Motif ID: HDX

Z-value: 0.207


Transcription factors associated with HDX:

Gene SymbolEntrez IDGene Name
HDX ENSG00000165259.9 HDX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HDXhg19_v2_chrX_-_83757399_837574870.373.3e-01Click!


Activity profile for motif HDX.

activity profile for motif HDX


Sorted Z-values histogram for motif HDX

Sorted Z-values for motif HDX



Network of associatons between targets according to the STRING database.



First level regulatory network of HDX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_165555200 0.660 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr11_-_66675371 0.159 ENST00000393955.2
PC
pyruvate carboxylase
chr3_+_54157480 0.144 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr1_-_153363452 0.142 ENST00000368732.1
ENST00000368733.3
S100A8

S100 calcium binding protein A8

chr12_+_123849462 0.120 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr1_+_197237352 0.116 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1


crumbs homolog 1 (Drosophila)


chr1_+_47489240 0.094 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr14_+_71788096 0.057 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr11_+_9685604 0.038 ENST00000447399.2
ENST00000318950.6
SWAP70

SWAP switching B-cell complex 70kDa subunit

chr22_+_40440804 0.036 ENST00000441751.1
ENST00000301923.9
TNRC6B

trinucleotide repeat containing 6B

chr5_+_140625147 0.036 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr5_-_135290651 0.033 ENST00000522943.1
ENST00000514447.2
LECT2

leukocyte cell-derived chemotaxin 2

chr3_+_107241882 0.026 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chrX_+_100224676 0.019 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr5_-_35230434 0.019 ENST00000504500.1
PRLR
prolactin receptor
chr22_+_45714672 0.017 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr10_-_14372870 0.016 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr2_+_113735575 0.015 ENST00000376489.2
ENST00000259205.4
IL36G

interleukin 36, gamma

chr7_+_99954224 0.015 ENST00000608825.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr19_-_58485895 0.014 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr7_+_144015218 0.013 ENST00000408951.1
OR2A1
olfactory receptor, family 2, subfamily A, member 1
chr7_-_135412925 0.012 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr12_+_101869096 0.011 ENST00000551346.1
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr12_+_10460417 0.010 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1


killer cell lectin-like receptor subfamily D, member 1


chr19_-_41934635 0.010 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr12_+_10460549 0.010 ENST00000543420.1
ENST00000543777.1
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr5_+_140165876 0.009 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr19_+_36602104 0.009 ENST00000585332.1
ENST00000262637.4
OVOL3

ovo-like zinc finger 3

chr18_+_29027696 0.006 ENST00000257189.4
DSG3
desmoglein 3
chr1_+_21880560 0.005 ENST00000425315.2
ALPL
alkaline phosphatase, liver/bone/kidney
chr12_-_39734783 0.005 ENST00000552961.1
KIF21A
kinesin family member 21A
chr1_+_75600567 0.004 ENST00000356261.3
LHX8
LIM homeobox 8
chrX_+_55649833 0.004 ENST00000339140.3
FOXR2
forkhead box R2
chrX_+_27608490 0.004 ENST00000451261.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr5_-_35230649 0.003 ENST00000382002.5
PRLR
prolactin receptor
chr1_+_84630053 0.001 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr5_-_35230771 0.000 ENST00000342362.5
PRLR
prolactin receptor
chrX_+_27608517 0.000 ENST00000431122.2
DCAF8L2
DDB1 and CUL4 associated factor 8-like 2
chr5_-_35230569 0.000 ENST00000515839.1
PRLR
prolactin receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin