Motif ID: IRX3

Z-value: 0.789


Transcription factors associated with IRX3:

Gene SymbolEntrez IDGene Name
IRX3 ENSG00000177508.11 IRX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRX3hg19_v2_chr16_-_54320675_54320715-0.196.3e-01Click!


Activity profile for motif IRX3.

activity profile for motif IRX3


Sorted Z-values histogram for motif IRX3

Sorted Z-values for motif IRX3



Network of associatons between targets according to the STRING database.



First level regulatory network of IRX3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_35856951 3.756 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R



interleukin 7 receptor



chr10_+_91092241 2.659 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_34207295 2.289 ENST00000463941.1
ENST00000293272.3
CCL5

chemokine (C-C motif) ligand 5

chr4_-_76957214 2.075 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_-_69180012 1.867 ENST00000481498.1
GKN2
gastrokine 2
chr11_-_63330842 1.858 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr1_-_89488510 1.771 ENST00000564665.1
ENST00000370481.4
GBP3

guanylate binding protein 3

chr22_-_36556821 1.647 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3


apolipoprotein L, 3


chr17_+_38673270 1.274 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chrX_-_15683147 1.252 ENST00000380342.3
TMEM27
transmembrane protein 27
chr9_+_100174232 1.236 ENST00000355295.4
TDRD7
tudor domain containing 7
chr17_-_29641104 1.170 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr7_-_92777606 1.062 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chrX_-_15620192 1.043 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr4_+_75480629 1.023 ENST00000380846.3
AREGB
amphiregulin B
chr11_+_35201826 0.889 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr19_+_36203830 0.839 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr4_+_75310851 0.791 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr14_-_23623577 0.761 ENST00000422941.2
ENST00000453702.1
SLC7A8

solute carrier family 7 (amino acid transporter light chain, L system), member 8

chr19_-_22379753 0.758 ENST00000397121.2
ZNF676
zinc finger protein 676
chr12_+_76653611 0.741 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr6_+_71104588 0.711 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr11_+_35211429 0.642 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44


CD44 molecule (Indian blood group)


chrX_-_135962923 0.642 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr17_-_29641084 0.603 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr6_+_106988986 0.586 ENST00000457437.1
ENST00000535438.1
AIM1

absent in melanoma 1

chr19_-_54974894 0.569 ENST00000333834.4
LENG9
leukocyte receptor cluster (LRC) member 9
chr7_+_55086703 0.565 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR



epidermal growth factor receptor



chr3_+_158787041 0.533 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr22_-_29107919 0.512 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr12_+_76653682 0.504 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr16_-_65268795 0.472 ENST00000565901.1
ENST00000567058.1
RP11-256I9.2

RP11-256I9.2

chr2_+_228735763 0.453 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr1_+_156863470 0.442 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1


platelet endothelial aggregation receptor 1


chr14_-_23624511 0.437 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr13_+_76362974 0.430 ENST00000497947.2
LMO7
LIM domain 7
chr17_+_18601299 0.429 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L


tripartite motif containing 16-like


chr5_-_13944652 0.423 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr2_+_191792376 0.421 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr1_-_201438282 0.418 ENST00000367311.3
ENST00000367309.1
PHLDA3

pleckstrin homology-like domain, family A, member 3

chr4_-_84035905 0.410 ENST00000311507.4
PLAC8
placenta-specific 8
chr3_-_183543301 0.404 ENST00000318631.3
ENST00000431348.1
MAP6D1

MAP6 domain containing 1

chr3_+_171844762 0.398 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr1_+_64014588 0.395 ENST00000371086.2
ENST00000340052.3
DLEU2L

deleted in lymphocytic leukemia 2-like

chr8_+_125463048 0.391 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr2_-_166060552 0.374 ENST00000283254.7
ENST00000453007.1
SCN3A

sodium channel, voltage-gated, type III, alpha subunit

chr17_-_33760164 0.371 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12


schlafen family member 12


chr5_-_147211226 0.359 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chrX_+_15767971 0.347 ENST00000479740.1
ENST00000454127.2
CA5B

carbonic anhydrase VB, mitochondrial

chr19_+_17830051 0.341 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S



microtubule-associated protein 1S



chr4_+_100737954 0.337 ENST00000296414.7
ENST00000512369.1
DAPP1

dual adaptor of phosphotyrosine and 3-phosphoinositides

chr2_-_113594279 0.333 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr2_-_70189397 0.331 ENST00000320256.4
ASPRV1
aspartic peptidase, retroviral-like 1
chr14_+_73563735 0.325 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr6_+_126221034 0.325 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr6_-_144329531 0.323 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1



pleiomorphic adenoma gene-like 1



chr7_-_104909435 0.323 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr1_+_160175166 0.322 ENST00000368077.1
PEA15
phosphoprotein enriched in astrocytes 15
chr16_-_30621663 0.321 ENST00000287461.3
ZNF689
zinc finger protein 689
chr10_+_90660832 0.318 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr1_+_149239529 0.303 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr1_+_160175201 0.303 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chrX_+_48755202 0.299 ENST00000447146.2
ENST00000376548.5
ENST00000247140.4
PQBP1


polyglutamine binding protein 1


chr7_+_76090993 0.299 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2










deltex homolog 2 (Drosophila)










chr1_+_160175117 0.297 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr1_+_22778337 0.295 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40



zinc finger and BTB domain containing 40



chr1_+_113010056 0.291 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr16_+_22501658 0.289 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr17_-_61904420 0.289 ENST00000580272.1
FTSJ3
FtsJ homolog 3 (E. coli)
chr8_-_19459993 0.288 ENST00000454498.2
ENST00000520003.1
CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr3_-_49851313 0.286 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr22_-_50970919 0.285 ENST00000329363.4
ENST00000437588.1
ODF3B

outer dense fiber of sperm tails 3B

chr4_+_79567057 0.285 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2

long intergenic non-protein coding RNA 1094

chr2_+_101591314 0.284 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr2_+_33661382 0.283 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr15_+_52155001 0.281 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr1_+_207070775 0.280 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24


interleukin 24


chr17_-_61905005 0.277 ENST00000584574.1
ENST00000585145.1
ENST00000427159.2
FTSJ3


FtsJ homolog 3 (E. coli)


chr1_+_158985457 0.274 ENST00000567661.1
ENST00000474473.1
IFI16

interferon, gamma-inducible protein 16

chrX_-_129402857 0.273 ENST00000447817.1
ENST00000370978.4
ZNF280C

zinc finger protein 280C

chr6_+_149887377 0.271 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr6_+_10528560 0.271 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr17_+_16945820 0.270 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr7_+_120591170 0.266 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr6_-_15586238 0.262 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr3_-_122283079 0.261 ENST00000471785.1
ENST00000466126.1
PARP9

poly (ADP-ribose) polymerase family, member 9

chr11_-_57177586 0.259 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr10_+_127661942 0.259 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1


fibronectin type III and ankyrin repeat domains 1


chr15_+_67420441 0.258 ENST00000558894.1
SMAD3
SMAD family member 3
chr8_+_27631903 0.251 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr1_-_85156417 0.251 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_+_112298514 0.250 ENST00000536167.1
DDX20
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
chr4_-_103998439 0.249 ENST00000503230.1
ENST00000503818.1
SLC9B2

solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

chr3_+_52245458 0.248 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr12_-_26986076 0.248 ENST00000381340.3
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chrX_-_77150911 0.246 ENST00000373336.3
MAGT1
magnesium transporter 1
chr2_+_58655461 0.246 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr3_+_11267691 0.245 ENST00000413416.1
HRH1
histamine receptor H1
chr17_-_33760269 0.243 ENST00000452764.3
SLFN12
schlafen family member 12
chr17_-_4607335 0.242 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1



proline, glutamate and leucine rich protein 1



chr16_+_22518495 0.240 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr2_-_216878305 0.239 ENST00000263268.6
MREG
melanoregulin
chr12_+_106751436 0.237 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr12_-_6451235 0.234 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr17_-_76824975 0.232 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr1_+_100817262 0.232 ENST00000455467.1
CDC14A
cell division cycle 14A
chr8_-_50466973 0.231 ENST00000520800.1
RP11-738G5.2
Uncharacterized protein
chr12_-_100486668 0.231 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L




UHRF1 binding protein 1-like




chr4_+_123653882 0.231 ENST00000433287.1
BBS12
Bardet-Biedl syndrome 12
chr10_+_105881779 0.228 ENST00000369729.3
SFR1
SWI5-dependent recombination repair 1
chr11_+_74303612 0.225 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
POLD3


polymerase (DNA-directed), delta 3, accessory subunit


chr16_+_22524844 0.224 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
NPIPB5



nuclear pore complex interacting protein family, member B5



chr3_+_122283064 0.223 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr11_+_61891445 0.223 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr3_-_122283100 0.220 ENST00000492382.1
ENST00000462315.1
PARP9

poly (ADP-ribose) polymerase family, member 9

chr19_+_55591743 0.219 ENST00000588359.1
ENST00000245618.5
EPS8L1

EPS8-like 1

chr16_-_57836321 0.219 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
KIFC3



kinesin family member C3



chr14_+_52164820 0.217 ENST00000554167.1
FRMD6
FERM domain containing 6
chr9_-_95244781 0.214 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN



asporin



chr1_-_3566627 0.214 ENST00000419924.2
ENST00000270708.7
WRAP73

WD repeat containing, antisense to TP73

chr12_-_92536433 0.213 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr1_-_85742773 0.212 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr11_+_29181503 0.212 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chrX_-_19988382 0.211 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr21_+_45773515 0.211 ENST00000397932.2
ENST00000300481.9
TRPM2

transient receptor potential cation channel, subfamily M, member 2

chr6_+_31105426 0.210 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr18_-_46784778 0.209 ENST00000582399.1
DYM
dymeclin
chr14_-_106963409 0.205 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr2_-_3521518 0.205 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr12_-_10601963 0.204 ENST00000543893.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr7_+_37960163 0.199 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr3_-_27498235 0.198 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr11_+_17281900 0.197 ENST00000530527.1
NUCB2
nucleobindin 2
chr3_-_169487617 0.197 ENST00000330368.2
ACTRT3
actin-related protein T3
chr11_-_60010556 0.196 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr14_-_67878917 0.194 ENST00000216446.4
PLEK2
pleckstrin 2
chr9_-_136203235 0.194 ENST00000372022.4
SURF6
surfeit 6
chr6_+_127587755 0.193 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146





ring finger protein 146





chr18_-_21166841 0.193 ENST00000269228.5
NPC1
Niemann-Pick disease, type C1
chr2_-_88125471 0.192 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr7_+_13141097 0.191 ENST00000411542.1
AC011288.2
AC011288.2
chr16_+_29991673 0.190 ENST00000416441.2
TAOK2
TAO kinase 2
chr5_+_110427983 0.188 ENST00000513710.2
ENST00000505303.1
WDR36

WD repeat domain 36

chr5_+_56205081 0.187 ENST00000285947.2
ENST00000541720.1
SETD9

SET domain containing 9

chr5_+_54455946 0.186 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8


glutathione peroxidase 8 (putative)


chr1_-_85870177 0.185 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_+_22429205 0.185 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr3_+_69928256 0.185 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr6_+_28249332 0.184 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr3_+_156799587 0.184 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chrX_-_77150985 0.183 ENST00000358075.6
MAGT1
magnesium transporter 1
chr5_+_169011033 0.179 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr1_-_205091115 0.177 ENST00000264515.6
ENST00000367164.1
RBBP5

retinoblastoma binding protein 5

chr16_-_21442874 0.177 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr14_-_105487381 0.176 ENST00000392590.3
ENST00000336219.3
CDCA4

cell division cycle associated 4

chr2_+_234621551 0.176 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_+_169842707 0.173 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr13_-_88323218 0.172 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr11_+_64052692 0.171 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr17_-_47755338 0.171 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP



speckle-type POZ protein



chr12_-_11214893 0.171 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr14_-_38036271 0.170 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr13_-_46716969 0.170 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_151451707 0.169 ENST00000356517.3
AADACL2
arylacetamide deacetylase-like 2
chr13_-_34250861 0.169 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3

RP11-141M1.3

chr6_+_42584847 0.169 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr2_+_234590556 0.168 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr12_-_102224704 0.168 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr10_-_30637906 0.167 ENST00000417581.1
MTPAP
mitochondrial poly(A) polymerase
chr11_+_32851487 0.167 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr5_+_125800836 0.166 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr3_+_16306691 0.166 ENST00000285083.5
ENST00000605932.1
ENST00000435829.2
OXNAD1


oxidoreductase NAD-binding domain containing 1


chr14_+_89290965 0.166 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8







tetratricopeptide repeat domain 8







chr21_+_34697209 0.166 ENST00000270139.3
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr15_-_56757329 0.165 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr16_-_66864806 0.165 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1






NEDD8 activating enzyme E1 subunit 1






chr12_+_110338063 0.165 ENST00000405876.4
TCHP
trichoplein, keratin filament binding
chr8_+_132952112 0.165 ENST00000520362.1
ENST00000519656.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr2_-_56274461 0.164 ENST00000446139.1
AC011306.2
AC011306.2
chr14_+_29299437 0.164 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1



CTD-2384A14.1



chrX_+_102024075 0.163 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630



long intergenic non-protein coding RNA 630



chr3_+_57882061 0.162 ENST00000461354.1
ENST00000466255.1
SLMAP

sarcolemma associated protein

chr20_+_43990576 0.161 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr1_-_23504176 0.161 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr1_+_144173162 0.160 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr1_+_145525015 0.160 ENST00000539363.1
ENST00000538811.1
ITGA10

integrin, alpha 10

chr3_-_127541194 0.160 ENST00000453507.2
MGLL
monoglyceride lipase
chr13_+_97928395 0.159 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr2_+_231090433 0.159 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140





SP140 nuclear body protein





chr4_-_153332886 0.159 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr3_-_52713729 0.158 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1







polybromo 1







chr12_-_13248598 0.157 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr4_+_39460659 0.157 ENST00000513731.1
LIAS
lipoic acid synthetase
chr3_+_171561127 0.154 ENST00000334567.5
ENST00000450693.1
TMEM212

transmembrane protein 212

chr1_+_227751231 0.153 ENST00000343776.5
ENST00000608949.1
ENST00000397097.3
ZNF678


zinc finger protein 678


chr10_-_31146615 0.152 ENST00000444692.2
ZNF438
zinc finger protein 438
chr19_+_58193337 0.152 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551


zinc finger protein 551


chr4_+_106631966 0.150 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD


glutathione S-transferase, C-terminal domain containing


chr1_+_114473350 0.149 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr4_-_170924888 0.149 ENST00000502832.1
ENST00000393704.3
MFAP3L

microfibrillar-associated protein 3-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:2000110 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 3.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 2.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 2.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.3 GO:0070487 monocyte aggregation(GO:0070487)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.8 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.2 GO:0021503 neural fold bending(GO:0021503)
0.1 0.3 GO:0018879 biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.0 1.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.9 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267) negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0097114 NMDA glutamate receptor clustering(GO:0097114) retrograde trans-synaptic signaling(GO:0098917)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.3 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.0 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.8 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 3.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.5 2.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 2.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 2.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.6 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.4 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.5 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.2 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 2.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 2.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 1.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation