-16E12.2


chr6_-_88299678 0.259 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr19_-_49955096 0.256 ENST00000595550.1
PIH1D1
PIH1 domain containing 1
chr6_+_31638156 0.253 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr12_-_6772249 0.251 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4




inhibitor of growth family, member 4




chrX_-_55187531 0.249 ENST00000489298.1
ENST00000477847.2
FAM104B

family with sequence similarity 104, member B

chr18_-_55253830 0.247 ENST00000591215.1
FECH
ferrochelatase
chr12_+_64798095 0.247 ENST00000332707.5
XPOT
exportin, tRNA
chr3_+_108308513 0.243 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr7_+_151791074 0.240 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr3_-_125802765 0.240 ENST00000514891.1
ENST00000512470.1
ENST00000504035.1
ENST00000360370.4
ENST00000513723.1
ENST00000510651.1
ENST00000514333.1
SLC41A3






solute carrier family 41, member 3






chr19_-_49955050 0.235 ENST00000262265.5
PIH1D1
PIH1 domain containing 1
chr11_-_914812 0.235 ENST00000533059.1
CHID1
chitinase domain containing 1
chr18_+_9913977 0.232 ENST00000400000.2
ENST00000340541.4
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr2_+_128458514 0.232 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr3_+_23847394 0.231 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr12_-_71533055 0.231 ENST00000552128.1
TSPAN8
tetraspanin 8
chr3_-_176914238 0.231 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr15_-_49912987 0.229 ENST00000560246.1
ENST00000558594.1
FAM227B

family with sequence similarity 227, member B

chr1_-_54872059 0.227 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr1_+_17516275 0.227 ENST00000412427.1
RP11-380J14.1
RP11-380J14.1
chr16_-_18801643 0.226 ENST00000322989.4
ENST00000563390.1
RPS15A

ribosomal protein S15a

chr22_+_44319648 0.225 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr12_+_47610315 0.224 ENST00000548348.1
ENST00000549500.1
PCED1B

PC-esterase domain containing 1B

chr4_+_152020789 0.223 ENST00000512690.1
ENST00000508783.1
ENST00000512797.1
ENST00000507327.1
ENST00000515792.1
ENST00000506126.1
RPS3A





ribosomal protein S3A





chr6_+_160542870 0.216 ENST00000324965.4
ENST00000457470.2
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr13_+_44453688 0.214 ENST00000425906.1
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr10_+_26727125 0.212 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_+_70876926 0.210 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr7_-_40174201 0.207 ENST00000306984.6
MPLKIP
M-phase specific PLK1 interacting protein
chr1_+_110254850 0.207 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
GSTM5


glutathione S-transferase mu 5


chr10_-_124713842 0.207 ENST00000481909.1
C10orf88
chromosome 10 open reading frame 88
chr2_+_63816295 0.206 ENST00000539945.1
ENST00000544381.1
MDH1

malate dehydrogenase 1, NAD (soluble)

chr20_+_12989822 0.204 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr15_-_49913126 0.204 ENST00000561064.1
ENST00000299338.6
FAM227B

family with sequence similarity 227, member B

chr16_-_71918033 0.203 ENST00000425432.1
ENST00000313565.6
ENST00000568666.1
ENST00000562797.1
ENST00000564134.1
ZNF821




zinc finger protein 821




chr7_+_100199800 0.200 ENST00000223061.5
PCOLCE
procollagen C-endopeptidase enhancer
chr2_+_120189422 0.199 ENST00000306406.4
TMEM37
transmembrane protein 37
chr11_-_34938039 0.199 ENST00000395787.3
APIP
APAF1 interacting protein
chr16_-_18801582 0.198 ENST00000565420.1
RPS15A
ribosomal protein S15a
chr2_+_63816269 0.197 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr11_-_62380199 0.196 ENST00000419857.1
ENST00000394773.2
EML3

echinoderm microtubule associated protein like 3

chr19_-_43702231 0.195 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr2_+_242913327 0.195 ENST00000426962.1
AC093642.3
AC093642.3
chr12_-_123215306 0.194 ENST00000356987.2
ENST00000436083.2
HCAR1

hydroxycarboxylic acid receptor 1

chr5_-_111093167 0.194 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr22_-_36600849 0.190 ENST00000429038.2
ENST00000457630.2
ENST00000419360.1
ENST00000436763.1
ENST00000404685.3
ENST00000405511.1
ENST00000352371.1
ENST00000332987.1
ENST00000449084.1
APOL4








apolipoprotein L, 4








chr17_+_27369918 0.190 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr6_+_106546808 0.189 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_150070831 0.189 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr14_-_47812321 0.188 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2


MAM domain containing glycosylphosphatidylinositol anchor 2


chr4_-_185655278 0.185 ENST00000281453.5
MLF1IP
centromere protein U
chr12_+_32655048 0.185 ENST00000427716.2
ENST00000266482.3
FGD4

FYVE, RhoGEF and PH domain containing 4

chr12_-_10282742 0.184 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A


C-type lectin domain family 7, member A


chr5_+_139027877 0.184 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr12_-_57644952 0.183 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr5_+_140019004 0.179 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
TMCO6


transmembrane and coiled-coil domains 6


chr1_+_2005425 0.177 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chrX_+_102883887 0.176 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr3_+_108308559 0.176 ENST00000486815.1
DZIP3
DAZ interacting zinc finger protein 3
chr4_-_140222358 0.175 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1


NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa


chr4_-_2243839 0.174 ENST00000511885.2
ENST00000506763.1
ENST00000514395.1
ENST00000502440.1
ENST00000243706.4
ENST00000443786.2
POLN
HAUS3




polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3




chr5_-_99870932 0.174 ENST00000504833.1
CTD-2001C12.1
CTD-2001C12.1
chr17_+_66508154 0.173 ENST00000358598.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_+_89829610 0.171 ENST00000370456.4
ENST00000535065.1
GBP6

guanylate binding protein family, member 6

chr1_-_108231101 0.170 ENST00000544443.1
ENST00000415432.2
VAV3

vav 3 guanine nucleotide exchange factor

chr17_-_28618867 0.170 ENST00000394819.3
ENST00000577623.1
BLMH

bleomycin hydrolase

chr12_-_39837192 0.167 ENST00000361961.3
ENST00000395670.3
KIF21A

kinesin family member 21A

chr17_-_28618948 0.167 ENST00000261714.6
BLMH
bleomycin hydrolase
chr16_-_24942273 0.165 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr16_+_53469525 0.163 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr2_+_242167319 0.162 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr17_+_6900201 0.161 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr3_-_111852128 0.158 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr2_+_201981527 0.157 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_+_302918 0.156 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr10_-_100174900 0.156 ENST00000370575.4
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr15_-_72668185 0.155 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr2_-_46844242 0.150 ENST00000281382.6
PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr1_+_203765437 0.149 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr9_-_26892765 0.149 ENST00000520187.1
ENST00000333916.5
CAAP1

caspase activity and apoptosis inhibitor 1

chr15_-_100258029 0.147 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr2_-_86094764 0.147 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr15_+_49913175 0.146 ENST00000403028.3
DTWD1
DTW domain containing 1
chr10_-_102289611 0.146 ENST00000535773.1
ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
SEC31B
NDUFB8



SEC31 homolog B (S. cerevisiae)
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa



chr1_-_866445 0.145 ENST00000598827.1
AL645608.1
Uncharacterized protein
chr5_-_94890648 0.145 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
TTC37


tetratricopeptide repeat domain 37


chr6_+_31637944 0.145 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr5_-_111093081 0.145 ENST00000453526.2
ENST00000509427.1
NREP

neuronal regeneration related protein

chr4_+_57843876 0.145 ENST00000450656.1
ENST00000381227.1
POLR2B

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

chr16_-_15982440 0.144 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
FOPNL






FGFR1OP N-terminal like






chr10_-_105218645 0.144 ENST00000329905.5
CALHM1
calcium homeostasis modulator 1
chr11_-_915012 0.144 ENST00000449825.1
ENST00000533056.1
CHID1

chitinase domain containing 1

chr13_+_108921977 0.142 ENST00000430559.1
ENST00000375887.4
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr19_-_23456996 0.141 ENST00000594653.1
RP11-15H20.7
RP11-15H20.7
chr6_-_43197189 0.140 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
DNPH1


2'-deoxynucleoside 5'-phosphate N-hydrolase 1


chr2_+_172864490 0.140 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr12_-_39836772 0.139 ENST00000541463.2
ENST00000361418.5
ENST00000544797.2
KIF21A


kinesin family member 21A


chr1_+_203830703 0.136 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr2_-_220108309 0.135 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chrX_+_154254960 0.135 ENST00000369498.3
FUNDC2
FUN14 domain containing 2
chr1_-_110283138 0.135 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr11_-_914682 0.134 ENST00000323541.7
CHID1
chitinase domain containing 1
chr6_-_112081113 0.134 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr7_+_139025875 0.134 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr3_-_9885626 0.133 ENST00000424438.1
ENST00000433555.1
ENST00000427174.1
ENST00000418713.1
ENST00000433535.2
ENST00000383820.5
ENST00000433972.1
RPUSD3






RNA pseudouridylate synthase domain containing 3






chr3_-_119379719 0.133 ENST00000493094.1
POPDC2
popeye domain containing 2
chr14_-_75530693 0.130 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1




acylphosphatase 1, erythrocyte (common) type




chr10_+_88428206 0.130 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr5_-_90610200 0.127 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1

RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)

RP11-213H15.4
chr12_-_75784669 0.127 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
CAPS2



calcyphosine 2



chr13_+_44453969 0.127 ENST00000325686.6
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr3_-_3221358 0.126 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN



cereblon



chr2_-_95831158 0.126 ENST00000447814.1
ZNF514
zinc finger protein 514
chr12_+_133613937 0.125 ENST00000539354.1
ENST00000542874.1
ENST00000438628.2
ZNF84


zinc finger protein 84


chr10_+_73975742 0.125 ENST00000299381.4
ANAPC16
anaphase promoting complex subunit 16
chr6_-_43478239 0.125 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr2_-_11484710 0.125 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr5_+_70883178 0.124 ENST00000323375.8
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr10_-_73497581 0.124 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:2000547 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4 1.1 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.2 1.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890) chylomicron remodeling(GO:0034371)
0.2 0.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.4 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.1 0.5 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.7 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.8 GO:0060356 leucine import(GO:0060356)
0.1 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.6 GO:0070541 response to platinum ion(GO:0070541)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.8 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.3 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.6 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.0 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.0 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.0 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.0 GO:0044010 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 1.5 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0017129 triglyceride binding(GO:0017129)
0.3 0.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.3 1.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.7 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 0.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.6 GO:0004325 ferrochelatase activity(GO:0004325)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.4 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 1.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.6 GO:0004568 chitinase activity(GO:0004568)
0.0 0.7 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:1903136 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases