Motif ID: INSM1

Z-value: 1.110


Transcription factors associated with INSM1:

Gene SymbolEntrez IDGene Name
INSM1 ENSG00000173404.3 INSM1



Activity profile for motif INSM1.

activity profile for motif INSM1


Sorted Z-values histogram for motif INSM1

Sorted Z-values for motif INSM1



Network of associatons between targets according to the STRING database.



First level regulatory network of INSM1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_89182178 4.702 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr10_+_91061712 4.600 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr15_+_89181974 4.365 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 4.136 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_150466692 1.444 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1


TNFAIP3 interacting protein 1


chr2_-_72374948 1.371 ENST00000546307.1
ENST00000474509.1
CYP26B1

cytochrome P450, family 26, subfamily B, polypeptide 1

chr3_+_50192457 1.344 ENST00000414301.1
ENST00000450338.1
SEMA3F

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

chr3_+_50192537 1.341 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_-_72375167 1.308 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr9_-_123691439 1.300 ENST00000540010.1
TRAF1
TNF receptor-associated factor 1
chr3_+_50192499 1.280 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_-_150467221 1.264 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr1_+_160370344 0.876 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr20_+_48807351 0.864 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_50192833 0.776 ENST00000426511.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_-_27434756 0.669 ENST00000426119.1
ENST00000412471.1
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr2_-_27434611 0.647 ENST00000408041.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_+_14142535 0.639 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr17_+_46184911 0.613 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11




sorting nexin 11




chr2_-_27434635 0.600 ENST00000401463.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr2_-_27435125 0.591 ENST00000414408.1
ENST00000310574.3
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr1_+_156863470 0.585 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1


platelet endothelial aggregation receptor 1


chr12_+_53645870 0.561 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr17_+_46185111 0.543 ENST00000582104.1
ENST00000584335.1
SNX11

sorting nexin 11

chr14_+_65879668 0.526 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
FUT8



fucosyltransferase 8 (alpha (1,6) fucosyltransferase)



chr2_-_153573887 0.522 ENST00000493468.2
ENST00000545856.1
PRPF40A

PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)

chr2_-_153573965 0.518 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_-_65429891 0.518 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr20_-_30310797 0.502 ENST00000422920.1
BCL2L1
BCL2-like 1
chr19_+_45394477 0.498 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
TOMM40




translocase of outer mitochondrial membrane 40 homolog (yeast)




chr6_+_155054459 0.489 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SCAF8


SR-related CTD-associated factor 8


chr14_-_62162541 0.463 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr11_-_65430251 0.457 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA






v-rel avian reticuloendotheliosis viral oncogene homolog A






chr9_-_140115775 0.451 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr9_+_115983808 0.446 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr17_-_7297833 0.444 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr13_-_31736132 0.440 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr11_-_65430554 0.436 ENST00000308639.9
ENST00000406246.3
RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

chr13_-_31736027 0.429 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1


heat shock 105kDa/110kDa protein 1


chr11_+_66610883 0.418 ENST00000309657.3
ENST00000524506.1
RCE1

Ras converting CAAX endopeptidase 1

chr4_-_143767428 0.410 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B


inositol polyphosphate-4-phosphatase, type II, 105kDa


chr8_-_67525524 0.379 ENST00000517885.1
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chrX_+_153059608 0.360 ENST00000370087.1
SSR4
signal sequence receptor, delta
chr16_-_19896220 0.359 ENST00000562469.1
ENST00000300571.2
GPRC5B

G protein-coupled receptor, family C, group 5, member B

chr11_-_57092381 0.343 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr14_+_65879437 0.343 ENST00000394585.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr11_-_64014379 0.343 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_7297519 0.342 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chrX_+_153060090 0.333 ENST00000370086.3
ENST00000370085.3
SSR4

signal sequence receptor, delta

chr3_-_39195037 0.330 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr2_-_73511407 0.320 ENST00000520530.2
FBXO41
F-box protein 41
chr22_+_45064593 0.313 ENST00000432186.1
PRR5
proline rich 5 (renal)
chr19_+_50887585 0.311 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr14_+_102027688 0.308 ENST00000510508.4
ENST00000359323.3
DIO3

deiodinase, iodothyronine, type III

chr2_-_73511559 0.304 ENST00000521871.1
FBXO41
F-box protein 41
chr21_-_46238034 0.299 ENST00000332859.6
SUMO3
small ubiquitin-like modifier 3
chr4_+_56815102 0.294 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr9_+_35538616 0.294 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr21_-_46237959 0.292 ENST00000397898.3
ENST00000411651.2
SUMO3

small ubiquitin-like modifier 3

chr15_+_90118685 0.292 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr19_-_55881741 0.286 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
IL11


interleukin 11


chr8_-_101571933 0.280 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr8_-_67525473 0.265 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr1_-_39325431 0.264 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr11_+_58346584 0.261 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr15_+_90118723 0.256 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr17_-_47755338 0.253 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP



speckle-type POZ protein



chr1_-_1051736 0.253 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
C1orf159




chromosome 1 open reading frame 159




chr2_+_232575168 0.252 ENST00000440384.1
PTMA
prothymosin, alpha
chr2_-_74667612 0.252 ENST00000305557.5
ENST00000233330.6
RTKN

rhotekin

chr2_-_27603582 0.246 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr1_+_10490779 0.238 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr12_-_72057571 0.234 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr1_-_1051455 0.233 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
C1orf159



chromosome 1 open reading frame 159



chr15_-_65426174 0.231 ENST00000204549.4
PDCD7
programmed cell death 7
chr17_-_27277615 0.229 ENST00000583747.1
ENST00000584236.1
PHF12

PHD finger protein 12

chr19_-_48894104 0.227 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr3_-_69062790 0.225 ENST00000540955.1
ENST00000456376.1
EOGT

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

chr20_+_35202909 0.224 ENST00000558028.1
ENST00000560025.1
ENST00000558530.1
TGIF2

TGIF2-C20orf24
TGFB-induced factor homeobox 2

TGIF2-C20orf24 readthrough
chr12_+_113860160 0.224 ENST00000553248.1
ENST00000345635.4
ENST00000547802.1
SDSL


serine dehydratase-like


chrX_+_49020121 0.222 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
MAGIX


MAGI family member, X-linked


chr12_+_113860042 0.221 ENST00000403593.4
SDSL
serine dehydratase-like
chr6_-_17706618 0.217 ENST00000262077.2
ENST00000537253.1
NUP153

nucleoporin 153kDa

chrX_-_41782249 0.211 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr4_-_83931862 0.204 ENST00000506560.1
ENST00000442461.2
ENST00000446851.2
ENST00000340417.3
LIN54



lin-54 homolog (C. elegans)



chr1_+_145525015 0.203 ENST00000539363.1
ENST00000538811.1
ITGA10

integrin, alpha 10

chr10_+_35415851 0.203 ENST00000374726.3
CREM
cAMP responsive element modulator
chr2_+_32582086 0.201 ENST00000421745.2
BIRC6
baculoviral IAP repeat containing 6
chr7_-_128695147 0.197 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
TNPO3


transportin 3


chr7_-_105752971 0.196 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr10_+_88516396 0.196 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr1_+_54411715 0.196 ENST00000371370.3
ENST00000371368.1
LRRC42

leucine rich repeat containing 42

chr15_+_76352178 0.193 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr9_-_98269481 0.191 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1


patched 1


chr3_-_15901278 0.190 ENST00000399451.2
ANKRD28
ankyrin repeat domain 28
chr6_+_32938665 0.190 ENST00000374831.4
ENST00000395289.2
BRD2

bromodomain containing 2

chr1_-_6557156 0.186 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_+_10490441 0.185 ENST00000309048.3
ENST00000470413.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr6_+_32938692 0.185 ENST00000443797.2
BRD2
bromodomain containing 2
chr1_+_145524891 0.181 ENST00000369304.3
ITGA10
integrin, alpha 10
chr1_+_10490127 0.179 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1

APITD1-CORT
apoptosis-inducing, TAF9-like domain 1

APITD1-CORT readthrough
chr1_-_36851489 0.179 ENST00000373130.3
ENST00000373132.3
STK40

serine/threonine kinase 40

chr21_-_46707793 0.179 ENST00000331343.7
ENST00000349485.5
POFUT2

protein O-fucosyltransferase 2

chr11_+_120110863 0.178 ENST00000543440.2
POU2F3
POU class 2 homeobox 3
chr7_-_128694927 0.177 ENST00000471166.1
ENST00000265388.5
TNPO3

transportin 3

chr15_-_75748143 0.174 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A




SIN3 transcription regulator family member A




chr6_-_9933500 0.173 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr17_-_47755436 0.166 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP






speckle-type POZ protein






chr7_+_94536898 0.158 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr5_-_141030943 0.157 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1


FCH and double SH3 domains 1


chr14_+_73563735 0.155 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr9_-_98269699 0.154 ENST00000429896.2
PTCH1
patched 1
chr3_+_195413160 0.152 ENST00000599448.1
LINC00969
long intergenic non-protein coding RNA 969
chr1_-_154943212 0.150 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr17_+_45608430 0.148 ENST00000322157.4
NPEPPS
aminopeptidase puromycin sensitive
chr15_-_52263937 0.148 ENST00000315141.5
ENST00000299601.5
LEO1

Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

chr6_-_41863098 0.148 ENST00000373006.1
USP49
ubiquitin specific peptidase 49
chr17_-_36413133 0.147 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
RP11-1407O15.2


TBC1 domain family member 3


chr1_-_236445251 0.145 ENST00000354619.5
ENST00000327333.8
ERO1LB

ERO1-like beta (S. cerevisiae)

chr7_-_105752651 0.144 ENST00000470347.1
ENST00000455385.2
SYPL1

synaptophysin-like 1

chr12_+_58148842 0.143 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr17_-_4890919 0.143 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2



calmodulin binding transcription activator 2



chr1_-_36851475 0.141 ENST00000373129.3
STK40
serine/threonine kinase 40
chr4_-_147443043 0.141 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7




solute carrier family 10, member 7




chr18_+_46065483 0.140 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr12_+_53773944 0.138 ENST00000551969.1
ENST00000327443.4
SP1

Sp1 transcription factor

chr1_-_235116495 0.135 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr11_-_118972575 0.134 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr15_+_45722727 0.134 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48


chromosome 15 open reading frame 48


chr7_-_84816122 0.133 ENST00000444867.1
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr4_+_56814968 0.130 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr2_+_152266604 0.130 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr8_+_145065705 0.129 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr1_+_228395755 0.126 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN




obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF




chr20_-_45981138 0.126 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr14_-_104313824 0.124 ENST00000553739.1
ENST00000202556.9
PPP1R13B

protein phosphatase 1, regulatory subunit 13B

chr17_+_45608614 0.122 ENST00000544660.1
NPEPPS
aminopeptidase puromycin sensitive
chr12_-_76953513 0.122 ENST00000547540.1
OSBPL8
oxysterol binding protein-like 8
chr22_+_20105259 0.117 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RANBP1



RAN binding protein 1



chr15_-_70388943 0.110 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chr1_-_85666688 0.110 ENST00000341460.5
SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr6_+_56819895 0.107 ENST00000370748.3
BEND6
BEN domain containing 6
chr17_+_34058639 0.107 ENST00000268864.3
RASL10B
RAS-like, family 10, member B
chr17_-_4890649 0.107 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr22_+_20105012 0.106 ENST00000331821.3
ENST00000411892.1
RANBP1

RAN binding protein 1

chr1_-_154531095 0.105 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr17_+_58755184 0.105 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr5_+_178986693 0.105 ENST00000437570.2
ENST00000393438.2
RUFY1

RUN and FYVE domain containing 1

chr22_-_36903069 0.104 ENST00000216187.6
ENST00000423980.1
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr22_-_36903101 0.098 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr19_-_19626351 0.098 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr1_-_85725316 0.098 ENST00000344356.5
ENST00000471115.1
C1orf52

chromosome 1 open reading frame 52

chr9_-_127533519 0.095 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1


nuclear receptor subfamily 6, group A, member 1


chr3_+_179040767 0.094 ENST00000496856.1
ENST00000491818.1
ZNF639

zinc finger protein 639

chr17_+_42081914 0.093 ENST00000293404.3
ENST00000589767.1
NAGS

N-acetylglutamate synthase

chr14_+_62162258 0.091 ENST00000337138.4
ENST00000394997.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr18_+_34409069 0.091 ENST00000543923.1
ENST00000280020.5
ENST00000435985.2
ENST00000592521.1
ENST00000587139.1
KIAA1328




KIAA1328




chr22_+_20104947 0.091 ENST00000402752.1
RANBP1
RAN binding protein 1
chr18_+_46065570 0.089 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr8_-_124286495 0.089 ENST00000297857.2
ZHX1
zinc fingers and homeoboxes 1
chr12_-_76953453 0.086 ENST00000549570.1
OSBPL8
oxysterol binding protein-like 8
chr3_-_69062764 0.084 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr9_+_131452239 0.082 ENST00000372688.4
ENST00000372686.5
SET

SET nuclear oncogene

chr4_+_26322409 0.081 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr3_+_185304059 0.081 ENST00000427465.2
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_-_69062742 0.079 ENST00000424374.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_-_159313214 0.078 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148


coiled-coil domain containing 148


chr12_-_118810688 0.072 ENST00000542532.1
ENST00000392533.3
TAOK3

TAO kinase 3

chr7_+_100318423 0.072 ENST00000252723.2
EPO
erythropoietin
chr2_+_152266392 0.070 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1






RAP1 interacting factor homolog (yeast)






chrX_-_153059811 0.069 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
IDH3G


isocitrate dehydrogenase 3 (NAD+) gamma


chr17_+_7211280 0.068 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A


eukaryotic translation initiation factor 5A


chrX_+_118892545 0.068 ENST00000343905.3
SOWAHD
sosondowah ankyrin repeat domain family member D
chr22_-_20104700 0.067 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A




tRNA methyltransferase 2 homolog A (S. cerevisiae)




chr19_+_54695098 0.066 ENST00000396388.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr10_+_48359344 0.065 ENST00000412534.1
ENST00000444585.1
ZNF488

zinc finger protein 488

chr12_-_76953573 0.064 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
OSBPL8




oxysterol binding protein-like 8




chr19_-_14201776 0.061 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr9_-_37034028 0.060 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr6_-_146285221 0.059 ENST00000367503.3
ENST00000438092.2
ENST00000275233.7
SHPRH


SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase


chr2_+_208394794 0.059 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1


cAMP responsive element binding protein 1


chr17_+_37793318 0.055 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr21_+_46825032 0.052 ENST00000400337.2
COL18A1
collagen, type XVIII, alpha 1
chrX_-_153059958 0.052 ENST00000370092.3
ENST00000217901.5
IDH3G

isocitrate dehydrogenase 3 (NAD+) gamma

chr22_+_37447771 0.051 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17


potassium channel tetramerization domain containing 17


chr17_+_37793378 0.049 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
STARD3





StAR-related lipid transfer (START) domain containing 3





chr8_-_120685608 0.048 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr8_-_57123815 0.046 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr12_-_52887034 0.044 ENST00000330722.6
KRT6A
keratin 6A
chr7_-_132262060 0.043 ENST00000359827.3
PLXNA4
plexin A4
chr11_-_66445219 0.043 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B




RNA binding motif protein 4B




chr19_+_10197463 0.042 ENST00000590378.1
ENST00000397881.3
C19orf66

chromosome 19 open reading frame 66

chrX_+_37430822 0.042 ENST00000378621.3
ENST00000378619.3
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr12_+_53774423 0.041 ENST00000426431.2
SP1
Sp1 transcription factor
chr19_+_35629702 0.041 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr3_+_14989186 0.039 ENST00000435454.1
ENST00000323373.6
NR2C2

nuclear receptor subfamily 2, group C, member 2

chr20_+_32077880 0.038 ENST00000342704.6
ENST00000375279.2
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr6_-_146285455 0.037 ENST00000367505.2
SHPRH
SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
chr12_+_7342441 0.037 ENST00000412720.2
ENST00000396637.3
PEX5

peroxisomal biogenesis factor 5

chr12_-_50101003 0.037 ENST00000550488.1
FMNL3
formin-like 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.9 2.7 GO:2001037 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.5 2.7 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.5 1.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.4 2.5 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.4 4.7 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.3 4.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 0.9 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.9 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 0.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.9 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.4 GO:0015677 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0048372 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.0 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.6 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0061030 elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101) negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.0 GO:0021644 vagus nerve morphogenesis(GO:0021644) chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.0 1.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 1.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.6 GO:0070911 global genome nucleotide-excision repair(GO:0070911)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.1 12.3 GO:0015030 Cajal body(GO:0015030)
0.1 0.7 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 2.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 2.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 4.7 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.9 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 1.8 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 1.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 2.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 4.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.4 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 2.7 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones