Motif ID: FLI1

Z-value: 0.621


Transcription factors associated with FLI1:

Gene SymbolEntrez IDGene Name
FLI1 ENSG00000151702.12 FLI1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FLI1hg19_v2_chr11_+_128562372_128562397-0.353.6e-01Click!


Activity profile for motif FLI1.

activity profile for motif FLI1


Sorted Z-values histogram for motif FLI1

Sorted Z-values for motif FLI1



Network of associatons between targets according to the STRING database.



First level regulatory network of FLI1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_100842588 1.379 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS











tryptophanyl-tRNA synthetase











chr5_+_35856951 1.202 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R



interleukin 7 receptor



chr1_-_183559693 1.169 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2


neutrophil cytosolic factor 2


chr1_-_183560011 1.067 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr17_+_38673270 0.912 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr17_-_34207295 0.670 ENST00000463941.1
ENST00000293272.3
CCL5

chemokine (C-C motif) ligand 5

chr5_-_138861926 0.616 ENST00000510817.1
TMEM173
transmembrane protein 173
chr8_+_22437664 0.602 ENST00000436754.1
ENST00000426493.1
ENST00000429812.1
PDLIM2


PDZ and LIM domain 2 (mystique)


chr10_+_91061712 0.562 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr5_-_138862326 0.554 ENST00000330794.4
TMEM173
transmembrane protein 173
chr12_+_13061894 0.536 ENST00000540125.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr11_+_2421718 0.485 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
TSSC4




tumor suppressing subtransferable candidate 4




chr14_+_100842735 0.481 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WDR25



WD repeat domain 25



chr1_-_113392399 0.476 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8

RP11-426L16.8

chr4_+_75174180 0.468 ENST00000413830.1
EPGN
epithelial mitogen
chrX_-_70331298 0.445 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG



interleukin 2 receptor, gamma



chr7_-_944631 0.422 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr2_-_75788038 0.402 ENST00000393913.3
ENST00000410113.1
EVA1A

eva-1 homolog A (C. elegans)

chr16_+_56716336 0.390 ENST00000394485.4
ENST00000562939.1
MT1X

metallothionein 1X

chr7_+_100770328 0.387 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr17_-_39928106 0.383 ENST00000540235.1
JUP
junction plakoglobin
chr15_-_71184724 0.355 ENST00000560604.1
THAP10
THAP domain containing 10
chr4_+_75174204 0.351 ENST00000332112.4
ENST00000514968.1
ENST00000503098.1
ENST00000502358.1
ENST00000509145.1
ENST00000505212.1
EPGN





epithelial mitogen





chr1_-_43638168 0.342 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr15_+_59908633 0.341 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_-_6115044 0.315 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr3_-_151034734 0.314 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr9_+_214842 0.311 ENST00000453981.1
ENST00000432829.2
DOCK8

dedicator of cytokinesis 8

chr1_-_162381907 0.293 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr6_+_71104588 0.289 ENST00000418403.1
RP11-462G2.1
RP11-462G2.1
chr8_-_134511587 0.287 ENST00000523855.1
ENST00000523854.1
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr8_-_145013711 0.280 ENST00000345136.3
PLEC
plectin
chr12_-_15114492 0.278 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_+_43104541 0.277 ENST00000372906.2
ENST00000456317.1
TTPAL

tocopherol (alpha) transfer protein-like

chr12_-_15114191 0.274 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_75788424 0.269 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr16_+_27325202 0.269 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R






interleukin 4 receptor






chr2_-_75788428 0.269 ENST00000432649.1
EVA1A
eva-1 homolog A (C. elegans)
chr1_+_156863470 0.260 ENST00000338302.3
ENST00000455314.1
ENST00000292357.7
PEAR1


platelet endothelial aggregation receptor 1


chr5_+_180650271 0.254 ENST00000351937.5
ENST00000315073.5
TRIM41

tripartite motif containing 41

chr17_+_7482785 0.248 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68


CD68 molecule


chr9_-_132404374 0.247 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ASB6


ankyrin repeat and SOCS box containing 6


chr20_+_43104508 0.245 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr9_+_273038 0.244 ENST00000487230.1
ENST00000469391.1
DOCK8

dedicator of cytokinesis 8

chr6_+_126240442 0.244 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7


nuclear receptor coactivator 7


chr9_+_2017063 0.243 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_123691439 0.242 ENST00000540010.1
TRAF1
TNF receptor-associated factor 1
chr19_+_16177826 0.241 ENST00000589897.1
TPM4
tropomyosin 4
chr11_-_118789613 0.237 ENST00000532899.1
BCL9L
B-cell CLL/lymphoma 9-like
chr1_-_150738261 0.235 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr7_-_92465868 0.234 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr11_+_66624527 0.232 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_141075330 0.232 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chr4_+_20702059 0.231 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PACRGL


















PARK2 co-regulated-like


















chr15_-_74284613 0.230 ENST00000316911.6
ENST00000564777.1
ENST00000566081.1
ENST00000316900.5
STOML1



stomatin (EPB72)-like 1



chr12_+_56915713 0.230 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr12_+_56915776 0.230 ENST00000550726.1
ENST00000542360.1
RBMS2

RNA binding motif, single stranded interacting protein 2

chr17_+_4843352 0.229 ENST00000573404.1
ENST00000576452.1
RNF167

ring finger protein 167

chr22_+_50312316 0.227 ENST00000328268.4
CRELD2
cysteine-rich with EGF-like domains 2
chr2_-_68547061 0.227 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr22_+_50312379 0.226 ENST00000407217.3
ENST00000403427.3
CRELD2

cysteine-rich with EGF-like domains 2

chr22_+_50312274 0.226 ENST00000404488.3
CRELD2
cysteine-rich with EGF-like domains 2
chr7_-_75115548 0.224 ENST00000453279.2
POM121C
POM121 transmembrane nucleoporin C
chr15_+_74833518 0.224 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr5_-_131826457 0.223 ENST00000437654.1
ENST00000245414.4
IRF1

interferon regulatory factor 1

chr2_+_28618532 0.216 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr2_+_97203082 0.213 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr5_+_96211643 0.213 ENST00000437043.3
ENST00000510373.1
ERAP2

endoplasmic reticulum aminopeptidase 2

chrX_-_40594755 0.212 ENST00000324817.1
MED14
mediator complex subunit 14
chr14_-_69444957 0.209 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
ACTN1


actinin, alpha 1


chr18_-_52626622 0.208 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr10_+_31610064 0.208 ENST00000446923.2
ENST00000559476.1
ZEB1

zinc finger E-box binding homeobox 1

chr16_-_28937027 0.207 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr4_+_2800722 0.205 ENST00000508385.1
SH3BP2
SH3-domain binding protein 2
chr7_+_37960163 0.202 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr5_-_130970723 0.201 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6





Rap guanine nucleotide exchange factor (GEF) 6





chr17_+_21191341 0.199 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3


mitogen-activated protein kinase kinase 3


chr17_+_16945820 0.198 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr17_-_79533608 0.198 ENST00000572760.1
ENST00000573876.1
NPLOC4

nuclear protein localization 4 homolog (S. cerevisiae)

chr16_-_18887627 0.197 ENST00000563235.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_15469058 0.196 ENST00000432764.2
EAF1
ELL associated factor 1
chr11_+_34645791 0.196 ENST00000529527.1
ENST00000531728.1
ENST00000525253.1
EHF


ets homologous factor


chr2_+_158114051 0.194 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_+_154300217 0.193 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr1_+_183441618 0.193 ENST00000507691.2
ENST00000508461.1
ENST00000419169.1
ENST00000347615.2
ENST00000507469.1
ENST00000515829.2
SMG7





SMG7 nonsense mediated mRNA decay factor





chr12_-_13248598 0.191 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr10_+_69865866 0.191 ENST00000354393.2
MYPN
myopalladin
chr11_+_123325106 0.191 ENST00000525757.1
LINC01059
long intergenic non-protein coding RNA 1059
chr3_-_134093738 0.190 ENST00000506107.1
AMOTL2
angiomotin like 2
chrX_-_153599578 0.190 ENST00000360319.4
ENST00000344736.4
FLNA

filamin A, alpha

chr16_+_3184924 0.189 ENST00000574902.1
ENST00000396878.3
ZNF213

zinc finger protein 213

chrX_-_153718988 0.189 ENST00000263512.4
ENST00000393587.4
ENST00000453912.1
SLC10A3


solute carrier family 10, member 3


chr4_+_20702030 0.189 ENST00000510051.1
ENST00000503585.1
ENST00000360916.5
ENST00000295290.8
ENST00000514485.1
PACRGL




PARK2 co-regulated-like




chr1_+_1260147 0.188 ENST00000343938.4
GLTPD1
glycolipid transfer protein domain containing 1
chr19_+_50431959 0.185 ENST00000595125.1
ATF5
activating transcription factor 5
chr9_-_123691047 0.185 ENST00000373887.3
TRAF1
TNF receptor-associated factor 1
chrX_+_17755696 0.184 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr19_-_1479532 0.183 ENST00000436106.2
C19orf25
chromosome 19 open reading frame 25
chr12_-_133405409 0.182 ENST00000545875.1
ENST00000456883.2
GOLGA3

golgin A3

chr1_+_183441500 0.181 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chr19_-_36822595 0.181 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665


long intergenic non-protein coding RNA 665


chr1_-_43637915 0.179 ENST00000236051.2
EBNA1BP2
EBNA1 binding protein 2
chr8_-_131455835 0.179 ENST00000518721.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_40420802 0.179 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A



major facilitator superfamily domain containing 2A



chr11_+_46722368 0.178 ENST00000311764.2
ZNF408
zinc finger protein 408
chr21_-_35340759 0.178 ENST00000607953.1
AP000569.9
AP000569.9
chr19_-_36822551 0.176 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr1_+_6086354 0.176 ENST00000389632.4
ENST00000428161.1
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr17_+_1944790 0.175 ENST00000575162.1
DPH1
diphthamide biosynthesis 1
chr13_+_111855399 0.175 ENST00000426768.2
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_150480551 0.174 ENST00000369049.4
ENST00000369047.4
ECM1

extracellular matrix protein 1

chr1_-_209792111 0.173 ENST00000455193.1
LAMB3
laminin, beta 3
chr16_+_69599899 0.172 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr12_+_110172572 0.171 ENST00000358906.3
FAM222A
family with sequence similarity 222, member A
chr11_+_72281681 0.170 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr12_+_50690489 0.170 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr11_+_63606373 0.170 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr7_+_150020363 0.170 ENST00000359623.4
ENST00000493307.1
LRRC61

leucine rich repeat containing 61

chr22_+_27068704 0.169 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5


CTA-211A9.5


chr5_-_94417186 0.169 ENST00000312216.8
ENST00000512425.1
MCTP1

multiple C2 domains, transmembrane 1

chr13_+_76362974 0.167 ENST00000497947.2
LMO7
LIM domain 7
chr11_-_64546202 0.167 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1




splicing factor 1




chr8_+_145582217 0.167 ENST00000530047.1
ENST00000527078.1
SLC52A2

solute carrier family 52 (riboflavin transporter), member 2

chr12_-_120663792 0.167 ENST00000546532.1
ENST00000548912.1
PXN

paxillin

chr12_+_76653611 0.167 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr7_+_150020329 0.167 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chrX_-_153718953 0.166 ENST00000369649.4
ENST00000393586.1
SLC10A3

solute carrier family 10, member 3

chr4_+_41983713 0.166 ENST00000333141.5
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr17_+_45973516 0.164 ENST00000376741.4
SP2
Sp2 transcription factor
chr5_-_94417562 0.163 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_+_183441600 0.162 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr16_+_3162557 0.162 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
ZNF205



zinc finger protein 205



chr16_+_4666475 0.162 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr16_-_75285762 0.161 ENST00000564028.1
BCAR1
breast cancer anti-estrogen resistance 1
chr3_-_51975942 0.160 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr8_+_22438009 0.160 ENST00000409417.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr19_+_42387228 0.160 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
ARHGEF1


Rho guanine nucleotide exchange factor (GEF) 1


chr16_+_29832634 0.159 ENST00000565164.1
ENST00000570234.1
MVP

major vault protein

chr5_-_94417314 0.158 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_56485402 0.158 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
OGFOD1



2-oxoglutarate and iron-dependent oxygenase domain containing 1



chr8_+_145582231 0.158 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
SLC52A2




solute carrier family 52 (riboflavin transporter), member 2




chr1_-_157108130 0.157 ENST00000368192.4
ETV3
ets variant 3
chr12_+_48147699 0.157 ENST00000548498.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr2_-_242556900 0.156 ENST00000402545.1
ENST00000402136.1
THAP4

THAP domain containing 4

chrX_+_64808248 0.156 ENST00000609672.1
MSN
moesin
chr8_+_61592073 0.155 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr18_+_61420169 0.155 ENST00000425392.1
ENST00000336429.2
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr1_-_109618566 0.154 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr2_+_135011731 0.154 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr2_-_24583314 0.153 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
ITSN2


intersectin 2


chr7_-_5821225 0.153 ENST00000416985.1
RNF216
ring finger protein 216
chr2_-_69870835 0.153 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr8_+_22437965 0.153 ENST00000409141.1
ENST00000265810.4
PDLIM2

PDZ and LIM domain 2 (mystique)

chr3_+_142720366 0.152 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP



U2 snRNP-associated SURP domain containing



chr19_-_3971050 0.152 ENST00000545797.2
ENST00000596311.1
DAPK3

death-associated protein kinase 3

chr16_-_75285380 0.152 ENST00000393420.6
ENST00000162330.5
BCAR1

breast cancer anti-estrogen resistance 1

chr11_+_67007518 0.151 ENST00000530342.1
ENST00000308783.5
KDM2A

lysine (K)-specific demethylase 2A

chr20_-_1317555 0.151 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr6_-_11382478 0.150 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr22_+_41487711 0.149 ENST00000263253.7
EP300
E1A binding protein p300
chr11_+_63606558 0.148 ENST00000350490.7
ENST00000502399.3
MARK2

MAP/microtubule affinity-regulating kinase 2

chr12_-_72057571 0.148 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr1_-_42384343 0.148 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr15_+_23810903 0.148 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr9_+_116917807 0.147 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr9_-_33473882 0.146 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
NOL6



nucleolar protein 6 (RNA-associated)



chr12_-_1703331 0.146 ENST00000339235.3
FBXL14
F-box and leucine-rich repeat protein 14
chr6_-_42419649 0.146 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr19_-_54567159 0.145 ENST00000338372.2
ENST00000376626.1
VSTM1

V-set and transmembrane domain containing 1

chr10_-_15130767 0.145 ENST00000356189.5
ACBD7
acyl-CoA binding domain containing 7
chr2_+_97202480 0.145 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr6_-_42418999 0.144 ENST00000340840.2
ENST00000354325.2
TRERF1

transcriptional regulating factor 1

chr2_-_220041860 0.143 ENST00000453038.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr11_+_58910295 0.142 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr19_-_54618650 0.142 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chrX_-_102510120 0.142 ENST00000451678.1
TCEAL8
transcription elongation factor A (SII)-like 8
chr19_+_50432400 0.142 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
ATF5


activating transcription factor 5


chr4_-_114900831 0.142 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr1_-_243417762 0.141 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr1_-_157108266 0.141 ENST00000326786.4
ETV3
ets variant 3
chr16_+_69600209 0.141 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_63606477 0.141 ENST00000508192.1
ENST00000361128.5
MARK2

MAP/microtubule affinity-regulating kinase 2

chr19_-_54567035 0.141 ENST00000366170.2
ENST00000425006.2
VSTM1

V-set and transmembrane domain containing 1

chr3_+_47422485 0.140 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23


protein tyrosine phosphatase, non-receptor type 23


chr6_-_28973037 0.140 ENST00000377179.3
ZNF311
zinc finger protein 311
chr11_+_45168182 0.140 ENST00000526442.1
PRDM11
PR domain containing 11
chr7_-_72971934 0.139 ENST00000411832.1
BCL7B
B-cell CLL/lymphoma 7B
chr7_+_102004322 0.139 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr4_-_48082192 0.139 ENST00000507351.1
TXK
TXK tyrosine kinase
chr13_+_111855414 0.139 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_69600058 0.138 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr1_+_162467595 0.138 ENST00000538489.1
ENST00000489294.1
UHMK1

U2AF homology motif (UHM) kinase 1

chr1_+_27248203 0.138 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr16_+_2802316 0.138 ENST00000301740.8
SRRM2
serine/arginine repetitive matrix 2
chr1_+_15480197 0.136 ENST00000400796.3
ENST00000434578.2
ENST00000376008.2
TMEM51


transmembrane protein 51


chrX_-_49041242 0.136 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3



prickle homolog 3 (Drosophila)



chr17_+_75315654 0.136 ENST00000590595.1
SEPT9
septin 9
chr1_+_150480576 0.135 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr22_-_24181174 0.135 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr19_-_6767431 0.135 ENST00000437152.3
ENST00000597687.1
SH2D3A

SH2 domain containing 3A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.7 GO:2000110 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.3 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.3 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 0.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:1990619 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.0 1.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.0 GO:1901654 response to ketone(GO:1901654)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.0 GO:0071506 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506)
0.0 0.1 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.3 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.2 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.3 GO:1990834 response to odorant(GO:1990834)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.2 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.3 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.3 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.0 GO:0060193 positive regulation of lipase activity(GO:0060193)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.0 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.0 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.0 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.0 GO:2000302 synaptic vesicle recycling via endosome(GO:0036466) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.0 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.3 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.0 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 2.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.1 GO:0005135 erythropoietin receptor binding(GO:0005128) interleukin-3 receptor binding(GO:0005135)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0004827 proline-tRNA ligase activity(GO:0004827)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.0 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.9 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.1 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines