Motif ID: HOXA2_HOXB1

Z-value: 0.822

Transcription factors associated with HOXA2_HOXB1:

Gene SymbolEntrez IDGene Name
HOXA2 ENSG00000105996.5 HOXA2
HOXB1 ENSG00000120094.6 HOXB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA2hg19_v2_chr7_-_27142290_271424300.098.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_52105495 2.058 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr4_-_90756769 1.367 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr4_-_90757364 1.308 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr6_-_64029879 1.110 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr2_-_190044480 1.007 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr5_+_162864575 1.000 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1






cyclin G1






chr1_-_8763278 0.952 ENST00000468247.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr10_-_105615164 0.799 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chrX_-_13835461 0.773 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chrX_-_13835147 0.748 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr1_-_205391178 0.637 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr12_+_57610562 0.570 ENST00000349394.5
NXPH4
neurexophilin 4
chr12_-_15038779 0.555 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr2_+_36923901 0.549 ENST00000457137.2
VIT
vitrin
chr11_-_111782696 0.548 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr13_-_110438914 0.510 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr2_+_36923933 0.494 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr2_+_36923830 0.487 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr5_+_147582387 0.410 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr15_-_74501310 0.396 ENST00000423167.2
ENST00000432245.2
STRA6

stimulated by retinoic acid 6

chr2_-_154335300 0.365 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_+_47421933 0.345 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr15_-_64673630 0.343 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr15_-_74501360 0.329 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr15_-_64673665 0.322 ENST00000300035.4
KIAA0101
KIAA0101
chr8_-_128231299 0.305 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr10_+_18689637 0.296 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr2_-_44588694 0.274 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr2_-_44588679 0.268 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr1_-_108507631 0.251 ENST00000527011.1
ENST00000370056.4
VAV3

vav 3 guanine nucleotide exchange factor

chr1_-_217804377 0.239 ENST00000366935.3
ENST00000366934.3
GPATCH2

G patch domain containing 2

chr20_+_34802295 0.206 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr5_+_147582348 0.203 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr3_+_150264458 0.195 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr3_+_150264555 0.191 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr4_-_102267953 0.188 ENST00000523694.2
ENST00000507176.1
PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

chr20_+_34742650 0.184 ENST00000373945.1
ENST00000338074.2
EPB41L1

erythrocyte membrane protein band 4.1-like 1

chr9_-_73029540 0.176 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr3_+_189507460 0.172 ENST00000434928.1
TP63
tumor protein p63
chr2_+_242089833 0.169 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7



protein phosphatase 1, regulatory subunit 7



chr11_-_126174186 0.169 ENST00000524964.1
RP11-712L6.5
Uncharacterized protein
chr6_-_159065741 0.169 ENST00000367085.3
ENST00000367089.3
DYNLT1

dynein, light chain, Tctex-type 1

chr10_+_124320156 0.150 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chr5_-_179045199 0.145 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr17_-_57229155 0.142 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr5_-_125930929 0.140 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chrX_-_30993201 0.138 ENST00000288422.2
ENST00000378932.2
TAB3

TGF-beta activated kinase 1/MAP3K7 binding protein 3

chr11_-_111782484 0.135 ENST00000533971.1
CRYAB
crystallin, alpha B
chr19_-_45735138 0.134 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr7_-_120497178 0.132 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr22_-_39151463 0.130 ENST00000405510.1
ENST00000433561.1
SUN2

Sad1 and UNC84 domain containing 2

chrX_-_13835398 0.130 ENST00000475307.1
GPM6B
glycoprotein M6B
chr20_+_42574317 0.127 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr2_-_200322723 0.122 ENST00000417098.1
SATB2
SATB homeobox 2
chrX_+_99899180 0.122 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr14_-_21516590 0.120 ENST00000555026.1
NDRG2
NDRG family member 2
chr17_-_46623441 0.115 ENST00000330070.4
HOXB2
homeobox B2
chr5_-_125930877 0.115 ENST00000510111.2
ENST00000509270.1
ALDH7A1

aldehyde dehydrogenase 7 family, member A1

chr1_+_12524965 0.109 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr11_-_93583697 0.108 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr2_-_23747214 0.107 ENST00000430988.1
AC011239.1
Uncharacterized protein
chr3_-_156877997 0.107 ENST00000295926.3
CCNL1
cyclin L1
chr2_-_200323414 0.104 ENST00000443023.1
SATB2
SATB homeobox 2
chr17_+_21729593 0.102 ENST00000581769.1
ENST00000584755.1
UBBP4

ubiquitin B pseudogene 4

chr8_-_79717750 0.102 ENST00000263851.4
ENST00000379113.2
IL7

interleukin 7

chr14_-_81893734 0.099 ENST00000555447.1
STON2
stonin 2
chr5_-_145895753 0.085 ENST00000311104.2
GPR151
G protein-coupled receptor 151
chr12_+_7023491 0.081 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chr2_+_54684327 0.079 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr12_-_118490217 0.077 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr7_+_79765071 0.076 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_+_79495397 0.074 ENST00000417245.2
ENST00000334850.7
FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chrX_+_41583408 0.070 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr11_-_2162162 0.069 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_-_101730061 0.068 ENST00000519100.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr14_+_68189190 0.066 ENST00000539142.1
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr8_-_143961236 0.065 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1


cytochrome P450, family 11, subfamily B, polypeptide 1


chr6_+_151561085 0.063 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr16_-_67427389 0.063 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr1_-_67390474 0.062 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78



WD repeat domain 78



chr10_+_124320195 0.062 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr9_+_132099158 0.059 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr20_-_45976816 0.057 ENST00000441977.1
ZMYND8
zinc finger, MYND-type containing 8
chr17_+_48609903 0.054 ENST00000268933.3
EPN3
epsin 3
chr14_-_54425475 0.053 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr18_+_56887381 0.052 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
GRP


gastrin-releasing peptide


chr11_+_68228186 0.052 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3












protein phosphatase 6, regulatory subunit 3












chr7_+_86273218 0.050 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr11_+_133902547 0.048 ENST00000529070.1
RP11-713P17.3
RP11-713P17.3
chr2_+_114647504 0.046 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chrX_+_95939711 0.045 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr6_-_113754604 0.044 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr3_-_187388173 0.044 ENST00000287641.3
SST
somatostatin
chr11_+_57365150 0.043 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr12_-_28124903 0.042 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr6_+_151561506 0.041 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_143999259 0.041 ENST00000323110.2
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr3_-_150264272 0.040 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1


stress-associated endoplasmic reticulum protein 1


chr2_+_26624775 0.037 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr2_-_145278475 0.037 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr2_-_242089677 0.037 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr9_+_44868935 0.036 ENST00000448436.2
RP11-160N1.10
RP11-160N1.10
chr16_+_25703274 0.035 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr15_-_93616892 0.035 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA


repulsive guidance molecule family member a


chr12_+_10658489 0.035 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr3_+_189507523 0.034 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr20_+_21283941 0.031 ENST00000377191.3
ENST00000430571.2
XRN2

5'-3' exoribonuclease 2

chrX_+_95939638 0.031 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2


diaphanous-related formin 2


chr15_+_81591757 0.030 ENST00000558332.1
IL16
interleukin 16
chr4_-_5021164 0.029 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
CYTL1


cytokine-like 1


chr9_-_73477826 0.027 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3





transient receptor potential cation channel, subfamily M, member 3





chr2_+_176995011 0.026 ENST00000548663.1
ENST00000450510.2
HOXD8

homeobox D8

chr6_+_73331520 0.026 ENST00000342056.2
ENST00000355194.4
KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5

chr21_+_19617140 0.025 ENST00000299295.2
ENST00000338326.3
CHODL

chondrolectin

chr5_+_133861790 0.025 ENST00000395003.1
PHF15
jade family PHD finger 2
chr1_+_52082751 0.023 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9



oxysterol binding protein-like 9



chr6_+_33387830 0.023 ENST00000293748.5
SYNGAP1
synaptic Ras GTPase activating protein 1
chr10_-_98945264 0.022 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr2_+_68961905 0.021 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr17_-_27418537 0.020 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr19_-_49944806 0.020 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr10_-_100995603 0.019 ENST00000370552.3
ENST00000370549.1
HPSE2

heparanase 2

chr10_-_65028938 0.019 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr6_+_33387868 0.019 ENST00000418600.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr17_-_42276574 0.017 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr2_+_68961934 0.017 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr12_+_57390745 0.015 ENST00000600202.1
HBCBP
HBcAg-binding protein; Uncharacterized protein
chr7_+_26591441 0.013 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2


AC004947.2


chr2_-_145277882 0.013 ENST00000465070.1
ENST00000444559.1
ZEB2

zinc finger E-box binding homeobox 2

chr19_-_41356347 0.013 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr10_-_46342921 0.012 ENST00000448048.2
AGAP4
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
chr6_+_33388013 0.010 ENST00000449372.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr20_+_21284416 0.010 ENST00000539513.1
XRN2
5'-3' exoribonuclease 2
chr1_+_67390578 0.009 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1






mesoderm induction early response 1, transcriptional regulator






chr9_-_101471479 0.009 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_+_191046810 0.008 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr12_-_88423164 0.006 ENST00000298699.2
ENST00000550553.1
C12orf50

chromosome 12 open reading frame 50

chr7_-_100881041 0.006 ENST00000412417.1
ENST00000414035.1
CLDN15

claudin 15

chr20_+_30467600 0.006 ENST00000375934.4
ENST00000375922.4
TTLL9

tubulin tyrosine ligase-like family, member 9

chr1_-_223536679 0.004 ENST00000608996.1
SUSD4
sushi domain containing 4
chr19_+_37997812 0.004 ENST00000542455.1
ENST00000587143.1
ZNF793

zinc finger protein 793

chr5_-_145252531 0.004 ENST00000377976.1
GRXCR2
glutaredoxin, cysteine rich 2
chr2_+_68962014 0.004 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr9_+_113431029 0.004 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK


muscle, skeletal, receptor tyrosine kinase


chr12_+_7022909 0.002 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr10_-_65028817 0.001 ENST00000542921.1
JMJD1C
jumonji domain containing 1C

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 1.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.7 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.8 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.3 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.5 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.6 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0048389 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 1.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.0 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:1990175 EH domain binding(GO:1990175)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.0 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.5 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions