Motif ID: HOXC12_HOXD12

Z-value: 0.820

Transcription factors associated with HOXC12_HOXD12:

Gene SymbolEntrez IDGene Name
HOXC12 ENSG00000123407.3 HOXC12
HOXD12 ENSG00000170178.5 HOXD12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXC12hg19_v2_chr12_+_54348618_54348693-0.722.8e-02Click!
HOXD12hg19_v2_chr2_+_176964458_1769645400.373.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_76957214 1.908 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr5_+_35852797 1.621 ENST00000508941.1
IL7R
interleukin 7 receptor
chr6_+_106988986 1.121 ENST00000457437.1
ENST00000535438.1
AIM1

absent in melanoma 1

chr12_+_104337515 0.971 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_+_113354341 0.838 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chrX_-_15619076 0.692 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr12_-_15114603 0.635 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_-_74964904 0.624 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr12_-_15114492 0.557 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_31681839 0.525 ENST00000461287.1
ENST00000409239.1
XXbac-BPG32J3.20
LY6G6E
Uncharacterized protein
lymphocyte antigen 6 complex, locus G6E (pseudogene)
chr11_+_35160709 0.521 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44











CD44 molecule (Indian blood group)











chr12_+_54384370 0.521 ENST00000504315.1
HOXC6
homeobox C6
chr13_+_49551020 0.519 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr13_-_24895566 0.493 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr1_+_100818009 0.488 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A


cell division cycle 14A


chr8_+_101170563 0.469 ENST00000520508.1
ENST00000388798.2
SPAG1

sperm associated antigen 1

chr15_+_41245160 0.458 ENST00000444189.2
ENST00000446533.3
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr1_+_213224572 0.446 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1



ribosomal protein S6 kinase, 52kDa, polypeptide 1



chr12_-_15114191 0.404 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_-_30311703 0.394 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1



BCL2-like 1



chr19_-_39523165 0.393 ENST00000509137.2
ENST00000292853.4
FBXO27

F-box protein 27

chr4_-_123843597 0.391 ENST00000510735.1
ENST00000304430.5
NUDT6

nudix (nucleoside diphosphate linked moiety X)-type motif 6

chr1_-_146989697 0.391 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr4_-_129491686 0.376 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr1_-_155948890 0.375 ENST00000471589.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_201450591 0.364 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr12_-_15114658 0.363 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_-_134093738 0.353 ENST00000506107.1
AMOTL2
angiomotin like 2
chr11_+_7506584 0.341 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr16_-_66907139 0.340 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr1_+_158975744 0.339 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr7_+_76090993 0.327 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2










deltex homolog 2 (Drosophila)










chr11_-_107328527 0.326 ENST00000282251.5
ENST00000433523.1
CWF19L2

CWF19-like 2, cell cycle control (S. pombe)

chr11_-_72301463 0.323 ENST00000475807.2
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_-_796197 0.315 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr6_+_126221034 0.307 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr19_-_55677999 0.297 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3


dynein, axonemal, assembly factor 3


chr2_+_74056066 0.288 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP





STAM binding protein





chr2_+_55746746 0.281 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
CCDC104



coiled-coil domain containing 104



chr2_+_190541153 0.280 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR



ankyrin and armadillo repeat containing



chr5_-_176433565 0.273 ENST00000428382.2
UIMC1
ubiquitin interaction motif containing 1
chr7_+_138915102 0.271 ENST00000486663.1
UBN2
ubinuclein 2
chr8_-_33370607 0.271 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr12_-_30887948 0.271 ENST00000433722.2
CAPRIN2
caprin family member 2
chr15_+_101459420 0.270 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1



leucine-rich repeat kinase 1



chr15_-_71184724 0.270 ENST00000560604.1
THAP10
THAP domain containing 10
chr6_-_56716686 0.267 ENST00000520645.1
DST
dystonin
chr9_-_4299874 0.264 ENST00000381971.3
ENST00000477901.1
GLIS3

GLIS family zinc finger 3

chr12_+_110940005 0.263 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B



RAD9 homolog B (S. pombe)



chr11_+_110001723 0.259 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr9_+_15553055 0.258 ENST00000380701.3
CCDC171
coiled-coil domain containing 171
chr11_-_119991589 0.257 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr19_+_11200038 0.255 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR





low density lipoprotein receptor





chr17_+_46184911 0.253 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11




sorting nexin 11




chr6_+_30539153 0.251 ENST00000326195.8
ENST00000376545.3
ENST00000396515.4
ENST00000441867.1
ENST00000468958.1
ABCF1




ATP-binding cassette, sub-family F (GCN20), member 1




chr12_-_49523896 0.248 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr7_+_76101379 0.244 ENST00000429179.1
DTX2
deltex homolog 2 (Drosophila)
chr10_+_51549498 0.243 ENST00000358559.2
ENST00000298239.6
MSMB

microseminoprotein, beta-

chr10_+_31608054 0.237 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr1_+_156308403 0.235 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC



TSSK6 activating co-chaperone



chr8_+_77318769 0.234 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr6_+_32812568 0.233 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr14_+_39944025 0.233 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr1_+_199996702 0.230 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr4_-_17513604 0.228 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr21_+_46359907 0.227 ENST00000291634.6
ENST00000397826.3
ENST00000458015.1
FAM207A


family with sequence similarity 207, member A


chr2_-_225811747 0.227 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr22_-_29107919 0.226 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr2_+_74056147 0.224 ENST00000394070.2
ENST00000536064.1
STAMBP

STAM binding protein

chr5_-_175815565 0.222 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16


NOP16 nucleolar protein


chr1_+_100817262 0.221 ENST00000455467.1
CDC14A
cell division cycle 14A
chr1_+_171750776 0.221 ENST00000458517.1
ENST00000362019.3
ENST00000367737.5
ENST00000361735.3
METTL13



methyltransferase like 13



chr16_+_9056563 0.220 ENST00000564485.1
RP11-77H9.8
RP11-77H9.8
chr7_+_28452130 0.220 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr1_+_59775752 0.219 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr11_-_3400330 0.219 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
ZNF195











zinc finger protein 195











chr8_-_63998590 0.218 ENST00000260116.4
TTPA
tocopherol (alpha) transfer protein
chr14_+_73634537 0.217 ENST00000406768.1
PSEN1
presenilin 1
chr6_+_20534672 0.217 ENST00000274695.4
ENST00000378624.4
CDKAL1

CDK5 regulatory subunit associated protein 1-like 1

chr1_+_178694300 0.214 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_-_152146385 0.210 ENST00000414946.1
ENST00000243346.5
NMI

N-myc (and STAT) interactor

chr12_+_67663056 0.209 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr3_+_137906109 0.208 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8



armadillo repeat containing 8



chr12_+_6561190 0.206 ENST00000544021.1
ENST00000266556.7
TAPBPL

TAP binding protein-like

chr12_+_14956506 0.206 ENST00000330828.2
C12orf60
chromosome 12 open reading frame 60
chr7_+_138818490 0.205 ENST00000430935.1
ENST00000495038.1
ENST00000474035.2
ENST00000478836.2
ENST00000464848.1
ENST00000343187.4
TTC26





tetratricopeptide repeat domain 26





chr2_+_131769256 0.200 ENST00000355771.3
ARHGEF4
Rho guanine nucleotide exchange factor (GEF) 4
chr16_+_84875609 0.200 ENST00000563066.1
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr19_+_21265028 0.199 ENST00000291770.7
ZNF714
zinc finger protein 714
chr12_-_66524482 0.198 ENST00000446587.2
ENST00000266604.2
LLPH

LLP homolog, long-term synaptic facilitation (Aplysia)

chr1_+_66820058 0.197 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_-_26199471 0.197 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr7_-_72992663 0.195 ENST00000432538.1
TBL2
transducin (beta)-like 2
chr1_-_247242048 0.195 ENST00000366503.2
ZNF670
zinc finger protein 670
chr7_-_27219849 0.192 ENST00000396344.4
HOXA10
homeobox A10
chr1_+_199996733 0.191 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr4_-_17513702 0.191 ENST00000428702.2
ENST00000508623.1
ENST00000513615.1
QDPR


quinoid dihydropteridine reductase


chr5_+_154135453 0.191 ENST00000517616.1
ENST00000518892.1
LARP1

La ribonucleoprotein domain family, member 1

chr19_-_55677920 0.190 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3


dynein, axonemal, assembly factor 3


chr1_-_156308018 0.186 ENST00000496684.2
ENST00000368259.2
ENST00000368261.3
ENST00000472765.2
ENST00000533194.1
ENST00000478640.2
CCT3





chaperonin containing TCP1, subunit 3 (gamma)





chr11_-_3400442 0.185 ENST00000429541.2
ENST00000532539.1
ZNF195

zinc finger protein 195

chr14_+_67291158 0.183 ENST00000555456.1
GPHN
gephyrin
chr9_+_130853715 0.180 ENST00000373066.5
ENST00000432073.2
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr4_+_47487285 0.180 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr2_-_27434756 0.180 ENST00000426119.1
ENST00000412471.1
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr18_+_72166564 0.179 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2


CNDP dipeptidase 2 (metallopeptidase M20 family)


chr3_-_179322416 0.178 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr2_-_27435125 0.175 ENST00000414408.1
ENST00000310574.3
SLC5A6

solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

chr15_-_72514866 0.173 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr12_+_104850771 0.173 ENST00000546689.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_-_106098162 0.172 ENST00000337478.1
ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr15_-_34331243 0.171 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr14_-_64846033 0.168 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr19_-_23869999 0.168 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675




zinc finger protein 675




chr1_-_156307992 0.166 ENST00000415548.1
CCT3
chaperonin containing TCP1, subunit 3 (gamma)
chr3_+_32737027 0.166 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr18_+_72167096 0.166 ENST00000324301.8
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr17_+_37617721 0.165 ENST00000584632.1
CDK12
cyclin-dependent kinase 12
chr5_+_169011033 0.162 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr5_+_39520499 0.161 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr12_-_108154925 0.161 ENST00000228437.5
PRDM4
PR domain containing 4
chr16_-_12897642 0.159 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1


calcineurin-like phosphoesterase domain containing 1


chr3_-_179322436 0.155 ENST00000392659.2
ENST00000476781.1
MRPL47

mitochondrial ribosomal protein L47

chr19_+_18668672 0.155 ENST00000601630.1
ENST00000599000.1
ENST00000595073.1
ENST00000596785.1
KXD1



KxDL motif containing 1



chr12_+_104697504 0.155 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr9_+_134065506 0.154 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr17_-_72619869 0.151 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr12_-_13248598 0.150 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr19_+_2785458 0.148 ENST00000307741.6
ENST00000585338.1
THOP1

thimet oligopeptidase 1

chr4_+_78829479 0.147 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr1_+_156308245 0.146 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC


TSSK6 activating co-chaperone


chr13_-_30160925 0.145 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_+_56769924 0.143 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C



RAD51 paralog C



chr14_+_31028348 0.142 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3


G2/M-phase specific E3 ubiquitin protein ligase


chr12_+_110940111 0.142 ENST00000409778.3
RAD9B
RAD9 homolog B (S. pombe)
chrX_+_153775821 0.142 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma




chr5_+_169010638 0.141 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1




spindle apparatus coiled-coil protein 1




chr3_+_137906154 0.140 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
ARMC8


armadillo repeat containing 8


chr11_-_107729504 0.139 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr2_-_27435390 0.138 ENST00000428518.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_+_18668572 0.138 ENST00000540691.1
ENST00000539106.1
ENST00000222307.4
KXD1


KxDL motif containing 1


chr16_+_67143880 0.137 ENST00000219139.3
ENST00000566026.1
C16orf70

chromosome 16 open reading frame 70

chr11_-_107729887 0.136 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr9_+_15552867 0.136 ENST00000535968.1
CCDC171
coiled-coil domain containing 171
chr15_+_72410629 0.136 ENST00000340912.4
ENST00000544171.1
SENP8

SUMO/sentrin specific peptidase family member 8

chr17_-_8113542 0.135 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB


aurora kinase B


chr15_+_66797627 0.135 ENST00000565627.1
ENST00000564179.1
ZWILCH

zwilch kinetochore protein

chr11_-_107729287 0.134 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr5_-_19142450 0.131 ENST00000504827.1
RP11-124N3.3
RP11-124N3.3
chrX_-_142605301 0.131 ENST00000370503.2
SPANXN3
SPANX family, member N3
chr17_-_39526052 0.130 ENST00000251646.3
KRT33B
keratin 33B
chr11_-_7904464 0.128 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5

RP11-35J10.5

chr16_+_67143828 0.128 ENST00000563853.2
ENST00000569914.1
ENST00000569600.1
C16orf70


chromosome 16 open reading frame 70


chr7_+_100551239 0.126 ENST00000319509.7
MUC3A
mucin 3A, cell surface associated
chr16_+_20911174 0.126 ENST00000568663.1
LYRM1
LYR motif containing 1
chr12_+_76653611 0.125 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr6_-_28554977 0.125 ENST00000452236.2
SCAND3
SCAN domain containing 3
chr13_+_50570019 0.125 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr11_+_63606373 0.124 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr3_-_186288097 0.123 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr15_+_72410660 0.122 ENST00000564082.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr19_+_18668616 0.121 ENST00000600372.1
KXD1
KxDL motif containing 1
chr2_+_161993412 0.121 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chr2_+_173955327 0.120 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr5_+_8839844 0.119 ENST00000510229.1
ENST00000506655.1
ENST00000510067.1
RP11-143A12.3


RP11-143A12.3


chr2_+_108994466 0.119 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr1_+_36396677 0.118 ENST00000373191.4
ENST00000397828.2
AGO3

argonaute RISC catalytic component 3

chr7_-_128049955 0.118 ENST00000419067.2
ENST00000378717.4
IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

chr15_+_66797455 0.116 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr13_+_111855414 0.116 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_+_124913930 0.115 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr2_+_101869262 0.115 ENST00000289382.3
CNOT11
CCR4-NOT transcription complex, subunit 11
chr1_-_173176452 0.112 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr5_-_39270725 0.112 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr12_+_123259063 0.111 ENST00000392441.4
ENST00000539171.1
CCDC62

coiled-coil domain containing 62

chr12_+_32832203 0.110 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L









dynamin 1-like









chr20_+_19870167 0.109 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr3_+_72201910 0.109 ENST00000469178.1
ENST00000485404.1
LINC00870

long intergenic non-protein coding RNA 870

chr16_+_31085714 0.108 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646


zinc finger protein 646


chr2_-_201753980 0.107 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3


peptidylprolyl isomerase (cyclophilin)-like 3


chr11_+_61891445 0.107 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP


inner centromere protein antigens 135/155kDa


chr19_+_7011509 0.106 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr1_+_42928945 0.104 ENST00000428554.2
CCDC30
coiled-coil domain containing 30
chr12_-_13248562 0.104 ENST00000457134.2
ENST00000537302.1
GSG1

germ cell associated 1

chr4_-_148605265 0.103 ENST00000541232.1
ENST00000322396.6
PRMT10

protein arginine methyltransferase 10 (putative)

chr2_-_88285309 0.103 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chrX_-_48326683 0.102 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr5_+_56471592 0.099 ENST00000511209.1
GPBP1
GC-rich promoter binding protein 1
chr4_+_56814968 0.099 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chrX_-_48326764 0.098 ENST00000413668.1
ENST00000441948.1
SLC38A5

solute carrier family 38, member 5

chr7_+_90339169 0.098 ENST00000436577.2
CDK14
cyclin-dependent kinase 14
chr22_-_38239808 0.098 ENST00000406423.1
ENST00000424350.1
ENST00000458278.2
ANKRD54


ankyrin repeat domain 54


chr1_+_47603109 0.097 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22


cytochrome P450, family 4, subfamily A, polypeptide 22


chr7_+_64838712 0.097 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92


zinc finger protein 92


chr7_-_27183263 0.097 ENST00000222726.3
HOXA5
homeobox A5
chr12_+_76653682 0.097 ENST00000553247.1
RP11-54A9.1
RP11-54A9.1
chr22_-_32058166 0.096 ENST00000435900.1
ENST00000336566.4
PISD

phosphatidylserine decarboxylase

chr16_+_2273558 0.096 ENST00000301727.4
ENST00000565090.1
ENST00000564139.1
E4F1


E4F transcription factor 1


chr2_+_217277137 0.094 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
SMARCAL1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1


chr16_-_3450963 0.093 ENST00000573327.1
ENST00000571906.1
ENST00000573830.1
ENST00000439568.2
ENST00000422427.2
ENST00000304926.3
ENST00000396852.4
ZSCAN32






zinc finger and SCAN domain containing 32







Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031247 actin rod assembly(GO:0031247)
0.3 2.0 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.7 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.5 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.2 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.2 GO:0090212 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.3 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0 0.1 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.0 GO:0017143 insecticide metabolic process(GO:0017143)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.4 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:1990423 RZZ complex(GO:1990423)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.2 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 2.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.5 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.0 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.0 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 2.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis