Motif ID: HNF4G

Z-value: 0.790


Transcription factors associated with HNF4G:

Gene SymbolEntrez IDGene Name
HNF4G ENSG00000164749.7 HNF4G

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HNF4Ghg19_v2_chr8_+_76452097_76452126-0.541.3e-01Click!


Activity profile for motif HNF4G.

activity profile for motif HNF4G


Sorted Z-values histogram for motif HNF4G

Sorted Z-values for motif HNF4G



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4G

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_134092561 0.601 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2


angiomotin like 2


chr19_+_38779778 0.590 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4

serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4

chr16_+_2255710 0.551 ENST00000397124.1
ENST00000565250.1
MLST8

MTOR associated protein, LST8 homolog (S. cerevisiae)

chr16_+_88872176 0.525 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr19_-_1592828 0.522 ENST00000592012.1
MBD3
methyl-CpG binding domain protein 3
chr16_+_2255841 0.519 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr11_-_63330842 0.499 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr22_+_37415700 0.463 ENST00000397129.1
MPST
mercaptopyruvate sulfurtransferase
chr1_-_183538319 0.448 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr16_+_56642041 0.413 ENST00000245185.5
MT2A
metallothionein 2A
chr17_+_1944790 0.397 ENST00000575162.1
DPH1
diphthamide biosynthesis 1
chr17_-_73840774 0.385 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr8_-_145159083 0.382 ENST00000398712.2
SHARPIN
SHANK-associated RH domain interactor
chr11_-_60719213 0.381 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr11_-_1780261 0.372 ENST00000427721.1
RP11-295K3.1
RP11-295K3.1
chr5_-_134369973 0.369 ENST00000265340.7
PITX1
paired-like homeodomain 1
chr7_+_2281843 0.364 ENST00000356714.1
ENST00000397049.1
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr17_-_17740325 0.340 ENST00000338854.5
SREBF1
sterol regulatory element binding transcription factor 1
chr22_+_37415676 0.338 ENST00000401419.3
MPST
mercaptopyruvate sulfurtransferase
chr12_+_121163538 0.335 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr22_+_37415776 0.329 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
MPST


mercaptopyruvate sulfurtransferase


chr10_+_103986085 0.319 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr16_+_29973351 0.314 ENST00000602948.1
ENST00000279396.6
ENST00000575829.2
ENST00000561899.2
TMEM219



transmembrane protein 219



chr22_+_37415728 0.312 ENST00000404802.3
MPST
mercaptopyruvate sulfurtransferase
chr17_-_17740287 0.306 ENST00000355815.4
ENST00000261646.5
SREBF1

sterol regulatory element binding transcription factor 1

chr17_+_74732889 0.303 ENST00000591864.1
MFSD11
major facilitator superfamily domain containing 11
chr22_+_19950060 0.302 ENST00000449653.1
COMT
catechol-O-methyltransferase
chr21_+_45725050 0.299 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr19_-_56632592 0.297 ENST00000587279.1
ENST00000270459.3
ZNF787

zinc finger protein 787

chr9_-_112970436 0.297 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chrX_-_153599578 0.293 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr17_-_17494972 0.292 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
PEMT


phosphatidylethanolamine N-methyltransferase


chr4_+_89378261 0.291 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chrX_-_153279697 0.291 ENST00000444254.1
IRAK1
interleukin-1 receptor-associated kinase 1
chr11_+_66115304 0.291 ENST00000531602.1
RP11-867G23.8
Uncharacterized protein
chr20_-_44485835 0.289 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8


acyl-CoA thioesterase 8


chr11_-_67236691 0.289 ENST00000544903.1
ENST00000308022.2
ENST00000393877.3
ENST00000452789.2
TMEM134



transmembrane protein 134



chr7_+_2281882 0.288 ENST00000397046.1
ENST00000397048.1
ENST00000454650.1
NUDT1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr12_+_3068957 0.285 ENST00000543035.1
TEAD4
TEA domain family member 4
chr1_-_230513367 0.281 ENST00000321327.2
ENST00000525115.1
PGBD5

piggyBac transposable element derived 5

chr16_-_89768097 0.274 ENST00000289805.5
ENST00000335360.7
SPATA2L

spermatogenesis associated 2-like

chr16_+_84209738 0.262 ENST00000564928.1
DNAAF1
dynein, axonemal, assembly factor 1
chr9_-_139839064 0.259 ENST00000325285.3
ENST00000428398.1
FBXW5

F-box and WD repeat domain containing 5

chr17_+_80186908 0.254 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
SLC16A3



solute carrier family 16 (monocarboxylate transporter), member 3



chr19_-_633576 0.254 ENST00000588649.2
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr8_-_145642267 0.251 ENST00000301305.3
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr17_-_76123101 0.250 ENST00000392467.3
TMC6
transmembrane channel-like 6
chr11_+_842808 0.247 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chr9_+_139839711 0.247 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr5_-_180230830 0.241 ENST00000427865.2
ENST00000514283.1
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr17_-_73840415 0.240 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D


unc-13 homolog D (C. elegans)


chr1_+_24120143 0.238 ENST00000374501.1
LYPLA2
lysophospholipase II
chr19_-_5785630 0.237 ENST00000590343.1
ENST00000586012.1
DUS3L
CTB-54O9.9
dihydrouridine synthase 3-like (S. cerevisiae)
Uncharacterized protein
chr11_+_65337901 0.236 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1





Sjogren syndrome/scleroderma autoantigen 1





chr5_-_131826457 0.235 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr14_+_105952648 0.235 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr8_-_145641864 0.233 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr16_-_57832004 0.232 ENST00000562503.1
KIFC3
kinesin family member C3
chr1_-_24126892 0.231 ENST00000374497.3
ENST00000425913.1
GALE

UDP-galactose-4-epimerase

chr11_-_1782625 0.225 ENST00000438213.1
CTSD
cathepsin D
chr22_-_37415475 0.225 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
TST


thiosulfate sulfurtransferase (rhodanese)


chr11_-_45939374 0.224 ENST00000533151.1
ENST00000241041.3
PEX16

peroxisomal biogenesis factor 16

chr10_+_102759545 0.220 ENST00000454422.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr7_+_143080063 0.220 ENST00000446634.1
ZYX
zyxin
chr17_+_72772621 0.220 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104




transmembrane protein 104




chr16_-_57831914 0.220 ENST00000421376.2
KIFC3
kinesin family member C3
chr19_-_10613361 0.219 ENST00000591039.1
ENST00000591419.1
KEAP1

kelch-like ECH-associated protein 1

chr6_-_160166218 0.215 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr3_+_11267691 0.215 ENST00000413416.1
HRH1
histamine receptor H1
chr17_+_48423453 0.214 ENST00000017003.2
ENST00000509778.1
ENST00000507602.1
XYLT2


xylosyltransferase II


chr19_+_42773371 0.213 ENST00000571942.2
CIC
capicua transcriptional repressor
chr10_+_81065975 0.213 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr11_-_45939565 0.212 ENST00000525192.1
ENST00000378750.5
PEX16

peroxisomal biogenesis factor 16

chr9_+_139221880 0.207 ENST00000392945.3
ENST00000440944.1
GPSM1

G-protein signaling modulator 1

chr16_-_67194201 0.207 ENST00000345057.4
TRADD
TNFRSF1A-associated via death domain
chr19_-_4535233 0.207 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr17_-_2318731 0.206 ENST00000609667.1
AC006435.1
Uncharacterized protein
chr11_-_66496430 0.204 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr7_-_642261 0.204 ENST00000400758.2
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_+_811073 0.204 ENST00000382862.3
ENST00000563651.1
MSLN

mesothelin

chr12_+_58120044 0.203 ENST00000542466.2
AGAP2-AS1
AGAP2 antisense RNA 1
chr12_-_31158902 0.201 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4


RP11-551L14.4


chr16_+_30662085 0.201 ENST00000569864.1
PRR14
proline rich 14
chr17_-_79304150 0.201 ENST00000574093.1
TMEM105
transmembrane protein 105
chr6_-_42110342 0.199 ENST00000356542.5
C6orf132
chromosome 6 open reading frame 132
chr1_-_209824643 0.196 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr16_+_3115378 0.196 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
IL32




interleukin 32




chr16_+_30662050 0.195 ENST00000568754.1
PRR14
proline rich 14
chr16_+_29840929 0.194 ENST00000566252.1
MVP
major vault protein
chr9_+_137298396 0.193 ENST00000540193.1
RXRA
retinoid X receptor, alpha
chr17_-_73840614 0.192 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr1_+_17906970 0.189 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_1553346 0.186 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr16_-_57514277 0.186 ENST00000562008.1
ENST00000567214.1
DOK4

docking protein 4

chr19_-_15235906 0.186 ENST00000600984.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr9_+_139690784 0.185 ENST00000338005.6
KIAA1984
coiled-coil domain containing 183
chr1_-_44482979 0.183 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr9_-_130639997 0.172 ENST00000373176.1
AK1
adenylate kinase 1
chr19_+_50353944 0.170 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1



prostate tumor overexpressed 1



chr19_+_49617581 0.169 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr14_+_55595960 0.169 ENST00000554715.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr17_+_78152274 0.168 ENST00000344227.2
ENST00000570421.1
CARD14

caspase recruitment domain family, member 14

chr19_-_4400415 0.167 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1


SH3-domain GRB2-like 1


chr9_+_139886846 0.166 ENST00000371620.3
C9orf142
chromosome 9 open reading frame 142
chr16_-_57831676 0.166 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3


kinesin family member C3


chrX_-_153744507 0.163 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
FAM3A





family with sequence similarity 3, member A





chr20_-_62199427 0.161 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr19_-_14016877 0.159 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57


chromosome 19 open reading frame 57


chr22_+_45072925 0.159 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr15_+_45926919 0.158 ENST00000561735.1
ENST00000260324.7
SQRDL

sulfide quinone reductase-like (yeast)

chr19_-_49121054 0.158 ENST00000546623.1
ENST00000084795.5
RPL18

ribosomal protein L18

chr17_+_33570055 0.157 ENST00000299977.4
ENST00000542451.1
ENST00000592325.1
SLFN5


schlafen family member 5


chr12_+_113354341 0.156 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_-_42806919 0.156 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3


platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)


chr20_-_36794902 0.154 ENST00000373403.3
TGM2
transglutaminase 2
chr11_+_67033881 0.153 ENST00000308595.5
ENST00000526285.1
ADRBK1

adrenergic, beta, receptor kinase 1

chr11_-_45940343 0.151 ENST00000532681.1
PEX16
peroxisomal biogenesis factor 16
chr16_+_3115611 0.151 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
IL32
















interleukin 32
















chr1_-_21625486 0.150 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr19_+_50183032 0.150 ENST00000527412.1
PRMT1
protein arginine methyltransferase 1
chr1_+_35246775 0.146 ENST00000373366.2
GJB3
gap junction protein, beta 3, 31kDa
chr16_+_2034692 0.146 ENST00000567719.1
GFER
growth factor, augmenter of liver regeneration
chr22_-_32034376 0.146 ENST00000431201.1
PISD
phosphatidylserine decarboxylase
chr11_+_64052692 0.146 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr19_+_10197463 0.146 ENST00000590378.1
ENST00000397881.3
C19orf66

chromosome 19 open reading frame 66

chr19_+_47852538 0.145 ENST00000328771.4
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr11_-_65381643 0.144 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr17_+_48624450 0.144 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20


spermatogenesis associated 20


chr2_+_242498135 0.143 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr1_+_104104379 0.143 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr22_-_42526802 0.141 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6


cytochrome P450, family 2, subfamily D, polypeptide 6


chr1_-_2345236 0.140 ENST00000508384.1
PEX10
peroxisomal biogenesis factor 10
chr1_+_160370344 0.140 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr19_-_48867171 0.140 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143


transmembrane protein 143


chr15_+_75315896 0.139 ENST00000342932.3
ENST00000564923.1
ENST00000569562.1
ENST00000568649.1
PPCDC



phosphopantothenoylcysteine decarboxylase



chr14_-_62162541 0.137 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr17_-_38256973 0.136 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr1_+_26605618 0.136 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_22263790 0.135 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr6_-_31864977 0.134 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr2_+_10442993 0.134 ENST00000423674.1
ENST00000307845.3
HPCAL1

hippocalcin-like 1

chr10_-_71892555 0.133 ENST00000307864.1
AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr14_-_24911971 0.133 ENST00000555365.1
ENST00000399395.3
SDR39U1

short chain dehydrogenase/reductase family 39U, member 1

chr11_+_64009072 0.133 ENST00000535135.1
ENST00000394540.3
FKBP2

FK506 binding protein 2, 13kDa

chr19_+_39616410 0.132 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr11_-_66725837 0.132 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr11_-_77899634 0.131 ENST00000526208.1
ENST00000529350.1
ENST00000530018.1
ENST00000528776.1
KCTD21



potassium channel tetramerization domain containing 21



chr11_+_67071050 0.130 ENST00000376757.5
SSH3
slingshot protein phosphatase 3
chr3_+_37284824 0.130 ENST00000431105.1
GOLGA4
golgin A4
chr4_-_7044657 0.129 ENST00000310085.4
CCDC96
coiled-coil domain containing 96
chr17_+_77030267 0.129 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr14_+_61449076 0.128 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr16_+_67313412 0.128 ENST00000379344.3
ENST00000568621.1
ENST00000450733.1
ENST00000567938.1
PLEKHG4



pleckstrin homology domain containing, family G (with RhoGef domain) member 4



chr16_+_3014217 0.128 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr16_-_68000717 0.128 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr22_+_35695793 0.126 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1





target of myb1 (chicken)





chr19_+_7985198 0.126 ENST00000221573.6
ENST00000595637.1
SNAPC2

small nuclear RNA activating complex, polypeptide 2, 45kDa

chr19_+_18942720 0.126 ENST00000262803.5
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr22_-_32034409 0.125 ENST00000429683.1
PISD
phosphatidylserine decarboxylase
chr17_+_76164639 0.123 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2




synaptogyrin 2




chr1_+_35247859 0.122 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr19_+_10196981 0.122 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr19_-_42758040 0.122 ENST00000593944.1
ERF
Ets2 repressor factor
chr11_+_64052944 0.121 ENST00000535675.1
ENST00000543383.1
GPR137

G protein-coupled receptor 137

chr22_+_30163340 0.120 ENST00000330029.6
ENST00000401406.3
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr16_+_3115323 0.120 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
IL32




interleukin 32




chr19_-_5292781 0.120 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr8_+_27491572 0.118 ENST00000301904.3
SCARA3
scavenger receptor class A, member 3
chr12_-_54813229 0.117 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_+_63742050 0.117 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr2_+_241544834 0.116 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35


G protein-coupled receptor 35


chr11_-_66496655 0.116 ENST00000527010.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr19_+_18942761 0.116 ENST00000599848.1
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr7_+_150759634 0.114 ENST00000392826.2
ENST00000461735.1
SLC4A2

solute carrier family 4 (anion exchanger), member 2

chr19_+_18496957 0.114 ENST00000252809.3
GDF15
growth differentiation factor 15
chr5_-_180235755 0.114 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr17_-_74023291 0.113 ENST00000586740.1
EVPL
envoplakin
chr15_+_89010923 0.113 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr16_+_30936971 0.113 ENST00000565690.1
FBXL19
F-box and leucine-rich repeat protein 19
chr14_-_21562648 0.112 ENST00000555270.1
ZNF219
zinc finger protein 219
chr1_-_26633480 0.112 ENST00000450041.1
UBXN11
UBX domain protein 11
chr19_-_30199516 0.112 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr19_+_6464243 0.111 ENST00000600229.1
ENST00000356762.3
CRB3

crumbs homolog 3 (Drosophila)

chr3_+_53195517 0.110 ENST00000487897.1
PRKCD
protein kinase C, delta
chr17_+_78193443 0.109 ENST00000577155.1
SLC26A11
solute carrier family 26 (anion exchanger), member 11
chr19_+_41119323 0.109 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
LTBP4


latent transforming growth factor beta binding protein 4


chr4_+_6271558 0.109 ENST00000503569.1
ENST00000226760.1
WFS1

Wolfram syndrome 1 (wolframin)

chrX_-_153744434 0.109 ENST00000369643.1
ENST00000393572.1
FAM3A

family with sequence similarity 3, member A

chr17_-_73839792 0.109 ENST00000590762.1
UNC13D
unc-13 homolog D (C. elegans)
chr3_+_48507621 0.108 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr16_+_2303738 0.106 ENST00000454671.1
AC009065.1
Uncharacterized protein
chr14_-_23623577 0.105 ENST00000422941.2
ENST00000453702.1
SLC7A8

solute carrier family 7 (amino acid transporter light chain, L system), member 8

chr19_+_1285890 0.104 ENST00000344663.3
MUM1
melanoma associated antigen (mutated) 1
chr11_-_61596753 0.103 ENST00000448607.1
ENST00000421879.1
FADS1

fatty acid desaturase 1

chr20_-_36794938 0.103 ENST00000453095.1
TGM2
transglutaminase 2
chr8_-_144952631 0.102 ENST00000525985.1
EPPK1
epiplakin 1
chr21_-_44898015 0.102 ENST00000332440.3
LINC00313
long intergenic non-protein coding RNA 313
chr11_+_67070919 0.101 ENST00000308127.4
ENST00000308298.7
SSH3

slingshot protein phosphatase 3

chr16_+_4743688 0.100 ENST00000304301.6
ENST00000586252.1
NUDT16L1

nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1

chr15_+_63682335 0.100 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1

RP11-321G12.1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.2 0.9 GO:0002432 granuloma formation(GO:0002432)
0.2 0.6 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.1 GO:0090345 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.7 GO:0006203 dGTP catabolic process(GO:0006203)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.4 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.4 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.6 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 1.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:2001293 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0 0.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704) frontal suture morphogenesis(GO:0060364)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.0 GO:0021938 ventral midline development(GO:0007418) cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 1.1 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 0.7 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.3 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.6 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0047017 prostaglandin-F synthase activity(GO:0047017)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.0 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol