Motif ID: HOXC10_HOXD13

Z-value: 0.574

Transcription factors associated with HOXC10_HOXD13:

Gene SymbolEntrez IDGene Name
HOXC10 ENSG00000180818.4 HOXC10
HOXD13 ENSG00000128714.5 HOXD13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXC10hg19_v2_chr12_+_54378923_543789700.665.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXC10_HOXD13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_69180083 1.382 ENST00000328895.4
GKN2
gastrokine 2
chr2_-_69180012 1.151 ENST00000481498.1
GKN2
gastrokine 2
chr3_+_160394940 0.913 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr7_+_22766766 0.852 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr17_-_39538550 0.786 ENST00000394001.1
KRT34
keratin 34
chr3_-_151034734 0.773 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr2_+_158114051 0.684 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr4_-_39033963 0.516 ENST00000381938.3
TMEM156
transmembrane protein 156
chr5_+_147582387 0.512 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr15_-_75017711 0.508 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr4_+_48018781 0.494 ENST00000295461.5
NIPAL1
NIPA-like domain containing 1
chr5_+_147582348 0.458 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr4_+_169013666 0.395 ENST00000359299.3
ANXA10
annexin A10
chr1_+_66458072 0.382 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr9_+_130911723 0.378 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr14_-_69444957 0.370 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1


actinin, alpha 1


chr3_-_52090461 0.358 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr16_+_22501658 0.357 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr6_+_12290586 0.345 ENST00000379375.5
EDN1
endothelin 1
chr14_-_51027838 0.340 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chrX_-_15619076 0.338 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_+_32042131 0.337 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_+_32042105 0.329 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr20_+_37554955 0.324 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr2_+_172309634 0.308 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr11_-_128392085 0.303 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr3_+_30647994 0.293 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr12_-_25801478 0.283 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1



intermediate filament tail domain containing 1



chr12_-_49418407 0.279 ENST00000526209.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr12_-_15038779 0.267 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr15_+_67418047 0.253 ENST00000540846.2
SMAD3
SMAD family member 3
chr1_-_42384343 0.249 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr5_-_94417186 0.249 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr9_+_130911770 0.247 ENST00000372998.1
LCN2
lipocalin 2
chr15_+_63414760 0.246 ENST00000557972.1
LACTB
lactamase, beta
chr4_+_169575875 0.243 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr12_-_56236734 0.243 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr16_-_21863541 0.239 ENST00000543654.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr11_-_796197 0.238 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr4_+_75174180 0.236 ENST00000413830.1
EPGN
epithelial mitogen
chr2_-_37374876 0.236 ENST00000405334.1
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr11_+_101785727 0.234 ENST00000263468.8
KIAA1377
KIAA1377
chr12_+_78359999 0.218 ENST00000550503.1
NAV3
neuron navigator 3
chr12_+_54384370 0.217 ENST00000504315.1
HOXC6
homeobox C6
chr16_+_86229728 0.206 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr1_+_90460661 0.202 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
ZNF326



zinc finger protein 326



chr1_-_43919346 0.200 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI



hydroxypyruvate isomerase (putative)



chr9_-_95640218 0.199 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr1_-_43919573 0.198 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI


hydroxypyruvate isomerase (putative)


chr3_+_69811858 0.194 ENST00000433517.1
MITF
microphthalmia-associated transcription factor
chr13_-_31736132 0.193 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr3_+_30648066 0.193 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr13_-_31736027 0.193 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1


heat shock 105kDa/110kDa protein 1


chr4_+_14113592 0.191 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085



long intergenic non-protein coding RNA 1085



chr6_+_30687978 0.188 ENST00000327892.8
ENST00000435534.1
TUBB

tubulin, beta class I

chr5_-_94417314 0.188 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_14805546 0.183 ENST00000552140.1
NPIPA3
nuclear pore complex interacting protein family, member A3
chr13_-_31736478 0.183 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr6_-_27114577 0.181 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr16_-_21431078 0.179 ENST00000458643.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr4_+_75174204 0.178 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr5_+_135496675 0.178 ENST00000507637.1
SMAD5
SMAD family member 5
chr20_+_19870167 0.172 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr16_+_16429787 0.170 ENST00000331436.4
ENST00000541593.1
AC138969.4

Protein PKD1P1

chr12_+_20963632 0.167 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr17_-_39526052 0.166 ENST00000251646.3
KRT33B
keratin 33B
chr6_+_42847348 0.165 ENST00000493763.1
ENST00000304734.5
RPL7L1

ribosomal protein L7-like 1

chr9_+_82188077 0.164 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_12656715 0.162 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1



spire-type actin nucleation factor 1



chr2_-_151344172 0.161 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr12_-_100486668 0.161 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L




UHRF1 binding protein 1-like




chr7_-_92747269 0.160 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr12_-_52828147 0.159 ENST00000252245.5
KRT75
keratin 75
chr9_+_82187487 0.158 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chr10_-_106240032 0.158 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr15_-_58571445 0.156 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_16472912 0.154 ENST00000530217.2
NPIPA7
nuclear pore complex interacting protein family, member A7
chr11_+_117070037 0.151 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr5_-_142784888 0.148 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chrX_+_56590002 0.147 ENST00000338222.5
UBQLN2
ubiquilin 2
chr18_+_3252265 0.145 ENST00000580887.1
ENST00000536605.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr9_+_21967137 0.143 ENST00000441769.2
C9orf53
chromosome 9 open reading frame 53
chr10_+_69865866 0.143 ENST00000354393.2
MYPN
myopalladin
chrX_-_10851762 0.140 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr6_+_34204642 0.137 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr9_+_82187630 0.134 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_+_45938079 0.134 ENST00000561493.1
SQRDL
sulfide quinone reductase-like (yeast)
chr14_+_73563735 0.132 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr12_-_10321754 0.129 ENST00000539518.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr11_-_27723158 0.127 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr12_-_47219733 0.126 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4


solute carrier family 38, member 4


chr18_+_61445007 0.125 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr5_+_72143988 0.125 ENST00000506351.2
TNPO1
transportin 1
chr3_+_57875738 0.123 ENST00000417128.1
ENST00000438794.1
SLMAP

sarcolemma associated protein

chr3_-_156534754 0.123 ENST00000472943.1
ENST00000473352.1
LINC00886

long intergenic non-protein coding RNA 886

chrX_-_19688475 0.123 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr14_-_50583271 0.123 ENST00000395860.2
ENST00000395859.2
VCPKMT

valosin containing protein lysine (K) methyltransferase

chr5_-_159766528 0.122 ENST00000505287.2
CCNJL
cyclin J-like
chr10_+_48189612 0.121 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr22_-_30642782 0.121 ENST00000249075.3
LIF
leukemia inhibitory factor
chr11_+_129936836 0.120 ENST00000597197.1
AP003041.2
Uncharacterized protein
chr10_-_104913367 0.119 ENST00000423468.2
NT5C2
5'-nucleotidase, cytosolic II
chr10_-_94301107 0.119 ENST00000436178.1
IDE
insulin-degrading enzyme
chr13_-_24007815 0.118 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr10_+_115614370 0.117 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr1_+_162351503 0.117 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr4_+_124571409 0.114 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1


long intergenic non-protein coding RNA 1091


chr17_-_2117600 0.113 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr10_-_47239738 0.113 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chrX_+_24483338 0.112 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr9_+_134065519 0.111 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr3_+_159557637 0.111 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr14_-_35344093 0.110 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr5_+_142286887 0.109 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr11_+_63606373 0.107 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr16_-_12070468 0.106 ENST00000538896.1
RP11-166B2.1
Putative NPIP-like protein LOC729978
chr5_-_142784101 0.106 ENST00000503201.1
ENST00000502892.1
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr12_+_20963647 0.104 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr21_+_30673091 0.104 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr11_-_107729504 0.104 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr16_-_15180257 0.104 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr3_+_107096188 0.103 ENST00000261058.1
CCDC54
coiled-coil domain containing 54
chr9_+_97766469 0.103 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr12_-_118628350 0.103 ENST00000537952.1
ENST00000537822.1
TAOK3

TAO kinase 3

chr18_+_52385068 0.102 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr17_+_37617721 0.101 ENST00000584632.1
CDK12
cyclin-dependent kinase 12
chr8_+_26150628 0.100 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr11_-_107729287 0.099 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr4_+_169633310 0.099 ENST00000510998.1
PALLD
palladin, cytoskeletal associated protein
chr6_+_32812568 0.099 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr9_+_97766409 0.098 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr9_+_108463234 0.098 ENST00000374688.1
TMEM38B
transmembrane protein 38B
chr8_+_92114060 0.097 ENST00000518304.1
LRRC69
leucine rich repeat containing 69
chr3_+_16306837 0.097 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr9_+_115913222 0.097 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr12_-_94673956 0.096 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr2_+_200472779 0.096 ENST00000427045.1
ENST00000419243.1
AC093590.1

AC093590.1

chr7_-_27205136 0.096 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr9_-_16705069 0.096 ENST00000471301.2
BNC2
basonuclin 2
chr16_+_86612112 0.096 ENST00000320241.3
FOXL1
forkhead box L1
chr12_+_64173583 0.094 ENST00000261234.6
TMEM5
transmembrane protein 5
chr14_+_52164820 0.094 ENST00000554167.1
FRMD6
FERM domain containing 6
chr19_+_36706024 0.094 ENST00000443387.2
ZNF146
zinc finger protein 146
chr3_+_15045419 0.092 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr7_-_50860565 0.091 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr1_+_157963063 0.091 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL


kin of IRRE like (Drosophila)


chr15_+_36887069 0.091 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41


chromosome 15 open reading frame 41


chr2_-_197675000 0.090 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr1_+_181057638 0.089 ENST00000367577.4
IER5
immediate early response 5
chr7_+_77428066 0.089 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr10_-_128210005 0.089 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90



chromosome 10 open reading frame 90



chr16_+_1728257 0.089 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L




hematological and neurological expressed 1-like




chr22_+_50981079 0.088 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr4_-_85771168 0.088 ENST00000514071.1
WDFY3
WD repeat and FYVE domain containing 3
chr15_-_78538025 0.087 ENST00000560817.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr6_-_33547975 0.087 ENST00000442998.2
ENST00000360661.5
BAK1

BCL2-antagonist/killer 1

chr12_-_96184533 0.087 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr11_-_107729887 0.087 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr12_+_45686457 0.087 ENST00000441606.2
ANO6
anoctamin 6
chr3_-_37216055 0.087 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr2_+_101591314 0.087 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr16_-_18466642 0.086 ENST00000541810.1
ENST00000531453.2
RP11-1212A22.4

LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1

chr13_-_46626820 0.086 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr6_-_116381918 0.086 ENST00000606080.1
FRK
fyn-related kinase
chr8_+_76452097 0.086 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr12_-_52715179 0.085 ENST00000293670.3
KRT83
keratin 83
chr14_+_31046959 0.085 ENST00000547532.1
ENST00000555429.1
G2E3

G2/M-phase specific E3 ubiquitin protein ligase

chr7_+_77428149 0.084 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr16_+_14844670 0.084 ENST00000553201.1
NPIPA2
nuclear pore complex interacting protein family, member A2
chr1_+_23345930 0.083 ENST00000356634.3
KDM1A
lysine (K)-specific demethylase 1A
chr15_-_71184724 0.083 ENST00000560604.1
THAP10
THAP domain containing 10
chr6_-_33548006 0.082 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr2_-_136288113 0.081 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr18_+_61445205 0.081 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_-_80141328 0.081 ENST00000398291.3
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr6_-_56716686 0.081 ENST00000520645.1
DST
dystonin
chr15_-_55790515 0.081 ENST00000448430.2
ENST00000457155.2
DYX1C1

dyslexia susceptibility 1 candidate 1

chr14_+_62164340 0.081 ENST00000557538.1
ENST00000539097.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr2_-_207078086 0.080 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr7_+_134551583 0.080 ENST00000435928.1
CALD1
caldesmon 1
chr1_+_157963391 0.078 ENST00000359209.6
ENST00000416935.2
KIRREL

kin of IRRE like (Drosophila)

chr9_-_14180778 0.078 ENST00000380924.1
ENST00000543693.1
NFIB

nuclear factor I/B

chr16_+_15031300 0.078 ENST00000328085.6
NPIPA1
nuclear pore complex interacting protein family, member A1
chr12_-_96184913 0.078 ENST00000538383.1
NTN4
netrin 4
chr19_-_54619006 0.078 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr2_-_40657397 0.077 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1





solute carrier family 8 (sodium/calcium exchanger), member 1





chr5_-_130970723 0.077 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr1_+_23345943 0.076 ENST00000400181.4
ENST00000542151.1
KDM1A

lysine (K)-specific demethylase 1A

chr14_-_20774092 0.076 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
TTC5


tetratricopeptide repeat domain 5


chr8_+_77318769 0.075 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr2_-_153032484 0.075 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr12_-_118628315 0.075 ENST00000540561.1
TAOK3
TAO kinase 3
chr17_+_41132564 0.074 ENST00000361677.1
ENST00000589705.1
RUNDC1

RUN domain containing 1

chr7_-_92777606 0.073 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr11_-_104480019 0.073 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1


RP11-886D15.1


chr5_-_13944652 0.071 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr7_-_27219849 0.071 ENST00000396344.4
HOXA10
homeobox A10
chr21_+_39644395 0.071 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr13_-_46626847 0.070 ENST00000242848.4
ENST00000282007.3
ZC3H13

zinc finger CCCH-type containing 13

chr11_-_89956461 0.070 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2 0.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.5 GO:0043449 insecticide metabolic process(GO:0017143) cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.2 0.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.6 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.3 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.2 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.3 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.1 GO:2000097 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 2.2 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.0 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 2.6 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.0 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.0 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.5 PID_ALK1_PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions