Motif ID: FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.763


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXP1hg19_v2_chr3_-_71353892_71353928-0.881.8e-03Click!
FOXO6hg19_v2_chr1_+_41827594_418275940.665.2e-02Click!
FOXG1hg19_v2_chr14_+_29236269_29236287,
hg19_v2_chr14_+_29234870_29235050
0.618.0e-02Click!
FOXD1hg19_v2_chr5_-_72744336_727443590.393.0e-01Click!
FOXO1hg19_v2_chr13_-_41240717_412407350.039.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_87804815 4.596 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr11_+_117049910 1.830 ENST00000431081.2
ENST00000524842.1
SIDT2

SID1 transmembrane family, member 2

chr16_-_30107491 1.656 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr10_+_18689637 1.578 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chrX_-_106960285 1.415 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr11_+_117049854 1.272 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr7_+_106809406 1.264 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr4_+_172734548 1.175 ENST00000506823.1
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr17_+_57408994 1.083 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr5_+_78532003 1.053 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr7_+_114055052 0.981 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr12_+_106696581 0.974 ENST00000547153.1
ENST00000299045.3
ENST00000546625.1
ENST00000553098.1
TCP11L2



t-complex 11, testis-specific-like 2



chr14_-_21493123 0.971 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chrX_+_70316005 0.906 ENST00000374259.3
FOXO4
forkhead box O4
chr2_+_196521845 0.895 ENST00000359634.5
ENST00000412905.1
SLC39A10

solute carrier family 39 (zinc transporter), member 10

chr6_-_64029879 0.893 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr17_-_26695013 0.867 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr1_-_12677714 0.860 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr2_+_196521903 0.846 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_-_26694979 0.833 ENST00000438614.1
VTN
vitronectin
chr1_-_161337662 0.826 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr11_+_13299186 0.817 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr2_-_183387430 0.816 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_+_196522032 0.809 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_+_9745786 0.807 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr10_+_111985713 0.795 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr1_+_33722080 0.758 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chr4_-_186696561 0.734 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2





sorbin and SH3 domain containing 2





chr14_-_74551096 0.729 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_+_111985837 0.724 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr11_+_117049445 0.706 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr5_-_95768973 0.683 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr4_-_186696425 0.678 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2


chr6_+_72922590 0.677 ENST00000523963.1
RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_32122106 0.657 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr10_+_99079008 0.654 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chrX_+_135251783 0.646 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr14_-_21493884 0.631 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr2_-_183387064 0.619 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A



phosphodiesterase 1A, calmodulin-dependent



chr7_+_30174426 0.599 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr22_-_31688431 0.589 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr7_-_95225768 0.586 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr12_-_772901 0.574 ENST00000305108.4
NINJ2
ninjurin 2
chr14_-_21493649 0.568 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr2_-_190044480 0.565 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr6_-_30043539 0.561 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr3_-_141868357 0.555 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr1_+_207277632 0.554 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chrX_+_135252050 0.545 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr4_+_183370146 0.542 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr2_-_183387283 0.535 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_-_186733363 0.530 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr17_+_73455788 0.529 ENST00000581519.1
KIAA0195
KIAA0195
chr1_+_161136180 0.527 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX




protoporphyrinogen oxidase




chr6_+_89791507 0.523 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_33168391 0.516 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB


retinoid X receptor, beta


chr4_+_111397216 0.515 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr14_-_74551172 0.508 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_+_23067166 0.494 ENST00000216327.6
ENST00000542041.1
ABHD4

abhydrolase domain containing 4

chr1_+_207277590 0.492 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chrX_-_55208866 0.476 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr12_-_71551652 0.476 ENST00000546561.1
TSPAN8
tetraspanin 8
chr14_+_24583836 0.470 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chr14_+_24584372 0.469 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11




DDB1 and CUL4 associated factor 11




chr9_-_94124171 0.469 ENST00000422391.2
ENST00000375731.4
ENST00000303617.5
AUH


AU RNA binding protein/enoyl-CoA hydratase


chr6_-_134639042 0.468 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_186696515 0.462 ENST00000456596.1
ENST00000414724.1
SORBS2

sorbin and SH3 domain containing 2

chr3_+_113616317 0.460 ENST00000440446.2
ENST00000488680.1
GRAMD1C

GRAM domain containing 1C

chr12_+_12764773 0.459 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr20_+_48909240 0.457 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr17_-_26662464 0.456 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20






intraflagellar transport 20 homolog (Chlamydomonas)






chr12_-_71551868 0.456 ENST00000247829.3
TSPAN8
tetraspanin 8
chr20_+_52105495 0.455 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr6_+_74405501 0.453 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr6_+_72922505 0.449 ENST00000401910.3
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_227127981 0.440 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3


aarF domain containing kinase 3


chr17_+_67410832 0.439 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr19_-_18391708 0.435 ENST00000600972.1
JUND
jun D proto-oncogene
chr2_+_196440692 0.429 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr6_+_74405804 0.423 ENST00000287097.5
CD109
CD109 molecule
chr5_-_16509101 0.422 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr3_+_187930491 0.420 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_+_135251835 0.419 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr2_+_20650796 0.415 ENST00000448241.1
AC023137.2
AC023137.2
chr17_-_1418972 0.411 ENST00000571274.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr2_-_71454185 0.410 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr2_-_163099885 0.408 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr17_-_26662440 0.407 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr4_-_186732892 0.404 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr3_+_178866199 0.404 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr14_+_24584508 0.402 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr3_+_113667354 0.402 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr2_-_163100045 0.402 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr6_+_139094657 0.402 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr8_-_29208183 0.401 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr14_+_23067146 0.400 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr11_-_115375107 0.398 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr3_-_141868293 0.390 ENST00000317104.7
ENST00000494358.1
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chr1_-_12679171 0.385 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr11_-_66336060 0.385 ENST00000310325.5
CTSF
cathepsin F
chr8_+_52730143 0.382 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr5_-_40755987 0.378 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr7_+_30174668 0.377 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_-_163099546 0.376 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr17_-_1508379 0.372 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr7_+_30174574 0.371 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_178790057 0.367 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr14_+_50234827 0.365 ENST00000554589.1
ENST00000557247.1
KLHDC2

kelch domain containing 2

chr9_+_137987825 0.357 ENST00000545657.1
OLFM1
olfactomedin 1
chr19_-_45996465 0.356 ENST00000430715.2
RTN2
reticulon 2
chr10_-_90751038 0.354 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr4_-_186696636 0.345 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr10_-_99094458 0.340 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr12_+_54410664 0.338 ENST00000303406.4
HOXC4
homeobox C4
chr6_+_30853002 0.337 ENST00000421124.2
ENST00000512725.1
DDR1

discoidin domain receptor tyrosine kinase 1

chr14_+_24584056 0.332 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_65373531 0.330 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_-_2334888 0.329 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr8_-_134309335 0.327 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1









N-myc downstream regulated 1









chr1_-_151798546 0.320 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr3_+_187930719 0.313 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr8_+_81397876 0.309 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr12_-_122018114 0.307 ENST00000539394.1
KDM2B
lysine (K)-specific demethylase 2B
chr8_-_134309823 0.307 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr3_-_178865747 0.304 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr5_+_139505520 0.299 ENST00000333305.3
IGIP
IgA-inducing protein
chr1_-_8585945 0.297 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr15_+_96897466 0.297 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3

RP11-522B15.3

chr17_+_48046538 0.294 ENST00000240306.3
DLX4
distal-less homeobox 4
chr19_+_12944722 0.293 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr14_+_75761099 0.292 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5

RP11-293M10.5

chr19_-_47734448 0.291 ENST00000439096.2
BBC3
BCL2 binding component 3
chr1_+_110527308 0.289 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr10_-_105421427 0.287 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr12_+_131438443 0.283 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr6_+_62284008 0.278 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr17_-_39942940 0.277 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr12_-_91574142 0.276 ENST00000547937.1
DCN
decorin
chr21_-_47738112 0.275 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr3_+_54156664 0.274 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr9_+_118916082 0.274 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr4_-_174256276 0.274 ENST00000296503.5
HMGB2
high mobility group box 2
chr1_+_246729724 0.271 ENST00000366513.4
ENST00000366512.3
CNST

consortin, connexin sorting protein

chr4_+_86396265 0.270 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chrX_+_146993534 0.269 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1


fragile X mental retardation 1


chr3_-_178789993 0.267 ENST00000432729.1
ZMAT3
zinc finger, matrin-type 3
chr2_+_86947296 0.267 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr7_-_112579673 0.264 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr15_-_40600111 0.262 ENST00000543785.2
ENST00000260402.3
PLCB2

phospholipase C, beta 2

chr8_-_8318847 0.261 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr17_+_57297807 0.260 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1


glycerophosphodiester phosphodiesterase domain containing 1


chr14_-_76447494 0.259 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr17_+_42248063 0.257 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr11_-_111781554 0.255 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr6_+_125540951 0.253 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr3_-_46608010 0.252 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chrX_+_146993449 0.252 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
FMR1


fragile X mental retardation 1


chrX_+_117629766 0.251 ENST00000276204.6
ENST00000276202.7
DOCK11

dedicator of cytokinesis 11

chr3_+_187930429 0.251 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr17_-_8263538 0.251 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr20_+_10199468 0.250 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr3_+_54157480 0.247 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_+_74261277 0.244 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr4_-_140223614 0.244 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_7580103 0.242 ENST00000596712.1
ZNF358
zinc finger protein 358
chr2_-_157189180 0.242 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr1_+_162602244 0.242 ENST00000367922.3
ENST00000367921.3
DDR2

discoidin domain receptor tyrosine kinase 2

chr1_+_229440129 0.241 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr1_+_9711781 0.240 ENST00000536656.1
ENST00000377346.4
PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

chr12_+_131438496 0.239 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr3_-_3221358 0.237 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN



cereblon



chr17_-_40897043 0.234 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
EZH1









enhancer of zeste homolog 1 (Drosophila)









chr20_+_10199566 0.233 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr2_+_175260451 0.232 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3



secernin 3



chr8_+_101349823 0.232 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr1_+_116654376 0.231 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr1_+_197237352 0.231 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1


crumbs homolog 1 (Drosophila)


chr16_-_86542455 0.230 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR


FOXF1 adjacent non-coding developmental regulatory RNA


chr11_-_111781454 0.229 ENST00000533280.1
CRYAB
crystallin, alpha B
chr1_+_246729815 0.229 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr1_-_45956822 0.227 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr3_+_54156570 0.225 ENST00000415676.2
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr17_+_26662730 0.225 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_160231451 0.224 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr11_-_8285405 0.223 ENST00000335790.3
ENST00000534484.1
LMO1

LIM domain only 1 (rhombotin 1)

chr6_-_136847610 0.223 ENST00000454590.1
ENST00000432797.2
MAP7

microtubule-associated protein 7

chr17_+_58755184 0.222 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr8_-_117886955 0.222 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr18_-_53303123 0.222 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4


transcription factor 4


chr2_+_175260514 0.220 ENST00000424069.1
ENST00000427038.1
SCRN3

secernin 3

chr20_+_62887081 0.218 ENST00000369758.4
ENST00000299468.7
ENST00000609372.1
ENST00000610196.1
ENST00000308824.6
PCMTD2




protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2




chr14_+_32798547 0.218 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr3_-_194030493 0.218 ENST00000456816.1
ENST00000414120.1
ENST00000429578.1
LINC00887


long intergenic non-protein coding RNA 887


chr2_+_173724771 0.216 ENST00000538974.1
ENST00000540783.1
RAPGEF4

Rap guanine nucleotide exchange factor (GEF) 4

chr6_+_136172820 0.215 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr9_-_136933134 0.214 ENST00000303407.7
BRD3
bromodomain containing 3
chr17_+_57642886 0.212 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40




DEAH (Asp-Glu-Ala-His) box polypeptide 40




chr2_-_240230890 0.212 ENST00000446876.1
HDAC4
histone deacetylase 4
chr17_-_8059638 0.212 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr1_-_179851611 0.210 ENST00000610272.1
RP11-533E19.7
RP11-533E19.7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.4 1.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 1.2 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.3 3.8 GO:0033227 dsRNA transport(GO:0033227)
0.2 1.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.7 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.2 1.6 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of high voltage-gated calcium channel activity(GO:1901843) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 1.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 2.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.0 GO:1903027 regulation of opsonization(GO:1903027)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 4.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.3 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 1.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.4 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 1.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.9 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 2.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 1.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.4 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0 1.5 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 1.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.6 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.4 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 1.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.5 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.5 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.0 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.0 0.1 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.7 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0008228 opsonization(GO:0008228)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.7 GO:1902737 dendritic filopodium(GO:1902737)
0.2 0.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.6 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907)
0.1 0.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 2.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 4.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 1.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 1.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 0.9 GO:0002046 opsin binding(GO:0002046)
0.2 1.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 3.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 1.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 3.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 3.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.8 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 3.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.6 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 1.1 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.8 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins