Motif ID: GFI1B

Z-value: 0.433


Transcription factors associated with GFI1B:

Gene SymbolEntrez IDGene Name
GFI1B ENSG00000165702.8 GFI1B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1Bhg19_v2_chr9_+_135854091_135854159-0.088.5e-01Click!


Activity profile for motif GFI1B.

activity profile for motif GFI1B


Sorted Z-values histogram for motif GFI1B

Sorted Z-values for motif GFI1B



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_165555200 0.966 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr11_-_94964354 0.522 ENST00000536441.1
SESN3
sestrin 3
chr20_+_52105495 0.501 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_+_233390863 0.384 ENST00000449596.1
ENST00000543200.1
CHRND

cholinergic receptor, nicotinic, delta (muscle)

chr1_+_211813019 0.330 ENST00000430123.1
RP11-354K1.1
RP11-354K1.1
chr15_-_90645679 0.320 ENST00000539790.1
ENST00000559482.1
ENST00000330062.3
IDH2


isocitrate dehydrogenase 2 (NADP+), mitochondrial


chr7_-_138363824 0.310 ENST00000419765.3
SVOPL
SVOP-like
chr17_-_26694979 0.308 ENST00000438614.1
VTN
vitronectin
chr12_+_54447637 0.304 ENST00000609810.1
ENST00000430889.2
HOXC4
HOXC4
homeobox C4
Homeobox protein Hox-C4
chr17_-_26695013 0.282 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr19_-_10687907 0.274 ENST00000589348.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr13_+_98795664 0.265 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr4_+_41362796 0.256 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr9_-_100954910 0.250 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr12_-_6602955 0.243 ENST00000543703.1
MRPL51
mitochondrial ribosomal protein L51
chr17_-_33759509 0.238 ENST00000304905.5
SLFN12
schlafen family member 12
chr12_+_50017327 0.238 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_+_109102652 0.236 ENST00000370035.3
ENST00000405454.1
FAM102B

family with sequence similarity 102, member B

chr8_+_87354945 0.224 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr4_-_112993808 0.220 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr12_+_50017184 0.216 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr3_+_154801678 0.212 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr14_+_72052983 0.209 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr20_-_57607347 0.208 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
ATP5E


ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit


chrX_+_57618269 0.206 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr4_-_186696561 0.199 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr19_+_17337473 0.196 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr2_+_219724544 0.191 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr1_+_162602244 0.191 ENST00000367922.3
ENST00000367921.3
DDR2

discoidin domain receptor tyrosine kinase 2

chr3_-_119813264 0.185 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr19_-_45681482 0.185 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A



trafficking protein particle complex 6A



chr2_-_190044480 0.184 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr7_+_66093908 0.183 ENST00000443322.1
ENST00000449064.1
KCTD7

potassium channel tetramerization domain containing 7

chr7_+_134576151 0.180 ENST00000393118.2
CALD1
caldesmon 1
chr12_+_6603253 0.176 ENST00000382457.4
ENST00000545962.1
NCAPD2

non-SMC condensin I complex, subunit D2

chr6_-_56707943 0.176 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr3_-_149688655 0.175 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2




profilin 2




chr10_+_124221036 0.173 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr4_-_88244049 0.172 ENST00000328546.4
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr5_+_150591678 0.171 ENST00000523466.1
GM2A
GM2 ganglioside activator
chr4_-_185694872 0.171 ENST00000505492.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_-_95538492 0.168 ENST00000370205.5
ALG14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr18_-_48723690 0.166 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr4_-_88244010 0.164 ENST00000302219.6
HSD17B13
hydroxysteroid (17-beta) dehydrogenase 13
chr5_-_146461027 0.160 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_-_47134085 0.159 ENST00000371937.4
ENST00000574428.1
ENST00000329231.4
ATPAF1


ATP synthase mitochondrial F1 complex assembly factor 1


chr4_-_186697044 0.155 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr16_+_69221028 0.155 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr1_-_74663825 0.155 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3


leucine-rich repeats and IQ motif containing 3


chr17_-_56595196 0.154 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4


myotubularin related protein 4


chr13_+_113623509 0.154 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr4_+_154125565 0.152 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr6_-_133119649 0.150 ENST00000367918.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chrX_+_77359726 0.150 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chr3_+_154801312 0.149 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr1_+_210406121 0.147 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr12_+_117176090 0.146 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2


ring finger protein, transmembrane 2


chr2_+_171785012 0.146 ENST00000234160.4
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr16_-_30597000 0.144 ENST00000470110.1
ENST00000395216.2
ZNF785

zinc finger protein 785

chr14_-_53417732 0.144 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2



chrX_+_77359671 0.140 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chr3_+_119814070 0.140 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr12_-_54779511 0.139 ENST00000551109.1
ENST00000546970.1
ZNF385A

zinc finger protein 385A

chr17_+_36858694 0.137 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr14_-_64194745 0.136 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr1_-_47134101 0.136 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr11_+_71791849 0.135 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT




leucine rich transmembrane and O-methyltransferase domain containing




chr4_-_140216948 0.133 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_10736183 0.132 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
SLC44A2


solute carrier family 44 (choline transporter), member 2


chr1_+_840205 0.131 ENST00000607769.1
RP11-54O7.16
RP11-54O7.16
chr6_-_56708459 0.131 ENST00000370788.2
DST
dystonin
chr6_+_46620676 0.131 ENST00000371347.5
ENST00000411689.2
SLC25A27

solute carrier family 25, member 27

chr1_-_220220000 0.131 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr2_+_85646054 0.130 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr16_+_12059091 0.129 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_21910775 0.129 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr2_-_85788652 0.127 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr1_+_164528866 0.127 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr11_+_74699703 0.126 ENST00000529024.1
ENST00000544263.1
NEU3

sialidase 3 (membrane sialidase)

chr5_-_137475071 0.124 ENST00000265191.2
NME5
NME/NM23 family member 5
chr1_+_244816237 0.123 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr4_-_186696425 0.122 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr19_+_51774540 0.122 ENST00000600813.1
CTD-3187F8.11
CTD-3187F8.11
chr8_+_75736761 0.121 ENST00000260113.2
PI15
peptidase inhibitor 15
chr12_-_31881944 0.120 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
AMN1




antagonist of mitotic exit network 1 homolog (S. cerevisiae)




chr6_+_26521948 0.116 ENST00000411553.1
HCG11
HLA complex group 11 (non-protein coding)
chr6_+_21593972 0.115 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr12_+_117176113 0.115 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr1_-_144364246 0.114 ENST00000540273.1
PPIAL4B
peptidylprolyl isomerase A (cyclophilin A)-like 4B
chr11_+_71791693 0.113 ENST00000289488.2
ENST00000447974.1
LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr12_+_93861264 0.113 ENST00000549982.1
ENST00000361630.2
MRPL42

mitochondrial ribosomal protein L42

chr11_+_101785727 0.112 ENST00000263468.8
KIAA1377
KIAA1377
chr1_+_164528437 0.111 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr7_-_37382360 0.110 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr12_+_124155652 0.109 ENST00000426174.2
ENST00000303372.5
TCTN2

tectonic family member 2

chr12_+_44229846 0.109 ENST00000551577.1
ENST00000266534.3
TMEM117

transmembrane protein 117

chr1_-_143767881 0.107 ENST00000419275.1
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr11_+_118272328 0.107 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr19_+_2867325 0.107 ENST00000307635.2
ENST00000586426.1
ZNF556

zinc finger protein 556

chr3_-_93781750 0.106 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr18_+_77905894 0.106 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
AC139100.2


Uncharacterized protein


chr1_-_220219775 0.106 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr7_+_134576317 0.105 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr11_+_5617976 0.105 ENST00000445329.1
TRIM6
tripartite motif containing 6
chr2_-_85788605 0.105 ENST00000233838.4
GGCX
gamma-glutamyl carboxylase
chr11_+_5617330 0.104 ENST00000278302.5
ENST00000424369.1
ENST00000507320.1
ENST00000380107.1
TRIM6



tripartite motif containing 6



chr17_-_5321549 0.103 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr10_-_129924611 0.103 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr1_-_148202536 0.102 ENST00000544708.1
PPIAL4D
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr10_-_129924468 0.102 ENST00000368653.3
MKI67
marker of proliferation Ki-67
chr4_-_186696636 0.101 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr15_-_38519066 0.100 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1

RP11-346D14.1

chr1_-_111970353 0.100 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr1_+_149553003 0.099 ENST00000369222.3
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr7_-_86849025 0.097 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr18_+_11857439 0.095 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_-_86848933 0.095 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr19_+_51774520 0.095 ENST00000595566.1
ENST00000594261.1
CTD-3187F8.11

CTD-3187F8.11

chr1_+_162601774 0.093 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr1_-_28559502 0.093 ENST00000263697.4
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr4_-_186696515 0.091 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr1_-_115300579 0.091 ENST00000358528.4
ENST00000525132.1
CSDE1

cold shock domain containing E1, RNA-binding

chr1_-_147955419 0.091 ENST00000539781.1
PPIAL4A
peptidylprolyl isomerase A (cyclophilin A)-like 4A
chr6_+_46620705 0.091 ENST00000452689.2
SLC25A27
solute carrier family 25, member 27
chr12_-_13105081 0.090 ENST00000541128.1
GPRC5D
G protein-coupled receptor, family C, group 5, member D
chr4_+_26165074 0.089 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_23751189 0.089 ENST00000374601.3
ENST00000450454.2
TCEA3

transcription elongation factor A (SII), 3

chr12_+_48876275 0.089 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr16_-_30596818 0.088 ENST00000567773.1
ZNF785
zinc finger protein 785
chr1_-_54637997 0.088 ENST00000536061.1
AL357673.1
CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr8_-_49834299 0.087 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr20_+_32254286 0.087 ENST00000330271.4
ACTL10
actin-like 10
chr7_+_39663061 0.086 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr4_-_156875003 0.086 ENST00000433477.3
CTSO
cathepsin O
chr12_+_100967533 0.085 ENST00000550295.1
GAS2L3
growth arrest-specific 2 like 3
chr1_+_15943995 0.084 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr11_+_5618029 0.083 ENST00000515022.1
ENST00000506134.1
TRIM6

tripartite motif containing 6

chr21_+_45705752 0.082 ENST00000291582.5
AIRE
autoimmune regulator
chr11_+_71791803 0.081 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr1_+_39796810 0.080 ENST00000289893.4
MACF1
microtubule-actin crosslinking factor 1
chr8_-_28965684 0.080 ENST00000523130.1
KIF13B
kinesin family member 13B
chr19_-_17571722 0.079 ENST00000301944.2
NXNL1
nucleoredoxin-like 1
chr13_-_27745936 0.079 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr8_-_49833978 0.079 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr14_-_80677970 0.079 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr12_+_48513570 0.079 ENST00000551804.1
PFKM
phosphofructokinase, muscle
chr1_-_115300592 0.078 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
CSDE1






cold shock domain containing E1, RNA-binding






chr1_+_244816371 0.078 ENST00000263831.7
DESI2
desumoylating isopeptidase 2
chr7_+_79765071 0.078 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr14_+_96039882 0.077 ENST00000556346.1
ENST00000553785.1
RP11-1070N10.4

RP11-1070N10.4

chr15_+_32933866 0.077 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
SCG5



secretogranin V (7B2 protein)



chr10_+_97471508 0.077 ENST00000453258.2
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr17_+_49230897 0.076 ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
NME2


NME1




NME1-NME2

NME/NM23 nucleoside diphosphate kinase 2


NME/NM23 nucleoside diphosphate kinase 1




NME1-NME2 readthrough

chr1_+_151009035 0.076 ENST00000368931.3
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr9_-_95056010 0.075 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr13_-_76111945 0.075 ENST00000355801.4
ENST00000406936.3
COMMD6

COMM domain containing 6

chr12_-_54071181 0.075 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr18_+_43914159 0.075 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165


ring finger protein 165


chr2_+_233877324 0.074 ENST00000409905.1
AC106876.2
Uncharacterized protein
chr21_-_43916433 0.074 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr10_-_102279586 0.074 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B


SEC31 homolog B (S. cerevisiae)


chr2_+_242295658 0.073 ENST00000264042.3
ENST00000545004.1
ENST00000373287.4
FARP2


FERM, RhoGEF and pleckstrin domain protein 2


chr1_-_115301235 0.073 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr1_-_21377383 0.073 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_54683419 0.073 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_-_23886285 0.072 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr10_+_45455207 0.072 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
RASSF4



Ras association (RalGDS/AF-6) domain family member 4



chr16_+_19183671 0.072 ENST00000562711.2
SYT17
synaptotagmin XVII
chr11_-_46113756 0.072 ENST00000531959.1
PHF21A
PHD finger protein 21A
chr4_-_186733119 0.071 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_201754135 0.071 ENST00000409357.1
ENST00000409129.2
NIF3L1

NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)

chr12_+_100967420 0.071 ENST00000266754.5
ENST00000547754.1
GAS2L3

growth arrest-specific 2 like 3

chr7_+_44040488 0.071 ENST00000258704.3
SPDYE1
speedy/RINGO cell cycle regulator family member E1
chr15_-_90456156 0.070 ENST00000357484.5
C15orf38
chromosome 15 open reading frame 38
chr3_-_49466686 0.070 ENST00000273598.3
ENST00000436744.2
NICN1

nicolin 1

chr2_+_219472637 0.069 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr16_+_12058961 0.069 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr19_-_43708378 0.068 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr19_-_16008880 0.068 ENST00000011989.7
ENST00000221700.6
CYP4F2

cytochrome P450, family 4, subfamily F, polypeptide 2

chr1_+_203651937 0.067 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr6_-_149867122 0.067 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr8_+_82066514 0.067 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2

RP11-1149M10.2

chr6_-_116381918 0.066 ENST00000606080.1
FRK
fyn-related kinase
chr12_-_95397442 0.066 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12


chr2_+_201754050 0.066 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3L1




NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)




chr2_+_27799389 0.065 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr8_+_62200509 0.065 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1


clavesin 1


chr22_+_19466980 0.063 ENST00000407835.1
ENST00000438587.1
CDC45

cell division cycle 45

chr2_+_201994208 0.063 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_-_149688896 0.063 ENST00000239940.7
PFN2
profilin 2
chr6_-_131384412 0.062 ENST00000445890.2
ENST00000368128.2
ENST00000337057.3
EPB41L2


erythrocyte membrane protein band 4.1-like 2


chr6_-_131384373 0.062 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
EPB41L2


erythrocyte membrane protein band 4.1-like 2


chr6_-_131384347 0.061 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_+_55417499 0.061 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1



natural cytotoxicity triggering receptor 1



chr7_+_130020932 0.061 ENST00000484324.1
CPA1
carboxypeptidase A1 (pancreatic)
chr2_-_110371720 0.061 ENST00000356688.4
SEPT10
septin 10
chr6_-_46620522 0.061 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr1_+_10290822 0.060 ENST00000377083.1
KIF1B
kinesin family member 1B
chr6_-_116601044 0.060 ENST00000368608.3
TSPYL1
TSPY-like 1
chr4_-_186732892 0.060 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0009820 alkaloid metabolic process(GO:0009820)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.2 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0032304 pressure natriuresis(GO:0003095) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0002461 tolerance induction dependent upon immune response(GO:0002461) regulation of thymocyte migration(GO:2000410)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.0 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0052870 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.0 GO:0005503 all-trans retinal binding(GO:0005503)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane