Motif ID: IRX2

Z-value: 0.657


Transcription factors associated with IRX2:

Gene SymbolEntrez IDGene Name
IRX2 ENSG00000170561.8 IRX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRX2hg19_v2_chr5_-_2751762_2751784-0.422.6e-01Click!


Activity profile for motif IRX2.

activity profile for motif IRX2


Sorted Z-values histogram for motif IRX2

Sorted Z-values for motif IRX2



Network of associatons between targets according to the STRING database.



First level regulatory network of IRX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_36013368 0.694 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
 MB



myoglobin



chr17_-_5322786 0.510 ENST00000225696.4
 NUP88
nucleoporin 88kDa
chr5_-_94417562 0.410 ENST00000505465.1
 MCTP1
multiple C2 domains, transmembrane 1
chr18_-_33702078 0.391 ENST00000586829.1
 SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr4_-_22444733 0.382 ENST00000508133.1
 GPR125
G protein-coupled receptor 125
chr9_+_35792151 0.378 ENST00000342694.2
 NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr5_+_147258266 0.355 ENST00000296694.4
 SCGB3A2
secretoglobin, family 3A, member 2
chr5_-_94417339 0.323 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
 MCTP1


multiple C2 domains, transmembrane 1


chr13_-_24007815 0.293 ENST00000382298.3
 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr5_-_94417186 0.291 ENST00000312216.8
ENST00000512425.1
 MCTP1

multiple C2 domains, transmembrane 1

chr8_+_26240414 0.276 ENST00000380629.2
 BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr16_+_56899114 0.270 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
 SLC12A3



solute carrier family 12 (sodium/chloride transporter), member 3



chr6_+_27925019 0.257 ENST00000244623.1
 OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr5_-_94417314 0.257 ENST00000505208.1
 MCTP1
multiple C2 domains, transmembrane 1
chr2_-_166060552 0.227 ENST00000283254.7
ENST00000453007.1
 SCN3A

sodium channel, voltage-gated, type III, alpha subunit

chr12_+_112856690 0.226 ENST00000392597.1
ENST00000351677.2
 PTPN11

protein tyrosine phosphatase, non-receptor type 11

chrX_-_24045303 0.216 ENST00000328046.8
 KLHL15
kelch-like family member 15
chrX_-_117119243 0.196 ENST00000539496.1
ENST00000469946.1
 KLHL13

kelch-like family member 13

chrX_+_148855726 0.194 ENST00000370416.4
 HSFX1
heat shock transcription factor family, X linked 1
chr14_+_23790655 0.186 ENST00000397276.2
 PABPN1
poly(A) binding protein, nuclear 1
chr4_+_169575875 0.177 ENST00000503457.1
 PALLD
palladin, cytoskeletal associated protein
chrX_-_148676974 0.176 ENST00000524178.1
 HSFX2
heat shock transcription factor family, X linked 2
chr11_+_77532233 0.176 ENST00000525409.1
 AAMDC
adipogenesis associated, Mth938 domain containing
chr19_-_29704448 0.173 ENST00000304863.4
 UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr9_-_23779367 0.169 ENST00000440102.1
 ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr12_-_91572278 0.167 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
 DCN



decorin



chr11_-_33795893 0.167 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
 FBXO3




F-box protein 3




chr12_-_112856623 0.161 ENST00000551291.2
 RPL6
ribosomal protein L6
chr2_+_46844290 0.160 ENST00000238892.3
 CRIPT
cysteine-rich PDZ-binding protein
chr15_-_80263506 0.159 ENST00000335661.6
 BCL2A1
BCL2-related protein A1
chr2_-_166060382 0.157 ENST00000409101.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr11_+_62648336 0.156 ENST00000338663.7
 SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_33037652 0.152 ENST00000311388.3
 DEPDC7
DEP domain containing 7
chr19_-_40336969 0.147 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
 FBL





fibrillarin





chr2_-_166060571 0.145 ENST00000360093.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_-_130597935 0.142 ENST00000447307.1
ENST00000418546.1
 MIR29B1

microRNA 29a

chrX_+_9431324 0.141 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X





transducin (beta)-like 1X-linked





chr1_+_10292308 0.141 ENST00000377081.1
 KIF1B
kinesin family member 1B
chr16_+_58426296 0.138 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
 GINS3


GINS complex subunit 3 (Psf3 homolog)


chrX_+_19373700 0.128 ENST00000379804.1
 PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr14_-_75536182 0.126 ENST00000555463.1
 ACYP1
acylphosphatase 1, erythrocyte (common) type
chr2_+_138721850 0.125 ENST00000329366.4
ENST00000280097.3
 HNMT

histamine N-methyltransferase

chr4_+_22999152 0.119 ENST00000511453.1
 RP11-412P11.1
RP11-412P11.1
chr1_-_190446759 0.119 ENST00000367462.3
 BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr8_+_26240666 0.112 ENST00000523949.1
 BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr5_-_71803177 0.110 ENST00000414109.2
 ZNF366
zinc finger protein 366
chr8_+_30244580 0.109 ENST00000523115.1
ENST00000519647.1
 RBPMS

RNA binding protein with multiple splicing

chr2_-_233877912 0.107 ENST00000264051.3
 NGEF
neuronal guanine nucleotide exchange factor
chr1_+_215747118 0.106 ENST00000448333.1
 KCTD3
potassium channel tetramerization domain containing 3
chr7_+_93652116 0.105 ENST00000415536.1
 AC003092.1
AC003092.1
chr8_-_124665190 0.105 ENST00000325995.7
 KLHL38
kelch-like family member 38
chr1_+_206516200 0.104 ENST00000295713.5
 SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr3_-_58419537 0.102 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
 PDHB



pyruvate dehydrogenase (lipoamide) beta



chr4_+_26165074 0.101 ENST00000512351.1
 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_-_118739835 0.099 ENST00000542113.1
ENST00000304449.5
 NKRF

NFKB repressing factor

chr1_+_110527308 0.099 ENST00000369799.5
 AHCYL1
adenosylhomocysteinase-like 1
chrX_-_138790348 0.098 ENST00000414978.1
ENST00000519895.1
 MCF2

MCF.2 cell line derived transforming sequence

chr16_-_25026641 0.097 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
 ARHGAP17



Rho GTPase activating protein 17



chr13_+_28519343 0.095 ENST00000381026.3
 ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr8_-_124428569 0.091 ENST00000521903.1
 ATAD2
ATPase family, AAA domain containing 2
chr8_+_81397876 0.090 ENST00000430430.1
 ZBTB10
zinc finger and BTB domain containing 10
chr1_-_207095324 0.088 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
 FAIM3


Fas apoptotic inhibitory molecule 3


chr17_+_76037081 0.086 ENST00000588549.1
 TNRC6C
trinucleotide repeat containing 6C
chr10_-_4285923 0.082 ENST00000418372.1
ENST00000608792.1
 LINC00702

long intergenic non-protein coding RNA 702

chr2_+_196313239 0.081 ENST00000413290.1
 AC064834.1
AC064834.1
chr11_-_76381029 0.081 ENST00000407242.2
ENST00000421973.1
 LRRC32

leucine rich repeat containing 32

chr1_-_149783914 0.081 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
 HIST2H2BF


histone cluster 2, H2bf


chr7_-_130598059 0.081 ENST00000432045.2
 MIR29B1
microRNA 29a
chr4_-_71705060 0.077 ENST00000514161.1
 GRSF1
G-rich RNA sequence binding factor 1
chr4_-_71705027 0.076 ENST00000545193.1
 GRSF1
G-rich RNA sequence binding factor 1
chr4_-_14889791 0.076 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
 LINC00504


long intergenic non-protein coding RNA 504


chr6_+_88117683 0.075 ENST00000369562.4
 C6ORF165
UPF0704 protein C6orf165
chr10_-_100027943 0.074 ENST00000260702.3
 LOXL4
lysyl oxidase-like 4
chr8_+_67405794 0.072 ENST00000522977.1
ENST00000480005.1
 C8orf46

chromosome 8 open reading frame 46

chr1_-_156698181 0.071 ENST00000313146.6
 ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr14_+_50999744 0.070 ENST00000441560.2
 ATL1
atlastin GTPase 1
chr15_+_57998923 0.069 ENST00000380557.4
 POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr16_+_69373323 0.068 ENST00000254940.5
 NIP7
NIP7, nucleolar pre-rRNA processing protein
chr13_+_35516390 0.066 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
 NBEA


neurobeachin


chr19_+_13134772 0.065 ENST00000587760.1
ENST00000585575.1
 NFIX

nuclear factor I/X (CCAAT-binding transcription factor)

chr11_-_118305921 0.065 ENST00000532619.1
 RP11-770J1.4
RP11-770J1.4
chr12_+_90313394 0.065 ENST00000549551.1
 RP11-654D12.2
RP11-654D12.2
chr12_+_128399965 0.064 ENST00000540882.1
ENST00000542089.1
 LINC00507

long intergenic non-protein coding RNA 507

chr9_+_12695702 0.063 ENST00000381136.2
 TYRP1
tyrosinase-related protein 1
chr10_-_14596140 0.063 ENST00000496330.1
 FAM107B
family with sequence similarity 107, member B
chr12_+_32655048 0.060 ENST00000427716.2
ENST00000266482.3
 FGD4

FYVE, RhoGEF and PH domain containing 4

chr2_-_70520539 0.060 ENST00000482975.2
ENST00000438261.1
 SNRPG

small nuclear ribonucleoprotein polypeptide G

chr9_-_13175823 0.059 ENST00000545857.1
 MPDZ
multiple PDZ domain protein
chr7_+_16700806 0.059 ENST00000446596.1
ENST00000438834.1
 BZW2

basic leucine zipper and W2 domains 2

chr19_-_55953704 0.057 ENST00000416792.1
 SHISA7
shisa family member 7
chr5_+_158690089 0.057 ENST00000296786.6
 UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr7_-_21985489 0.057 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
 CDCA7L



cell division cycle associated 7-like



chr3_-_11645925 0.054 ENST00000413604.1
 VGLL4
vestigial like 4 (Drosophila)
chr1_+_152691998 0.053 ENST00000368775.2
 C1orf68
chromosome 1 open reading frame 68
chr17_-_60885700 0.052 ENST00000583600.1
 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr16_+_57680043 0.052 ENST00000569154.1
 GPR56
G protein-coupled receptor 56
chr9_+_79792410 0.051 ENST00000357409.5
 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr3_-_81792780 0.049 ENST00000489715.1
 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_-_26127525 0.048 ENST00000313735.6
 NOS2
nitric oxide synthase 2, inducible
chr3_-_194072019 0.048 ENST00000429275.1
ENST00000323830.3
 CPN2

carboxypeptidase N, polypeptide 2

chr7_-_33140498 0.047 ENST00000448915.1
 RP9
retinitis pigmentosa 9 (autosomal dominant)
chr8_+_50081098 0.047 ENST00000518222.1
ENST00000519828.1
 RP11-10H3.1

RP11-10H3.1

chr2_+_27851863 0.046 ENST00000264718.3
ENST00000610189.1
 GPN1

GPN-loop GTPase 1

chr12_+_65996599 0.046 ENST00000539116.1
ENST00000541391.1
 RP11-221N13.3

RP11-221N13.3

chr22_+_45714672 0.046 ENST00000424557.1
 FAM118A
family with sequence similarity 118, member A
chr10_+_70320413 0.046 ENST00000373644.4
 TET1
tet methylcytosine dioxygenase 1
chr2_-_46844242 0.045 ENST00000281382.6
 PIGF
phosphatidylinositol glycan anchor biosynthesis, class F
chr14_-_50999190 0.044 ENST00000557390.1
 MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_83821676 0.044 ENST00000355196.2
ENST00000507676.1
ENST00000506495.1
ENST00000507051.1
 SEC31A



SEC31 homolog A (S. cerevisiae)



chr12_+_128399917 0.044 ENST00000544645.1
 LINC00507
long intergenic non-protein coding RNA 507
chr1_+_204839959 0.044 ENST00000404076.1
 NFASC
neurofascin
chr1_+_206317450 0.043 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
 CTSE


cathepsin E


chr17_-_60885659 0.043 ENST00000311269.5
 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr10_+_46997926 0.043 ENST00000374314.4
 GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr16_+_58537737 0.041 ENST00000561738.1
 NDRG4
NDRG family member 4
chr14_-_65289812 0.040 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
 SPTB


spectrin, beta, erythrocytic


chr8_+_81397846 0.040 ENST00000379091.4
 ZBTB10
zinc finger and BTB domain containing 10
chr1_+_16083154 0.040 ENST00000375771.1
 FBLIM1
filamin binding LIM protein 1
chr12_-_91505608 0.039 ENST00000266718.4
 LUM
lumican
chr10_+_77056181 0.039 ENST00000526759.1
ENST00000533822.1
 ZNF503-AS1

ZNF503 antisense RNA 1

chr2_-_46844159 0.039 ENST00000474980.1
ENST00000306465.4
 PIGF

phosphatidylinositol glycan anchor biosynthesis, class F

chr4_+_48807155 0.038 ENST00000504654.1
 OCIAD1
OCIA domain containing 1
chr3_-_167371740 0.038 ENST00000466760.1
ENST00000479765.1
 WDR49

WD repeat domain 49

chr12_-_102513843 0.037 ENST00000551744.2
ENST00000552283.1
 NUP37

nucleoporin 37kDa

chr2_+_113479063 0.036 ENST00000327581.4
 NT5DC4
5'-nucleotidase domain containing 4
chr6_+_30908747 0.035 ENST00000462446.1
ENST00000304311.2
 DPCR1

diffuse panbronchiolitis critical region 1

chr4_+_88896819 0.034 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
 SPP1



secreted phosphoprotein 1



chr7_+_99686577 0.032 ENST00000303904.3
ENST00000419210.1
ENST00000418625.1
 COPS6


COP9 signalosome subunit 6


chr20_+_56136136 0.032 ENST00000319441.4
ENST00000543666.1
 PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

chr10_-_14574705 0.032 ENST00000489100.1
 FAM107B
family with sequence similarity 107, member B
chr12_+_80730292 0.031 ENST00000298820.3
 OTOGL
otogelin-like
chr7_+_80275953 0.031 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
 CD36


CD36 molecule (thrombospondin receptor)


chr19_-_51334769 0.030 ENST00000596931.1
ENST00000416184.1
ENST00000301421.2
ENST00000598239.1
 KLK15



kallikrein-related peptidase 15



chr5_-_150138246 0.029 ENST00000518015.1
 DCTN4
dynactin 4 (p62)
chr13_-_22033392 0.029 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
 ZDHHC20





zinc finger, DHHC-type containing 20





chr7_-_123673471 0.029 ENST00000455783.1
 TMEM229A
transmembrane protein 229A
chr8_+_67104323 0.028 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
 LINC00967


long intergenic non-protein coding RNA 967


chr19_-_38720354 0.028 ENST00000416611.1
 DPF1
D4, zinc and double PHD fingers family 1
chr6_+_24775153 0.027 ENST00000356509.3
ENST00000230056.3
 GMNN

geminin, DNA replication inhibitor

chr6_-_160209471 0.027 ENST00000539948.1
 TCP1
t-complex 1
chr9_-_35812140 0.026 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
 SPAG8


sperm associated antigen 8


chr5_+_138210919 0.025 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
 CTNNA1











catenin (cadherin-associated protein), alpha 1, 102kDa











chr1_-_151148492 0.025 ENST00000295314.4
 TMOD4
tropomodulin 4 (muscle)
chr7_-_150020578 0.025 ENST00000478393.1
 ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chrX_-_100129320 0.025 ENST00000372966.3
 NOX1
NADPH oxidase 1
chr10_-_61122625 0.023 ENST00000468840.2
 FAM13C
family with sequence similarity 13, member C
chr5_-_150138061 0.022 ENST00000521533.1
ENST00000424236.1
 DCTN4

dynactin 4 (p62)

chr1_+_29138654 0.022 ENST00000234961.2
 OPRD1
opioid receptor, delta 1
chr3_-_122102065 0.021 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
 CCDC58


coiled-coil domain containing 58


chr1_+_206317591 0.021 ENST00000432969.2
 CTSE
cathepsin E
chr4_+_114214125 0.021 ENST00000509550.1
 ANK2
ankyrin 2, neuronal
chr19_-_38720294 0.020 ENST00000412732.1
ENST00000456296.1
 DPF1

D4, zinc and double PHD fingers family 1

chr17_-_60885645 0.020 ENST00000544856.2
 MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_+_67673297 0.019 ENST00000425614.1
ENST00000395227.1
 IL23R

interleukin 23 receptor

chr20_-_35329063 0.018 ENST00000422536.1
 NDRG3
NDRG family member 3
chr10_+_90660832 0.018 ENST00000371924.1
 STAMBPL1
STAM binding protein-like 1
chrX_+_107020963 0.018 ENST00000509000.2
 NCBP2L
nuclear cap binding protein subunit 2-like
chr4_+_159131630 0.018 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
 TMEM144



transmembrane protein 144



chr16_+_21244986 0.017 ENST00000311620.5
 ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr2_+_234637754 0.017 ENST00000609767.1
ENST00000482026.1
 UGT1A1
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A3
chr3_-_127441406 0.016 ENST00000487473.1
ENST00000484451.1
 MGLL

monoglyceride lipase

chr4_-_80247162 0.016 ENST00000286794.4
 NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr6_-_53013620 0.016 ENST00000259803.7
 GCM1
glial cells missing homolog 1 (Drosophila)
chr3_-_126327398 0.015 ENST00000383572.2
 TXNRD3NB
thioredoxin reductase 3 neighbor
chr9_-_73736511 0.015 ENST00000377110.3
ENST00000377111.2
 TRPM3

transient receptor potential cation channel, subfamily M, member 3

chr1_-_173793458 0.015 ENST00000356198.2
 CENPL
centromere protein L
chr7_-_14880892 0.014 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
 DGKB


diacylglycerol kinase, beta 90kDa


chr20_+_43835638 0.014 ENST00000372781.3
ENST00000244069.6
 SEMG1

semenogelin I

chr2_+_159651821 0.014 ENST00000309950.3
ENST00000409042.1
 DAPL1

death associated protein-like 1

chr5_+_156696362 0.014 ENST00000377576.3
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_+_244227632 0.013 ENST00000598000.1
 AL590483.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr10_+_1095416 0.013 ENST00000358220.1
 WDR37
WD repeat domain 37
chr10_-_14614311 0.013 ENST00000479731.1
ENST00000468492.1
 FAM107B

family with sequence similarity 107, member B

chr5_-_138211051 0.012 ENST00000518785.1
 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr1_+_17516275 0.011 ENST00000412427.1
 RP11-380J14.1
RP11-380J14.1
chr8_-_11996586 0.010 ENST00000333796.3
 USP17L2
ubiquitin specific peptidase 17-like family member 2
chr3_+_46616017 0.010 ENST00000542931.1
 TDGF1
teratocarcinoma-derived growth factor 1
chr14_+_101295638 0.010 ENST00000523671.2
 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_59824127 0.010 ENST00000278865.3
 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_109605663 0.009 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
 EDAR


ectodysplasin A receptor


chr11_-_62477313 0.009 ENST00000464544.1
ENST00000530009.1
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr11_+_111126707 0.009 ENST00000280325.4
 C11orf53
chromosome 11 open reading frame 53
chr3_+_183815318 0.009 ENST00000425359.2
 HTR3E
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
chr1_-_151148442 0.008 ENST00000441701.1
ENST00000416280.2
 TMOD4

tropomodulin 4 (muscle)

chr5_+_161277603 0.007 ENST00000519621.1
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_-_119077695 0.007 ENST00000371410.3
 NKAP
NFKB activating protein
chr3_+_31574189 0.006 ENST00000295770.2
 STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
chr14_+_32964258 0.005 ENST00000556638.1
 AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_34957477 0.005 ENST00000544237.1
 KIAA1045
KIAA1045
chr11_+_98891797 0.004 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
 CNTN5


contactin 5


chr3_+_14061155 0.004 ENST00000532924.1
 TPRXL
tetra-peptide repeat homeobox-like
chr16_+_81272287 0.004 ENST00000425577.2
ENST00000564552.1
 BCMO1

beta-carotene 15,15'-monooxygenase 1

chr3_+_130162328 0.004 ENST00000512482.1
 COL6A5
collagen, type VI, alpha 5
chr7_+_95115210 0.003 ENST00000428113.1
ENST00000325885.5
 ASB4

ankyrin repeat and SOCS box containing 4

chr12_-_16758059 0.003 ENST00000261169.6
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_105332084 0.003 ENST00000472195.1
 ATXN7L1
ataxin 7-like 1
chr17_+_44590076 0.003 ENST00000333412.3
 LRRC37A2
leucine rich repeat containing 37, member A2
chr3_+_184534994 0.003 ENST00000441141.1
ENST00000445089.1
 VPS8

vacuolar protein sorting 8 homolog (S. cerevisiae)

chr9_-_47314222 0.003 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
 AL953854.2


AL953854.2


chr20_-_60294804 0.003 ENST00000317652.1
 RP11-429E11.3
Uncharacterized protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters