Motif ID: HES1

Z-value: 0.634


Transcription factors associated with HES1:

Gene SymbolEntrez IDGene Name
HES1 ENSG00000114315.3 HES1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.363.4e-01Click!


Activity profile for motif HES1.

activity profile for motif HES1


Sorted Z-values histogram for motif HES1

Sorted Z-values for motif HES1



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_78492927 0.544 ENST00000334286.5
EDNRB
endothelin receptor type B
chr13_-_78492955 0.401 ENST00000446573.1
EDNRB
endothelin receptor type B
chr1_+_23037323 0.384 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2



EPH receptor B2



chr7_-_155089251 0.282 ENST00000609974.1
AC144652.1
AC144652.1
chr17_+_78075361 0.282 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr9_+_91926103 0.270 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr18_+_48086440 0.256 ENST00000400384.2
ENST00000540640.1
ENST00000592595.1
MAPK4


mitogen-activated protein kinase 4


chr9_+_101867387 0.253 ENST00000374990.2
ENST00000552516.1
TGFBR1

transforming growth factor, beta receptor 1

chr2_+_178077477 0.238 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr13_-_21099935 0.236 ENST00000298248.7
ENST00000382812.1
CRYL1

crystallin, lambda 1

chr1_+_6845578 0.234 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr3_-_179169181 0.222 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr1_+_110198689 0.219 ENST00000369836.4
GSTM4
glutathione S-transferase mu 4
chr3_-_52001448 0.216 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4





poly(rC) binding protein 4





chrX_-_109561294 0.214 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr17_+_78075324 0.214 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr1_+_6845497 0.214 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr9_+_101867359 0.211 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr17_+_78075498 0.206 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr22_-_39151434 0.206 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr8_-_142318398 0.203 ENST00000520137.1
SLC45A4
solute carrier family 45, member 4
chr17_-_80656528 0.202 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B


RAB40B, member RAS oncogene family


chrX_+_152907913 0.200 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr15_-_90645679 0.197 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr2_+_204192942 0.195 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr22_-_39151463 0.193 ENST00000405510.1
ENST00000433561.1
SUN2

Sad1 and UNC84 domain containing 2

chr11_-_67981295 0.184 ENST00000405515.1
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr1_-_19283163 0.183 ENST00000455833.2
IFFO2
intermediate filament family orphan 2
chr7_+_116312411 0.182 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET


met proto-oncogene


chr1_+_53793885 0.180 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr1_+_110198714 0.180 ENST00000336075.5
ENST00000326729.5
GSTM4

glutathione S-transferase mu 4

chr14_-_100070363 0.179 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr10_+_120789223 0.178 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chrX_-_131623982 0.172 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr9_+_4490394 0.171 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr22_-_39151995 0.171 ENST00000405018.1
ENST00000438058.1
SUN2

Sad1 and UNC84 domain containing 2

chr15_-_58357932 0.167 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr19_+_2977444 0.167 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6



transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)



chr2_-_96811170 0.167 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr1_+_153950202 0.163 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr1_+_110198944 0.162 ENST00000369833.1
GSTM4
glutathione S-transferase mu 4
chr10_-_123357598 0.161 ENST00000358487.5
ENST00000369058.3
ENST00000369060.4
ENST00000359354.2
FGFR2



fibroblast growth factor receptor 2



chr16_-_89556942 0.160 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr10_-_105615164 0.160 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chr18_+_33767473 0.158 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr18_-_77793891 0.156 ENST00000592957.1
ENST00000585474.1
TXNL4A

thioredoxin-like 4A

chr6_-_74233480 0.154 ENST00000455918.1
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr19_-_55919087 0.153 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S


ubiquitin-conjugating enzyme E2S


chr22_-_39151947 0.152 ENST00000216064.4
SUN2
Sad1 and UNC84 domain containing 2
chr7_+_130131907 0.152 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chr16_+_2039946 0.152 ENST00000248121.2
ENST00000568896.1
SYNGR3

synaptogyrin 3

chr1_+_210502238 0.145 ENST00000545154.1
ENST00000537898.1
ENST00000391905.3
ENST00000545781.1
ENST00000261458.3
ENST00000308852.6
HHAT





hedgehog acyltransferase





chr9_-_72374848 0.145 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1


protein prenyltransferase alpha subunit repeat containing 1


chr10_+_49514698 0.144 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8


mitogen-activated protein kinase 8


chr13_+_98795664 0.144 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_-_98030360 0.143 ENST00000005260.8
BAIAP2L1
BAI1-associated protein 2-like 1
chr17_-_78450398 0.141 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr10_-_105421427 0.141 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr8_+_120885949 0.141 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr15_-_58357866 0.140 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr22_-_39150947 0.139 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2



Sad1 and UNC84 domain containing 2



chr3_-_13009168 0.139 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr2_+_201390843 0.137 ENST00000357799.4
ENST00000409203.3
SGOL2

shugoshin-like 2 (S. pombe)

chr12_+_57610562 0.136 ENST00000349394.5
NXPH4
neurexophilin 4
chr19_+_11670245 0.136 ENST00000585493.1
ZNF627
zinc finger protein 627
chrX_-_106960285 0.136 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr2_-_200715573 0.135 ENST00000420922.2
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr19_+_54960790 0.135 ENST00000443957.1
LENG8
leukocyte receptor cluster (LRC) member 8
chr9_-_3525968 0.131 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr12_+_96588368 0.130 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr16_-_54963026 0.130 ENST00000560208.1
ENST00000557792.1
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr4_+_183065793 0.129 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr2_+_192542850 0.129 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr2_-_224702270 0.129 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr20_-_3154162 0.128 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr12_-_76478686 0.128 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chrX_-_131623874 0.128 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr19_+_54960358 0.127 ENST00000439657.1
ENST00000376514.2
ENST00000376526.4
ENST00000436479.1
LENG8



leukocyte receptor cluster (LRC) member 8



chr12_+_50355647 0.125 ENST00000293599.6
AQP5
aquaporin 5
chr5_-_159797627 0.124 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr10_-_123357910 0.124 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2





fibroblast growth factor receptor 2





chr2_+_204193149 0.124 ENST00000422511.2
ABI2
abl-interactor 2
chr1_-_98386543 0.123 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
DPYD


dihydropyrimidine dehydrogenase


chr3_-_179169330 0.123 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_+_145734433 0.122 ENST00000301327.4
MFSD3
major facilitator superfamily domain containing 3
chr12_+_96588279 0.121 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr1_+_64936428 0.118 ENST00000371073.2
ENST00000290039.5
CACHD1

cache domain containing 1

chr10_-_90751038 0.117 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr15_+_79165372 0.117 ENST00000558502.1
MORF4L1
mortality factor 4 like 1
chr1_-_32801825 0.117 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr2_-_224702201 0.115 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr12_+_133707161 0.115 ENST00000538918.1
ENST00000540609.1
ENST00000248211.6
ENST00000543271.1
ENST00000536877.1
ZNF10




zinc finger protein 10




chr9_+_133971909 0.114 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L



allograft inflammatory factor 1-like



chr17_-_8279977 0.113 ENST00000396267.1
KRBA2
KRAB-A domain containing 2
chr10_+_74033672 0.113 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr2_+_204193129 0.112 ENST00000417864.1
ABI2
abl-interactor 2
chr15_+_79165296 0.112 ENST00000558746.1
ENST00000558830.1
ENST00000559345.1
MORF4L1


mortality factor 4 like 1


chr3_+_184081137 0.111 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr1_+_118472343 0.109 ENST00000369441.3
ENST00000349139.5
WDR3

WD repeat domain 3

chr8_+_26240414 0.109 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr6_-_105585022 0.109 ENST00000314641.5
BVES
blood vessel epicardial substance
chr19_+_10541462 0.109 ENST00000293683.5
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_59066327 0.109 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
CHMP2A


charged multivesicular body protein 2A


chr7_+_130126165 0.106 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr18_-_51750948 0.106 ENST00000583046.1
ENST00000398398.2
MBD2

methyl-CpG binding domain protein 2

chr10_-_104001231 0.106 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr12_-_117537240 0.106 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC


tescalcin


chr3_-_47823298 0.106 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr3_+_133292574 0.106 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr2_+_181845763 0.105 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr20_-_43280325 0.103 ENST00000537820.1
ADA
adenosine deaminase
chr7_-_74867509 0.103 ENST00000426327.3
GATSL2
GATS protein-like 2
chr20_-_31124186 0.102 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr17_+_54671047 0.102 ENST00000332822.4
NOG
noggin
chr12_-_125348448 0.101 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr20_-_35492048 0.101 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr3_+_184081175 0.101 ENST00000452961.1
ENST00000296223.3
POLR2H

polymerase (RNA) II (DNA directed) polypeptide H

chr17_+_44668387 0.101 ENST00000576040.1
NSF
N-ethylmaleimide-sensitive factor
chr20_-_57607347 0.101 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
ATP5E


ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit


chr2_+_204193101 0.100 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2


abl-interactor 2


chr9_-_139948487 0.100 ENST00000355097.2
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr15_-_66084621 0.100 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr13_-_31039375 0.098 ENST00000399494.1
HMGB1
high mobility group box 1
chr16_-_54962704 0.098 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
CRNDE


colorectal neoplasia differentially expressed (non-protein coding)


chr2_+_192543153 0.098 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr6_-_74230741 0.098 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr9_+_133971863 0.098 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chr12_-_125348329 0.097 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1




scavenger receptor class B, member 1




chr1_+_94883991 0.097 ENST00000370214.4
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr9_+_134378289 0.097 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1












protein-O-mannosyltransferase 1












chr10_-_62493223 0.097 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_67999999 0.097 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr6_+_11537910 0.096 ENST00000543875.1
TMEM170B
transmembrane protein 170B
chr1_+_94883931 0.096 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3


ATP-binding cassette, sub-family D (ALD), member 3


chr17_+_29815113 0.096 ENST00000583755.1
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chrX_+_21959108 0.096 ENST00000457085.1
SMS
spermine synthase
chr11_-_615570 0.095 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7


interferon regulatory factor 7


chr6_-_13711773 0.094 ENST00000011619.3
RANBP9
RAN binding protein 9
chr2_+_120124497 0.094 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
DBI




diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)




chr1_+_46152886 0.094 ENST00000372025.4
TMEM69
transmembrane protein 69
chr1_+_94884023 0.093 ENST00000315713.5
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr10_-_104474128 0.093 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr22_+_50247449 0.093 ENST00000216268.5
ZBED4
zinc finger, BED-type containing 4
chr5_-_68664989 0.092 ENST00000508954.1
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr17_-_57184260 0.092 ENST00000376149.3
ENST00000393066.3
TRIM37

tripartite motif containing 37

chr15_+_79165112 0.091 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr1_+_227127981 0.091 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr3_+_54156664 0.090 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr19_-_59066452 0.090 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr3_+_23851928 0.089 ENST00000467766.1
ENST00000424381.1
UBE2E1

ubiquitin-conjugating enzyme E2E 1

chr15_+_79165151 0.088 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr2_-_26467557 0.088 ENST00000380649.3
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr4_-_2264015 0.088 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr1_+_225965518 0.087 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
SRP9


signal recognition particle 9kDa


chr2_-_26467465 0.087 ENST00000457468.2
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr1_-_167522982 0.086 ENST00000370509.4
CREG1
cellular repressor of E1A-stimulated genes 1
chr19_+_49622646 0.086 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chrX_-_106243294 0.086 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr12_+_72080253 0.086 ENST00000549735.1
TMEM19
transmembrane protein 19
chr2_+_192542879 0.086 ENST00000409510.1
NABP1
nucleic acid binding protein 1
chr17_+_29718642 0.085 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr3_-_148804275 0.085 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr14_-_91526462 0.084 ENST00000536315.2
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr3_-_11761068 0.084 ENST00000418000.1
ENST00000417206.2
VGLL4

vestigial like 4 (Drosophila)

chr5_+_70196805 0.083 ENST00000507348.1
ENST00000512868.2
ENST00000512649.1
SERF1A


small EDRK-rich factor 1A (telomeric)


chr19_+_49617581 0.083 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr2_-_62733476 0.083 ENST00000335390.5
TMEM17
transmembrane protein 17
chr17_+_28256874 0.083 ENST00000541045.1
ENST00000536908.2
EFCAB5

EF-hand calcium binding domain 5

chr7_-_32931387 0.083 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr7_-_32931623 0.083 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr3_+_184081213 0.083 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_27237615 0.083 ENST00000458529.1
ENST00000402218.1
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr19_-_3869012 0.083 ENST00000592398.1
ENST00000262961.4
ENST00000439086.2
ZFR2


zinc finger RNA binding protein 2


chr7_-_130597935 0.082 ENST00000447307.1
ENST00000418546.1
MIR29B1

microRNA 29a

chr16_-_54962415 0.082 ENST00000501177.3
ENST00000559598.2
CRNDE

colorectal neoplasia differentially expressed (non-protein coding)

chr15_-_44069741 0.082 ENST00000319359.3
ELL3
elongation factor RNA polymerase II-like 3
chr3_-_127541679 0.082 ENST00000265052.5
MGLL
monoglyceride lipase
chr2_-_224702740 0.081 ENST00000444408.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr9_-_4741217 0.081 ENST00000447596.4
AK3
adenylate kinase 3
chr10_-_119134918 0.081 ENST00000334464.5
PDZD8
PDZ domain containing 8
chr15_+_79165222 0.081 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr19_+_34891252 0.080 ENST00000606020.1
RP11-618P17.4
Uncharacterized protein
chr9_+_133320301 0.080 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr3_+_183415558 0.080 ENST00000305135.5
YEATS2
YEATS domain containing 2
chr19_-_7936344 0.080 ENST00000599142.1
CTD-3193O13.9
Protein FLJ22184
chr12_-_46662772 0.080 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
SLC38A1


solute carrier family 38, member 1


chr22_-_25801333 0.079 ENST00000444995.3
LRP5L
low density lipoprotein receptor-related protein 5-like
chr1_+_6845384 0.079 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr17_-_28257080 0.078 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2




slingshot protein phosphatase 2




chr3_+_54156570 0.078 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr15_-_32162833 0.078 ENST00000560598.1
OTUD7A
OTU domain containing 7A
chr20_+_31407692 0.078 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr4_+_26321284 0.078 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ



recombination signal binding protein for immunoglobulin kappa J region



chr12_+_77158021 0.077 ENST00000550876.1
ZDHHC17
zinc finger, DHHC-type containing 17
chr15_-_66084428 0.077 ENST00000443035.3
ENST00000431932.2
DENND4A

DENN/MADD domain containing 4A

chr11_-_46867780 0.077 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5


cytoskeleton associated protein 5


chr19_+_30433372 0.077 ENST00000312051.6
URI1
URI1, prefoldin-like chaperone
chr18_+_12947981 0.077 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr5_+_70196492 0.077 ENST00000317633.9
ENST00000511162.1
ENST00000354833.3
ENST00000513436.2
ENST00000504458.1
SERF1A




small EDRK-rich factor 1A (telomeric)




chr3_-_48885228 0.076 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
PRKAR2A



protein kinase, cAMP-dependent, regulatory, type II, alpha




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0007497 posterior midgut development(GO:0007497) positive regulation of penile erection(GO:0060406) endothelin receptor signaling pathway(GO:0086100)
0.2 0.7 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.3 GO:0060648 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) mammary gland bud morphogenesis(GO:0060648) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.5 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.6 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.1 GO:0060405 regulation of penile erection(GO:0060405)
0.1 0.2 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.2 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:2000110 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.0 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.0 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.0 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.0 GO:0060926 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0002461 tolerance induction dependent upon immune response(GO:0002461) regulation of thymocyte migration(GO:2000410)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.0 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629) extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.0 GO:0097431 mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 0.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.2 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.6 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.0 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport