Motif ID: HNF1A_HNF1B

Z-value: 0.365

Transcription factors associated with HNF1A_HNF1B:

Gene SymbolEntrez IDGene Name
HNF1A ENSG00000135100.13 HNF1A
HNF1B ENSG00000108753.8 HNF1B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v2_chr12_+_121416340_121416371-0.732.7e-02Click!
HNF1Bhg19_v2_chr17_-_36105009_361050600.541.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_110723134 1.068 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr4_-_110723335 1.064 ENST00000394634.2
CFI
complement factor I
chr4_-_110723194 0.973 ENST00000394635.3
CFI
complement factor I
chr10_+_99344071 0.424 ENST00000370647.4
ENST00000370646.4
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr3_-_157221128 0.251 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr11_-_111649074 0.250 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr11_-_111649015 0.231 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr1_+_207277590 0.215 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr1_+_207277632 0.198 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr5_+_176513895 0.193 ENST00000503708.1
ENST00000393648.2
ENST00000514472.1
ENST00000502906.1
ENST00000292410.3
ENST00000510911.1
FGFR4





fibroblast growth factor receptor 4





chr16_+_20775358 0.161 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr5_+_176514413 0.144 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr18_-_48346415 0.143 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr5_+_176513868 0.143 ENST00000292408.4
FGFR4
fibroblast growth factor receptor 4
chr16_-_20587599 0.135 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
ACSM2B







acyl-CoA synthetase medium-chain family member 2B







chr2_-_47572105 0.134 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr9_-_94712434 0.132 ENST00000375708.3
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr6_+_31707725 0.126 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5






mutS homolog 5






chr11_-_83393429 0.125 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_116833500 0.125 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr17_+_1646130 0.125 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2




serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2




chr1_+_229406847 0.123 ENST00000366690.4
RAB4A
RAB4A, member RAS oncogene family
chr5_-_138718973 0.119 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr17_+_4692230 0.116 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr12_-_91574142 0.109 ENST00000547937.1
DCN
decorin
chr7_+_120629653 0.107 ENST00000450913.2
ENST00000340646.5
CPED1

cadherin-like and PC-esterase domain containing 1

chr11_-_117170403 0.101 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr14_+_21156915 0.100 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_168464875 0.100 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr1_+_104159999 0.096 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr11_-_83393303 0.096 ENST00000398304.1
ENST00000420775.2
DLG2

discs, large homolog 2 (Drosophila)

chr10_+_5135981 0.096 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr1_+_84767289 0.094 ENST00000394834.3
ENST00000370669.1
SAMD13

sterile alpha motif domain containing 13

chr17_+_48823896 0.093 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr8_-_95220775 0.089 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr8_-_17752996 0.086 ENST00000381841.2
ENST00000427924.1
FGL1

fibrinogen-like 1

chr10_+_99344104 0.085 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr12_-_54653313 0.085 ENST00000550411.1
ENST00000439541.2
CBX5

chromobox homolog 5

chr14_+_65171099 0.083 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_87248975 0.082 ENST00000409310.2
ENST00000355705.3
PLGLB1

plasminogen-like B1

chr19_+_11350278 0.081 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr3_-_157221357 0.081 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr4_-_69434245 0.076 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr3_+_187930491 0.075 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_+_135340859 0.073 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr4_-_22444733 0.073 ENST00000508133.1
GPR125
G protein-coupled receptor 125
chr10_-_75226166 0.071 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr4_+_8201091 0.070 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr11_-_83393457 0.069 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr22_-_32651326 0.069 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr13_+_27825706 0.069 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr12_-_39837192 0.067 ENST00000361961.3
ENST00000395670.3
KIF21A

kinesin family member 21A

chr4_+_159442878 0.067 ENST00000307765.5
ENST00000423548.1
RXFP1

relaxin/insulin-like family peptide receptor 1

chr20_+_57414795 0.066 ENST00000371098.2
ENST00000371075.3
GNAS

GNAS complex locus

chr20_+_57414743 0.066 ENST00000313949.7
GNAS
GNAS complex locus
chr7_+_130126165 0.065 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr4_-_987164 0.064 ENST00000398520.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr3_-_196911002 0.061 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_+_234668894 0.061 ENST00000608383.1
ENST00000360418.3
ENST00000305208.5
UGT1A1

UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8

UDP glucuronosyltransferase 1 family, polypeptide A1
chr14_+_65171315 0.061 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_157221380 0.060 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr6_+_106534192 0.059 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chrX_+_99899180 0.058 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_+_104293028 0.058 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr1_+_55505184 0.058 ENST00000302118.5
PCSK9
proprotein convertase subtilisin/kexin type 9
chr20_+_43029911 0.056 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A


hepatocyte nuclear factor 4, alpha


chr5_-_111093167 0.056 ENST00000446294.2
ENST00000419114.2
NREP

neuronal regeneration related protein

chr14_-_94759361 0.056 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_+_130126012 0.054 ENST00000341441.5
MEST
mesoderm specific transcript
chr14_+_39703112 0.054 ENST00000555143.1
ENST00000280082.3
MIA2

melanoma inhibitory activity 2

chr4_+_159443090 0.053 ENST00000343542.5
ENST00000470033.1
RXFP1

relaxin/insulin-like family peptide receptor 1

chr2_-_180129484 0.053 ENST00000428443.3
SESTD1
SEC14 and spectrin domains 1
chr2_-_228244013 0.052 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr10_+_111765562 0.052 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr4_-_109541610 0.052 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr7_-_87856303 0.051 ENST00000394641.3
SRI
sorcin
chr14_-_94759408 0.050 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_141264597 0.050 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC


short coiled-coil protein


chr17_+_79953310 0.049 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr17_+_41363854 0.049 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A




transmembrane protein 106A




chr7_-_87856280 0.048 ENST00000490437.1
ENST00000431660.1
SRI

sorcin

chr12_+_25205568 0.048 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr13_-_103719196 0.047 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr17_+_35732955 0.046 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr14_-_54425475 0.045 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr17_+_48823975 0.043 ENST00000513969.1
ENST00000503728.1
LUC7L3

LUC7-like 3 (S. cerevisiae)

chr14_-_94759595 0.043 ENST00000261994.4
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_-_49466686 0.042 ENST00000273598.3
ENST00000436744.2
NICN1

nicolin 1

chr12_+_25205666 0.040 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr7_-_44580861 0.039 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1



NPC1-like 1



chr4_-_109541539 0.039 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1


RPL34 antisense RNA 1 (head to head)


chr2_-_55920952 0.036 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr14_-_57960545 0.036 ENST00000526336.1
ENST00000216445.3
C14orf105

chromosome 14 open reading frame 105

chr3_-_164796269 0.035 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr7_-_6098770 0.034 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
EIF2AK1


eukaryotic translation initiation factor 2-alpha kinase 1


chr19_-_43099070 0.034 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr1_-_229406746 0.032 ENST00000429227.1
ENST00000436334.1
RP5-1061H20.4

RP5-1061H20.4

chr16_-_14109841 0.032 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5

CTD-2135D7.5

chr8_+_20054878 0.032 ENST00000276390.2
ENST00000519667.1
ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

chr12_-_8693539 0.032 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr11_+_64323098 0.032 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr9_-_215744 0.031 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr3_-_126327398 0.030 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr10_-_38146510 0.030 ENST00000395867.3
ZNF248
zinc finger protein 248
chr11_+_20620946 0.029 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr14_-_94854926 0.029 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1


chr5_-_35195338 0.029 ENST00000509839.1
PRLR
prolactin receptor
chr16_+_81272287 0.029 ENST00000425577.2
ENST00000564552.1
BCMO1

beta-carotene 15,15'-monooxygenase 1

chr5_+_1225470 0.028 ENST00000324642.3
ENST00000296821.4
SLC6A18

solute carrier family 6 (neutral amino acid transporter), member 18

chrX_+_48660107 0.028 ENST00000376643.2
HDAC6
histone deacetylase 6
chr4_+_159443024 0.027 ENST00000448688.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr8_-_116681686 0.027 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr19_-_38916839 0.026 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4




RAS guanyl releasing protein 4




chr21_-_19775973 0.026 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr1_-_110284384 0.026 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr12_+_100750846 0.026 ENST00000323346.5
SLC17A8
solute carrier family 17 (vesicular glutamate transporter), member 8
chr18_-_2982869 0.026 ENST00000584915.1
LPIN2
lipin 2
chr3_-_107596910 0.025 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635












long intergenic non-protein coding RNA 635












chr16_+_20462783 0.025 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
ACSM2A








acyl-CoA synthetase medium-chain family member 2A








chr6_-_113953705 0.025 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr5_+_175976324 0.025 ENST00000261944.5
CDHR2
cadherin-related family member 2
chr19_-_11639931 0.024 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT





ECSIT signalling integrator





chr16_-_55909255 0.024 ENST00000290567.9
CES5A
carboxylesterase 5A
chr19_+_50016610 0.024 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_-_55909272 0.024 ENST00000319165.9
CES5A
carboxylesterase 5A
chr22_-_22337204 0.024 ENST00000430142.1
ENST00000357179.5
TOP3B

topoisomerase (DNA) III beta

chr17_+_35732916 0.023 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr6_+_47624172 0.023 ENST00000507065.1
ENST00000296862.1
GPR111

G protein-coupled receptor 111

chr3_+_66271410 0.022 ENST00000336733.6
SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr10_-_72648541 0.022 ENST00000299299.3
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr16_+_67552303 0.022 ENST00000562116.1
FAM65A
family with sequence similarity 65, member A
chr7_-_47579188 0.022 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3



tensin 3



chr3_+_38307293 0.021 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr3_+_141043050 0.021 ENST00000509842.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_+_120629085 0.020 ENST00000428526.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr19_+_6464243 0.020 ENST00000600229.1
ENST00000356762.3
CRB3

crumbs homolog 3 (Drosophila)

chr16_-_55909211 0.020 ENST00000520435.1
CES5A
carboxylesterase 5A
chr4_-_1166954 0.019 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
SPON2


spondin 2, extracellular matrix protein


chr4_-_129207942 0.019 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr6_-_25930819 0.019 ENST00000360488.3
SLC17A2
solute carrier family 17, member 2
chr6_-_29343068 0.019 ENST00000396806.3
OR12D3
olfactory receptor, family 12, subfamily D, member 3
chr19_+_29097595 0.019 ENST00000587961.1
AC079466.1
AC079466.1
chr8_+_42873548 0.018 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr4_-_129208030 0.018 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr2_+_38177620 0.018 ENST00000402091.3
RMDN2
regulator of microtubule dynamics 2
chr4_+_3443614 0.018 ENST00000382774.3
ENST00000511533.1
HGFAC

HGF activator

chr12_+_21284118 0.018 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr4_-_155511887 0.018 ENST00000302053.3
ENST00000403106.3
FGA

fibrinogen alpha chain

chr2_-_162931052 0.017 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr9_+_140125385 0.017 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_-_11639910 0.017 ENST00000588998.1
ENST00000586149.1
ECSIT

ECSIT signalling integrator

chr17_+_26800296 0.016 ENST00000444914.3
ENST00000314669.5
SLC13A2

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

chr9_+_22646189 0.016 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr7_-_150020750 0.015 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr22_-_30968813 0.014 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1


galactose-3-O-sulfotransferase 1


chr3_+_186383741 0.014 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr1_-_114430169 0.014 ENST00000393316.3
BCL2L15
BCL2-like 15
chr11_+_46740730 0.014 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2


coagulation factor II (thrombin)


chr16_+_21244986 0.013 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr19_+_6464502 0.013 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr15_+_58724184 0.013 ENST00000433326.2
LIPC
lipase, hepatic
chr12_-_91546926 0.012 ENST00000550758.1
DCN
decorin
chr22_-_22337154 0.012 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B






topoisomerase (DNA) III beta






chr14_+_95027772 0.012 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4

SERPINA5

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

chr9_+_140125209 0.012 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr1_+_205197304 0.012 ENST00000358024.3
TMCC2
transmembrane and coiled-coil domain family 2
chr20_+_42187608 0.011 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr10_-_101690650 0.011 ENST00000543621.1
DNMBP
dynamin binding protein
chr10_+_115312825 0.011 ENST00000537906.1
ENST00000541666.1
HABP2

hyaluronan binding protein 2

chr15_-_42343388 0.011 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr9_-_13165457 0.011 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr10_-_38146482 0.011 ENST00000374648.3
ZNF248
zinc finger protein 248
chr6_-_25930904 0.011 ENST00000377850.3
SLC17A2
solute carrier family 17, member 2
chr4_+_100495864 0.011 ENST00000265517.5
ENST00000422897.2
MTTP

microsomal triglyceride transfer protein

chr7_-_47578840 0.011 ENST00000450444.1
TNS3
tensin 3
chr5_+_40841410 0.011 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr1_+_104198640 0.010 ENST00000422549.1
AMY1A
amylase, alpha 1A (salivary)
chr3_+_180319918 0.010 ENST00000296015.4
ENST00000491380.1
ENST00000412756.2
ENST00000382584.4
TTC14



tetratricopeptide repeat domain 14



chr22_-_30970498 0.010 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr9_-_116861337 0.009 ENST00000374118.3
KIF12
kinesin family member 12
chr17_+_44803922 0.009 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr22_+_32439019 0.009 ENST00000266088.4
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr21_-_47575481 0.009 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr10_+_115312766 0.008 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr7_-_50633078 0.008 ENST00000444124.2
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_-_36020531 0.008 ENST00000440579.1
ENST00000494948.1
KIAA0319L

KIAA0319-like

chr5_+_140772381 0.008 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr3_+_38307313 0.007 ENST00000450935.2
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr1_+_48688357 0.007 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9



solute carrier family 5 (sodium/sugar cotransporter), member 9



chr7_-_155601766 0.007 ENST00000430104.1
SHH
sonic hedgehog
chr7_-_150020578 0.006 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr20_+_42187682 0.006 ENST00000373092.3
ENST00000373077.1
SGK2

serum/glucocorticoid regulated kinase 2

chr14_+_24590560 0.006 ENST00000558325.1
RP11-468E2.6
RP11-468E2.6
chr1_+_119911396 0.006 ENST00000457318.1
HAO2
hydroxyacid oxidase 2 (long chain)
chr1_+_63063152 0.006 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr15_-_99057551 0.006 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr4_-_74486347 0.005 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr16_-_420514 0.005 ENST00000199706.8
MRPL28
mitochondrial ribosomal protein L28
chr6_+_54173227 0.005 ENST00000259782.4
ENST00000370864.3
TINAG

tubulointerstitial nephritis antigen

chr3_+_72200408 0.005 ENST00000473713.1
LINC00870
long intergenic non-protein coding RNA 870

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903412 response to bile acid(GO:1903412)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 3.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:2000625 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0015747 urate transport(GO:0015747)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate