Motif ID: HSFY2

Z-value: 0.520


Transcription factors associated with HSFY2:

Gene SymbolEntrez IDGene Name
HSFY2 ENSG00000169953.11 HSFY2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_20935621-0.068.8e-01Click!


Activity profile for motif HSFY2.

activity profile for motif HSFY2


Sorted Z-values histogram for motif HSFY2

Sorted Z-values for motif HSFY2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSFY2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_165555200 0.537 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr12_+_86268065 0.503 ENST00000551529.1
ENST00000256010.6
NTS

neurotensin

chr6_-_64029879 0.438 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr19_+_3721719 0.433 ENST00000589378.1
ENST00000382008.3
TJP3

tight junction protein 3

chr17_-_7145475 0.395 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP


GABA(A) receptor-associated protein


chr7_-_138363824 0.376 ENST00000419765.3
SVOPL
SVOP-like
chr2_+_196521458 0.350 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_196521845 0.302 ENST00000359634.5
ENST00000412905.1
SLC39A10

solute carrier family 39 (zinc transporter), member 10

chr2_+_196521903 0.272 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chrX_+_57618269 0.264 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr2_+_196522032 0.262 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr11_-_66725837 0.239 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr1_+_111991474 0.233 ENST00000369722.3
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr2_+_36923830 0.215 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr2_+_36923933 0.212 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr3_-_52569023 0.211 ENST00000307076.4
NT5DC2
5'-nucleotidase domain containing 2
chr2_-_183106641 0.205 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr11_+_112047087 0.200 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2


beta-carotene oxygenase 2


chr15_+_41624892 0.193 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
NUSAP1






nucleolar and spindle associated protein 1






chr19_-_1876156 0.192 ENST00000565797.1
CTB-31O20.2
CTB-31O20.2
chr13_-_41706864 0.189 ENST00000379485.1
ENST00000499385.2
KBTBD6

kelch repeat and BTB (POZ) domain containing 6

chr12_-_10562356 0.189 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr18_-_48351743 0.184 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO


maestro


chr14_-_70883708 0.183 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr19_-_46142637 0.183 ENST00000590043.1
ENST00000589876.1
EML2

echinoderm microtubule associated protein like 2

chr10_+_35415978 0.180 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr14_-_23762777 0.178 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr12_-_9360966 0.178 ENST00000261336.2
PZP
pregnancy-zone protein
chr9_+_131684027 0.176 ENST00000426694.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr6_-_13290684 0.175 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr19_-_46142680 0.174 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr17_-_8198636 0.171 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35


solute carrier family 25, member 35


chr3_+_111697843 0.167 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10


abhydrolase domain containing 10


chr16_+_9056563 0.166 ENST00000564485.1
RP11-77H9.8
RP11-77H9.8
chrX_-_15511438 0.165 ENST00000380420.5
PIR
pirin (iron-binding nuclear protein)
chr7_-_32338917 0.159 ENST00000396193.1
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_26232522 0.159 ENST00000399728.1
STMN1
stathmin 1
chr22_-_31688431 0.159 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr13_+_27825706 0.157 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr17_-_7590745 0.156 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53







tumor protein p53







chrX_-_99987088 0.156 ENST00000372981.1
ENST00000263033.5
SYTL4

synaptotagmin-like 4

chr12_-_91572278 0.156 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN



decorin



chr3_+_100428188 0.156 ENST00000418917.2
ENST00000490574.1
TFG

TRK-fused gene

chr11_-_83393429 0.155 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr10_+_35415719 0.154 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr10_+_35416090 0.154 ENST00000354759.3
CREM
cAMP responsive element modulator
chr5_+_32788945 0.154 ENST00000326958.1
AC026703.1
AC026703.1
chr2_+_36923901 0.153 ENST00000457137.2
VIT
vitrin
chr11_+_111957497 0.153 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD





succinate dehydrogenase complex, subunit D, integral membrane protein





chr12_+_12510045 0.150 ENST00000314565.4
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr2_-_102003987 0.150 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr8_+_81397876 0.149 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr5_-_81574160 0.147 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23




ribosomal protein S23




chr12_+_12509990 0.147 ENST00000542728.1
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr3_+_100428316 0.144 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG


TRK-fused gene


chr14_+_39944025 0.143 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr10_+_35416223 0.143 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM





cAMP responsive element modulator





chr18_-_10791648 0.139 ENST00000583325.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr21_-_40720995 0.136 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr2_-_1748214 0.136 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr6_-_73935163 0.135 ENST00000370388.3
KHDC1L
KH homology domain containing 1-like
chr5_+_271733 0.133 ENST00000264933.4
PDCD6
programmed cell death 6
chr3_-_171489085 0.130 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr7_-_38305279 0.129 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr5_-_122372354 0.129 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr4_-_90756769 0.129 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr3_-_69249863 0.129 ENST00000478263.1
ENST00000462512.1
FRMD4B

FERM domain containing 4B

chr15_-_50411412 0.126 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr11_-_61100830 0.124 ENST00000301764.7
DDB1
damage-specific DNA binding protein 1, 127kDa
chr4_-_90757364 0.124 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr10_+_70587279 0.124 ENST00000298596.6
ENST00000399169.4
ENST00000399165.4
ENST00000399162.2
STOX1



storkhead box 1



chr17_-_73043046 0.124 ENST00000301587.4
ENST00000344546.4
ATP5H

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d

chr9_+_131684562 0.123 ENST00000421063.2
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr5_+_147443534 0.122 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5



serine peptidase inhibitor, Kazal type 5



chr17_+_30469579 0.122 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
RHOT1


ras homolog family member T1


chr13_-_114567034 0.120 ENST00000327773.6
ENST00000357389.3
GAS6

growth arrest-specific 6

chr3_+_3168600 0.120 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
TRNT1



tRNA nucleotidyl transferase, CCA-adding, 1



chr4_+_184826418 0.119 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr17_+_76311791 0.119 ENST00000586321.1
AC061992.2
AC061992.2
chr6_+_122720681 0.118 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr11_+_5646213 0.118 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr8_-_74206133 0.115 ENST00000352983.2
RPL7
ribosomal protein L7
chr3_-_52008016 0.114 ENST00000461108.1
ENST00000395008.2
ENST00000525795.1
ENST00000361143.5
ENST00000489595.2
ABHD14B



RP11-155D18.14
abhydrolase domain containing 14B



Poly(rC)-binding protein 4
chr8_-_74206673 0.114 ENST00000396465.1
RPL7
ribosomal protein L7
chr11_-_62439012 0.114 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
C11orf48




chromosome 11 open reading frame 48




chr11_-_61100500 0.113 ENST00000450997.2
ENST00000543658.1
ENST00000542337.1
DDB1


damage-specific DNA binding protein 1, 127kDa


chr12_+_96337061 0.113 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr4_+_186317133 0.112 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr13_-_45915221 0.110 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1




tumor protein, translationally-controlled 1




chr13_+_37581115 0.110 ENST00000481013.1
EXOSC8
exosome component 8
chr1_+_145726886 0.109 ENST00000443667.1
PDZK1
PDZ domain containing 1
chr6_-_79944336 0.109 ENST00000344726.5
ENST00000275036.7
HMGN3

high mobility group nucleosomal binding domain 3

chr12_-_54691668 0.109 ENST00000553198.1
NFE2
nuclear factor, erythroid 2
chr20_+_10199468 0.108 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chrX_+_155110956 0.107 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7


vesicle-associated membrane protein 7


chr1_-_89458415 0.107 ENST00000370491.3
ENST00000321792.5
CCBL2
RBMXL1
cysteine conjugate-beta lyase 2
RNA binding motif protein, X-linked-like 1
chr12_-_7125770 0.107 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr11_-_77850629 0.106 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
ALG8






ALG8, alpha-1,3-glucosyltransferase






chr1_+_62417957 0.106 ENST00000307297.7
ENST00000543708.1
INADL

InaD-like (Drosophila)

chr12_-_54121212 0.104 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1







calcium binding and coiled-coil domain 1







chr12_-_8088773 0.104 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr21_-_40720974 0.104 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr4_-_100871506 0.103 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr18_-_37380230 0.102 ENST00000591629.1
LINC00669
long intergenic non-protein coding RNA 669
chr14_-_27291313 0.102 ENST00000549330.1
RP11-626P14.1
RP11-626P14.1
chr8_+_38089198 0.101 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2



DDHD domain containing 2



chr2_-_84686552 0.101 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr1_-_89458287 0.101 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr1_+_197170592 0.100 ENST00000535699.1
CRB1
crumbs homolog 1 (Drosophila)
chr3_+_141594966 0.099 ENST00000475483.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr7_-_7679633 0.098 ENST00000401447.1
RPA3
replication protein A3, 14kDa
chr3_+_155838337 0.096 ENST00000490337.1
ENST00000389636.5
KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr12_-_71533055 0.096 ENST00000552128.1
TSPAN8
tetraspanin 8
chr5_+_81601166 0.095 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr22_-_41985865 0.095 ENST00000216259.7
PMM1
phosphomannomutase 1
chr13_-_24471641 0.095 ENST00000382145.1
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr14_-_45603657 0.095 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr11_+_86667117 0.095 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr8_-_97247759 0.093 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB


ubiquinol-cytochrome c reductase binding protein


chr11_-_61124776 0.091 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr3_-_186262166 0.090 ENST00000307944.5
CRYGS
crystallin, gamma S
chr11_+_123986069 0.089 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A





von Willebrand factor A domain containing 5A





chr1_+_234509413 0.089 ENST00000366613.1
ENST00000366612.1
COA6

cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)

chr3_-_111852128 0.088 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr3_-_187455680 0.088 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_+_17337007 0.087 ENST00000215061.4
OCEL1
occludin/ELL domain containing 1
chr3_+_23847394 0.087 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr6_+_150070857 0.087 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_-_83393457 0.087 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr15_-_85259360 0.086 ENST00000559729.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr17_+_1733276 0.086 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr8_-_17579726 0.085 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr19_-_11450249 0.084 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr4_-_169931393 0.084 ENST00000504480.1
ENST00000306193.3
CBR4

carbonyl reductase 4

chr15_-_85259330 0.083 ENST00000560266.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr11_+_93394805 0.083 ENST00000325212.6
ENST00000411936.1
ENST00000344196.4
KIAA1731


KIAA1731


chr15_+_48623600 0.083 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
DUT


deoxyuridine triphosphatase


chr3_+_100428268 0.083 ENST00000240851.4
TFG
TRK-fused gene
chr17_+_68165657 0.083 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_39448180 0.082 ENST00000301821.6
ENST00000458478.1
ENST00000443003.1
RPSA


ribosomal protein SA


chr10_-_25010795 0.082 ENST00000416305.1
ENST00000376410.2
ARHGAP21

Rho GTPase activating protein 21

chr17_-_73975444 0.082 ENST00000293217.5
ENST00000537812.1
ACOX1

acyl-CoA oxidase 1, palmitoyl

chr7_-_95025661 0.081 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr16_-_31214051 0.081 ENST00000350605.4
PYCARD
PYD and CARD domain containing
chr14_+_72064945 0.081 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr7_-_124405681 0.081 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr12_-_54121261 0.081 ENST00000549784.1
ENST00000262059.4
CALCOCO1

calcium binding and coiled-coil domain 1

chr14_+_20923350 0.081 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1











APEX nuclease (multifunctional DNA repair enzyme) 1











chr5_+_154238149 0.081 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
CNOT8






CCR4-NOT transcription complex, subunit 8






chr20_+_33292068 0.080 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr3_-_149093499 0.080 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr17_-_30470154 0.080 ENST00000398832.2
AC090616.2
Uncharacterized protein
chr14_-_31926595 0.079 ENST00000547378.1
RP11-176H8.1
Uncharacterized protein
chr19_-_33182616 0.079 ENST00000592431.1
CTD-2538C1.2
CTD-2538C1.2
chr16_-_18801582 0.079 ENST00000565420.1
RPS15A
ribosomal protein S15a
chr15_-_85259294 0.078 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11A


SEC11 homolog A (S. cerevisiae)


chr19_+_17337027 0.077 ENST00000601529.1
ENST00000600232.1
OCEL1

occludin/ELL domain containing 1

chr20_+_34129770 0.077 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC3






ERGIC and golgi 3






chr15_-_85259384 0.076 ENST00000455959.3
SEC11A
SEC11 homolog A (S. cerevisiae)
chr13_+_21714653 0.076 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr16_-_81040415 0.075 ENST00000564174.1
ENST00000562713.1
ENST00000570195.1
ENST00000565925.1
ENST00000565108.1
ENST00000565650.1
ENST00000486645.1
CMC2






C-x(9)-C motif containing 2






chr14_-_75536182 0.075 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr9_-_33167308 0.074 ENST00000535206.1
ENST00000379731.4
B4GALT1

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

chr16_-_18801643 0.074 ENST00000322989.4
ENST00000563390.1
RPS15A

ribosomal protein S15a

chr12_-_57119300 0.074 ENST00000546917.1
ENST00000454682.1
NACA

nascent polypeptide-associated complex alpha subunit

chr13_+_27825446 0.073 ENST00000311549.6
RPL21
ribosomal protein L21
chr15_-_41624685 0.073 ENST00000560640.1
ENST00000220514.3
OIP5

Opa interacting protein 5

chr5_+_42756903 0.073 ENST00000361970.5
ENST00000388827.4
CCDC152

coiled-coil domain containing 152

chr3_+_101280677 0.072 ENST00000309922.6
ENST00000495642.1
TRMT10C

tRNA methyltransferase 10 homolog C (S. cerevisiae)

chr18_+_39535239 0.072 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr1_+_93297622 0.072 ENST00000315741.5
RPL5
ribosomal protein L5
chr9_+_133971863 0.072 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chr1_+_186798073 0.071 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr2_+_201754050 0.071 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1




NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)




chr5_+_159848854 0.070 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr12_+_117013656 0.069 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr9_+_133971909 0.069 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L



allograft inflammatory factor 1-like



chr17_+_28705921 0.068 ENST00000225719.4
CPD
carboxypeptidase D
chr4_+_130017268 0.068 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33


chromosome 4 open reading frame 33


chr13_-_33112823 0.068 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr7_-_35077653 0.068 ENST00000310974.4
DPY19L1
dpy-19-like 1 (C. elegans)
chr1_+_196788887 0.066 ENST00000367421.3
ENST00000320493.5
ENST00000367424.4
CFHR2
CFHR1

complement factor H-related 2
complement factor H-related 1

chr5_-_70320514 0.065 ENST00000517649.1
NAIP
NLR family, apoptosis inhibitory protein
chr11_-_46113756 0.065 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr15_+_99791716 0.065 ENST00000558172.1
ENST00000561276.1
ENST00000331450.5
LRRC28


leucine rich repeat containing 28


chr13_+_21714711 0.065 ENST00000607003.1
ENST00000492245.1
SAP18

Sin3A-associated protein, 18kDa

chr11_-_62599505 0.064 ENST00000377897.4
ENST00000394690.1
ENST00000541317.1
ENST00000294179.3
STX5



syntaxin 5



chr6_-_26285737 0.064 ENST00000377727.1
ENST00000289352.1
HIST1H4H

histone cluster 1, H4h

chr19_+_50194360 0.064 ENST00000323446.5
ENST00000392518.4
ENST00000598396.1
ENST00000598293.1
ENST00000354199.5
ENST00000405931.2
ENST00000602019.1
CPT1C






carnitine palmitoyltransferase 1C






chr14_+_24701628 0.064 ENST00000355299.4
ENST00000559836.1
GMPR2

guanosine monophosphate reductase 2

chr14_-_70826438 0.063 ENST00000389912.6
COX16
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chrX_-_47004878 0.063 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr4_-_36246060 0.063 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_148804275 0.062 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr6_-_711395 0.062 ENST00000606285.1
RP11-532F6.3
RP11-532F6.3
chr2_-_136633940 0.062 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr15_+_49170083 0.061 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr3_+_122399697 0.061 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr19_-_52674896 0.061 ENST00000322146.8
ENST00000597065.1
ZNF836

zinc finger protein 836

chr9_-_99180597 0.061 ENST00000375256.4
ZNF367
zinc finger protein 367

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 0.2 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.3 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.0 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1903519 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0070685 macropinocytic cup(GO:0070685)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0048037 cofactor binding(GO:0048037)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins