Motif ID: HOXB2_UNCX_HOXD3

Z-value: 0.871

Transcription factors associated with HOXB2_UNCX_HOXD3:

Gene SymbolEntrez IDGene Name
HOXB2 ENSG00000173917.9 HOXB2
HOXD3 ENSG00000128652.7 HOXD3
UNCX ENSG00000164853.8 UNCX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD3hg19_v2_chr2_+_177001685_1770016850.392.9e-01Click!
HOXB2hg19_v2_chr17_-_46623441_466234410.383.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_183538319 4.019 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr7_-_92777606 3.407 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr4_-_76944621 1.853 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_-_183560011 1.652 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr4_-_76957214 1.636 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_-_183559693 1.393 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr11_+_35222629 1.376 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr13_+_49551020 1.308 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr10_+_91152303 1.157 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr15_+_59910132 1.150 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_-_150738261 1.131 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr13_-_41593425 1.044 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_22766766 1.031 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6






interleukin 6 (interferon, beta 2)






chr9_-_32526299 1.006 ENST00000379882.1
ENST00000379883.2
DDX58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

chr12_+_104337515 0.937 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_-_121476750 0.935 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr12_+_78359999 0.879 ENST00000550503.1
NAV3
neuron navigator 3
chr5_+_35852797 0.873 ENST00000508941.1
IL7R
interleukin 7 receptor
chr12_-_15103621 0.867 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_69201705 0.839 ENST00000377938.2
GKN1
gastrokine 1
chr1_+_68150744 0.796 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chr5_-_150473127 0.792 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr3_+_149191723 0.787 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr4_-_169239921 0.770 ENST00000514995.1
ENST00000393743.3
DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr9_+_130911723 0.769 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr2_+_149402989 0.716 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr7_-_92747269 0.709 ENST00000446617.1
ENST00000379958.2
SAMD9

sterile alpha motif domain containing 9

chr3_+_158787041 0.649 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr2_-_207078154 0.641 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr9_+_130911770 0.590 ENST00000372998.1
LCN2
lipocalin 2
chr1_-_109399682 0.587 ENST00000369995.3
ENST00000370001.3
AKNAD1

AKNA domain containing 1

chr5_-_35938674 0.582 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr22_+_36649056 0.568 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
APOL1



apolipoprotein L, 1



chr10_-_105110831 0.568 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chrX_+_18725758 0.560 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr4_+_75174204 0.549 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr16_+_53133070 0.547 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_102456277 0.547 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_75174180 0.546 ENST00000413830.1
EPGN
epithelial mitogen
chr6_-_32157947 0.526 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr7_-_28220354 0.523 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr8_-_19614810 0.522 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_-_151034734 0.518 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr10_-_28571015 0.517 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr15_+_63188009 0.509 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr16_+_69345243 0.501 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr14_+_52164820 0.498 ENST00000554167.1
FRMD6
FERM domain containing 6
chr7_+_73245193 0.494 ENST00000340958.2
CLDN4
claudin 4
chr10_-_105845674 0.486 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr5_+_68860949 0.474 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr10_-_105110890 0.472 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr12_-_30887948 0.471 ENST00000433722.2
CAPRIN2
caprin family member 2
chr14_-_106926724 0.457 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr18_+_32556892 0.450 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chr7_+_55433131 0.439 ENST00000254770.2
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr2_-_207078086 0.435 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr1_+_160370344 0.433 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr3_+_159557637 0.433 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr6_-_138866823 0.432 ENST00000342260.5
NHSL1
NHS-like 1
chr4_-_36245561 0.432 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_62164340 0.432 ENST00000557538.1
ENST00000539097.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr3_+_158991025 0.431 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr10_+_6821545 0.429 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr22_+_18632666 0.423 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr11_+_102188224 0.420 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chrX_-_46187069 0.413 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr2_+_172309634 0.406 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr12_-_15815626 0.406 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_66300446 0.401 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_41448820 0.400 ENST00000372616.1
CTPS1
CTP synthase 1
chr6_+_126221034 0.396 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr12_-_118628350 0.396 ENST00000537952.1
ENST00000537822.1
TAOK3

TAO kinase 3

chr7_-_33102399 0.393 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr18_-_61311485 0.392 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4


serpin peptidase inhibitor, clade B (ovalbumin), member 4


chr1_+_100817262 0.390 ENST00000455467.1
CDC14A
cell division cycle 14A
chr11_+_123430948 0.388 ENST00000529432.1
ENST00000534764.1
GRAMD1B

GRAM domain containing 1B

chr6_-_15548591 0.381 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr8_+_22424551 0.379 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr5_+_125759140 0.377 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_+_57279004 0.375 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr7_-_33102338 0.372 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr3_-_33686925 0.367 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr11_-_104827425 0.367 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr10_-_104866395 0.358 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr6_+_106988986 0.351 ENST00000457437.1
ENST00000535438.1
AIM1

absent in melanoma 1

chr1_+_162351503 0.350 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr5_+_89770664 0.346 ENST00000503973.1
ENST00000399107.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr6_-_15586238 0.343 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr22_-_29107919 0.341 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr11_+_102188272 0.340 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr6_+_47666275 0.336 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr4_+_79567057 0.335 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2

long intergenic non-protein coding RNA 1094

chr10_+_70980051 0.335 ENST00000354624.5
ENST00000395086.2
HKDC1

hexokinase domain containing 1

chr4_+_150999418 0.330 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr4_+_169013666 0.328 ENST00000359299.3
ANXA10
annexin A10
chrM_+_10464 0.327 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr17_-_29641104 0.326 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr1_+_81106951 0.323 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr14_-_23652849 0.321 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8



solute carrier family 7 (amino acid transporter light chain, L system), member 8



chr4_+_66536248 0.317 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1

RP11-807H7.1

chr1_+_66796401 0.315 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_+_61654271 0.315 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr7_-_111424462 0.314 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr1_-_165414414 0.309 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr17_-_62097927 0.309 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2







intercellular adhesion molecule 2







chr12_-_112123524 0.303 ENST00000327551.6
BRAP
BRCA1 associated protein
chrM_+_10758 0.297 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr13_-_30160925 0.297 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_149887377 0.295 ENST00000367419.5
GINM1
glycoprotein integral membrane 1
chr17_+_18625336 0.288 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr10_-_92681033 0.288 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr18_+_61637159 0.287 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8




serpin peptidase inhibitor, clade B (ovalbumin), member 8




chr4_+_38665810 0.286 ENST00000261438.5
ENST00000514033.1
KLF3

Kruppel-like factor 3 (basic)

chr11_+_101983176 0.286 ENST00000524575.1
YAP1
Yes-associated protein 1
chr14_+_39944025 0.282 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr1_-_149900122 0.281 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr5_+_125758865 0.280 ENST00000542322.1
ENST00000544396.1
GRAMD3

GRAM domain containing 3

chr11_+_35201826 0.280 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr19_-_56110859 0.277 ENST00000221665.3
ENST00000592585.1
FIZ1

FLT3-interacting zinc finger 1

chr7_-_139763521 0.276 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr2_+_190541153 0.271 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR



ankyrin and armadillo repeat containing



chr8_-_131399110 0.271 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr6_+_30029008 0.270 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1



zinc ribbon domain containing 1



chr10_-_115904361 0.269 ENST00000428953.1
ENST00000543782.1
C10orf118

chromosome 10 open reading frame 118

chr9_-_95298254 0.269 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr8_-_90996459 0.269 ENST00000517337.1
ENST00000409330.1
NBN

nibrin

chr10_-_105845536 0.268 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr5_+_125758813 0.267 ENST00000285689.3
ENST00000515200.1
GRAMD3

GRAM domain containing 3

chr12_+_28410128 0.266 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr14_+_67831576 0.266 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_-_166060382 0.266 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr4_+_56815102 0.262 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr4_+_110749143 0.262 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr1_+_66797687 0.261 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr1_-_24469602 0.260 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr9_+_125132803 0.260 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_-_64211112 0.258 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr12_-_27924209 0.257 ENST00000381273.3
MANSC4
MANSC domain containing 4
chr5_-_148929848 0.256 ENST00000504676.1
ENST00000515435.1
CSNK1A1

casein kinase 1, alpha 1

chr5_-_147211226 0.253 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr8_-_101571964 0.253 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46





ankyrin repeat domain 46





chr12_-_118628315 0.251 ENST00000540561.1
TAOK3
TAO kinase 3
chr7_-_143929936 0.250 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr13_-_54706954 0.250 ENST00000606706.1
ENST00000607494.1
ENST00000427299.2
ENST00000423442.2
ENST00000451744.1
LINC00458




long intergenic non-protein coding RNA 458




chr11_+_100784231 0.249 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr4_-_89205705 0.249 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K


protein phosphatase, Mg2+/Mn2+ dependent, 1K


chr13_+_76413852 0.249 ENST00000533809.2
LMO7
LIM domain 7
chr7_+_129932974 0.247 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr11_-_4414880 0.246 ENST00000254436.7
ENST00000543625.1
TRIM21

tripartite motif containing 21

chr6_+_126240442 0.245 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7


nuclear receptor coactivator 7


chr12_+_113354341 0.245 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_106751436 0.244 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr10_+_94451574 0.244 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr10_-_22498950 0.244 ENST00000422359.2
EBLN1
endogenous Bornavirus-like nucleoprotein 1
chr10_+_90660832 0.242 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr1_-_232651312 0.242 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chrX_-_154033686 0.239 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1


membrane protein, palmitoylated 1, 55kDa


chr4_-_152149033 0.238 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr5_-_13944652 0.233 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr2_-_207082624 0.232 ENST00000458440.1
ENST00000437420.1
GPR1

G protein-coupled receptor 1

chr7_-_104909435 0.232 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr9_-_16728161 0.232 ENST00000603713.1
ENST00000603313.1
BNC2

basonuclin 2

chrX_-_19988382 0.230 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr6_-_28973037 0.227 ENST00000377179.3
ZNF311
zinc finger protein 311
chr2_-_70780770 0.226 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA


transforming growth factor, alpha


chr1_+_156163880 0.225 ENST00000359511.4
ENST00000423538.2
SLC25A44

solute carrier family 25, member 44

chr12_+_20963632 0.224 ENST00000540853.1
ENST00000261196.2
SLCO1B3

solute carrier organic anion transporter family, member 1B3

chr8_-_19615382 0.223 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_-_8000872 0.223 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr12_-_49581152 0.222 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr5_+_147648393 0.221 ENST00000511106.1
ENST00000398450.4
SPINK13

serine peptidase inhibitor, Kazal type 13 (putative)

chr5_+_66300464 0.221 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_-_82957433 0.220 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_+_13049413 0.220 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr17_-_78194716 0.220 ENST00000576707.1
SGSH
N-sulfoglucosamine sulfohydrolase
chr11_+_86502085 0.219 ENST00000527521.1
PRSS23
protease, serine, 23
chr5_+_89770696 0.219 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr13_+_76378407 0.217 ENST00000447038.1
LMO7
LIM domain 7
chrX_+_107334983 0.216 ENST00000457035.1
ENST00000545696.1
ATG4A

autophagy related 4A, cysteine peptidase

chr17_-_15501932 0.215 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr9_+_125133315 0.214 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr17_+_41132564 0.213 ENST00000361677.1
ENST00000589705.1
RUNDC1

RUN domain containing 1

chr10_+_94594351 0.212 ENST00000371552.4
EXOC6
exocyst complex component 6
chr7_-_80548493 0.211 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_-_49245916 0.210 ENST00000552512.1
ENST00000551468.1
DDX23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr7_-_111424506 0.210 ENST00000450156.1
ENST00000494651.2
DOCK4

dedicator of cytokinesis 4

chr9_+_103204553 0.209 ENST00000334943.6
ENST00000502978.1
TMEFF1
MSANTD3-TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
MSANTD3-TMEFF1 readthrough
chr4_-_66536057 0.209 ENST00000273854.3
EPHA5
EPH receptor A5
chr12_+_27398584 0.208 ENST00000543246.1
STK38L
serine/threonine kinase 38 like
chr6_+_18387570 0.207 ENST00000259939.3
RNF144B
ring finger protein 144B
chrX_-_73512177 0.207 ENST00000603672.1
ENST00000418855.1
FTX

FTX transcript, XIST regulator (non-protein coding)

chr2_-_214016314 0.206 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr14_+_29299437 0.206 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1



CTD-2384A14.1



chr12_+_75784850 0.206 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2





GLI pathogenesis-related 1 like 2





chr19_-_36822551 0.205 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr16_+_10837643 0.205 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
NUBP1


nucleotide binding protein 1


chr5_-_142780280 0.204 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_42538480 0.204 ENST00000280876.6
GXYLT1
glucoside xylosyltransferase 1
chr5_+_36606700 0.204 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_+_25875662 0.203 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1


nucleoporin like 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.0 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.3 0.9 GO:0031247 actin rod assembly(GO:0031247)
0.3 4.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 1.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 3.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 1.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 7.1 GO:0045730 respiratory burst(GO:0045730)
0.2 1.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.8 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.4 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0061009 common bile duct development(GO:0061009)
0.1 0.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.4 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.2 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.4 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.9 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.3 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.3 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.2 GO:0070487 monocyte aggregation(GO:0070487)
0.1 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.7 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.5 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.4 GO:0042262 DNA protection(GO:0042262)
0.0 0.2 GO:0071874 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752) response to rapamycin(GO:1901355)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.1 GO:1900098 epithelial cell differentiation involved in salivary gland development(GO:0060690) epithelial cell maturation involved in salivary gland development(GO:0060691) regulation of plasma cell differentiation(GO:1900098) positive regulation of plasma cell differentiation(GO:1900100) regulation of lactation(GO:1903487) positive regulation of lactation(GO:1903489)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.0 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) positive regulation of cyclic nucleotide catabolic process(GO:0030807) regulation of cAMP catabolic process(GO:0030820) positive regulation of cAMP catabolic process(GO:0030822) regulation of purine nucleotide catabolic process(GO:0033121) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.6 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.0 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.0 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.0 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 1.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.0 GO:0031664 lipopolysaccharide-mediated signaling pathway(GO:0031663) regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0008380 RNA splicing(GO:0008380)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.1 GO:0032010 phagolysosome(GO:0032010)
0.2 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 1.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.1 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.3 GO:0097451 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.6 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:1990752 microtubule end(GO:1990752)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 7.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.8 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.4 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.2 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.2 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.3 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.3 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.0 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.0 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST_STAT3_PATHWAY STAT3 Pathway
0.1 7.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 3.3 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 1.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.1 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 7.2 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.3 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.8 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.9 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway