Motif ID: HOXB8
Z-value: 0.926
Transcription factors associated with HOXB8:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| HOXB8 | ENSG00000120068.5 | HOXB8 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXB8 | hg19_v2_chr17_-_46690839_46690884 | 0.54 | 1.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.2 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.2 | 0.7 | GO:0003147 | neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) |
| 0.2 | 1.1 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.2 | 0.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.2 | 0.9 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.2 | 0.5 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.2 | 1.8 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.2 | 0.5 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.2 | 0.5 | GO:0046356 | acetyl-CoA catabolic process(GO:0046356) |
| 0.1 | 0.4 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 1.1 | GO:0060437 | lung growth(GO:0060437) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 0.3 | GO:0006147 | guanine catabolic process(GO:0006147) |
| 0.1 | 0.5 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623) |
| 0.1 | 0.8 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.1 | 0.5 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 0.1 | 0.7 | GO:0060356 | leucine import(GO:0060356) |
| 0.1 | 1.7 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.1 | 0.3 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.1 | 0.9 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 1.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 0.6 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 0.5 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 0.5 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.1 | 0.2 | GO:1903410 | lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410) |
| 0.1 | 0.2 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.1 | 0.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.4 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.1 | 0.2 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.1 | 0.2 | GO:1990654 | sebum secreting cell proliferation(GO:1990654) |
| 0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 0.1 | 0.2 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.1 | 0.4 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 0.1 | 0.2 | GO:0034553 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
| 0.1 | 0.5 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.1 | 0.4 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.1 | 0.2 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.1 | 0.3 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.7 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.2 | GO:0031296 | B cell costimulation(GO:0031296) |
| 0.1 | 0.6 | GO:0010748 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.1 | 0.2 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.1 | 0.2 | GO:0046081 | dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081) |
| 0.1 | 0.2 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 0.1 | 0.4 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.1 | 0.2 | GO:0007388 | anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388) |
| 0.0 | 0.2 | GO:0055092 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.0 | 0.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.3 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.0 | 0.2 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.0 | 0.1 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 0.0 | 0.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.0 | 0.3 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.0 | 0.1 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.0 | 0.2 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.0 | 0.4 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 0.1 | GO:1901076 | positive regulation of engulfment of apoptotic cell(GO:1901076) |
| 0.0 | 0.3 | GO:0045959 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) |
| 0.0 | 0.3 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 0.3 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.8 | GO:0046520 | sphingoid biosynthetic process(GO:0046520) |
| 0.0 | 0.2 | GO:0051037 | regulation of transcription involved in meiotic cell cycle(GO:0051037) |
| 0.0 | 0.2 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.0 | 0.2 | GO:0021683 | cerebellar granular layer morphogenesis(GO:0021683) |
| 0.0 | 0.3 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.0 | 0.2 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
| 0.0 | 0.2 | GO:1904647 | response to rotenone(GO:1904647) |
| 0.0 | 0.6 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.1 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) negative regulation of fatty acid transport(GO:2000192) |
| 0.0 | 0.1 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.0 | 0.2 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.2 | GO:0014038 | regulation of Schwann cell differentiation(GO:0014038) |
| 0.0 | 0.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.0 | 0.7 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.1 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.0 | 0.1 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 0.2 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.0 | 0.2 | GO:0032796 | uropod organization(GO:0032796) |
| 0.0 | 0.2 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.0 | 0.3 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.0 | 0.1 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) |
| 0.0 | 2.0 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.0 | 0.8 | GO:0060850 | regulation of transcription involved in cell fate commitment(GO:0060850) |
| 0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.0 | 0.2 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.0 | 0.1 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.0 | 0.1 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.0 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 1.2 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.1 | GO:0061325 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) cell proliferation involved in outflow tract morphogenesis(GO:0061325) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.0 | 0.4 | GO:0003356 | regulation of cilium beat frequency(GO:0003356) |
| 0.0 | 0.6 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.0 | 0.1 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 0.0 | 0.1 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.0 | 0.1 | GO:1904882 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.0 | 0.2 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
| 0.0 | 0.1 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.0 | 0.1 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.0 | 0.4 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.3 | GO:2000334 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.0 | 0.1 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 0.0 | 0.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.0 | 0.5 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.1 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.0 | 0.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 0.1 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.0 | 0.1 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 0.0 | 0.3 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.0 | 0.2 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 0.0 | 0.1 | GO:0044829 | modulation by host of viral genome replication(GO:0044827) positive regulation by host of viral genome replication(GO:0044829) |
| 0.0 | 1.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.4 | GO:0006554 | lysine catabolic process(GO:0006554) |
| 0.0 | 0.2 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.0 | 0.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.0 | 0.8 | GO:0050974 | detection of mechanical stimulus involved in sensory perception(GO:0050974) |
| 0.0 | 0.4 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.0 | 0.2 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.0 | 0.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 0.1 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.0 | 0.0 | GO:0007500 | mesodermal cell fate determination(GO:0007500) |
| 0.0 | 0.2 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.0 | 0.1 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.1 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
| 0.0 | 0.2 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.1 | GO:0039007 | pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121) |
| 0.0 | 0.2 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.2 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.0 | 0.3 | GO:0017085 | response to insecticide(GO:0017085) |
| 0.0 | 0.2 | GO:1904179 | positive regulation of adipose tissue development(GO:1904179) |
| 0.0 | 0.2 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 0.0 | 0.1 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.0 | 0.3 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
| 0.0 | 0.1 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
| 0.0 | 0.2 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.0 | 0.1 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.0 | 0.3 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.0 | 0.2 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.0 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.0 | 1.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.1 | GO:0070895 | transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895) |
| 0.0 | 0.0 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.0 | 0.8 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.1 | GO:0045209 | MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209) |
| 0.0 | 0.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.0 | 0.0 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.0 | 0.2 | GO:0015824 | proline transport(GO:0015824) |
| 0.0 | 0.0 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.0 | 0.1 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.0 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 0.0 | 0.1 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.0 | 0.0 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 0.0 | 0.0 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.0 | 0.2 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.1 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.0 | 0.2 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 0.0 | 0.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.1 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.0 | 0.2 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 0.7 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.0 | 0.2 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 1.0 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.0 | 0.1 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.0 | 0.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.1 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.3 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.2 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.0 | 0.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
| 0.0 | 0.2 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.0 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.1 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 1.0 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.0 | 0.1 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.1 | GO:2000329 | negative regulation of T-helper 17 cell lineage commitment(GO:2000329) |
| 0.0 | 0.1 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.0 | 0.1 | GO:0070836 | caveola assembly(GO:0070836) regulation of vasculogenesis(GO:2001212) |
| 0.0 | 0.3 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.3 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.2 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.1 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.0 | 0.1 | GO:0001709 | cell fate determination(GO:0001709) |
| 0.0 | 0.1 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 0.4 | GO:0031055 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.0 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.1 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 0.7 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.2 | 0.7 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.2 | 1.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 0.9 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 1.8 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 0.6 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.1 | 0.5 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 0.1 | 0.3 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 0.6 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 0.3 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.1 | 0.5 | GO:0001740 | Barr body(GO:0001740) |
| 0.0 | 0.2 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
| 0.0 | 0.3 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.0 | 0.7 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 0.4 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.0 | 0.5 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.3 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.0 | 0.6 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.3 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.0 | 0.4 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.2 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 0.0 | 0.2 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 0.1 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.0 | 0.1 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.4 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.0 | 0.2 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.0 | 0.1 | GO:0034657 | GID complex(GO:0034657) |
| 0.0 | 0.2 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.3 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
| 0.0 | 0.1 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.0 | 0.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.0 | 0.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.1 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
| 0.0 | 0.3 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.2 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.3 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.2 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.0 | 0.1 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.2 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.0 | 0.1 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 1.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 3.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.2 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.5 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 1.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.1 | GO:0070369 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907) |
| 0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.3 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.1 | GO:1990923 | PET complex(GO:1990923) |
| 0.0 | 0.1 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 0.2 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.1 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.0 | 0.1 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.0 | 0.4 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.2 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 1.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.0 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.0 | 0.5 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.1 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 1.9 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.0 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 0.2 | GO:0031932 | TORC2 complex(GO:0031932) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.2 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.3 | 1.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.2 | 1.8 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.2 | 0.5 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.1 | 0.7 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 0.6 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.1 | 0.6 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 0.3 | GO:0008892 | guanine deaminase activity(GO:0008892) |
| 0.1 | 0.3 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.1 | 1.1 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 0.4 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 0.1 | 0.4 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.1 | 0.5 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.1 | 0.3 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 0.2 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.1 | 0.2 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.1 | 0.8 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.5 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 1.5 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 0.3 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.1 | 0.2 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 0.1 | 0.2 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.1 | 1.0 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.0 | 0.8 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.2 | GO:0005289 | high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292) |
| 0.0 | 0.2 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.0 | 1.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.0 | 0.2 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.0 | 0.1 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.0 | 0.8 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.0 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.2 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.9 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.4 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.2 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.0 | 0.2 | GO:0035276 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) ethanol binding(GO:0035276) |
| 0.0 | 0.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.0 | 0.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.0 | 0.3 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.0 | 0.6 | GO:0008430 | selenium binding(GO:0008430) |
| 0.0 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.2 | GO:0050294 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.0 | 0.1 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.0 | 0.1 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.0 | 2.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 0.3 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.3 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.0 | 0.3 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.1 | GO:0052870 | alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.0 | 1.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
| 0.0 | 0.1 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.0 | 0.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.0 | 0.1 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.0 | 0.1 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.0 | 0.2 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.0 | 0.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.1 | GO:0045550 | geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017) |
| 0.0 | 0.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.4 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.0 | 0.3 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.3 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.1 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.0 | 0.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 0.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.1 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.2 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 0.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.0 | 0.1 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 0.0 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.0 | 0.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.1 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.2 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.1 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.0 | 0.2 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.0 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.0 | 0.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
| 0.0 | 0.1 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.0 | 0.1 | GO:0004803 | transposase activity(GO:0004803) |
| 0.0 | 0.1 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.0 | 0.0 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 2.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.0 | 0.7 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.0 | 0.2 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.0 | 0.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 0.1 | GO:0018636 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) |
| 0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.9 | GO:1990939 | ATP-dependent microtubule motor activity(GO:1990939) |
| 0.0 | 0.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.3 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.0 | GO:0030760 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.3 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.3 | GO:0071949 | FAD binding(GO:0071949) |
| 0.0 | 2.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.4 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.1 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
| 0.0 | 1.1 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.2 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.9 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.2 | ST_STAT3_PATHWAY | STAT3 Pathway |
| 0.0 | 0.3 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.2 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.3 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.4 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins |
| 0.2 | 0.2 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.1 | 4.7 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 0.9 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.1 | REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 1.0 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 1.0 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.6 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.9 | REACTOME_SOS_MEDIATED_SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.0 | 0.7 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.6 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.4 | REACTOME_OPSINS | Genes involved in Opsins |
| 0.0 | 0.9 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.6 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 0.3 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 1.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.2 | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.6 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 1.0 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.3 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 0.3 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.2 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.2 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.1 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.4 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.4 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.3 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.2 | REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA | Genes involved in Processing of Capped Intronless Pre-mRNA |
| 0.0 | 0.4 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 1.7 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.1 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |


