Motif ID: FOXO3_FOXD2

Z-value: 0.670

Transcription factors associated with FOXO3_FOXD2:

Gene SymbolEntrez IDGene Name
FOXD2 ENSG00000186564.5 FOXD2
FOXO3 ENSG00000118689.10 FOXO3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXO3hg19_v2_chr6_+_108881012_1088810380.665.3e-02Click!
FOXD2hg19_v2_chr1_+_47901689_47901689-0.571.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_87804815 4.683 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr7_-_95225768 1.331 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr4_+_172734548 1.051 ENST00000506823.1
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr12_-_71551652 0.987 ENST00000546561.1
TSPAN8
tetraspanin 8
chr20_+_52105495 0.946 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr11_+_117049910 0.870 ENST00000431081.2
ENST00000524842.1
SIDT2

SID1 transmembrane family, member 2

chr1_-_12677714 0.866 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr6_-_64029879 0.833 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr5_+_147258266 0.824 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr5_+_78532003 0.766 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr9_+_137987825 0.764 ENST00000545657.1
OLFM1
olfactomedin 1
chr12_+_106696581 0.755 ENST00000547153.1
ENST00000299045.3
ENST00000546625.1
ENST00000553098.1
TCP11L2



t-complex 11, testis-specific-like 2



chr7_+_106809406 0.745 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr12_-_71148413 0.687 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR


protein tyrosine phosphatase, receptor type, R


chr14_-_21493123 0.637 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chr2_-_183387430 0.623 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_190044480 0.611 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chrX_+_2746850 0.601 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2


glycogenin 2


chr2_+_196521845 0.581 ENST00000359634.5
ENST00000412905.1
SLC39A10

solute carrier family 39 (zinc transporter), member 10

chrX_-_106960285 0.564 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr2_-_71454185 0.562 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr10_-_69597828 0.557 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr11_-_8285405 0.553 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr2_+_36923901 0.552 ENST00000457137.2
VIT
vitrin
chr12_-_71551868 0.545 ENST00000247829.3
TSPAN8
tetraspanin 8
chr4_-_111119804 0.539 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr17_+_57408994 0.522 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr2_+_196521903 0.509 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_20650796 0.508 ENST00000448241.1
AC023137.2
AC023137.2
chr10_+_111985713 0.499 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr2_+_196522032 0.496 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr7_+_114055052 0.482 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr14_-_21493884 0.482 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr12_-_71148357 0.481 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_36923933 0.481 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr14_-_21493649 0.476 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr1_-_45956822 0.475 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr4_-_111120132 0.471 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr1_-_109935819 0.470 ENST00000538502.1
SORT1
sortilin 1
chr12_-_102591604 0.470 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr12_-_91574142 0.467 ENST00000547937.1
DCN
decorin
chr2_+_36923830 0.466 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr2_+_86947296 0.457 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr11_-_102826434 0.455 ENST00000340273.4
ENST00000260302.3
MMP13

matrix metallopeptidase 13 (collagenase 3)

chr1_+_246729724 0.449 ENST00000366513.4
ENST00000366512.3
CNST

consortin, connexin sorting protein

chr1_+_229440129 0.444 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr6_+_72922590 0.429 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_116833500 0.429 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr14_-_74551096 0.428 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr12_-_15038779 0.423 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr3_-_141868357 0.420 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr10_+_114709999 0.413 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr10_+_111985837 0.411 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr17_-_80656528 0.410 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B


RAB40B, member RAS oncogene family


chr5_-_137674000 0.409 ENST00000510119.1
ENST00000513970.1
CDC25C

cell division cycle 25C

chr4_+_183370146 0.408 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr14_-_74551172 0.398 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr3_-_151034734 0.382 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr10_-_69597915 0.375 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr22_-_31688431 0.371 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr8_-_128231299 0.371 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_-_111120334 0.370 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr11_-_115375107 0.368 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr17_+_74261277 0.366 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr8_-_124553437 0.365 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr1_-_16400086 0.364 ENST00000375662.4
FAM131C
family with sequence similarity 131, member C
chr7_+_30174426 0.363 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_12679171 0.359 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr1_-_246729544 0.358 ENST00000544618.1
ENST00000366514.4
TFB2M

transcription factor B2, mitochondrial

chr8_-_134309823 0.357 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr7_+_134464414 0.354 ENST00000361901.2
CALD1
caldesmon 1
chr11_+_33061543 0.354 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr3_-_178865747 0.350 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr16_-_3422283 0.349 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr10_-_69597810 0.345 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr9_-_94124171 0.344 ENST00000422391.2
ENST00000375731.4
ENST00000303617.5
AUH


AU RNA binding protein/enoyl-CoA hydratase


chr6_+_72922505 0.342 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_196440692 0.333 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr1_+_246729815 0.332 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr1_+_104159999 0.331 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr3_-_46608010 0.329 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr1_+_33722080 0.327 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chr12_+_12764773 0.325 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr11_-_66336060 0.324 ENST00000310325.5
CTSF
cathepsin F
chr9_-_3525968 0.322 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr1_+_110527308 0.316 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr3_-_141868293 0.314 ENST00000317104.7
ENST00000494358.1
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr8_-_134309335 0.314 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1









N-myc downstream regulated 1









chr2_-_183387064 0.313 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chrX_-_55208866 0.312 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr11_+_117049445 0.309 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr8_+_52730143 0.306 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr18_-_53303123 0.305 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4


transcription factor 4


chr1_+_227127981 0.303 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr4_-_140223670 0.301 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr3_+_178866199 0.300 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_-_163099546 0.295 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr11_+_10476851 0.293 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr15_-_44828838 0.293 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chrX_+_9431324 0.292 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr11_+_117049854 0.291 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr10_-_99094458 0.289 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr7_+_30174574 0.288 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr10_+_18689637 0.284 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr8_+_26150628 0.284 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr8_-_117886955 0.284 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr6_-_56707943 0.282 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST




dystonin




chr3_+_154801678 0.282 ENST00000462837.1
MME
membrane metallo-endopeptidase
chrX_+_70316005 0.281 ENST00000374259.3
FOXO4
forkhead box O4
chr2_-_163100045 0.279 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr17_-_26694979 0.278 ENST00000438614.1
VTN
vitronectin
chr1_+_92545862 0.276 ENST00000370382.3
ENST00000342818.3
BTBD8

BTB (POZ) domain containing 8

chr10_+_114710211 0.276 ENST00000349937.2
ENST00000369397.4
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr8_-_117886732 0.274 ENST00000517485.1
RAD21
RAD21 homolog (S. pombe)
chr1_-_45956800 0.272 ENST00000538496.1
TESK2
testis-specific kinase 2
chr3_-_178789220 0.271 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr8_-_127570603 0.266 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr3_+_54156664 0.266 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr7_+_30174668 0.266 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr17_-_26695013 0.266 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr20_+_33759854 0.263 ENST00000216968.4
PROCR
protein C receptor, endothelial
chrX_+_2746818 0.263 ENST00000398806.3
GYG2
glycogenin 2
chr6_+_135502501 0.262 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB






v-myb avian myeloblastosis viral oncogene homolog






chr7_+_151791074 0.261 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr4_+_87928140 0.257 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr6_+_134758827 0.256 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr7_+_151791037 0.254 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr16_+_57679859 0.252 ENST00000569494.1
ENST00000566169.1
GPR56

G protein-coupled receptor 56

chr17_-_65241281 0.250 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr17_-_38721711 0.247 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr3_+_187930719 0.246 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_163099885 0.245 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr6_+_62284008 0.243 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr17_-_26697304 0.242 ENST00000536498.1
VTN
vitronectin
chr9_-_128246769 0.239 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr14_-_103987679 0.237 ENST00000553610.1
CKB
creatine kinase, brain
chr2_-_183387283 0.237 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr15_+_101402041 0.234 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1


RP11-66B24.1


chr16_+_57680840 0.234 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56


G protein-coupled receptor 56


chr14_+_32798547 0.234 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr10_-_90751038 0.234 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr6_+_89791507 0.234 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_13299186 0.232 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr2_+_173724771 0.232 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr5_+_40841276 0.231 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr5_+_139505520 0.231 ENST00000333305.3
IGIP
IgA-inducing protein
chr12_-_111926342 0.231 ENST00000389154.3
ATXN2
ataxin 2
chr3_-_157221128 0.228 ENST00000392833.2
ENST00000362010.2
VEPH1

ventricular zone expressed PH domain-containing 1

chr10_-_24911746 0.226 ENST00000320481.6
ARHGAP21
Rho GTPase activating protein 21
chr12_-_31479107 0.225 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr1_-_161337662 0.225 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr9_-_3469181 0.225 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr3_+_54156570 0.224 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr6_-_134639042 0.222 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_772901 0.221 ENST00000305108.4
NINJ2
ninjurin 2
chr2_-_2334888 0.220 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr4_-_174256276 0.220 ENST00000296503.5
HMGB2
high mobility group box 2
chr8_-_117886612 0.220 ENST00000520992.1
RAD21
RAD21 homolog (S. pombe)
chr10_+_123923105 0.218 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_-_241799232 0.217 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr2_-_200335983 0.216 ENST00000457245.1
SATB2
SATB homeobox 2
chr1_+_207277590 0.216 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr8_-_95449155 0.216 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr10_+_114710425 0.215 ENST00000352065.5
ENST00000369395.1
TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

chr6_+_74405501 0.215 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr5_+_32788945 0.214 ENST00000326958.1
AC026703.1
AC026703.1
chr8_-_93978357 0.214 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK





triple QxxK/R motif containing





chr7_+_151791095 0.213 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_+_56367697 0.212 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B





RAB5B, member RAS oncogene family





chr2_+_132479948 0.211 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr1_+_207277632 0.210 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr7_+_134464376 0.210 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr10_+_123923205 0.209 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr6_+_135502408 0.209 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr6_+_74405804 0.207 ENST00000287097.5
CD109
CD109 molecule
chr3_+_54157480 0.207 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr15_-_50411412 0.206 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr16_+_73266661 0.206 ENST00000561802.1
AC140912.1
AC140912.1
chr14_+_102276132 0.206 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr14_-_31926701 0.203 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr12_+_54410664 0.203 ENST00000303406.4
HOXC4
homeobox C4
chr12_-_31479045 0.201 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr5_-_59064458 0.200 ENST00000502575.1
ENST00000507116.1
PDE4D

phosphodiesterase 4D, cAMP-specific

chrX_-_133792480 0.195 ENST00000359237.4
PLAC1
placenta-specific 1
chr10_-_45474237 0.195 ENST00000448778.1
ENST00000298295.3
C10orf10

chromosome 10 open reading frame 10

chr16_-_30107491 0.193 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr8_-_93978333 0.192 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK


triple QxxK/R motif containing


chr1_-_151826173 0.189 ENST00000368817.5
THEM5
thioesterase superfamily member 5
chr2_+_11817713 0.187 ENST00000449576.2
LPIN1
lipin 1
chr1_+_162602244 0.187 ENST00000367922.3
ENST00000367921.3
DDR2

discoidin domain receptor tyrosine kinase 2

chr6_-_30043539 0.187 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr10_-_105421427 0.186 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr5_+_65222500 0.186 ENST00000511297.1
ENST00000506030.1
ERBB2IP

erbb2 interacting protein

chr3_-_57233966 0.185 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr14_+_102276209 0.185 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr17_-_46035187 0.184 ENST00000300557.2
PRR15L
proline rich 15-like
chr11_-_108464321 0.183 ENST00000265843.4
EXPH5
exophilin 5
chr16_+_53469525 0.182 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr3_+_154801312 0.182 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr10_+_123922941 0.181 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 0.8 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.3 0.8 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 0.8 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 1.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 0.8 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.4 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.3 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.6 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 3.4 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.8 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 1.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.1 GO:0044254 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:1903027 regulation of opsonization(GO:1903027)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.8 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 0.1 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.0 0.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.0 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.9 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.3 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.0 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0001768 establishment of T cell polarity(GO:0001768)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.0 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.0 GO:0002276 basophil activation involved in immune response(GO:0002276)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.1 1.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.8 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 4.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.8 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 1.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 1.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.8 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.5 GO:0005179 hormone activity(GO:0005179)
0.0 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 0.2 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade