Motif ID: GFI1

Z-value: 0.720


Transcription factors associated with GFI1:

Gene SymbolEntrez IDGene Name
GFI1 ENSG00000162676.7 GFI1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1hg19_v2_chr1_-_92949505_929495430.215.8e-01Click!


Activity profile for motif GFI1.

activity profile for motif GFI1


Sorted Z-values histogram for motif GFI1

Sorted Z-values for motif GFI1



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39780634 0.736 ENST00000577817.2
KRT17
keratin 17
chr17_-_39780819 0.711 ENST00000311208.8
KRT17
keratin 17
chr17_-_39781054 0.681 ENST00000463128.1
KRT17
keratin 17
chr8_+_70378852 0.671 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr1_-_230513367 0.591 ENST00000321327.2
ENST00000525115.1
PGBD5

piggyBac transposable element derived 5

chr11_-_8892900 0.497 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
ST5






suppression of tumorigenicity 5






chr11_+_34642656 0.463 ENST00000257831.3
ENST00000450654.2
EHF

ets homologous factor

chr8_-_57232656 0.426 ENST00000396721.2
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr2_+_189839046 0.378 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chr19_+_47813110 0.365 ENST00000355085.3
C5AR1
complement component 5a receptor 1
chr7_+_23636992 0.353 ENST00000307471.3
ENST00000409765.1
CCDC126

coiled-coil domain containing 126

chr17_-_26694979 0.349 ENST00000438614.1
VTN
vitronectin
chr15_+_49715449 0.348 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr15_+_49715293 0.347 ENST00000267843.4
ENST00000560270.1
FGF7

fibroblast growth factor 7

chr17_-_26695013 0.346 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr7_+_114055052 0.317 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr5_+_36608422 0.280 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_147232669 0.274 ENST00000369237.1
GJA5
gap junction protein, alpha 5, 40kDa
chr11_-_94964354 0.271 ENST00000536441.1
SESN3
sestrin 3
chr5_-_111091948 0.270 ENST00000447165.2
NREP
neuronal regeneration related protein
chr5_+_36608280 0.268 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_136172820 0.262 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr9_+_34989638 0.259 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr2_-_142888573 0.254 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr12_+_96337061 0.236 ENST00000266736.2
AMDHD1
amidohydrolase domain containing 1
chr11_-_82746587 0.230 ENST00000528379.1
ENST00000534103.1
RAB30

RAB30, member RAS oncogene family

chr2_+_85360499 0.221 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr8_+_70379072 0.220 ENST00000529134.1
SULF1
sulfatase 1
chr6_+_26440700 0.220 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr4_-_119759795 0.219 ENST00000419654.2
SEC24D
SEC24 family member D
chr16_+_19183671 0.219 ENST00000562711.2
SYT17
synaptotagmin XVII
chr11_-_66675371 0.216 ENST00000393955.2
PC
pyruvate carboxylase
chr11_+_1049862 0.212 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr22_+_27068766 0.205 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5



CTA-211A9.5



chr11_-_82782861 0.204 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr19_-_55660561 0.203 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1






troponin T type 1 (skeletal, slow)






chr4_+_86749045 0.199 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_110612323 0.199 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr11_+_72281681 0.196 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr11_+_20044375 0.189 ENST00000525322.1
ENST00000530408.1
NAV2

neuron navigator 2

chr9_+_2158443 0.185 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2



SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2



chr21_-_47648665 0.183 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS




lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)




chr3_+_108321623 0.182 ENST00000497905.1
ENST00000463306.1
DZIP3

DAZ interacting zinc finger protein 3

chr19_-_18391708 0.181 ENST00000600972.1
JUND
jun D proto-oncogene
chr5_-_90679145 0.179 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr5_-_150284351 0.176 ENST00000427179.1
ZNF300
zinc finger protein 300
chr17_-_18266818 0.176 ENST00000583780.1
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr11_+_36397528 0.176 ENST00000311599.5
ENST00000378867.3
PRR5L

proline rich 5 like

chr5_-_150284532 0.174 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
ZNF300



zinc finger protein 300



chr5_+_41925325 0.172 ENST00000296812.2
ENST00000281623.3
ENST00000509134.1
FBXO4


F-box protein 4


chr18_+_21452964 0.171 ENST00000587184.1
LAMA3
laminin, alpha 3
chr12_-_110011288 0.169 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr3_+_107364769 0.165 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX


bobby sox homolog (Drosophila)


chr11_-_61124711 0.165 ENST00000536915.1
CYB561A3
cytochrome b561 family, member A3
chr9_+_2158485 0.164 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2


chr17_+_73780852 0.164 ENST00000589666.1
UNK
unkempt family zinc finger
chr3_+_99833755 0.163 ENST00000489081.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chr18_+_21452804 0.161 ENST00000269217.6
LAMA3
laminin, alpha 3
chr1_-_54879140 0.160 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr1_+_64058939 0.160 ENST00000371084.3
PGM1
phosphoglucomutase 1
chr12_-_58212487 0.159 ENST00000549994.1
AVIL
advillin
chr20_-_33732952 0.157 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr19_+_50353944 0.155 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1



prostate tumor overexpressed 1



chr11_-_8892464 0.154 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5




suppression of tumorigenicity 5




chr22_+_31518938 0.153 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr11_-_31832581 0.151 ENST00000379111.2
PAX6
paired box 6
chr11_+_20044096 0.151 ENST00000533917.1
NAV2
neuron navigator 2
chr1_-_74663825 0.151 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3


leucine-rich repeats and IQ motif containing 3


chr8_+_132320792 0.151 ENST00000519695.1
ENST00000524275.1
CTD-2501M5.1

CTD-2501M5.1

chr11_-_31832862 0.149 ENST00000379115.4
PAX6
paired box 6
chr12_+_44229846 0.148 ENST00000551577.1
ENST00000266534.3
TMEM117

transmembrane protein 117

chr11_-_31832785 0.147 ENST00000241001.8
PAX6
paired box 6
chr10_+_72972281 0.143 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr2_-_61389168 0.142 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1

RP11-493E12.1

chr10_+_24755416 0.142 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr6_+_31982539 0.142 ENST00000435363.2
ENST00000425700.2
C4B

complement component 4B (Chido blood group)

chr15_+_92397051 0.138 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr2_+_219724544 0.138 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr15_-_52587945 0.138 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C


myosin VC


chr16_-_70323422 0.137 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr21_+_17566643 0.136 ENST00000419952.1
ENST00000445461.2
LINC00478

long intergenic non-protein coding RNA 478

chr5_+_37379314 0.134 ENST00000265107.4
ENST00000504564.1
WDR70

WD repeat domain 70

chr19_-_3761673 0.132 ENST00000316757.3
APBA3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr4_-_69083720 0.131 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr17_-_79895097 0.131 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1




pyrroline-5-carboxylate reductase 1




chr1_+_153940346 0.131 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4



cAMP responsive element binding protein 3-like 4



chr19_-_9092018 0.129 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr9_+_131181798 0.129 ENST00000420512.1
CERCAM
cerebral endothelial cell adhesion molecule
chr6_+_31949801 0.129 ENST00000428956.2
ENST00000498271.1
C4A

complement component 4A (Rodgers blood group)

chr8_-_49834299 0.129 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr5_+_66254698 0.128 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr1_+_153940713 0.127 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4


cAMP responsive element binding protein 3-like 4


chr5_+_118690466 0.126 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_+_107364683 0.126 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr10_+_124221036 0.125 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr7_+_123488124 0.124 ENST00000476325.1
HYAL4
hyaluronoglucosaminidase 4
chr9_+_131181393 0.123 ENST00000447915.1
CERCAM
cerebral endothelial cell adhesion molecule
chr17_+_19281787 0.122 ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7
chr15_+_92396920 0.121 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr2_-_10978103 0.121 ENST00000404824.2
PDIA6
protein disulfide isomerase family A, member 6
chr8_-_49833978 0.121 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr20_-_62203808 0.120 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chrX_-_73511908 0.119 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr12_-_10542617 0.119 ENST00000240618.6
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr19_+_36602104 0.119 ENST00000585332.1
ENST00000262637.4
OVOL3

ovo-like zinc finger 3

chr18_-_30050395 0.119 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr19_+_36236491 0.117 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr17_-_1395954 0.116 ENST00000359786.5
MYO1C
myosin IC
chr11_-_84634447 0.116 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr17_-_1418972 0.116 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr9_-_34376851 0.115 ENST00000297625.7
KIAA1161
KIAA1161
chr7_-_27187393 0.114 ENST00000222728.3
HOXA6
homeobox A6
chr2_-_99485825 0.112 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr4_+_86748898 0.112 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr22_+_24204375 0.111 ENST00000433835.3
AP000350.10
Uncharacterized protein
chr13_+_113623509 0.111 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr4_-_185747188 0.110 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1



acyl-CoA synthetase long-chain family member 1



chr15_-_42500351 0.110 ENST00000348544.4
ENST00000318006.5
VPS39

vacuolar protein sorting 39 homolog (S. cerevisiae)

chr11_-_31832685 0.110 ENST00000438681.1
PAX6
paired box 6
chr3_-_112329110 0.109 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr6_+_80816342 0.108 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB


branched chain keto acid dehydrogenase E1, beta polypeptide


chr4_+_89299885 0.107 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chr17_-_18266797 0.106 ENST00000316694.3
ENST00000539052.1
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr2_+_183943464 0.105 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr12_+_110011571 0.105 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr6_-_146057144 0.104 ENST00000367519.3
EPM2A
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr1_+_153940741 0.104 ENST00000431292.1
CREB3L4
cAMP responsive element binding protein 3-like 4
chr11_-_14380664 0.104 ENST00000545643.1
ENST00000256196.4
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr17_-_18266765 0.104 ENST00000354098.3
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr19_+_36236514 0.103 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr6_-_27835357 0.102 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr18_+_3448455 0.102 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr11_-_84634217 0.102 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_74663896 0.102 ENST00000370891.2
ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
TNNI3K
FPGT





FPGT-TNNI3K




TNNI3 interacting kinase
fucose-1-phosphate guanylyltransferase





FPGT-TNNI3K readthrough




chr17_-_18266660 0.101 ENST00000582653.1
ENST00000352886.6
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr11_-_72433346 0.101 ENST00000334211.8
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_165414414 0.100 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr7_+_43803790 0.100 ENST00000424330.1
BLVRA
biliverdin reductase A
chrX_+_49832231 0.099 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr21_-_40033618 0.099 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG


v-ets avian erythroblastosis virus E26 oncogene homolog


chr19_-_49140692 0.099 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr1_+_165600436 0.099 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3


microsomal glutathione S-transferase 3


chr8_+_52730143 0.098 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr11_+_32112431 0.097 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr17_-_202579 0.096 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chrX_+_53449805 0.096 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr6_+_42984723 0.096 ENST00000332245.8
KLHDC3
kelch domain containing 3
chr5_+_79783788 0.096 ENST00000282226.4
FAM151B
family with sequence similarity 151, member B
chr6_-_44400720 0.095 ENST00000595057.1
AL133262.1
AL133262.1
chrX_+_102611373 0.095 ENST00000372661.3
ENST00000372656.3
WBP5

WW domain binding protein 5

chr19_+_19303008 0.095 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK




regulatory factor X-associated ankyrin-containing protein




chr1_+_243419306 0.094 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr19_-_49140609 0.094 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr22_-_42322795 0.093 ENST00000291232.3
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr2_+_157292859 0.092 ENST00000438166.2
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr19_+_50354430 0.091 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr6_+_146056706 0.091 ENST00000603994.1
RP3-466P17.1
RP3-466P17.1
chr6_-_41040268 0.090 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
OARD1





O-acyl-ADP-ribose deacylase 1





chr15_+_99433570 0.089 ENST00000558898.1
IGF1R
insulin-like growth factor 1 receptor
chr11_+_117049445 0.089 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr12_+_7941989 0.088 ENST00000229307.4
NANOG
Nanog homeobox
chr17_+_37856253 0.088 ENST00000540147.1
ENST00000584450.1
ERBB2

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

chr19_+_41103063 0.087 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chrX_-_47004878 0.087 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr12_+_113354341 0.087 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr4_+_154073469 0.086 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr8_+_58890917 0.086 ENST00000522992.1
RP11-1112C15.1
RP11-1112C15.1
chr1_+_9299895 0.086 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_+_176987088 0.085 ENST00000249499.6
HOXD9
homeobox D9
chr2_+_239335636 0.084 ENST00000409297.1
ASB1
ankyrin repeat and SOCS box containing 1
chr20_+_23168759 0.084 ENST00000411595.1
RP4-737E23.2
RP4-737E23.2
chr4_+_89299994 0.083 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_-_8093471 0.081 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr17_-_79895154 0.081 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1



pyrroline-5-carboxylate reductase 1



chr17_+_79495397 0.081 ENST00000417245.2
ENST00000334850.7
FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chr16_-_29479154 0.081 ENST00000549950.1
RP11-345J4.3
Uncharacterized protein
chr3_-_110612059 0.080 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr6_-_10412600 0.080 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_-_102279586 0.080 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31B


SEC31 homolog B (S. cerevisiae)


chr12_-_104443890 0.080 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2


glycosyltransferase 8 domain containing 2


chr9_+_133710453 0.080 ENST00000318560.5
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr2_+_66662690 0.080 ENST00000488550.1
MEIS1
Meis homeobox 1
chrX_-_48980098 0.080 ENST00000156109.5
GPKOW
G patch domain and KOW motifs
chr19_+_4402659 0.080 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr6_+_62284008 0.079 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr6_+_21593972 0.079 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr22_-_42343117 0.079 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr7_-_112579673 0.079 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr11_+_123986069 0.079 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A





von Willebrand factor A domain containing 5A





chr11_-_60720002 0.078 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr7_-_120498357 0.077 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr1_+_46713404 0.077 ENST00000371975.4
ENST00000469835.1
RAD54L

RAD54-like (S. cerevisiae)

chr19_+_50354462 0.077 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr1_+_62439037 0.077 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr19_-_43969796 0.077 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr14_-_75083313 0.076 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2

CTD-2207P18.2

chr17_+_37856214 0.076 ENST00000445658.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr2_+_66662249 0.076 ENST00000560281.2
MEIS1
Meis homeobox 1
chr19_+_44488330 0.075 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
ZNF155




zinc finger protein 155




chr16_-_28506840 0.075 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.4 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:0086055 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 2.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.5 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.0 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.0 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis