Motif ID: HMBOX1

Z-value: 1.355


Transcription factors associated with HMBOX1:

Gene SymbolEntrez IDGene Name
HMBOX1 ENSG00000147421.13 HMBOX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HMBOX1hg19_v2_chr8_+_28748099_28748142-0.581.0e-01Click!


Activity profile for motif HMBOX1.

activity profile for motif HMBOX1


Sorted Z-values histogram for motif HMBOX1

Sorted Z-values for motif HMBOX1



Network of associatons between targets according to the STRING database.



First level regulatory network of HMBOX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_110723134 3.376 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr4_-_110723194 2.976 ENST00000394635.3
CFI
complement factor I
chr2_-_183387064 1.852 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr7_+_101460882 1.763 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr2_+_36923901 1.420 ENST00000457137.2
VIT
vitrin
chr12_-_10588539 1.367 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2

NKG2-E
killer cell lectin-like receptor subfamily C, member 2

Uncharacterized protein
chr2_+_36923933 1.364 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chrX_+_16964985 1.237 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr15_+_79603479 1.231 ENST00000424155.2
ENST00000536821.1
TMED3

transmembrane emp24 protein transport domain containing 3

chr4_-_90759440 1.108 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_+_128095945 0.949 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr12_-_113658892 0.942 ENST00000299732.2
ENST00000416617.2
IQCD

IQ motif containing D

chr12_+_122018697 0.936 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr2_+_27994567 0.892 ENST00000379666.3
ENST00000296102.3
MRPL33

mitochondrial ribosomal protein L33

chr3_-_149095652 0.878 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr4_-_140477928 0.877 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr8_-_63951730 0.861 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr17_-_26903900 0.858 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr7_+_128095900 0.853 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr6_-_27114577 0.835 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr16_-_3422283 0.806 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr3_-_151176497 0.781 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr4_-_186877502 0.776 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr9_-_73029540 0.768 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr1_-_9970227 0.755 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chrX_-_115594160 0.726 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr12_-_54673871 0.702 ENST00000209875.4
CBX5
chromobox homolog 5
chr3_-_49142504 0.690 ENST00000306125.6
ENST00000420147.2
QARS

glutaminyl-tRNA synthetase

chr5_-_137667459 0.682 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
CDC25C




cell division cycle 25C




chr2_+_128458514 0.675 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr12_-_113658826 0.654 ENST00000546692.1
IQCD
IQ motif containing D
chr1_+_153940713 0.652 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4


cAMP responsive element binding protein 3-like 4


chr1_+_207943667 0.652 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chr10_-_24911746 0.651 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr12_+_72080253 0.634 ENST00000549735.1
TMEM19
transmembrane protein 19
chr12_+_47473369 0.631 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr2_-_37501692 0.631 ENST00000443977.1
PRKD3
protein kinase D3
chr7_-_111202511 0.605 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMMP2L


IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)


chr4_-_140477910 0.603 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr5_-_137667526 0.592 ENST00000503022.1
CDC25C
cell division cycle 25C
chr12_+_4758264 0.591 ENST00000266544.5
NDUFA9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr9_-_23779367 0.590 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr16_-_30597000 0.582 ENST00000470110.1
ENST00000395216.2
ZNF785

zinc finger protein 785

chrX_-_74376108 0.570 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7




ATP-binding cassette, sub-family B (MDR/TAP), member 7




chr8_+_120885949 0.556 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr3_-_141747459 0.554 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chrX_-_21776281 0.539 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr17_+_48172639 0.538 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr1_+_240408560 0.509 ENST00000441342.1
ENST00000545751.1
FMN2

formin 2

chr12_-_56727676 0.501 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr6_+_112408768 0.496 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr2_-_14541060 0.486 ENST00000418420.1
ENST00000417751.1
LINC00276

long intergenic non-protein coding RNA 276

chr1_+_153940741 0.478 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr17_-_57229155 0.467 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chrX_-_115828156 0.466 ENST00000446495.1
RP11-232D9.3
RP11-232D9.3
chr4_-_186877481 0.465 ENST00000444781.1
ENST00000432655.1
SORBS2

sorbin and SH3 domain containing 2

chr10_-_112678976 0.462 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr10_-_99030395 0.455 ENST00000355366.5
ENST00000371027.1
ARHGAP19

Rho GTPase activating protein 19

chr6_-_165989936 0.454 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr11_-_111649074 0.453 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr1_+_219347203 0.450 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr10_+_35484793 0.447 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr8_-_95449155 0.445 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr1_+_219347186 0.426 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr20_-_2644832 0.420 ENST00000380851.5
ENST00000380843.4
IDH3B

isocitrate dehydrogenase 3 (NAD+) beta

chr15_+_79166065 0.413 ENST00000559690.1
ENST00000559158.1
MORF4L1

mortality factor 4 like 1

chr2_+_192543153 0.410 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr12_-_56727487 0.407 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr11_-_111649015 0.403 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr3_-_141747439 0.395 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr7_+_134576151 0.393 ENST00000393118.2
CALD1
caldesmon 1
chr16_-_30596818 0.390 ENST00000567773.1
ZNF785
zinc finger protein 785
chr1_-_21113105 0.385 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3




heterochromatin protein 1, binding protein 3




chr7_-_102985288 0.383 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr7_-_120498357 0.370 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chrX_-_69509738 0.368 ENST00000374454.1
ENST00000239666.4
PDZD11

PDZ domain containing 11

chr7_+_132937820 0.355 ENST00000393161.2
ENST00000253861.4
EXOC4

exocyst complex component 4

chr6_+_134758827 0.353 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr14_-_23755297 0.350 ENST00000357460.5
HOMEZ
homeobox and leucine zipper encoding
chr6_+_26199737 0.350 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr8_-_74659693 0.336 ENST00000518767.1
STAU2
staufen double-stranded RNA binding protein 2
chr4_-_69434245 0.332 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr12_+_117013656 0.331 ENST00000556529.1
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr11_+_19798964 0.331 ENST00000527559.2
NAV2
neuron navigator 2
chr4_+_25915896 0.330 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr12_-_51418549 0.326 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_-_220110187 0.322 ENST00000295759.7
ENST00000392089.2
GLB1L

galactosidase, beta 1-like

chr6_+_111303218 0.308 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr1_-_110283138 0.308 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr12_+_54674482 0.308 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1




heterogeneous nuclear ribonucleoprotein A1




chr21_+_45725050 0.302 ENST00000403390.1
PFKL
phosphofructokinase, liver
chr4_-_47465666 0.300 ENST00000381571.4
COMMD8
COMM domain containing 8
chr22_-_36761081 0.299 ENST00000456729.1
ENST00000401701.1
MYH9

myosin, heavy chain 9, non-muscle

chr14_+_31028329 0.292 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr2_-_220110111 0.292 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr19_-_7553852 0.291 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr19_-_7553889 0.289 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr6_-_31940065 0.282 ENST00000375349.3
ENST00000337523.5
DXO

decapping exoribonuclease

chr17_-_62493131 0.281 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr17_-_38083092 0.280 ENST00000394169.1
ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_-_99952769 0.279 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
TXNDC9


thioredoxin domain containing 9


chr8_+_11666649 0.279 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr6_+_27114861 0.278 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr4_-_186682716 0.278 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chrX_+_70752917 0.272 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr14_-_65289812 0.270 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB


spectrin, beta, erythrocytic


chr14_+_50999744 0.264 ENST00000441560.2
ATL1
atlastin GTPase 1
chr5_+_173316341 0.255 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr4_+_25915822 0.251 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr20_-_43133491 0.249 ENST00000411544.1
SERINC3
serine incorporator 3
chr13_-_88463487 0.244 ENST00000606221.1
RP11-471M2.3
RP11-471M2.3
chr17_+_42925270 0.243 ENST00000253410.2
ENST00000587021.1
HIGD1B

HIG1 hypoxia inducible domain family, member 1B

chr1_+_151043070 0.243 ENST00000368918.3
ENST00000368917.1
GABPB2

GA binding protein transcription factor, beta subunit 2

chr2_+_128848740 0.242 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_204193101 0.242 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2


abl-interactor 2


chrX_-_30877837 0.240 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chrX_+_70752945 0.240 ENST00000373701.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_127782787 0.238 ENST00000564121.1
RP11-521O16.2
RP11-521O16.2
chr10_+_75936444 0.238 ENST00000372734.3
ENST00000541550.1
ADK

adenosine kinase

chr6_-_26199499 0.235 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr6_-_8102714 0.234 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1



eukaryotic translation elongation factor 1 epsilon 1



chr14_-_50999307 0.233 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr12_-_57113333 0.232 ENST00000550920.1
NACA
nascent polypeptide-associated complex alpha subunit
chr19_+_57019212 0.232 ENST00000308031.5
ENST00000591537.1
ZNF471

zinc finger protein 471

chr6_+_138725343 0.231 ENST00000607197.1
ENST00000367697.3
HEBP2

heme binding protein 2

chrX_-_72347916 0.229 ENST00000373518.1
NAP1L6
nucleosome assembly protein 1-like 6
chr7_+_128379449 0.229 ENST00000479257.1
CALU
calumenin
chr3_-_12587055 0.227 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr7_+_134576317 0.223 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr22_-_37880543 0.222 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_204193149 0.217 ENST00000422511.2
ABI2
abl-interactor 2
chr17_-_56609302 0.213 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4





septin 4





chr6_+_88117683 0.212 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr15_+_42131011 0.211 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr10_+_89419370 0.209 ENST00000361175.4
ENST00000456849.1
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr14_+_37641012 0.206 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr17_-_72772425 0.204 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr14_-_45431091 0.202 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28


kelch-like family member 28


chr14_+_32030582 0.200 ENST00000550649.1
ENST00000281081.7
NUBPL

nucleotide binding protein-like

chr17_-_56494882 0.200 ENST00000584437.1
RNF43
ring finger protein 43
chr11_-_82681626 0.199 ENST00000534396.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr14_+_56078695 0.194 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr18_-_19283649 0.191 ENST00000584464.1
ENST00000578270.1
ABHD3

abhydrolase domain containing 3

chr19_-_35992780 0.190 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr3_-_126327398 0.189 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr9_+_128510454 0.187 ENST00000491787.3
ENST00000447726.2
PBX3

pre-B-cell leukemia homeobox 3

chr8_-_101734170 0.185 ENST00000522387.1
ENST00000518196.1
PABPC1

poly(A) binding protein, cytoplasmic 1

chr14_-_89878369 0.183 ENST00000553840.1
ENST00000556916.1
FOXN3

forkhead box N3

chr19_+_41903709 0.182 ENST00000542943.1
ENST00000457836.2
BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr19_+_4769117 0.181 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3HG








MIR7-3 host gene (non-protein coding)








chr17_+_3572087 0.180 ENST00000248378.5
ENST00000397133.2
EMC6

ER membrane protein complex subunit 6

chr10_+_121578211 0.175 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr1_+_196743943 0.172 ENST00000471440.2
ENST00000391985.3
CFHR3

complement factor H-related 3

chr2_-_86948245 0.162 ENST00000439940.2
ENST00000604011.1
CHMP3
RNF103-CHMP3
charged multivesicular body protein 3
RNF103-CHMP3 readthrough
chr8_+_107738240 0.158 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr14_+_78227105 0.157 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178



chromosome 14 open reading frame 178



chr17_+_41177220 0.154 ENST00000587250.2
ENST00000544533.1
RND2

Rho family GTPase 2

chr1_+_104104379 0.153 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr5_-_1799864 0.153 ENST00000510999.1
MRPL36
mitochondrial ribosomal protein L36
chr11_+_10772534 0.151 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr7_+_95115210 0.150 ENST00000428113.1
ENST00000325885.5
ASB4

ankyrin repeat and SOCS box containing 4

chr6_+_30585486 0.150 ENST00000259873.4
ENST00000506373.2
MRPS18B

mitochondrial ribosomal protein S18B

chr10_+_124913793 0.150 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3


BUB3 mitotic checkpoint protein


chr8_-_95220775 0.146 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr20_+_61584026 0.143 ENST00000370351.4
ENST00000370349.3
SLC17A9

solute carrier family 17 (vesicular nucleotide transporter), member 9

chr11_+_13690200 0.142 ENST00000354817.3
FAR1
fatty acyl CoA reductase 1
chr1_-_203274418 0.141 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr1_+_45212051 0.141 ENST00000372222.3
KIF2C
kinesin family member 2C
chr17_-_56494908 0.140 ENST00000577716.1
RNF43
ring finger protein 43
chr21_-_46340884 0.140 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr7_-_116607526 0.139 ENST00000420664.1
AC106873.4
Uncharacterized protein
chr2_-_86116020 0.139 ENST00000525834.2
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_33049690 0.139 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chr16_-_71843047 0.137 ENST00000299980.4
ENST00000393512.3
AP1G1

adaptor-related protein complex 1, gamma 1 subunit

chr1_+_87595497 0.136 ENST00000471417.1
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr17_+_20483037 0.135 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr8_-_116504448 0.135 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr13_-_67802549 0.131 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr7_+_102191679 0.129 ENST00000507918.1
ENST00000432940.1
SPDYE2

speedy/RINGO cell cycle regulator family member E2

chr2_-_228497888 0.128 ENST00000264387.4
ENST00000409066.1
C2orf83

chromosome 2 open reading frame 83

chr7_-_47579188 0.122 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3



tensin 3



chr1_+_89246647 0.120 ENST00000544045.1
PKN2
protein kinase N2
chr9_-_123555655 0.120 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2


F-box and WD repeat domain containing 2


chr10_+_124320195 0.119 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr2_+_204193129 0.119 ENST00000417864.1
ABI2
abl-interactor 2
chr8_+_30244580 0.118 ENST00000523115.1
ENST00000519647.1
RBPMS

RNA binding protein with multiple splicing

chr3_-_45837959 0.117 ENST00000353278.4
ENST00000456124.2
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr6_-_86303833 0.117 ENST00000505648.1
SNX14
sorting nexin 14
chr10_-_5046042 0.117 ENST00000421196.3
ENST00000455190.1
AKR1C2

aldo-keto reductase family 1, member C2

chr16_+_29127282 0.117 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr18_-_32870148 0.116 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30





RP11-158H5.7
zinc finger and SCAN domain containing 30





RP11-158H5.7
chr1_+_24286287 0.116 ENST00000334351.7
ENST00000374468.1
PNRC2

proline-rich nuclear receptor coactivator 2

chr8_-_27630102 0.115 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
CCDC25


coiled-coil domain containing 25


chr9_+_139377947 0.114 ENST00000354376.1
C9orf163
chromosome 9 open reading frame 163
chr17_+_6544078 0.109 ENST00000250101.5
TXNDC17
thioredoxin domain containing 17
chr1_-_6240183 0.108 ENST00000262450.3
ENST00000378021.1
CHD5

chromodomain helicase DNA binding protein 5

chr8_-_8046331 0.107 ENST00000594215.1
LRLE1
Liver-related low express protein 1; Uncharacterized protein
chr2_-_100925967 0.105 ENST00000409647.1
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr14_+_21458127 0.105 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17





methyltransferase like 17





chr2_+_220110177 0.103 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16


serine/threonine kinase 16



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.7 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 1.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:0051414 response to cortisol(GO:0051414)
0.1 2.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.9 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.6 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 7.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.3 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 1.8 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 1.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 1.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.4 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.5 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.4 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 1.2 GO:0070125 mitochondrial translational elongation(GO:0070125)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031251 PAN complex(GO:0031251)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.7 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.7 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 1.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 1.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 6.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 2.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.9 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_ATM_PATHWAY ATM pathway
0.0 1.1 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.5 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 3.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 1.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.8 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle