Motif ID: GTF2I

Z-value: 0.761


Transcription factors associated with GTF2I:

Gene SymbolEntrez IDGene Name
GTF2I ENSG00000077809.8 GTF2I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GTF2Ihg19_v2_chr7_+_74072288_740723570.333.9e-01Click!


Activity profile for motif GTF2I.

activity profile for motif GTF2I


Sorted Z-values histogram for motif GTF2I

Sorted Z-values for motif GTF2I



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_50094866 0.837 ENST00000418929.2
PRR12
proline rich 12
chr1_-_27930102 0.723 ENST00000247087.5
ENST00000374011.2
AHDC1

AT hook, DNA binding motif, containing 1

chr6_-_42418999 0.429 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr1_+_167190066 0.387 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU2F1




POU class 2 homeobox 1




chr2_-_75788038 0.369 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr1_+_36024107 0.365 ENST00000437806.1
NCDN
neurochondrin
chr7_+_100770328 0.363 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_+_86046433 0.361 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr12_+_13044787 0.359 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr2_-_75788424 0.348 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr1_+_27022839 0.339 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_+_154975258 0.329 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr6_+_41514078 0.321 ENST00000373063.3
ENST00000373060.1
FOXP4

forkhead box P4

chr12_-_1703331 0.320 ENST00000339235.3
FBXL14
F-box and leucine-rich repeat protein 14
chr2_-_75788428 0.319 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr6_+_41514305 0.306 ENST00000409208.1
ENST00000373057.3
FOXP4

forkhead box P4

chr1_+_27022485 0.305 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr2_-_227664474 0.303 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr12_-_124873357 0.302 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr12_-_50222187 0.293 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr8_-_145018080 0.288 ENST00000354589.3
PLEC
plectin
chrX_+_129116586 0.271 ENST00000218147.7
ENST00000303743.5
ENST00000359304.2
BCORL1


BCL6 corepressor-like 1


chr8_-_41909496 0.265 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr1_+_173837488 0.244 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37


zinc finger and BTB domain containing 37


chr16_+_69599899 0.241 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr18_+_46065570 0.238 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr1_+_157963391 0.224 ENST00000359209.6
ENST00000416935.2
KIRREL

kin of IRRE like (Drosophila)

chr2_+_149402989 0.222 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_+_42773371 0.220 ENST00000571942.2
CIC
capicua transcriptional repressor
chr12_+_46123682 0.218 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr16_-_4323015 0.217 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr10_-_92681033 0.216 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr17_+_37617721 0.211 ENST00000584632.1
CDK12
cyclin-dependent kinase 12
chr19_+_56652643 0.211 ENST00000586123.1
ZNF444
zinc finger protein 444
chr19_+_46498704 0.206 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61


coiled-coil domain containing 61


chr6_-_47277634 0.204 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr22_-_46373004 0.201 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr5_+_137673945 0.199 ENST00000513056.1
ENST00000511276.1
FAM53C

family with sequence similarity 53, member C

chr12_-_48213735 0.197 ENST00000417902.1
ENST00000417107.1
HDAC7

histone deacetylase 7

chr19_-_14316980 0.197 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr3_-_195619579 0.196 ENST00000428187.1
TNK2
tyrosine kinase, non-receptor, 2
chr10_-_75532373 0.195 ENST00000595757.1
AC022400.2
Uncharacterized protein; cDNA FLJ44715 fis, clone BRACE3021430
chr6_-_42419649 0.194 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr7_+_150758642 0.188 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr1_+_157963063 0.186 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL


kin of IRRE like (Drosophila)


chr6_+_36164487 0.185 ENST00000357641.6
BRPF3
bromodomain and PHD finger containing, 3
chr12_+_58120044 0.184 ENST00000542466.2
AGAP2-AS1
AGAP2 antisense RNA 1
chr19_+_50433476 0.184 ENST00000596658.1
ATF5
activating transcription factor 5
chr1_+_39734131 0.183 ENST00000530262.1
MACF1
microtubule-actin crosslinking factor 1
chr9_+_4490394 0.182 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr13_-_45151259 0.182 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr9_+_35538616 0.182 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr1_-_155532484 0.182 ENST00000368346.3
ENST00000548830.1
ASH1L

ash1 (absent, small, or homeotic)-like (Drosophila)

chr17_+_46132037 0.181 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1


nuclear factor, erythroid 2-like 1


chr14_-_21905424 0.180 ENST00000553622.1
CHD8
chromodomain helicase DNA binding protein 8
chr16_+_69600058 0.179 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr19_-_2015699 0.178 ENST00000255608.4
BTBD2
BTB (POZ) domain containing 2
chr17_+_46131912 0.177 ENST00000584634.1
ENST00000580050.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr12_+_49209348 0.176 ENST00000536187.2
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr1_-_32264356 0.176 ENST00000452755.2
SPOCD1
SPOC domain containing 1
chr16_+_69599861 0.174 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr3_-_134092561 0.173 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2


angiomotin like 2


chr12_+_53491220 0.173 ENST00000548547.1
ENST00000301464.3
IGFBP6

insulin-like growth factor binding protein 6

chr16_+_30935418 0.173 ENST00000338343.4
FBXL19
F-box and leucine-rich repeat protein 19
chr19_+_42788172 0.172 ENST00000160740.3
CIC
capicua transcriptional repressor
chr2_-_72374948 0.172 ENST00000546307.1
ENST00000474509.1
CYP26B1

cytochrome P450, family 26, subfamily B, polypeptide 1

chr6_+_31588478 0.171 ENST00000376007.4
ENST00000376033.2
PRRC2A

proline-rich coiled-coil 2A

chr11_-_57089774 0.171 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr8_-_145013711 0.171 ENST00000345136.3
PLEC
plectin
chr12_+_56915776 0.169 ENST00000550726.1
ENST00000542360.1
RBMS2

RNA binding motif, single stranded interacting protein 2

chr17_+_46131843 0.168 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr16_+_30934376 0.168 ENST00000562798.1
ENST00000471231.2
FBXL19

F-box and leucine-rich repeat protein 19

chr12_+_56915713 0.167 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr22_-_30642728 0.167 ENST00000403987.3
LIF
leukemia inhibitory factor
chr17_-_4852332 0.166 ENST00000572383.1
PFN1
profilin 1
chr19_+_3366547 0.166 ENST00000341919.3
ENST00000590282.1
ENST00000443272.2
NFIC


nuclear factor I/C (CCAAT-binding transcription factor)


chr2_-_73511407 0.164 ENST00000520530.2
FBXO41
F-box protein 41
chr7_-_5465045 0.163 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr12_+_133067157 0.162 ENST00000261673.6
FBRSL1
fibrosin-like 1
chr16_+_29818857 0.162 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_30996502 0.161 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7




hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7




chr2_-_217236750 0.159 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr11_-_72385437 0.158 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A


phosphodiesterase 2A, cGMP-stimulated


chr5_-_149682447 0.158 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr17_-_40828969 0.157 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3


pleckstrin homology domain containing, family H (with MyTH4 domain) member 3


chr14_+_38065052 0.155 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr19_-_54692132 0.155 ENST00000449249.1
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr1_+_154975110 0.153 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr1_-_32264250 0.153 ENST00000528579.1
SPOCD1
SPOC domain containing 1
chr9_+_109625378 0.150 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462


zinc finger protein 462


chr11_+_7506837 0.148 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr15_-_37392724 0.146 ENST00000424352.2
MEIS2
Meis homeobox 2
chr2_+_74229812 0.146 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr1_+_53793885 0.145 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr19_-_50990785 0.143 ENST00000595005.1
CTD-2545M3.8
CTD-2545M3.8
chr5_+_92919043 0.142 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr19_-_4065730 0.142 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_150758304 0.142 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2


solute carrier family 4 (anion exchanger), member 2


chr17_+_37618257 0.142 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr2_-_240322685 0.141 ENST00000544989.1
HDAC4
histone deacetylase 4
chr9_-_4299874 0.141 ENST00000381971.3
ENST00000477901.1
GLIS3

GLIS family zinc finger 3

chr2_+_149402553 0.140 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr7_+_55086703 0.140 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR



epidermal growth factor receptor



chr7_+_143079000 0.139 ENST00000392910.2
ZYX
zyxin
chr19_+_48112371 0.139 ENST00000594866.1
GLTSCR1
glioma tumor suppressor candidate region gene 1
chr19_+_36208877 0.138 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B


Histone-lysine N-methyltransferase 2B


chr17_-_42188598 0.138 ENST00000591714.1
HDAC5
histone deacetylase 5
chr19_+_34287174 0.138 ENST00000587559.1
ENST00000588637.1
KCTD15

potassium channel tetramerization domain containing 15

chr7_-_100425112 0.138 ENST00000358173.3
EPHB4
EPH receptor B4
chr17_+_7308172 0.137 ENST00000575301.1
NLGN2
neuroligin 2
chr1_-_156470515 0.137 ENST00000340875.5
ENST00000368240.2
ENST00000353795.3
MEF2D


myocyte enhancer factor 2D


chr4_+_160188306 0.136 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_-_48213568 0.136 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7




histone deacetylase 7




chr1_-_156470556 0.136 ENST00000489057.1
ENST00000348159.4
MEF2D

myocyte enhancer factor 2D

chr1_-_16482554 0.135 ENST00000358432.5
EPHA2
EPH receptor A2
chr19_+_54369434 0.133 ENST00000421337.1
MYADM
myeloid-associated differentiation marker
chr2_-_220408430 0.132 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr20_+_1246908 0.132 ENST00000381873.3
ENST00000381867.1
SNPH

syntaphilin

chr19_+_1275917 0.130 ENST00000469144.1
C19orf24
chromosome 19 open reading frame 24
chr18_+_46065483 0.130 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr8_+_22250334 0.130 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_-_31869769 0.129 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chr19_+_55999771 0.129 ENST00000594321.1
SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr9_+_124329336 0.129 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr6_-_10412600 0.129 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_-_45909585 0.128 ENST00000593226.1
ENST00000418234.2
PPP1R13L

protein phosphatase 1, regulatory subunit 13 like

chr12_-_54813229 0.128 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_14063278 0.127 ENST00000254337.6
DCAF15
DDB1 and CUL4 associated factor 15
chr16_-_57809015 0.127 ENST00000540079.2
ENST00000569222.1
KIFC3

kinesin family member C3

chr1_+_14075903 0.127 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2



PR domain containing 2, with ZNF domain



chr4_-_74124502 0.127 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ANKRD17


ankyrin repeat domain 17


chr22_-_36236265 0.125 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr17_+_45973516 0.124 ENST00000376741.4
SP2
Sp2 transcription factor
chr16_+_2820912 0.124 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr1_+_223889310 0.123 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr19_-_10679697 0.122 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_+_110163202 0.122 ENST00000531203.1
ENST00000256578.3
AMPD2

adenosine monophosphate deaminase 2

chr17_-_73839792 0.122 ENST00000590762.1
UNC13D
unc-13 homolog D (C. elegans)
chr15_-_59041954 0.121 ENST00000439637.1
ENST00000558004.1
ADAM10

ADAM metallopeptidase domain 10

chr1_-_204329013 0.121 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr16_+_67312049 0.121 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr17_-_982198 0.120 ENST00000571945.1
ENST00000536794.2
ABR

active BCR-related

chr16_+_30935896 0.119 ENST00000562319.1
ENST00000380310.2
FBXL19

F-box and leucine-rich repeat protein 19

chr16_+_725650 0.118 ENST00000352681.3
ENST00000561556.1
RHBDL1

rhomboid, veinlet-like 1 (Drosophila)

chrX_-_153141783 0.117 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr16_+_29817399 0.117 ENST00000545521.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_7506713 0.116 ENST00000329293.3
ENST00000534244.1
OLFML1

olfactomedin-like 1

chr15_+_90544532 0.116 ENST00000268154.4
ZNF710
zinc finger protein 710
chr17_-_40829026 0.116 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr8_-_21988558 0.115 ENST00000312841.8
HR
hair growth associated
chr5_+_150040403 0.115 ENST00000517768.1
ENST00000297130.4
MYOZ3

myozenin 3

chr1_+_15480197 0.115 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51


transmembrane protein 51


chr14_-_61191049 0.115 ENST00000556952.3
SIX4
SIX homeobox 4
chr15_+_75074410 0.114 ENST00000439220.2
CSK
c-src tyrosine kinase
chr10_+_70980051 0.113 ENST00000354624.5
ENST00000395086.2
HKDC1

hexokinase domain containing 1

chr22_-_30642782 0.112 ENST00000249075.3
LIF
leukemia inhibitory factor
chr3_+_67048721 0.112 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8



kelch repeat and BTB (POZ) domain containing 8



chr12_+_46123448 0.112 ENST00000334344.6
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr15_+_75074915 0.112 ENST00000567123.1
ENST00000569462.1
CSK

c-src tyrosine kinase

chr6_-_10413112 0.112 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_48133459 0.111 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_+_45445491 0.110 ENST00000589057.1
ENST00000592954.1
ENST00000419266.2
APOC4-APOC2
APOC4

APOC4-APOC2 readthrough (NMD candidate)
apolipoprotein C-IV

chr19_+_42772659 0.110 ENST00000572681.2
CIC
capicua transcriptional repressor
chr11_+_76777979 0.110 ENST00000531028.1
ENST00000278559.3
ENST00000527066.1
ENST00000529629.1
CAPN5



calpain 5



chr9_+_96717821 0.110 ENST00000454594.1
RP11-231K24.2
RP11-231K24.2
chr16_+_28835437 0.110 ENST00000568266.1
ATXN2L
ataxin 2-like
chr20_-_10654639 0.110 ENST00000254958.5
JAG1
jagged 1
chr17_-_76356148 0.110 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr16_-_57836321 0.109 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
KIFC3



kinesin family member C3



chr14_-_21905395 0.109 ENST00000430710.3
ENST00000553283.1
CHD8

chromodomain helicase DNA binding protein 8

chr19_+_54372877 0.109 ENST00000414489.1
MYADM
myeloid-associated differentiation marker
chr19_-_46272106 0.109 ENST00000560168.1
SIX5
SIX homeobox 5
chr1_-_155948218 0.109 ENST00000313667.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr5_+_149865838 0.109 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_+_67390920 0.109 ENST00000559092.1
ENST00000560175.1
SMAD3

SMAD family member 3

chr2_-_230786619 0.109 ENST00000389045.3
ENST00000409677.1
TRIP12

thyroid hormone receptor interactor 12

chr17_-_41623075 0.108 ENST00000545089.1
ETV4
ets variant 4
chr16_-_29874211 0.107 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr1_+_173837214 0.107 ENST00000367704.1
ZBTB37
zinc finger and BTB domain containing 37
chr2_-_61697862 0.106 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr11_-_3186551 0.105 ENST00000533234.1
OSBPL5
oxysterol binding protein-like 5
chr17_+_48133330 0.105 ENST00000544892.1
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr14_-_54423529 0.105 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr3_-_134093275 0.105 ENST00000513145.1
ENST00000422605.2
AMOTL2

angiomotin like 2

chr10_-_75351088 0.104 ENST00000451492.1
ENST00000413442.1
USP54

ubiquitin specific peptidase 54

chr1_+_203096831 0.104 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr6_-_33282024 0.104 ENST00000475304.1
ENST00000489157.1
TAPBP

TAP binding protein (tapasin)

chr17_+_73750699 0.103 ENST00000584939.1
ITGB4
integrin, beta 4
chr19_+_17858509 0.103 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1


FCH domain only 1


chr9_-_14314518 0.102 ENST00000397581.2
NFIB
nuclear factor I/B
chr1_-_115632035 0.101 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2



tetraspanin 2



chr16_-_67969888 0.101 ENST00000574576.2
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr19_-_49015050 0.100 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr12_-_57030115 0.100 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A


bromodomain adjacent to zinc finger domain, 2A


chr1_+_201617450 0.100 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1


neuron navigator 1


chr17_-_73840774 0.099 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chrX_+_73641286 0.099 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr1_-_42384343 0.099 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr16_-_73082274 0.099 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr12_-_122018859 0.099 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B


lysine (K)-specific demethylase 2B



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.8 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0002432 granuloma formation(GO:0002432)
0.1 0.3 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.2 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.2 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:0048320 axial mesoderm formation(GO:0048320)
0.1 0.1 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.0 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.5 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:1990575 mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.0 GO:0048565 digestive tract development(GO:0048565)
0.0 0.2 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0032242 negative regulation of glutamate secretion(GO:0014050) regulation of nucleoside transport(GO:0032242)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:1905045 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.0 GO:0060067 cervix development(GO:0060067)
0.0 0.0 GO:0016071 mRNA metabolic process(GO:0016071)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.4 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0007037 vacuolar phosphate transport(GO:0007037) negative regulation of fibroblast growth factor production(GO:0090272) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.1 GO:1901545 proepicardium development(GO:0003342) septum transversum development(GO:0003343) cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.0 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.0 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.0 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.0 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.0 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.0 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0021855 hypothalamus cell migration(GO:0021855)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.0 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0030055 cell-substrate junction(GO:0030055)
0.0 0.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.0 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 1.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation