Motif ID: GGAAUGU

Z-value: 0.754


Mature miRNA associated with seed GGAAUGU:

NamemiRBase Accession
hsa-miR-1-3p MIMAT0000416
hsa-miR-206 MIMAT0000462
hsa-miR-613 MIMAT0003281



Activity profile for motif GGAAUGU.

activity profile for motif GGAAUGU


Sorted Z-values histogram for motif GGAAUGU

Sorted Z-values for motif GGAAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_76957214 1.664 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr15_+_39873268 0.969 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr2_+_70142189 0.721 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr10_-_28571015 0.546 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr12_+_104324112 0.492 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_+_100503643 0.483 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr1_+_26606608 0.481 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr3_-_134093395 0.442 ENST00000249883.5
AMOTL2
angiomotin like 2
chr2_-_43453734 0.399 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr12_-_109125285 0.378 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr3_+_171758344 0.376 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr7_+_129932974 0.366 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr16_+_69599861 0.365 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr15_-_60690163 0.352 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr2_-_232329186 0.341 ENST00000322723.4
NCL
nucleolin
chr17_+_38599693 0.340 ENST00000542955.1
ENST00000269593.4
IGFBP4

insulin-like growth factor binding protein 4

chr13_+_49550015 0.333 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr5_-_172756506 0.321 ENST00000265087.4
STC2
stanniocalcin 2
chr6_+_12290586 0.308 ENST00000379375.5
EDN1
endothelin 1
chr5_+_151151471 0.307 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr9_-_110251836 0.301 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chrX_-_20159934 0.298 ENST00000379593.1
ENST00000379607.5
EIF1AX

eukaryotic translation initiation factor 1A, X-linked

chr7_-_92463210 0.296 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr1_+_183441600 0.290 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr20_-_17662878 0.272 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr2_+_200775971 0.270 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr4_+_160188889 0.267 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr15_-_73076030 0.264 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr16_-_28222797 0.261 ENST00000569951.1
ENST00000565698.1
XPO6

exportin 6

chr14_-_91282726 0.261 ENST00000328459.6
ENST00000357056.2
TTC7B

tetratricopeptide repeat domain 7B

chr11_-_65769594 0.260 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD







eukaryotic translation initiation factor 1A domain containing







chr15_+_38544476 0.246 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr15_+_65134088 0.245 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr7_-_105925558 0.242 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr1_-_179198702 0.236 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_-_128392085 0.233 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr21_+_35445827 0.229 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr12_-_31945172 0.225 ENST00000340398.3
H3F3C
H3 histone, family 3C
chr5_+_56111361 0.224 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr1_+_64239657 0.223 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr1_-_150947343 0.223 ENST00000271688.6
ENST00000368954.5
CERS2

ceramide synthase 2

chr10_-_15210666 0.221 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr10_-_33623564 0.220 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr6_+_47445467 0.219 ENST00000359314.5
CD2AP
CD2-associated protein
chr16_-_18937726 0.217 ENST00000389467.3
ENST00000446231.2
SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr13_+_42846272 0.213 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr9_-_130742792 0.211 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr19_+_41725088 0.211 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr5_+_125935960 0.210 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr6_-_53409890 0.208 ENST00000229416.6
GCLC
glutamate-cysteine ligase, catalytic subunit
chr15_+_42066632 0.208 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr7_-_105029329 0.206 ENST00000393651.3
ENST00000460391.1
SRPK2

SRSF protein kinase 2

chr11_-_124670550 0.202 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr8_-_103876965 0.202 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr8_-_101965146 0.200 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta


chr13_-_45992473 0.199 ENST00000539591.1
ENST00000519676.1
ENST00000519547.1
SLC25A30


solute carrier family 25, member 30


chr14_+_20937538 0.199 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr1_+_160175117 0.195 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr5_+_61602055 0.192 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr20_+_49126881 0.184 ENST00000371621.3
ENST00000541713.1
PTPN1

protein tyrosine phosphatase, non-receptor type 1

chr13_-_79979919 0.183 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr18_+_29671812 0.182 ENST00000261593.3
ENST00000578914.1
RNF138

ring finger protein 138, E3 ubiquitin protein ligase

chrX_+_41192595 0.182 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr1_-_92351769 0.182 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr17_+_28804380 0.182 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1




golgi SNAP receptor complex member 1




chr20_-_52210368 0.181 ENST00000371471.2
ZNF217
zinc finger protein 217
chr12_-_102224704 0.179 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr1_-_211752073 0.177 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr12_+_79258547 0.177 ENST00000457153.2
SYT1
synaptotagmin I
chr1_-_95392635 0.176 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3


calponin 3, acidic


chr16_+_84853580 0.173 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
CRISPLD2




cysteine-rich secretory protein LCCL domain containing 2




chr15_+_65822756 0.173 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1




protein tyrosine phosphatase-like A domain containing 1




chr10_+_5454505 0.173 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr1_-_38273840 0.171 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr7_+_28452130 0.171 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr1_+_162467595 0.171 ENST00000538489.1
ENST00000489294.1
UHMK1

U2AF homology motif (UHM) kinase 1

chr1_+_112938803 0.168 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr1_-_78148324 0.166 ENST00000370801.3
ENST00000433749.1
ZZZ3

zinc finger, ZZ-type containing 3

chr20_-_30539773 0.164 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr14_+_51706886 0.164 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr12_+_69864129 0.162 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr18_+_3451646 0.160 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1


TGFB-induced factor homeobox 1


chr5_+_145583156 0.159 ENST00000265271.5
RBM27
RNA binding motif protein 27
chrX_+_118108571 0.158 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr10_+_98592009 0.158 ENST00000540664.1
ENST00000371103.3
LCOR

ligand dependent nuclear receptor corepressor

chr15_+_89631381 0.157 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr17_+_37026106 0.157 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr20_+_43104508 0.156 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr6_-_146135880 0.153 ENST00000237281.4
FBXO30
F-box protein 30
chr7_-_23053693 0.153 ENST00000409763.1
ENST00000409923.1
FAM126A

family with sequence similarity 126, member A

chr5_+_74632993 0.153 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr10_+_101419187 0.153 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr12_+_104850740 0.151 ENST00000547956.1
ENST00000549260.1
ENST00000303694.5
CHST11


carbohydrate (chondroitin 4) sulfotransferase 11


chr12_-_118797475 0.148 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr7_-_105517021 0.148 ENST00000318724.4
ENST00000419735.3
ATXN7L1

ataxin 7-like 1

chr6_-_154831779 0.147 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr1_-_154600421 0.145 ENST00000368471.3
ENST00000292205.5
ADAR

adenosine deaminase, RNA-specific

chr11_-_76091986 0.145 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr3_+_51575596 0.144 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr20_-_656437 0.143 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr3_-_195163803 0.140 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr3_-_123603137 0.138 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr13_+_42622781 0.137 ENST00000337343.4
ENST00000261491.5
ENST00000379274.2
DGKH


diacylglycerol kinase, eta


chr1_+_167691191 0.136 ENST00000392121.3
ENST00000474859.1
MPZL1

myelin protein zero-like 1

chr22_+_45559722 0.136 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50





nucleoporin 50kDa





chr18_+_59854480 0.135 ENST00000256858.6
ENST00000398130.2
KIAA1468

KIAA1468

chr21_-_43430440 0.135 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21





zinc finger and BTB domain containing 21





chr10_-_60027642 0.134 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr14_+_74111578 0.133 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr10_+_25463951 0.133 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr15_+_59063478 0.133 ENST00000559228.1
ENST00000450403.2
FAM63B

family with sequence similarity 63, member B

chr8_-_41909496 0.133 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A




K(lysine) acetyltransferase 6A




chr4_-_99851766 0.132 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr9_+_130830451 0.131 ENST00000373068.2
ENST00000373069.5
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr6_+_157802165 0.130 ENST00000414563.2
ENST00000359775.5
ZDHHC14

zinc finger, DHHC-type containing 14

chr7_-_5570229 0.130 ENST00000331789.5
ACTB
actin, beta
chr4_+_44680429 0.130 ENST00000281543.5
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr17_+_45973516 0.129 ENST00000376741.4
SP2
Sp2 transcription factor
chr16_-_71758602 0.129 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr19_-_6424783 0.127 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr22_+_33197683 0.127 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chrX_-_48901012 0.127 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr11_-_796197 0.126 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22


solute carrier family 25 (mitochondrial carrier: glutamate), member 22


chr11_+_58346584 0.125 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chrX_-_129402857 0.124 ENST00000447817.1
ENST00000370978.4
ZNF280C

zinc finger protein 280C

chr14_+_56046914 0.123 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
KTN1



kinectin 1 (kinesin receptor)



chr2_-_96874553 0.121 ENST00000337288.5
ENST00000443962.1
STARD7

StAR-related lipid transfer (START) domain containing 7

chr1_-_35658736 0.120 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr4_-_10118469 0.119 ENST00000499869.2
WDR1
WD repeat domain 1
chr7_+_32535060 0.117 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
AVL9


AVL9 homolog (S. cerevisiase)


chr15_+_59279851 0.117 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111


ring finger protein 111


chr2_+_191745560 0.116 ENST00000338435.4
GLS
glutaminase
chr8_+_124780672 0.115 ENST00000521166.1
ENST00000334705.7
FAM91A1

family with sequence similarity 91, member A1

chr1_-_27816556 0.113 ENST00000536657.1
WASF2
WAS protein family, member 2
chr3_-_72496035 0.113 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr12_-_100536608 0.113 ENST00000356828.3
ENST00000279907.7
UHRF1BP1L

UHRF1 binding protein 1-like

chr2_-_39664405 0.112 ENST00000341681.5
ENST00000263881.3
MAP4K3

mitogen-activated protein kinase kinase kinase kinase 3

chr2_+_36582857 0.112 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr1_-_175161890 0.112 ENST00000545251.2
ENST00000423313.1
KIAA0040

KIAA0040

chr7_+_138916231 0.112 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chr2_+_134877740 0.112 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr15_-_101792137 0.111 ENST00000254190.3
CHSY1
chondroitin sulfate synthase 1
chr4_-_1857954 0.111 ENST00000302787.2
LETM1
leucine zipper-EF-hand containing transmembrane protein 1
chr1_-_39325431 0.109 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr16_-_3493528 0.106 ENST00000301744.4
ZNF597
zinc finger protein 597
chr9_-_36400213 0.105 ENST00000259605.6
ENST00000353739.4
RNF38

ring finger protein 38

chr20_-_634000 0.105 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr12_-_42538657 0.105 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr1_+_113161778 0.105 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr19_+_16187085 0.105 ENST00000300933.4
TPM4
tropomyosin 4
chr19_+_7459998 0.104 ENST00000319670.9
ENST00000599752.1
ARHGEF18

Rho/Rac guanine nucleotide exchange factor (GEF) 18

chr6_-_105307711 0.104 ENST00000519645.1
ENST00000262903.4
ENST00000369125.2
HACE1


HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1


chr10_+_76586348 0.103 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr2_+_24714729 0.102 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr2_+_60983361 0.102 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr12_-_46766577 0.101 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr17_-_1733114 0.099 ENST00000305513.7
SMYD4
SET and MYND domain containing 4
chr3_-_42846021 0.098 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr2_+_39893043 0.098 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr14_-_36278412 0.096 ENST00000389698.3
ENST00000258840.6
RALGAPA1

Ral GTPase activating protein, alpha subunit 1 (catalytic)

chr17_+_38375574 0.094 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr15_-_48470558 0.093 ENST00000324324.7
MYEF2
myelin expression factor 2
chr1_-_180991978 0.093 ENST00000542060.1
ENST00000258301.5
STX6

syntaxin 6

chr2_+_232573208 0.093 ENST00000409115.3
PTMA
prothymosin, alpha
chr9_+_100745615 0.092 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr20_-_62199427 0.091 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr1_+_206557366 0.090 ENST00000414007.1
ENST00000419187.2
SRGAP2

SLIT-ROBO Rho GTPase activating protein 2

chr9_+_115983808 0.090 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr20_-_50159198 0.090 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2


chr12_-_44200052 0.089 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1




twinfilin actin-binding protein 1




chr1_-_159893507 0.088 ENST00000368096.1
TAGLN2
transgelin 2
chr15_-_42840961 0.088 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57



leucine rich repeat containing 57



chr14_-_92506371 0.088 ENST00000267622.4
TRIP11
thyroid hormone receptor interactor 11
chr5_-_94620239 0.088 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_4897632 0.087 ENST00000262376.6
UBN1
ubinuclein 1
chr2_-_55844720 0.087 ENST00000345102.5
ENST00000272313.5
ENST00000407823.3
SMEK2


SMEK homolog 2, suppressor of mek1 (Dictyostelium)


chr16_+_69458428 0.086 ENST00000512062.1
ENST00000307892.8
CYB5B

cytochrome b5 type B (outer mitochondrial membrane)

chr2_-_9770706 0.086 ENST00000381844.4
YWHAQ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr6_-_86352642 0.085 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr3_+_127771212 0.085 ENST00000243253.3
ENST00000481210.1
SEC61A1

Sec61 alpha 1 subunit (S. cerevisiae)

chr2_+_45878790 0.085 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr3_+_19988566 0.084 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chrX_+_12993202 0.084 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chrX_-_19988382 0.083 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23


chromosome X open reading frame 23


chr5_+_89770696 0.083 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr2_+_202899310 0.082 ENST00000286201.1
FZD7
frizzled family receptor 7
chr19_+_36706024 0.082 ENST00000443387.2
ZNF146
zinc finger protein 146
chr11_+_69455855 0.081 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr8_-_38239732 0.081 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1



Wolf-Hirschhorn syndrome candidate 1-like 1



chr10_-_126849068 0.080 ENST00000494626.2
ENST00000337195.5
CTBP2

C-terminal binding protein 2

chr19_-_12834739 0.080 ENST00000589337.1
ENST00000425528.1
ENST00000441499.1
ENST00000588216.1
TNPO2



transportin 2



chr17_+_60536002 0.079 ENST00000582809.1
TLK2
tousled-like kinase 2
chr20_+_18488137 0.079 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B



Sec23 homolog B (S. cerevisiae)



chr2_-_26101374 0.077 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr12_-_58146048 0.076 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr11_-_85780086 0.075 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr6_-_139695757 0.075 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr6_-_8435706 0.075 ENST00000379660.4
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr12_-_76953284 0.075 ENST00000547544.1
ENST00000393249.2
OSBPL8

oxysterol binding protein-like 8

chr19_-_4066890 0.074 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.2 0.5 GO:0031247 actin rod assembly(GO:0031247)
0.2 1.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.4 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.2 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.2 GO:1905045 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 0.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:0001743 optic placode formation(GO:0001743)
0.1 0.2 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.2 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.0 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.0 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0033643 host cell part(GO:0033643)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.0 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo