• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: GLIS3

Z-value: 0.383

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_150758642	0.310	ENST00000488420.1	SLC4A2	solute carrier family 4 (anion exchanger), member 2
chr19_-_48673465	0.268	ENST00000598938.1	LIG1	ligase I, DNA, ATP-dependent
chr19_-_41859814	0.218	ENST00000221930.5	TGFB1	transforming growth factor, beta 1
chr20_-_30310693	0.215	ENST00000307677.4 ENST00000420653.1	BCL2L1	BCL2-like 1
chr19_+_40697514	0.214	ENST00000253055.3	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr19_-_10613862	0.213	ENST00000592055.1	KEAP1	kelch-like ECH-associated protein 1
chr20_-_30310656	0.208	ENST00000376055.4	BCL2L1	BCL2-like 1
chr19_+_48828582	0.206	ENST00000270221.6 ENST00000596315.1	EMP3	epithelial membrane protein 3
chr19_-_10613361	0.204	ENST00000591039.1 ENST00000591419.1	KEAP1	kelch-like ECH-associated protein 1
chr1_+_31886653	0.199	ENST00000536384.1	SERINC2	serine incorporator 2
chr1_-_157108130	0.186	ENST00000368192.4	ETV3	ets variant 3
chr20_+_61867235	0.184	ENST00000342412.6 ENST00000217169.3	BIRC7	baculoviral IAP repeat containing 7
chr22_+_50628999	0.176	ENST00000395827.1	TRABD	TraB domain containing
chr11_+_68671310	0.171	ENST00000255078.3 ENST00000539224.1	IGHMBP2	immunoglobulin mu binding protein 2
chr1_-_157108266	0.166	ENST00000326786.4	ETV3	ets variant 3
chr7_+_150758304	0.164	ENST00000482950.1 ENST00000463414.1 ENST00000310317.5	SLC4A2	solute carrier family 4 (anion exchanger), member 2
chr18_+_3451584	0.151	ENST00000551541.1	TGIF1	TGFB-induced factor homeobox 1
chr9_-_130742792	0.136	ENST00000373095.1	FAM102A	family with sequence similarity 102, member A
chr11_-_118789613	0.135	ENST00000532899.1	BCL9L	B-cell CLL/lymphoma 9-like
chr7_+_65958693	0.129	ENST00000445681.1 ENST00000452565.1	GS1-124K5.4	GS1-124K5.4
chr16_+_30006615	0.121	ENST00000563197.1	INO80E	INO80 complex subunit E
chr18_+_3451646	0.121	ENST00000345133.5 ENST00000330513.5 ENST00000549546.1	TGIF1	TGFB-induced factor homeobox 1
chr17_-_77925806	0.118	ENST00000574241.2	TBC1D16	TBC1 domain family, member 16
chr1_-_92371839	0.115	ENST00000370399.2	TGFBR3	transforming growth factor, beta receptor III
chr22_-_50964849	0.113	ENST00000543927.1 ENST00000423348.1	SCO2	SCO2 cytochrome c oxidase assembly protein
chr22_-_32022280	0.100	ENST00000442379.1	PISD	phosphatidylserine decarboxylase
chr19_+_46850251	0.094	ENST00000012443.4	PPP5C	protein phosphatase 5, catalytic subunit
chr6_+_24495185	0.090	ENST00000348925.2	ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr12_+_132312931	0.089	ENST00000360564.1 ENST00000545671.1 ENST00000545790.1	MMP17	matrix metallopeptidase 17 (membrane-inserted)
chr5_+_41925325	0.088	ENST00000296812.2 ENST00000281623.3 ENST00000509134.1	FBXO4	F-box protein 4
chr10_+_71389983	0.088	ENST00000373279.4	C10orf35	chromosome 10 open reading frame 35
chr9_-_98279241	0.088	ENST00000437951.1 ENST00000375274.2 ENST00000430669.2 ENST00000468211.2	PTCH1	patched 1
chr19_+_46850320	0.087	ENST00000391919.1	PPP5C	protein phosphatase 5, catalytic subunit
chr19_-_10613421	0.082	ENST00000393623.2	KEAP1	kelch-like ECH-associated protein 1
chr11_+_393428	0.078	ENST00000533249.1 ENST00000527442.1	PKP3	plakophilin 3
chr1_-_247095236	0.076	ENST00000478568.1	AHCTF1	AT hook containing transcription factor 1
chr20_-_44718538	0.074	ENST00000290231.6 ENST00000372291.3	NCOA5	nuclear receptor coactivator 5
chr11_+_66886717	0.072	ENST00000398645.2	KDM2A	lysine (K)-specific demethylase 2A
chr12_+_48152774	0.070	ENST00000549243.1	SLC48A1	solute carrier family 48 (heme transporter), member 1
chr6_+_24495067	0.066	ENST00000357578.3 ENST00000546278.1 ENST00000491546.1	ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr12_-_57400227	0.065	ENST00000300101.2	ZBTB39	zinc finger and BTB domain containing 39
chr5_-_180671172	0.060	ENST00000512805.1	GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr8_+_27183033	0.057	ENST00000420218.2	PTK2B	protein tyrosine kinase 2 beta
chr1_+_33207381	0.053	ENST00000401073.2	KIAA1522	KIAA1522
chr19_-_56092187	0.053	ENST00000325421.4 ENST00000592239.1	ZNF579	zinc finger protein 579
chr18_+_11751493	0.049	ENST00000269162.5	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr22_-_31742218	0.048	ENST00000266269.5 ENST00000405309.3 ENST00000351933.4	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr11_-_8680383	0.040	ENST00000299550.6	TRIM66	tripartite motif containing 66
chr3_+_173116225	0.037	ENST00000457714.1	NLGN1	neuroligin 1
chrX_+_64887512	0.035	ENST00000360270.5	MSN	moesin
chr17_-_33446820	0.034	ENST00000592577.1 ENST00000590016.1 ENST00000345365.6 ENST00000360276.3 ENST00000357906.3	RAD51D	RAD51 paralog D
chr1_-_22215192	0.032	ENST00000374673.3	HSPG2	heparan sulfate proteoglycan 2
chr6_+_44191290	0.031	ENST00000371755.3 ENST00000371740.5 ENST00000371731.1 ENST00000393841.1	SLC29A1	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr17_-_5015129	0.029	ENST00000575898.1 ENST00000416429.2	ZNF232	zinc finger protein 232
chr6_+_44191507	0.029	ENST00000371724.1 ENST00000371713.1	SLC29A1	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr22_-_21482352	0.028	ENST00000329949.3	POM121L7	POM121 transmembrane nucleoporin-like 7
chr15_+_91478493	0.028	ENST00000418476.2	UNC45A	unc-45 homolog A (C. elegans)
chr5_+_72509751	0.027	ENST00000515556.1 ENST00000513379.1 ENST00000427584.2	RP11-60A8.1	RP11-60A8.1
chr2_+_219824357	0.026	ENST00000302625.4	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr5_+_172386517	0.025	ENST00000519522.1	RPL26L1	ribosomal protein L26-like 1
chr1_+_107599267	0.024	ENST00000361318.5 ENST00000370078.1	PRMT6	protein arginine methyltransferase 6
chr12_+_132568814	0.024	ENST00000454179.2 ENST00000389560.2 ENST00000443539.2 ENST00000392352.1	EP400NL	EP400 N-terminal like
chr21_+_38071430	0.022	ENST00000290399.6	SIM2	single-minded family bHLH transcription factor 2
chr2_-_208030295	0.019	ENST00000458272.1	KLF7	Kruppel-like factor 7 (ubiquitous)
chr8_-_12051576	0.017	ENST00000524571.2 ENST00000533852.2 ENST00000533513.1 ENST00000448228.2 ENST00000534520.1 ENST00000321602.8	FAM86B1	family with sequence similarity 86, member B1
chr8_+_118147498	0.016	ENST00000519688.1 ENST00000456015.2	SLC30A8	solute carrier family 30 (zinc transporter), member 8
chr18_+_11751466	0.012	ENST00000535121.1	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_+_23636992	0.011	ENST00000307471.3 ENST00000409765.1	CCDC126	coiled-coil domain containing 126
chr16_-_3285144	0.009	ENST00000431561.3 ENST00000396870.4	ZNF200	zinc finger protein 200
chr9_-_139658965	0.008	ENST00000316144.5	LCN15	lipocalin 15
chr6_+_159084188	0.007	ENST00000367081.3	SYTL3	synaptotagmin-like 3
chr10_+_105314881	0.007	ENST00000437579.1	NEURL	neuralized E3 ubiquitin protein ligase 1
chr12_+_109577202	0.006	ENST00000377848.3 ENST00000377854.5	ACACB	acetyl-CoA carboxylase beta
chr3_+_120626919	0.005	ENST00000273666.6 ENST00000471454.1 ENST00000472879.1 ENST00000497029.1 ENST00000492541.1	STXBP5L	syntaxin binding protein 5-like
chr1_-_42801540	0.004	ENST00000372573.1	FOXJ3	forkhead box J3
chr17_+_4675175	0.003	ENST00000270560.3	TM4SF5	transmembrane 4 L six family member 5
chr17_+_5389605	0.003	ENST00000576988.1 ENST00000576570.1 ENST00000573759.1	MIS12	MIS12 kinetochore complex component

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0052553	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.2	GO:1903461	Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1	0.4	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.2	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.0	0.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.2	GO:1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0	0.1	GO:0010157	response to chlorate(GO:0010157)
0.0	0.4	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.1	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.0	GO:0097114	NMDA glutamate receptor clustering(GO:0097114) retrograde trans-synaptic signaling(GO:0098917)
0.0	0.1	GO:0015862	uridine transport(GO:0015862)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0032797	SMN complex(GO:0032797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0070123	transforming growth factor beta receptor activity, type III(GO:0070123)
0.0	0.4	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.0	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0005119	smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0	0.2	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	SA_PROGRAMMED_CELL_DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME_INFLAMMASOMES	Genes involved in Inflammasomes

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