Motif ID: KLF14_SP8

Z-value: 0.556

Transcription factors associated with KLF14_SP8:

Gene SymbolEntrez IDGene Name
KLF14 ENSG00000174595.4 KLF14
SP8 ENSG00000164651.12 SP8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF14hg19_v2_chr7_-_130418888_1304188880.646.2e-02Click!
SP8hg19_v2_chr7_-_20826504_20826526-0.068.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of KLF14_SP8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_46299199 0.830 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr11_-_94964354 0.750 ENST00000536441.1
SESN3
sestrin 3
chr11_-_94964210 0.741 ENST00000416495.2
ENST00000393234.1
SESN3

sestrin 3

chr17_+_7184986 0.623 ENST00000317370.8
ENST00000571308.1
SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr9_+_33264861 0.549 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr9_+_33265011 0.546 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr9_-_33264676 0.534 ENST00000472232.3
ENST00000379704.2
BAG1

BCL2-associated athanogene

chr14_-_74551096 0.518 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr19_-_46000251 0.513 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2


reticulon 2


chr10_+_74033672 0.486 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr14_-_74551172 0.476 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr9_-_33264557 0.444 ENST00000473781.1
ENST00000488499.1
BAG1

BCL2-associated athanogene

chr8_-_93978357 0.442 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK





triple QxxK/R motif containing





chrX_-_140271249 0.407 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr12_+_53400176 0.400 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B




eukaryotic translation initiation factor 4B




chr1_-_26232522 0.398 ENST00000399728.1
STMN1
stathmin 1
chr2_+_30369807 0.389 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
YPEL5


yippee-like 5 (Drosophila)


chrX_+_30671476 0.378 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr11_+_7534999 0.367 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr2_+_30369859 0.366 ENST00000402003.3
YPEL5
yippee-like 5 (Drosophila)
chr12_+_53399942 0.352 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chr22_+_31608219 0.348 ENST00000406516.1
ENST00000444929.2
ENST00000331728.4
LIMK2


LIM domain kinase 2


chr8_-_93978333 0.346 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK


triple QxxK/R motif containing


chr11_-_63684316 0.326 ENST00000301459.4
RCOR2
REST corepressor 2
chr15_-_40401062 0.322 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr9_+_133320301 0.320 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr6_-_33285505 0.318 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr9_+_133320339 0.315 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
ASS1


argininosuccinate synthase 1


chr8_-_93978309 0.313 ENST00000517858.1
ENST00000378861.5
TRIQK

triple QxxK/R motif containing

chr5_-_93447333 0.303 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A


family with sequence similarity 172, member A


chr8_-_93978346 0.301 ENST00000523580.1
TRIQK
triple QxxK/R motif containing
chrX_+_67913471 0.300 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr17_-_26903900 0.300 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr2_+_74648848 0.294 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr17_-_49337392 0.292 ENST00000376381.2
ENST00000586178.1
MBTD1

mbt domain containing 1

chr12_-_117628253 0.287 ENST00000330622.5
FBXO21
F-box protein 21
chr20_+_34129770 0.284 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3






ERGIC and golgi 3






chr12_+_57610562 0.281 ENST00000349394.5
NXPH4
neurexophilin 4
chr8_-_93978216 0.281 ENST00000517751.1
ENST00000524107.1
TRIQK

triple QxxK/R motif containing

chr6_-_31697563 0.281 ENST00000375789.2
ENST00000416410.1
DDAH2

dimethylarginine dimethylaminohydrolase 2

chr20_-_3154162 0.277 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr15_+_83098710 0.276 ENST00000561062.1
ENST00000358583.3
GOLGA6L9

golgin A6 family-like 20

chr15_+_82722225 0.275 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr1_-_45956822 0.275 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr10_+_104678102 0.273 ENST00000433628.2
CNNM2
cyclin M2
chr12_-_117628333 0.271 ENST00000427718.2
FBXO21
F-box protein 21
chr11_-_17565947 0.271 ENST00000527020.1
ENST00000318024.4
USH1C

Usher syndrome 1C (autosomal recessive, severe)

chr1_+_45140360 0.265 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228




chromosome 1 open reading frame 228




chr3_-_160117301 0.264 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr19_-_46142362 0.264 ENST00000586770.1
ENST00000591721.1
EML2

echinoderm microtubule associated protein like 2

chr11_-_115375107 0.258 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr16_+_2198604 0.254 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr4_+_87856129 0.252 ENST00000395146.4
ENST00000507468.1
AFF1

AF4/FMR2 family, member 1

chr15_+_84904525 0.250 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr16_-_81129951 0.248 ENST00000315467.3
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr3_-_48594248 0.247 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4





chr12_-_6772249 0.246 ENST00000467678.1
ENST00000493873.1
ENST00000423703.2
ENST00000412586.2
ENST00000444704.2
ING4




inhibitor of growth family, member 4




chr14_-_21493123 0.243 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chr7_-_98030360 0.243 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr5_-_81046841 0.242 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2


single-stranded DNA binding protein 2


chr17_-_48277552 0.240 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr18_-_48723690 0.238 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr9_-_131038266 0.237 ENST00000490628.1
ENST00000421699.2
ENST00000450617.1
GOLGA2


golgin A2


chr3_+_100120441 0.235 ENST00000489752.1
LNP1
leukemia NUP98 fusion partner 1
chr3_+_154797636 0.235 ENST00000481828.1
MME
membrane metallo-endopeptidase
chr5_-_89770582 0.234 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr3_-_160117035 0.233 ENST00000489004.1
ENST00000496589.1
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr1_-_26231589 0.233 ENST00000374291.1
STMN1
stathmin 1
chr4_+_1795012 0.231 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3



fibroblast growth factor receptor 3



chr4_+_39046615 0.231 ENST00000261425.3
ENST00000508137.2
KLHL5

kelch-like family member 5

chr4_-_8160510 0.229 ENST00000407564.3
ENST00000361737.5
ENST00000296372.8
ENST00000545242.1
ENST00000546334.1
ENST00000318888.4
ENST00000428004.2
ABLIM2






actin binding LIM protein family, member 2






chr19_+_46000506 0.229 ENST00000396737.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr1_+_6845578 0.228 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr1_-_23670817 0.228 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr12_+_106696581 0.227 ENST00000547153.1
ENST00000299045.3
ENST00000546625.1
ENST00000553098.1
TCP11L2



t-complex 11, testis-specific-like 2



chr3_-_160116995 0.226 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
IFT80



intraflagellar transport 80 homolog (Chlamydomonas)



chr15_+_82555125 0.225 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr12_+_56473628 0.225 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3


v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3


chr10_+_92980517 0.225 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr1_-_24194771 0.223 ENST00000374479.3
FUCA1
fucosidase, alpha-L- 1, tissue
chr12_-_6772303 0.222 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4


inhibitor of growth family, member 4


chr12_-_68726131 0.222 ENST00000430606.2
MDM1
Mdm1 nuclear protein homolog (mouse)
chr4_-_174255536 0.221 ENST00000446922.2
HMGB2
high mobility group box 2
chr1_+_153940713 0.220 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4


cAMP responsive element binding protein 3-like 4


chr19_-_46142637 0.219 ENST00000590043.1
ENST00000589876.1
EML2

echinoderm microtubule associated protein like 2

chr1_-_23670813 0.219 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr7_+_155089486 0.218 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr19_-_46142680 0.218 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr2_+_203879568 0.215 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr12_+_25348139 0.215 ENST00000557540.2
ENST00000381356.4
LYRM5

LYR motif containing 5

chr7_+_75544466 0.214 ENST00000421059.1
ENST00000394893.1
ENST00000412521.1
ENST00000414186.1
POR



P450 (cytochrome) oxidoreductase



chr3_-_101232019 0.213 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7





SUMO1/sentrin specific peptidase 7





chr9_+_2622085 0.212 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr13_-_30424821 0.211 ENST00000380680.4
UBL3
ubiquitin-like 3
chr5_-_81046922 0.210 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr5_+_118407053 0.210 ENST00000311085.8
ENST00000539542.1
DMXL1

Dmx-like 1

chr19_+_5904866 0.208 ENST00000339485.3
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chr1_+_202995611 0.208 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr2_+_239335449 0.207 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr20_+_35201993 0.206 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chrX_+_153237740 0.206 ENST00000369982.4
TMEM187
transmembrane protein 187
chr12_+_25348186 0.206 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5






LYR motif containing 5






chr1_-_17380630 0.206 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr17_-_37382105 0.204 ENST00000333461.5
STAC2
SH3 and cysteine rich domain 2
chr1_-_45956800 0.203 ENST00000538496.1
TESK2
testis-specific kinase 2
chr8_+_15397732 0.201 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3



tumor suppressor candidate 3



chrX_-_153775760 0.200 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD


glucose-6-phosphate dehydrogenase


chr9_+_101705893 0.199 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr15_+_23255242 0.198 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr14_+_74416989 0.197 ENST00000334571.2
ENST00000554920.1
COQ6

coenzyme Q6 monooxygenase

chr11_-_568369 0.196 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr10_+_76586348 0.193 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chrX_-_153775047 0.192 ENST00000433845.1
ENST00000439227.1
G6PD

glucose-6-phosphate dehydrogenase

chr10_+_114709999 0.192 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr15_-_77197620 0.192 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr1_-_23810664 0.190 ENST00000336689.3
ENST00000437606.2
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr3_-_49142178 0.189 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS


glutaminyl-tRNA synthetase


chr4_-_174256276 0.187 ENST00000296503.5
HMGB2
high mobility group box 2
chr1_+_153940346 0.187 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4



cAMP responsive element binding protein 3-like 4



chr3_-_188665428 0.182 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr8_+_120885949 0.179 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr1_-_167522982 0.178 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr17_-_7165662 0.177 ENST00000571881.2
ENST00000360325.7
CLDN7

claudin 7

chr4_+_37978891 0.177 ENST00000446803.2
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr16_-_75018968 0.176 ENST00000262144.6
WDR59
WD repeat domain 59
chr15_+_85144217 0.176 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2









zinc finger and SCAN domain containing 2









chr4_-_174255400 0.176 ENST00000506267.1
HMGB2
high mobility group box 2
chr4_+_87856191 0.175 ENST00000503477.1
AFF1
AF4/FMR2 family, member 1
chr12_+_57522258 0.175 ENST00000553277.1
ENST00000243077.3
LRP1

low density lipoprotein receptor-related protein 1

chrX_-_131623874 0.172 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr16_+_23569021 0.170 ENST00000567212.1
ENST00000567264.1
UBFD1

ubiquitin family domain containing 1

chr12_+_49961990 0.170 ENST00000551063.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_+_153940741 0.169 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr3_+_154797877 0.169 ENST00000462745.1
ENST00000493237.1
MME

membrane metallo-endopeptidase

chr3_-_48936272 0.169 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20


solute carrier family 25 (carnitine/acylcarnitine translocase), member 20


chr1_+_20959943 0.168 ENST00000321556.4
PINK1
PTEN induced putative kinase 1
chr9_+_35161998 0.168 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B


unc-13 homolog B (C. elegans)


chr6_-_37467628 0.167 ENST00000373408.3
CCDC167
coiled-coil domain containing 167
chr4_+_159593418 0.167 ENST00000507475.1
ENST00000307738.5
ETFDH

electron-transferring-flavoprotein dehydrogenase

chr9_+_72658490 0.165 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr19_+_46003056 0.165 ENST00000401593.1
ENST00000396736.2
PPM1N

protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

chr9_+_139685782 0.164 ENST00000290079.8
ENST00000456614.2
TMEM141
RP11-216L13.17
transmembrane protein 141
RP11-216L13.17
chr9_-_116163400 0.164 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD


aminolevulinate dehydratase


chr11_+_77532233 0.163 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr16_-_67217844 0.163 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L


KIAA0895-like


chr18_+_61144160 0.162 ENST00000489441.1
ENST00000424602.1
SERPINB5

serpin peptidase inhibitor, clade B (ovalbumin), member 5

chr15_-_41166414 0.161 ENST00000220507.4
RHOV
ras homolog family member V
chr6_+_106534192 0.160 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr2_-_71454185 0.160 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr19_-_48673552 0.160 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chrX_-_153775426 0.160 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr3_+_154798162 0.159 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr19_+_49866851 0.157 ENST00000221498.2
ENST00000596402.1
DKKL1

dickkopf-like 1

chr17_-_55162360 0.157 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3

RP11-166P13.3

chr6_-_31138439 0.157 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr10_+_13142075 0.157 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN



optineurin



chr19_-_47164386 0.156 ENST00000391916.2
ENST00000410105.2
DACT3

dishevelled-binding antagonist of beta-catenin 3

chr12_-_58240470 0.155 ENST00000548823.1
ENST00000398073.2
CTDSP2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

chr1_+_203274639 0.154 ENST00000290551.4
BTG2
BTG family, member 2
chr17_-_47439437 0.154 ENST00000430262.2
ZNF652
zinc finger protein 652
chr5_-_81046904 0.153 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr12_+_57522692 0.152 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr5_+_118406796 0.151 ENST00000503802.1
DMXL1
Dmx-like 1
chr16_+_30907927 0.151 ENST00000279804.2
ENST00000395019.3
CTF1

cardiotrophin 1

chr7_+_99775366 0.150 ENST00000394018.2
ENST00000416412.1
STAG3

stromal antigen 3

chr10_+_124768482 0.150 ENST00000368869.4
ENST00000358776.4
ACADSB

acyl-CoA dehydrogenase, short/branched chain

chr19_+_1491144 0.149 ENST00000233596.3
REEP6
receptor accessory protein 6
chrX_-_131623982 0.149 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr5_-_79950775 0.149 ENST00000439211.2
DHFR
dihydrofolate reductase
chr5_-_89770171 0.149 ENST00000514906.1
MBLAC2
metallo-beta-lactamase domain containing 2
chr12_-_6579833 0.148 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr14_+_100705322 0.147 ENST00000262238.4
YY1
YY1 transcription factor
chr20_+_34204939 0.147 ENST00000454819.1
SPAG4
sperm associated antigen 4
chr4_-_129209221 0.147 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr12_-_6579808 0.147 ENST00000535180.1
ENST00000400911.3
VAMP1

vesicle-associated membrane protein 1 (synaptobrevin 1)

chr16_+_69221028 0.147 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr11_+_10772847 0.147 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr5_+_154237778 0.147 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
CNOT8


CCR4-NOT transcription complex, subunit 8


chr16_+_87425381 0.146 ENST00000268607.5
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
chr18_+_61143994 0.145 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr1_+_180601139 0.145 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr9_+_2621798 0.145 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr20_-_23402028 0.143 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB


N-ethylmaleimide-sensitive factor attachment protein, beta


chr2_-_110371664 0.143 ENST00000545389.1
ENST00000423520.1
SEPT10

septin 10

chr11_+_77532155 0.142 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC




adipogenesis associated, Mth938 domain containing




chr4_-_90758227 0.142 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA




synuclein, alpha (non A4 component of amyloid precursor)




chr6_-_110500905 0.141 ENST00000392587.2
WASF1
WAS protein family, member 1
chr8_-_134309823 0.141 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr11_+_63998198 0.141 ENST00000321460.5
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr17_-_37009882 0.140 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23




ribosomal protein L23




chr16_-_56553882 0.140 ENST00000568104.1
BBS2
Bardet-Biedl syndrome 2
chr22_+_29469100 0.139 ENST00000327813.5
ENST00000407188.1
KREMEN1

kringle containing transmembrane protein 1

chr8_+_124428959 0.139 ENST00000287387.2
ENST00000523984.1
WDYHV1

WDYHV motif containing 1

chr14_-_21493649 0.138 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr9_+_19408999 0.138 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr5_+_112312416 0.137 ENST00000389063.2
DCP2
decapping mRNA 2
chr6_-_33266687 0.137 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr10_+_120789223 0.136 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr19_-_48673580 0.136 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr16_-_81129845 0.136 ENST00000569885.1
ENST00000566566.1
GCSH

glycine cleavage system protein H (aminomethyl carrier)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.3 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.1 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 1.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.2 GO:1901983 regulation of protein acetylation(GO:1901983)
0.1 0.3 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.4 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.1 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.3 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of glycoprotein metabolic process(GO:1903019)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.1 0.2 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.2 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.0 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.0 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.4 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.1 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.0 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.0 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.0 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.1 GO:0072717 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.5 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:2000466 negative regulation of glycogen (starch) synthase activity(GO:2000466)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.0 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.2 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.0 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.0 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.0 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.0 GO:2000182 cellular response to heparin(GO:0071504) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.0 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.0 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.0 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.0 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.0 0.3 GO:0070977 bone maturation(GO:0070977)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0006550 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.0 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0061511 centriole elongation(GO:0061511)
0.0 0.0 GO:0042593 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting two-sector ATPase complex assembly(GO:0070071) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.0 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0060648 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) mammary gland specification(GO:0060594) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) mammary gland bud morphogenesis(GO:0060648) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 1.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.2 GO:0075341 host cell PML body(GO:0075341)
0.1 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.0 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0097134 cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942) cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.0 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0001740 Barr body(GO:0001740)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.7 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.5 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.4 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.3 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.6 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.3 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.0 GO:0032407 mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.0 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.0 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint