Motif ID: EVX2

Z-value: 0.253


Transcription factors associated with EVX2:

Gene SymbolEntrez IDGene Name
EVX2 ENSG00000174279.4 EVX2



Activity profile for motif EVX2.

activity profile for motif EVX2


Sorted Z-values histogram for motif EVX2

Sorted Z-values for motif EVX2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_33709268 0.380 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr15_+_41057818 0.239 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr11_-_115375107 0.150 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr15_-_55563072 0.138 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr15_-_55562582 0.127 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55562451 0.117 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55562479 0.114 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr20_-_50419055 0.108 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr20_-_50418947 0.079 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr1_-_159832438 0.077 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr20_-_50418972 0.071 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr4_+_144354644 0.055 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr1_+_28261492 0.053 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_28261533 0.051 ENST00000411604.1
ENST00000373888.4
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr17_-_9929581 0.042 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr1_+_28261621 0.022 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr4_+_144312659 0.019 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr5_-_96478466 0.014 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr4_-_41884620 0.012 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr17_-_27418537 0.012 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_+_65554493 0.007 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr3_-_48659193 0.005 ENST00000330862.3
TMEM89
transmembrane protein 89
chr12_+_15699286 0.004 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters