Motif ID: KLF6

Z-value: 0.835


Transcription factors associated with KLF6:

Gene SymbolEntrez IDGene Name
KLF6 ENSG00000067082.10 KLF6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827371_38273860.599.3e-02Click!


Activity profile for motif KLF6.

activity profile for motif KLF6


Sorted Z-values histogram for motif KLF6

Sorted Z-values for motif KLF6



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_70142232 1.537 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr2_+_70142189 1.393 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr9_+_100174344 1.119 ENST00000422139.2
TDRD7
tudor domain containing 7
chr5_+_40679584 1.077 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr19_+_45504688 1.013 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr17_-_73874654 0.888 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr6_+_83073952 0.845 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr2_-_220408430 0.788 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr1_+_151254738 0.735 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687


zinc finger protein 687


chr5_-_176924562 0.731 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7






PDZ and LIM domain 7 (enigma)






chr20_+_48807351 0.715 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr1_+_156698743 0.667 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_+_94706973 0.644 ENST00000536741.1
KDM4D
lysine (K)-specific demethylase 4D
chr2_-_217236750 0.629 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr11_+_94706804 0.618 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr2_+_7005959 0.584 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr9_+_34989638 0.565 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr18_+_3449821 0.546 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr18_+_3449695 0.538 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr7_+_143078652 0.537 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr9_+_35605274 0.525 ENST00000336395.5
TESK1
testis-specific kinase 1
chr19_-_40931891 0.516 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr16_+_3070313 0.492 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_+_3070356 0.489 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr8_-_145013711 0.482 ENST00000345136.3
PLEC
plectin
chr16_-_75299845 0.480 ENST00000535626.2
BCAR1
breast cancer anti-estrogen resistance 1
chr1_+_154297988 0.479 ENST00000368487.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr3_+_50192537 0.466 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192457 0.453 ENST00000414301.1
ENST00000450338.1
SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr3_+_50192499 0.453 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_-_168006324 0.446 ENST00000522176.1
PANK3
pantothenate kinase 3
chr7_+_143079000 0.438 ENST00000392910.2
ZYX
zyxin
chr17_+_6926381 0.435 ENST00000576705.1
BCL6B
B-cell CLL/lymphoma 6, member B
chr17_+_43299156 0.429 ENST00000331495.3
FMNL1
formin-like 1
chr17_+_6926339 0.424 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr19_+_1249869 0.417 ENST00000591446.2
MIDN
midnolin
chr6_+_36164487 0.413 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr4_+_184426147 0.408 ENST00000302327.3
ING2
inhibitor of growth family, member 2
chr11_-_72353451 0.405 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr6_+_32811885 0.402 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1




PSMB9
TAP1 and PSMB8 antisense RNA 1




proteasome (prosome, macropain) subunit, beta type, 9
chr6_+_31588478 0.400 ENST00000376007.4
ENST00000376033.2
PRRC2A

proline-rich coiled-coil 2A

chr11_+_45868957 0.396 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr17_+_43299241 0.392 ENST00000328118.3
FMNL1
formin-like 1
chr1_+_169075554 0.388 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr16_+_69600209 0.386 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr16_+_69599861 0.380 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_40273348 0.379 ENST00000225916.5
KAT2A
K(lysine) acetyltransferase 2A
chr1_+_157963063 0.374 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL


kin of IRRE like (Drosophila)


chr9_-_130742792 0.372 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr19_+_50094866 0.365 ENST00000418929.2
PRR12
proline rich 12
chr3_+_50192833 0.359 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_+_41777927 0.357 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr8_-_145018905 0.353 ENST00000398774.2
PLEC
plectin
chr1_+_157963391 0.350 ENST00000359209.6
ENST00000416935.2
KIRREL

kin of IRRE like (Drosophila)

chr17_+_79008940 0.346 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2







BAI1-associated protein 2







chr19_+_13049413 0.346 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr12_+_79258547 0.343 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_68150744 0.336 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr12_+_79258444 0.328 ENST00000261205.4
SYT1
synaptotagmin I
chr2_+_220408724 0.327 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198


transmembrane protein 198


chr1_+_160175166 0.323 ENST00000368077.1
PEA15
phosphoprotein enriched in astrocytes 15
chr12_+_122064673 0.320 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr16_+_69599899 0.313 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_160175117 0.307 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr11_-_3862059 0.307 ENST00000396978.1
RHOG
ras homolog family member G
chr17_+_42634844 0.305 ENST00000315323.3
FZD2
frizzled family receptor 2
chr14_-_23451845 0.302 ENST00000262713.2
AJUBA
ajuba LIM protein
chr2_+_170683942 0.300 ENST00000272793.5
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr3_+_159481464 0.299 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr20_-_30795511 0.291 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr19_+_8455200 0.291 ENST00000601897.1
ENST00000594216.1
RAB11B

RAB11B, member RAS oncogene family

chr2_-_97535708 0.284 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_+_160175201 0.284 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr7_-_72936608 0.281 ENST00000404251.1
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr17_-_41623691 0.281 ENST00000545954.1
ETV4
ets variant 4
chr10_+_102672712 0.281 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A


family with sequence similarity 178, member A


chr19_+_34287174 0.276 ENST00000587559.1
ENST00000588637.1
KCTD15

potassium channel tetramerization domain containing 15

chr19_+_54372877 0.275 ENST00000414489.1
MYADM
myeloid-associated differentiation marker
chr11_-_62313090 0.274 ENST00000528508.1
ENST00000533365.1
AHNAK

AHNAK nucleoprotein

chr14_-_62162541 0.272 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr2_-_73511407 0.270 ENST00000520530.2
FBXO41
F-box protein 41
chr3_+_112280857 0.269 ENST00000492406.1
ENST00000468642.1
SLC35A5

solute carrier family 35, member A5

chr11_-_78128811 0.268 ENST00000530915.1
ENST00000361507.4
GAB2

GRB2-associated binding protein 2

chr14_-_82000140 0.264 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr16_+_69600058 0.263 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_-_41623716 0.261 ENST00000319349.5
ETV4
ets variant 4
chr21_-_35987438 0.261 ENST00000313806.4
RCAN1
regulator of calcineurin 1
chr2_+_170683979 0.260 ENST00000418381.1
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr4_-_39529049 0.260 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH


UDP-glucose 6-dehydrogenase


chr5_+_133861339 0.260 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr10_+_103825080 0.258 ENST00000299238.5
HPS6
Hermansky-Pudlak syndrome 6
chr11_-_64545941 0.257 ENST00000377387.1
SF1
splicing factor 1
chr5_+_38845960 0.257 ENST00000502536.1
OSMR
oncostatin M receptor
chr2_-_220408260 0.257 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr9_-_6645628 0.253 ENST00000321612.6
GLDC
glycine dehydrogenase (decarboxylating)
chr19_+_54372693 0.253 ENST00000391768.2
MYADM
myeloid-associated differentiation marker
chr7_-_72936531 0.253 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr6_+_32811861 0.252 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr5_+_109025067 0.247 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_-_1928621 0.246 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr11_-_65429891 0.245 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr22_+_38321840 0.243 ENST00000454685.1
MICALL1
MICAL-like 1
chr10_+_72972281 0.243 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr19_-_42758040 0.241 ENST00000593944.1
ERF
Ets2 repressor factor
chr11_+_100558384 0.240 ENST00000524892.2
ENST00000298815.8
ARHGAP42

Rho GTPase activating protein 42

chr1_+_110577229 0.240 ENST00000369795.3
ENST00000369794.2
STRIP1

striatin interacting protein 1

chr11_+_64052944 0.238 ENST00000535675.1
ENST00000543383.1
GPR137

G protein-coupled receptor 137

chr10_-_101380121 0.235 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr2_-_219433014 0.234 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37




ubiquitin specific peptidase 37




chr1_-_38325256 0.232 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr11_-_19263145 0.231 ENST00000532666.1
ENST00000527884.1
E2F8

E2F transcription factor 8

chr1_+_155293702 0.230 ENST00000368347.4
RUSC1
RUN and SH3 domain containing 1
chr19_-_14629224 0.229 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_+_46131912 0.223 ENST00000584634.1
ENST00000580050.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr1_-_221915418 0.221 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chr13_-_45151259 0.220 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr12_+_57482665 0.219 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_-_41196458 0.208 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr8_-_144890847 0.207 ENST00000531942.1
SCRIB
scribbled planar cell polarity protein
chr20_-_40247133 0.206 ENST00000373233.3
ENST00000309279.7
CHD6

chromodomain helicase DNA binding protein 6

chr14_+_75230011 0.205 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLPM1


YLP motif containing 1


chr19_-_41196534 0.204 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr19_-_15560730 0.203 ENST00000389282.4
ENST00000263381.7
WIZ

widely interspaced zinc finger motifs

chr19_-_42724261 0.202 ENST00000595337.1
DEDD2
death effector domain containing 2
chr2_+_111878483 0.202 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chr11_+_65686728 0.202 ENST00000312515.2
ENST00000525501.1
DRAP1

DR1-associated protein 1 (negative cofactor 2 alpha)

chr5_-_107717058 0.200 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr1_+_198126209 0.200 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr17_+_46132037 0.198 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1


nuclear factor, erythroid 2-like 1


chr1_-_44497118 0.197 ENST00000537678.1
ENST00000466926.1
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr20_+_49348109 0.195 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr5_+_56111361 0.195 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr1_+_32538520 0.194 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
TMEM39B



transmembrane protein 39B



chr16_+_75033210 0.193 ENST00000566250.1
ENST00000567962.1
ZNRF1

zinc and ring finger 1, E3 ubiquitin protein ligase

chr17_-_7297519 0.191 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chr11_+_65686802 0.191 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_13906250 0.190 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr11_+_65480222 0.189 ENST00000534681.1
KAT5
K(lysine) acetyltransferase 5
chr19_+_54372639 0.189 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr19_+_42788172 0.188 ENST00000160740.3
CIC
capicua transcriptional repressor
chr1_-_226924980 0.186 ENST00000272117.3
ITPKB
inositol-trisphosphate 3-kinase B
chr12_-_90103077 0.186 ENST00000551310.1
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr16_+_30935896 0.185 ENST00000562319.1
ENST00000380310.2
FBXL19

F-box and leucine-rich repeat protein 19

chr6_+_41514305 0.184 ENST00000409208.1
ENST00000373057.3
FOXP4

forkhead box P4

chr2_+_24714729 0.183 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr18_+_55102917 0.183 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr1_-_228296956 0.181 ENST00000366744.1
ENST00000348259.5
ENST00000366747.3
ENST00000366746.3
ENST00000295008.4
ENST00000336520.3
ENST00000366731.5
ENST00000411464.2
ENST00000457264.1
ENST00000336300.5
ENST00000430433.1
ENST00000391867.3
MRPL55











mitochondrial ribosomal protein L55











chr4_+_26862400 0.181 ENST00000467011.1
ENST00000412829.2
STIM2

stromal interaction molecule 2

chr2_+_241375069 0.180 ENST00000264039.2
GPC1
glypican 1
chr11_-_19262486 0.180 ENST00000250024.4
E2F8
E2F transcription factor 8
chr1_-_44497024 0.179 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr8_+_74206829 0.179 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr14_+_23341513 0.179 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr11_-_64578188 0.179 ENST00000312049.6
ENST00000443283.1
ENST00000315422.4
ENST00000394374.2
MEN1



multiple endocrine neoplasia I



chr1_+_32538492 0.179 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr16_+_68678739 0.178 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr12_-_96184913 0.178 ENST00000538383.1
NTN4
netrin 4
chr11_-_9482010 0.177 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr19_+_54641444 0.177 ENST00000221232.5
ENST00000358389.3
CNOT3

CCR4-NOT transcription complex, subunit 3

chr17_+_37026284 0.176 ENST00000433206.2
ENST00000435347.3
LASP1

LIM and SH3 protein 1

chr17_+_38465441 0.175 ENST00000577646.1
ENST00000254066.5
RARA

retinoic acid receptor, alpha

chr9_+_2017063 0.175 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_-_30134266 0.175 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3

chr11_+_64053005 0.174 ENST00000538032.1
GPR137
G protein-coupled receptor 137
chr15_-_76352069 0.173 ENST00000305435.10
ENST00000563910.1
NRG4

neuregulin 4

chr3_-_53080047 0.170 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr15_+_96873921 0.170 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_67211263 0.170 ENST00000393893.1
CORO1B
coronin, actin binding protein, 1B
chr14_-_81687575 0.169 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr5_-_142782862 0.168 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_7297833 0.168 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr16_-_28222797 0.167 ENST00000569951.1
ENST00000565698.1
XPO6

exportin 6

chr12_+_57482877 0.167 ENST00000342556.6
ENST00000357680.4
NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2)

chr12_+_52445191 0.166 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr2_+_220299547 0.166 ENST00000312358.7
SPEG
SPEG complex locus
chr1_+_173837488 0.166 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37


zinc finger and BTB domain containing 37


chr6_+_37787704 0.165 ENST00000474522.1
ZFAND3
zinc finger, AN1-type domain 3
chr15_-_74726283 0.165 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr11_+_64053311 0.164 ENST00000540370.1
GPR137
G protein-coupled receptor 137
chr16_+_68679193 0.163 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_-_5978090 0.163 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RANBP3






RAN binding protein 3






chr10_+_99473455 0.161 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chr2_+_150187020 0.160 ENST00000334166.4
LYPD6
LY6/PLAUR domain containing 6
chr5_-_142783365 0.160 ENST00000508760.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_16395455 0.159 ENST00000409083.3
FAM211A
family with sequence similarity 211, member A
chr1_+_198126093 0.159 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7


NIMA-related kinase 7


chr9_-_117267717 0.159 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr18_-_72265035 0.159 ENST00000585279.1
ENST00000580048.1
LINC00909

long intergenic non-protein coding RNA 909

chr19_-_10444188 0.158 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr19_+_56652643 0.157 ENST00000586123.1
ZNF444
zinc finger protein 444
chr17_+_46131843 0.156 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr16_+_68678892 0.155 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr4_-_78740769 0.154 ENST00000512485.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr5_+_139493665 0.153 ENST00000331327.3
PURA
purine-rich element binding protein A
chr19_-_44259136 0.153 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr6_-_31864977 0.153 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr12_+_132312931 0.152 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17


matrix metallopeptidase 17 (membrane-inserted)


chr1_+_155036204 0.151 ENST00000556931.1
ENST00000368409.3
ENST00000359751.4
ENST00000427683.2
ENST00000505139.1
EFNA3
EFNA4


EFNA3
ephrin-A3
ephrin-A4


Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chr19_-_5978144 0.150 ENST00000340578.6
ENST00000541471.1
ENST00000591736.1
ENST00000587479.1
RANBP3



RAN binding protein 3



chr7_+_92158083 0.150 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RBM48


RNA binding motif protein 48



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2 0.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 1.1 GO:2000416 regulation of eosinophil migration(GO:2000416)
0.1 1.7 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.4 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.5 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 1.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.6 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.4 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.9 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847) negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 1.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.8 GO:0051014 actin filament severing(GO:0051014)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 1.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.5 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.9 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.1 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.0 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.0 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.0 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.9 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.0 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.0 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 2.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_PROSTANOID_LIGAND_RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.1 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_BOTULINUM_NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants