Motif ID: GUGCAAA

Z-value: 1.198


Mature miRNA associated with seed GUGCAAA:

NamemiRBase Accession
hsa-miR-19a-3p MIMAT0000073
hsa-miR-19b-3p MIMAT0000074



Activity profile for motif GUGCAAA.

activity profile for motif GUGCAAA


Sorted Z-values histogram for motif GUGCAAA

Sorted Z-values for motif GUGCAAA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUGCAAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132272504 1.892 ENST00000367976.3
CTGF
connective tissue growth factor
chr15_+_39873268 1.834 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr6_+_138188551 1.377 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr16_+_3070313 1.243 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr5_-_136834982 1.184 ENST00000510689.1
ENST00000394945.1
SPOCK1

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1

chr3_-_66551351 1.082 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr10_+_28966271 0.926 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr10_+_23728198 0.882 ENST00000376495.3
OTUD1
OTU domain containing 1
chr17_-_76356148 0.880 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr2_+_70142189 0.873 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr3_-_52090461 0.783 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr3_-_192635943 0.757 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr12_-_49463753 0.757 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr5_-_150460539 0.739 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1



TNFAIP3 interacting protein 1



chr9_+_115913222 0.661 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr8_-_67525473 0.653 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr5_-_73937244 0.649 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1


ectodermal-neural cortex 1 (with BTB domain)


chr3_-_151176497 0.643 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr3_-_64211112 0.632 ENST00000295902.6
PRICKLE2
prickle homolog 2 (Drosophila)
chr15_+_98503922 0.632 ENST00000268042.6
ARRDC4
arrestin domain containing 4
chr12_+_96588143 0.619 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr20_-_48330377 0.595 ENST00000371711.4
B4GALT5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr4_+_160188889 0.588 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_-_95007193 0.586 ENST00000370207.4
ENST00000334047.7
F3

coagulation factor III (thromboplastin, tissue factor)

chr3_+_150804676 0.561 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr4_+_139936905 0.556 ENST00000280614.2
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr3_+_67048721 0.530 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8



kelch repeat and BTB (POZ) domain containing 8



chr7_+_20370746 0.495 ENST00000222573.4
ITGB8
integrin, beta 8
chr12_+_72148614 0.492 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr3_+_30648066 0.492 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_-_185826855 0.490 ENST00000306376.5
ETV5
ets variant 5
chr1_+_64239657 0.476 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr9_-_16870704 0.465 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2



basonuclin 2



chr4_+_75174180 0.458 ENST00000413830.1
EPGN
epithelial mitogen
chr14_-_53619816 0.457 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1


DDHD domain containing 1


chr8_-_103668114 0.448 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr3_+_194406603 0.448 ENST00000329759.4
FAM43A
family with sequence similarity 43, member A
chr19_-_14629224 0.442 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_-_149982624 0.439 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr15_-_73925651 0.438 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN


neuroplastin


chrX_-_18372792 0.431 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr20_-_52210368 0.424 ENST00000371471.2
ZNF217
zinc finger protein 217
chr8_-_110660999 0.420 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
SYBU







syntabulin (syntaxin-interacting)







chr16_-_47007545 0.410 ENST00000317089.5
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr3_-_160283348 0.405 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr2_+_101436564 0.402 ENST00000335681.5
NPAS2
neuronal PAS domain protein 2
chr1_+_24069642 0.399 ENST00000418390.2
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr13_+_49550015 0.397 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr3_+_171758344 0.393 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chrX_+_41192595 0.386 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr11_-_19263145 0.385 ENST00000532666.1
ENST00000527884.1
E2F8

E2F transcription factor 8

chr1_-_244615425 0.377 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr3_+_152017181 0.371 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr2_+_134877740 0.363 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chrX_-_10645773 0.357 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_27153173 0.356 ENST00000374142.4
ZDHHC18
zinc finger, DHHC-type containing 18
chr13_-_27745936 0.348 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr7_-_5821314 0.347 ENST00000425013.2
ENST00000389902.3
RNF216

ring finger protein 216

chr17_-_80606304 0.347 ENST00000392325.4
WDR45B
WD repeat domain 45B
chr16_+_50775948 0.344 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD


cylindromatosis (turban tumor syndrome)


chr10_-_15210666 0.344 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr3_-_53080047 0.340 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr20_+_37554955 0.339 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr14_+_55034599 0.338 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr9_-_130742792 0.333 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr6_-_42419649 0.328 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr5_+_125935960 0.325 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chrX_+_118108571 0.322 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr14_-_81687197 0.320 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr7_-_105517021 0.318 ENST00000318724.4
ENST00000419735.3
ATXN7L1

ataxin 7-like 1

chr7_-_98741642 0.318 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr1_+_16174280 0.313 ENST00000375759.3
SPEN
spen family transcriptional repressor
chr16_+_21169976 0.312 ENST00000572258.1
ENST00000261388.3
ENST00000451578.2
ENST00000572599.1
ENST00000577162.1
TMEM159




transmembrane protein 159




chr8_-_12612962 0.309 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chrX_-_108976521 0.306 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4




acyl-CoA synthetase long-chain family member 4




chr5_-_132073210 0.302 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chrX_-_135056216 0.301 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr16_-_46655538 0.299 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr11_-_118023490 0.297 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr3_+_137906109 0.297 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8



armadillo repeat containing 8



chr15_-_49338748 0.292 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr1_-_115053781 0.289 ENST00000358465.2
ENST00000369543.2
TRIM33

tripartite motif containing 33

chr1_+_101361626 0.287 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr8_+_28351707 0.286 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr2_-_85555385 0.285 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr12_-_93323013 0.285 ENST00000322349.8
EEA1
early endosome antigen 1
chr1_-_25291475 0.282 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr22_-_46373004 0.282 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chrX_+_46433193 0.282 ENST00000276055.3
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr18_+_8717369 0.281 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2


SOGA family member 2


chr2_-_153032484 0.280 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr20_-_48532019 0.279 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr5_+_179159813 0.278 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr17_-_62658186 0.277 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr15_+_52311398 0.272 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chrX_-_19905703 0.270 ENST00000397821.3
SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_71705590 0.269 ENST00000254799.6
GRSF1
G-rich RNA sequence binding factor 1
chr20_+_47662805 0.268 ENST00000262982.2
ENST00000542325.1
CSE1L

CSE1 chromosome segregation 1-like (yeast)

chr10_-_71930222 0.265 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A



SAR1 homolog A (S. cerevisiae)



chr10_-_75173785 0.258 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
ANXA7


annexin A7


chr9_-_26947453 0.258 ENST00000397292.3
PLAA
phospholipase A2-activating protein
chr8_-_103876965 0.256 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr16_+_67143880 0.255 ENST00000219139.3
ENST00000566026.1
C16orf70

chromosome 16 open reading frame 70

chr1_+_162467595 0.249 ENST00000538489.1
ENST00000489294.1
UHMK1

U2AF homology motif (UHM) kinase 1

chr1_+_51701924 0.249 ENST00000242719.3
RNF11
ring finger protein 11
chr14_+_74111578 0.248 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr2_+_62932779 0.248 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1


EH domain binding protein 1


chr14_-_61116168 0.247 ENST00000247182.6
SIX1
SIX homeobox 1
chr1_+_32573636 0.245 ENST00000373625.3
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr10_+_90639491 0.245 ENST00000371926.3
ENST00000371927.3
STAMBPL1

STAM binding protein-like 1

chr17_+_21187976 0.245 ENST00000342679.4
MAP2K3
mitogen-activated protein kinase kinase 3
chr11_+_58346584 0.245 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr19_+_11200038 0.244 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR





low density lipoprotein receptor





chr20_+_19867150 0.241 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr10_+_115803650 0.240 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr2_+_231577532 0.237 ENST00000258418.5
CAB39
calcium binding protein 39
chr4_-_152147579 0.237 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19



SH3 domain containing 19



chr2_-_128643496 0.236 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr5_+_138940742 0.234 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
UBE2D2


ubiquitin-conjugating enzyme E2D 2


chr1_+_193091080 0.233 ENST00000367435.3
CDC73
cell division cycle 73
chr16_-_11350036 0.233 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr2_-_39664405 0.232 ENST00000341681.5
ENST00000263881.3
MAP4K3

mitogen-activated protein kinase kinase kinase kinase 3

chr18_+_3451646 0.232 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1


TGFB-induced factor homeobox 1


chr2_-_161350305 0.231 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_+_114472222 0.231 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr1_+_160175117 0.230 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr17_+_56160768 0.229 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr2_-_69870835 0.229 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr15_+_32907691 0.225 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
ARHGAP11A



Rho GTPase activating protein 11A



chr6_-_116381918 0.225 ENST00000606080.1
FRK
fyn-related kinase
chr2_+_173292301 0.223 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chr6_+_1389989 0.222 ENST00000259806.1
FOXF2
forkhead box F2
chr12_+_104458235 0.222 ENST00000229330.4
HCFC2
host cell factor C2
chr1_-_243418344 0.221 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr8_+_87354945 0.221 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr12_+_67663056 0.220 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr12_+_79258547 0.219 ENST00000457153.2
SYT1
synaptotagmin I
chr18_+_59854480 0.218 ENST00000256858.6
ENST00000398130.2
KIAA1468

KIAA1468

chr11_-_59436453 0.217 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr17_-_5372271 0.216 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr11_+_123396528 0.215 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr3_+_57741957 0.213 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr9_-_115983641 0.213 ENST00000238256.3
FKBP15
FK506 binding protein 15, 133kDa
chr1_-_67519782 0.210 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr15_+_63481668 0.207 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B


RAB8B, member RAS oncogene family


chr1_+_178694300 0.207 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_100867864 0.206 ENST00000442697.2
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr12_-_59313270 0.206 ENST00000379141.4
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr9_-_74980113 0.205 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5


zinc finger, AN1-type domain 5


chr20_-_60640866 0.205 ENST00000252996.4
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr12_+_69864129 0.205 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr2_+_9346892 0.204 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr12_+_27932803 0.203 ENST00000381271.2
KLHL42
kelch-like family member 42
chr1_+_32645269 0.202 ENST00000373610.3
TXLNA
taxilin alpha
chr14_+_96829814 0.201 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSKIP


GSK3B interacting protein


chr3_+_29322803 0.201 ENST00000396583.3
ENST00000383767.2
RBMS3

RNA binding motif, single stranded interacting protein 3

chr15_+_40532058 0.201 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_78245303 0.200 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr15_+_80987617 0.199 ENST00000258884.4
ENST00000558464.1
ABHD17C

abhydrolase domain containing 17C

chr3_-_138553594 0.199 ENST00000477593.1
ENST00000483968.1
PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

chr1_-_27481401 0.198 ENST00000263980.3
SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr4_-_10118469 0.198 ENST00000499869.2
WDR1
WD repeat domain 1
chr2_-_225811747 0.197 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr10_+_65281123 0.195 ENST00000298249.4
ENST00000373758.4
REEP3

receptor accessory protein 3

chr1_+_28696111 0.195 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr7_+_39989611 0.194 ENST00000181839.4
CDK13
cyclin-dependent kinase 13
chr1_-_235491462 0.194 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
ARID4B


AT rich interactive domain 4B (RBP1-like)


chr14_+_31028329 0.194 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr16_-_85045131 0.193 ENST00000313732.4
ZDHHC7
zinc finger, DHHC-type containing 7
chr15_+_59279851 0.190 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111


ring finger protein 111


chr4_+_152330390 0.189 ENST00000503146.1
ENST00000435205.1
FAM160A1

family with sequence similarity 160, member A1

chr9_-_138799070 0.189 ENST00000389532.4
ENST00000409386.3
CAMSAP1

calmodulin regulated spectrin-associated protein 1

chr19_-_12834739 0.189 ENST00000589337.1
ENST00000425528.1
ENST00000441499.1
ENST00000588216.1
TNPO2



transportin 2



chr1_-_27339317 0.188 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr12_+_22778009 0.188 ENST00000266517.4
ENST00000335148.3
ETNK1

ethanolamine kinase 1

chr1_-_70671216 0.183 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr4_+_128703295 0.183 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr20_+_1246908 0.183 ENST00000381873.3
ENST00000381867.1
SNPH

syntaphilin

chr6_-_86352642 0.182 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_+_149402553 0.182 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr10_-_27529716 0.181 ENST00000375897.3
ENST00000396271.3
ACBD5

acyl-CoA binding domain containing 5

chr11_+_69455855 0.180 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr4_+_71768043 0.179 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B


MOB kinase activator 1B


chr3_+_43732362 0.179 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr8_-_119124045 0.176 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr3_-_156877997 0.173 ENST00000295926.3
CCNL1
cyclin L1
chr1_-_117210290 0.173 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chrX_+_44732757 0.172 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
KDM6A



lysine (K)-specific demethylase 6A



chr2_+_191273052 0.172 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
MFSD6


major facilitator superfamily domain containing 6


chr20_-_50159198 0.170 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chrX_+_118708493 0.169 ENST00000371558.2
UBE2A
ubiquitin-conjugating enzyme E2A
chr4_+_79697495 0.167 ENST00000502871.1
ENST00000335016.5
BMP2K

BMP2 inducible kinase

chrX_+_16804544 0.166 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr12_-_100536608 0.166 ENST00000356828.3
ENST00000279907.7
UHRF1BP1L

UHRF1 binding protein 1-like

chr2_-_208030647 0.165 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_51984908 0.165 ENST00000371730.2
EPS15
epidermal growth factor receptor pathway substrate 15
chr20_-_524455 0.164 ENST00000349736.5
ENST00000217244.3
CSNK2A1

casein kinase 2, alpha 1 polypeptide

chr1_+_109632425 0.163 ENST00000338272.8
TMEM167B
transmembrane protein 167B
chr2_+_64751433 0.162 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH


aftiphilin


chr16_+_67063036 0.160 ENST00000290858.6
ENST00000564034.1
CBFB

core-binding factor, beta subunit


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0034059 response to anoxia(GO:0034059)
0.6 1.8 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.5 1.4 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 1.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.7 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 1.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.6 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 0.2 GO:0001743 optic placode formation(GO:0001743)
0.1 0.2 GO:2000729 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 0.4 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.2 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.2 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0070662 mast cell proliferation(GO:0070662)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.5 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 1.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.5 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.1 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.3 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.2 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 2.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939) alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.3 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 2.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.6 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway