Motif ID: HAND1

Z-value: 0.567


Transcription factors associated with HAND1:

Gene SymbolEntrez IDGene Name
HAND1 ENSG00000113196.2 HAND1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HAND1hg19_v2_chr5_-_153857819_153857824-0.511.7e-01Click!


Activity profile for motif HAND1.

activity profile for motif HAND1


Sorted Z-values histogram for motif HAND1

Sorted Z-values for motif HAND1



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_87804815 1.507 ENST00000369582.2
 CGA
glycoprotein hormones, alpha polypeptide
chr19_+_36359341 1.384 ENST00000221891.4
 APLP1
amyloid beta (A4) precursor-like protein 1
chr22_+_24999114 0.414 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
 GGT1










gamma-glutamyltransferase 1










chr22_+_31518938 0.389 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J






inositol polyphosphate-5-phosphatase J






chr4_+_41614909 0.376 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
 LIMCH1


LIM and calponin homology domains 1


chrX_-_133930285 0.348 ENST00000486347.1
ENST00000343004.5
 FAM122B

family with sequence similarity 122B

chr3_-_15382875 0.340 ENST00000408919.3
 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr19_+_47421933 0.251 ENST00000404338.3
 ARHGAP35
Rho GTPase activating protein 35
chr17_+_6347729 0.244 ENST00000572447.1
 FAM64A
family with sequence similarity 64, member A
chr1_+_164528866 0.241 ENST00000420696.2
 PBX1
pre-B-cell leukemia homeobox 1
chr10_+_99344071 0.240 ENST00000370647.4
ENST00000370646.4
 HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr22_+_25003626 0.231 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
 GGT1


gamma-glutamyltransferase 1


chr20_-_56285595 0.213 ENST00000395816.3
ENST00000347215.4
 PMEPA1

prostate transmembrane protein, androgen induced 1

chr20_-_56286479 0.213 ENST00000265626.4
 PMEPA1
prostate transmembrane protein, androgen induced 1
chr4_+_41614720 0.210 ENST00000509277.1
 LIMCH1
LIM and calponin homology domains 1
chr1_-_155904187 0.209 ENST00000368321.3
ENST00000368320.3
 KIAA0907

KIAA0907

chr17_+_6347761 0.206 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
 FAM64A




family with sequence similarity 64, member A




chr12_-_57630873 0.195 ENST00000556732.1
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr2_-_25475120 0.191 ENST00000380746.4
ENST00000402667.1
 DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chrX_+_149531524 0.188 ENST00000370401.2
 MAMLD1
mastermind-like domain containing 1
chr5_-_41870621 0.188 ENST00000196371.5
 OXCT1
3-oxoacid CoA transferase 1
chr9_+_35805527 0.182 ENST00000421267.1
 NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr1_+_28261533 0.180 ENST00000411604.1
ENST00000373888.4
 SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr11_+_101785727 0.175 ENST00000263468.8
 KIAA1377
KIAA1377
chr14_-_74892805 0.173 ENST00000331628.3
ENST00000554953.1
 SYNDIG1L

synapse differentiation inducing 1-like

chr11_-_62477313 0.168 ENST00000464544.1
ENST00000530009.1
 BSCL2

Berardinelli-Seip congenital lipodystrophy 2 (seipin)

chr2_-_197791441 0.167 ENST00000409475.1
ENST00000354764.4
ENST00000374738.3
 PGAP1


post-GPI attachment to proteins 1


chr6_-_133119668 0.159 ENST00000275227.4
ENST00000538764.1
 SLC18B1

solute carrier family 18, subfamily B, member 1

chr1_+_65775204 0.157 ENST00000371069.4
 DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chrX_+_149531606 0.149 ENST00000432680.2
 MAMLD1
mastermind-like domain containing 1
chr4_+_22999152 0.145 ENST00000511453.1
 RP11-412P11.1
RP11-412P11.1
chr16_+_56969284 0.143 ENST00000568358.1
 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_-_155904161 0.138 ENST00000368319.3
 KIAA0907
KIAA0907
chr11_+_124933191 0.128 ENST00000532000.1
ENST00000308074.4
 SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr1_+_28261492 0.127 ENST00000373894.3
 SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr11_+_124932986 0.126 ENST00000407458.1
ENST00000298280.5
 SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr1_+_215747118 0.120 ENST00000448333.1
 KCTD3
potassium channel tetramerization domain containing 3
chr16_-_28621298 0.115 ENST00000566189.1
 SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_-_52344416 0.113 ENST00000544028.1
 NRD1
nardilysin (N-arginine dibasic convertase)
chr2_+_201997492 0.113 ENST00000494258.1
 CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_-_42588338 0.111 ENST00000234301.2
 COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr22_+_25003606 0.107 ENST00000432867.1
 GGT1
gamma-glutamyltransferase 1
chr12_+_49717019 0.105 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
 TROAP







trophinin associated protein







chr16_-_28621312 0.103 ENST00000314752.7
 SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr2_+_98262497 0.102 ENST00000258424.2
 COX5B
cytochrome c oxidase subunit Vb
chr6_+_80341000 0.102 ENST00000369838.4
 SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr1_-_33777822 0.102 ENST00000330379.5
 A3GALT2
alpha 1,3-galactosyltransferase 2
chr10_-_99393242 0.100 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
 MORN4


MORN repeat containing 4


chr1_-_52344471 0.096 ENST00000352171.7
ENST00000354831.7
 NRD1

nardilysin (N-arginine dibasic convertase)

chr1_-_32210275 0.095 ENST00000440175.2
 BAI2
brain-specific angiogenesis inhibitor 2
chr18_+_12407895 0.095 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
 SLMO1



slowmo homolog 1 (Drosophila)



chr2_+_228678550 0.095 ENST00000409189.3
ENST00000358813.4
 CCL20

chemokine (C-C motif) ligand 20

chr6_-_117923610 0.094 ENST00000535237.1
ENST00000052569.6
 GOPC

golgi-associated PDZ and coiled-coil motif containing

chr22_+_25003568 0.092 ENST00000447416.1
 GGT1
gamma-glutamyltransferase 1
chr13_-_30881134 0.091 ENST00000380617.3
ENST00000441394.1
 KATNAL1

katanin p60 subunit A-like 1

chr11_+_124932955 0.091 ENST00000403796.2
 SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr3_-_20227720 0.087 ENST00000412997.1
 SGOL1
shugoshin-like 1 (S. pombe)
chr11_+_118826999 0.087 ENST00000264031.2
 UPK2
uroplakin 2
chr6_-_39282221 0.086 ENST00000453413.2
 KCNK17
potassium channel, subfamily K, member 17
chr6_+_6588902 0.085 ENST00000230568.4
 LY86
lymphocyte antigen 86
chr1_-_214638146 0.085 ENST00000543945.1
 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_+_99344104 0.085 ENST00000555577.1
ENST00000370649.3
 PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr16_-_28621353 0.083 ENST00000567512.1
 SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_28261621 0.081 ENST00000549094.1
 SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr12_-_7261772 0.081 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
 C1RL




complement component 1, r subcomponent-like




chr20_+_3713314 0.078 ENST00000254963.2
ENST00000542646.1
ENST00000399701.1
 HSPA12B


heat shock 70kD protein 12B


chr11_-_62477103 0.078 ENST00000532818.1
 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_202091980 0.077 ENST00000367282.5
 GPR37L1
G protein-coupled receptor 37 like 1
chr1_+_174846570 0.076 ENST00000392064.2
 RABGAP1L
RAB GTPase activating protein 1-like
chr1_-_223988426 0.076 ENST00000391879.2
 TP53BP2
tumor protein p53 binding protein, 2
chr10_-_104211294 0.076 ENST00000239125.1
 C10orf95
chromosome 10 open reading frame 95
chr3_+_141103634 0.075 ENST00000507722.1
 ZBTB38
zinc finger and BTB domain containing 38
chr4_+_25162253 0.071 ENST00000512921.1
 PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr15_-_79576156 0.070 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
 RP11-17L5.4





RP11-17L5.4





chr12_+_53848505 0.070 ENST00000552819.1
ENST00000455667.3
 PCBP2

poly(rC) binding protein 2

chr14_-_53331239 0.070 ENST00000553663.1
 FERMT2
fermitin family member 2
chr10_-_99393208 0.069 ENST00000307450.6
 MORN4
MORN repeat containing 4
chr15_+_74509530 0.069 ENST00000321288.5
 CCDC33
coiled-coil domain containing 33
chr2_+_201997595 0.068 ENST00000470178.2
 CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_-_10652993 0.068 ENST00000536829.1
 EMP2
epithelial membrane protein 2
chr12_+_53848549 0.067 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
 PCBP2


poly(rC) binding protein 2


chr12_+_68042495 0.067 ENST00000344096.3
 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr1_+_52870227 0.066 ENST00000257181.9
 PRPF38A
pre-mRNA processing factor 38A
chr4_+_76481258 0.066 ENST00000311623.4
ENST00000435974.2
 C4orf26

chromosome 4 open reading frame 26

chr20_+_34020827 0.063 ENST00000374375.1
 GDF5OS
growth differentiation factor 5 opposite strand
chr4_-_25162188 0.062 ENST00000302922.3
 SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr4_-_40631859 0.058 ENST00000295971.7
ENST00000319592.4
 RBM47

RNA binding motif protein 47

chr18_+_55712915 0.057 ENST00000592846.1
 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr7_-_142583506 0.056 ENST00000359396.3
 TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr6_-_112194484 0.055 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
 FYN






FYN oncogene related to SRC, FGR, YES






chr2_-_228582709 0.055 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
 SLC19A3



solute carrier family 19 (thiamine transporter), member 3



chr9_-_123555655 0.055 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
 FBXW2


F-box and WD repeat domain containing 2


chr21_-_16125773 0.054 ENST00000454128.2
 AF127936.3
AF127936.3
chr9_-_35828576 0.053 ENST00000377984.2
ENST00000423537.2
ENST00000472182.1
 FAM221B


family with sequence similarity 221, member B


chr14_+_96722539 0.052 ENST00000553356.1
 BDKRB1
bradykinin receptor B1
chr11_+_67171548 0.052 ENST00000542590.1
 TBC1D10C
TBC1 domain family, member 10C
chr7_+_76139833 0.051 ENST00000257632.5
 UPK3B
uroplakin 3B
chr14_-_93673353 0.051 ENST00000556566.1
ENST00000306954.4
 C14orf142

chromosome 14 open reading frame 142

chr5_-_147286065 0.049 ENST00000318315.4
ENST00000515291.1
 C5orf46

chromosome 5 open reading frame 46

chr11_+_67171391 0.048 ENST00000312390.5
 TBC1D10C
TBC1 domain family, member 10C
chr4_-_25161996 0.048 ENST00000513285.1
ENST00000382103.2
 SEPSECS

Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

chr3_-_20227619 0.047 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
 SGOL1












shugoshin-like 1 (S. pombe)












chr11_+_67171358 0.046 ENST00000526387.1
 TBC1D10C
TBC1 domain family, member 10C
chr12_+_54379569 0.046 ENST00000513209.1
 RP11-834C11.12
RP11-834C11.12
chr11_-_2323290 0.045 ENST00000381153.3
 C11orf21
chromosome 11 open reading frame 21
chrX_+_70364667 0.045 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
 NLGN3



neuroligin 3



chr11_-_62476694 0.045 ENST00000524862.1
 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_2323089 0.044 ENST00000456145.2
 C11orf21
chromosome 11 open reading frame 21
chr16_-_89556942 0.043 ENST00000301030.4
 ANKRD11
ankyrin repeat domain 11
chr10_-_73479546 0.042 ENST00000441508.2
 C10orf105
chromosome 10 open reading frame 105
chr11_+_6128914 0.041 ENST00000316529.3
 OR56B4
olfactory receptor, family 56, subfamily B, member 4
chr3_-_157251383 0.041 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
 VEPH1



ventricular zone expressed PH domain-containing 1



chr11_+_17569724 0.040 ENST00000428619.1
 OTOG
otogelin
chr8_+_102064237 0.040 ENST00000514926.1
 RP11-302J23.1
RP11-302J23.1
chr11_+_369804 0.038 ENST00000329962.6
 B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr1_+_45478568 0.038 ENST00000428106.1
 UROD
uroporphyrinogen decarboxylase
chr14_+_24422795 0.037 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
 DHRS4










dehydrogenase/reductase (SDR family) member 4










chr1_-_205601064 0.036 ENST00000357992.4
ENST00000289703.4
 ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr3_+_46919235 0.034 ENST00000449590.1
 PTH1R
parathyroid hormone 1 receptor
chr7_-_140714739 0.034 ENST00000467334.1
ENST00000324787.5
 MRPS33

mitochondrial ribosomal protein S33

chr15_+_45028753 0.034 ENST00000338264.4
 TRIM69
tripartite motif containing 69
chr12_+_26111823 0.034 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
 RASSF8


Ras association (RalGDS/AF-6) domain family (N-terminal) member 8


chr19_+_12862604 0.033 ENST00000553030.1
 BEST2
bestrophin 2
chr17_-_56358287 0.032 ENST00000225275.3
ENST00000340482.3
 MPO

myeloperoxidase

chr16_-_28608424 0.031 ENST00000335715.4
 SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_-_59917965 0.030 ENST00000548613.1
 RP11-272B17.2
Uncharacterized protein
chr16_-_54304608 0.029 ENST00000561336.1
 RP11-324D17.1
HCG2045435; Uncharacterized protein
chr19_+_12862486 0.028 ENST00000549706.1
 BEST2
bestrophin 2
chr4_-_40632757 0.028 ENST00000511902.1
ENST00000505220.1
 RBM47

RNA binding motif protein 47

chr17_+_53342311 0.026 ENST00000226067.5
 HLF
hepatic leukemia factor
chr12_-_110271178 0.025 ENST00000261740.2
ENST00000392719.2
ENST00000346520.2
 TRPV4


transient receptor potential cation channel, subfamily V, member 4


chr2_+_3642545 0.024 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
 COLEC11


collectin sub-family member 11


chr1_+_155911480 0.024 ENST00000368318.3
 RXFP4
relaxin/insulin-like family peptide receptor 4
chr20_+_816695 0.024 ENST00000246100.3
 FAM110A
family with sequence similarity 110, member A
chr2_-_208031943 0.023 ENST00000421199.1
ENST00000457962.1
 KLF7

Kruppel-like factor 7 (ubiquitous)

chr2_-_231860596 0.023 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
 AC105344.2






SPATA3 antisense RNA 1 (head to head)






chr11_+_17569375 0.023 ENST00000399397.1
 OTOG
otogelin
chr6_+_134210243 0.021 ENST00000367882.4
 TCF21
transcription factor 21
chr9_+_72658490 0.020 ENST00000377182.4
 MAMDC2
MAM domain containing 2
chrX_+_47050236 0.020 ENST00000377351.4
 UBA1
ubiquitin-like modifier activating enzyme 1
chr16_-_31147020 0.020 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
 PRSS8


protease, serine, 8


chr15_-_33447055 0.019 ENST00000559047.1
ENST00000561249.1
 FMN1

formin 1

chr7_-_116963334 0.018 ENST00000265441.3
 WNT2
wingless-type MMTV integration site family member 2
chr17_+_11924129 0.018 ENST00000353533.5
ENST00000415385.3
 MAP2K4

mitogen-activated protein kinase kinase 4

chr20_+_1115821 0.017 ENST00000435720.1
 PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr11_+_111411384 0.016 ENST00000375615.3
ENST00000525126.1
ENST00000436913.2
ENST00000533265.1
 LAYN



layilin



chr10_+_82297658 0.016 ENST00000339284.2
 SH2D4B
SH2 domain containing 4B
chr20_-_1165117 0.016 ENST00000381894.3
 TMEM74B
transmembrane protein 74B
chr2_-_27718052 0.015 ENST00000264703.3
 FNDC4
fibronectin type III domain containing 4
chr3_+_123813543 0.014 ENST00000360013.3
 KALRN
kalirin, RhoGEF kinase
chr16_-_31146961 0.011 ENST00000567531.1
 PRSS8
protease, serine, 8
chr16_-_28608364 0.011 ENST00000533150.1
 SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr12_+_98909260 0.010 ENST00000556029.1
 TMPO
thymopoietin
chr15_-_31393910 0.009 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
 TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr2_+_201997676 0.008 ENST00000462763.1
ENST00000479953.2
 CFLAR

CASP8 and FADD-like apoptosis regulator

chr20_-_1165319 0.008 ENST00000429036.1
 TMEM74B
transmembrane protein 74B
chr7_-_140714430 0.007 ENST00000393008.3
 MRPS33
mitochondrial ribosomal protein S33
chr20_+_58296265 0.006 ENST00000395636.2
ENST00000361300.4
 PHACTR3

phosphatase and actin regulator 3

chr7_-_81399438 0.006 ENST00000222390.5
 HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_-_53729525 0.006 ENST00000303846.3
 SP7
Sp7 transcription factor
chr3_+_123813509 0.006 ENST00000460856.1
ENST00000240874.3
 KALRN

kalirin, RhoGEF kinase

chr16_+_6069664 0.006 ENST00000422070.4
 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_231860830 0.006 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
 SPATA3





spermatogenesis associated 3





chr12_-_62653903 0.005 ENST00000552075.1
 FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr1_+_11249398 0.005 ENST00000376819.3
 ANGPTL7
angiopoietin-like 7
chr4_-_40632605 0.003 ENST00000514014.1
 RBM47
RNA binding motif protein 47
chr17_+_75452447 0.003 ENST00000591472.2
 SEPT9
septin 9
chr4_-_40632140 0.002 ENST00000514782.1
 RBM47
RNA binding motif protein 47
chr6_+_6588316 0.002 ENST00000379953.2
 LY86
lymphocyte antigen 86
chr14_+_74083548 0.002 ENST00000381139.1
 ACOT6
acyl-CoA thioesterase 6
chr12_-_68647281 0.001 ENST00000328087.4
ENST00000538666.1
 IL22

interleukin 22

chr11_-_64527425 0.000 ENST00000377432.3
 PYGM
phosphorylase, glycogen, muscle

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.8 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 1.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0045360 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules