Motif ID: EPAS1_BCL3

Z-value: 1.871

Transcription factors associated with EPAS1_BCL3:

Gene SymbolEntrez IDGene Name
BCL3 ENSG00000069399.8 BCL3
EPAS1 ENSG00000116016.9 EPAS1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BCL3hg19_v2_chr19_+_45251804_45251840-0.826.4e-03Click!
EPAS1hg19_v2_chr2_+_46524537_46524553-0.581.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of EPAS1_BCL3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_51588873 7.451 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr20_+_43343517 3.526 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43343476 3.310 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr16_+_57662419 3.289 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56






G protein-coupled receptor 56






chr4_-_186732048 2.990 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr7_+_114055052 2.670 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr20_+_43343886 2.490 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr10_+_111967345 2.473 ENST00000332674.5
ENST00000453116.1
MXI1

MAX interactor 1, dimerization protein

chr16_+_57662596 2.082 ENST00000567397.1
ENST00000568979.1
GPR56

G protein-coupled receptor 56

chr16_+_57662527 2.056 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56




G protein-coupled receptor 56




chr8_+_128426535 2.019 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr8_-_134309335 1.914 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1









N-myc downstream regulated 1









chr9_+_34652164 1.907 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr10_-_62761188 1.842 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr2_+_36923901 1.826 ENST00000457137.2
VIT
vitrin
chr5_-_39425068 1.749 ENST00000515700.1
ENST00000339788.6
DAB2

Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)

chr14_-_92413353 1.704 ENST00000556154.1
FBLN5
fibulin 5
chr4_-_186732892 1.651 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2



sorbin and SH3 domain containing 2



chr2_+_220436917 1.617 ENST00000243786.2
INHA
inhibin, alpha
chr22_+_41956767 1.557 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr5_-_39424961 1.494 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_-_7261772 1.444 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL




complement component 1, r subcomponent-like




chr4_-_185729602 1.390 ENST00000437665.3
ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_+_153651078 1.321 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr19_-_8675559 1.311 ENST00000597188.1
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr11_-_8290263 1.277 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr3_+_52009066 1.265 ENST00000463937.1
ENST00000458031.2
ENST00000273596.3
ABHD14A-ACY1
ACY1
ABHD14A
ABHD14A-ACY1 readthrough (NMD candidate)
aminoacylase 1
abhydrolase domain containing 14A
chr2_+_233243233 1.249 ENST00000392027.2
ALPP
alkaline phosphatase, placental
chrX_+_148793714 1.246 ENST00000355220.5
MAGEA11
melanoma antigen family A, 11
chr20_+_34680698 1.241 ENST00000447825.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_142607740 1.241 ENST00000485766.1
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr3_+_151591422 1.239 ENST00000362032.5
SUCNR1
succinate receptor 1
chr5_+_32711419 1.239 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_-_74022658 1.235 ENST00000427714.2
ENST00000331597.4
P4HA3

prolyl 4-hydroxylase, alpha polypeptide III

chr6_-_166401527 1.231 ENST00000455853.1
ENST00000584911.1
LINC00473

long intergenic non-protein coding RNA 473

chr6_-_166401442 1.196 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr3_-_142608001 1.193 ENST00000295992.3
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr18_+_32290218 1.191 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA


dystrobrevin, alpha


chr19_+_7660716 1.155 ENST00000160298.4
ENST00000446248.2
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr11_+_73675873 1.133 ENST00000537753.1
ENST00000542350.1
DNAJB13

DnaJ (Hsp40) homolog, subfamily B, member 13

chrX_-_15288154 1.117 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9


ankyrin repeat and SOCS box containing 9


chr6_-_16761678 1.115 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr14_+_105190514 1.082 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr2_+_74648848 1.073 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr14_-_48144157 1.061 ENST00000399232.2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr2_-_238499337 1.058 ENST00000411462.1
ENST00000409822.1
RAB17

RAB17, member RAS oncogene family

chr2_+_234294585 1.048 ENST00000447484.1
DGKD
diacylglycerol kinase, delta 130kDa
chr1_+_184356188 1.046 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr1_+_174769006 1.044 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr11_+_7598239 1.037 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_421030 1.035 ENST00000506456.1
AHRR
aryl-hydrocarbon receptor repressor
chr17_-_48207157 1.020 ENST00000330175.4
ENST00000503131.1
SAMD14

sterile alpha motif domain containing 14

chr9_+_2622085 1.018 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr2_+_36923830 1.001 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr12_-_8815404 0.996 ENST00000359478.2
ENST00000396549.2
MFAP5

microfibrillar associated protein 5

chr4_+_183065793 0.979 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chrX_+_135229559 0.944 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr11_-_568369 0.926 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG



MIR210 host gene (non-protein coding)



chr10_+_111985837 0.922 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr3_+_52017454 0.922 ENST00000476854.1
ENST00000476351.1
ENST00000494103.1
ENST00000404366.2
ENST00000469863.1
ACY1




aminoacylase 1




chr14_-_64970494 0.919 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chrX_+_17393543 0.900 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_218843623 0.896 ENST00000413280.1
TNS1
tensin 1
chr12_-_86230315 0.894 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr20_-_50385138 0.893 ENST00000338821.5
ATP9A
ATPase, class II, type 9A
chr11_-_75062730 0.874 ENST00000420843.2
ENST00000360025.3
ARRB1

arrestin, beta 1

chrX_+_135229600 0.871 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr2_+_85646054 0.846 ENST00000389938.2
SH2D6
SH2 domain containing 6
chr11_-_61348292 0.844 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7





synaptotagmin VII





chr8_-_18541603 0.836 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr2_-_238499131 0.826 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr6_-_166401402 0.819 ENST00000581850.1
ENST00000444465.1
LINC00473

long intergenic non-protein coding RNA 473

chr3_-_9291063 0.814 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr20_+_34680620 0.798 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1


erythrocyte membrane protein band 4.1-like 1


chr9_+_101569944 0.786 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr1_+_6845578 0.785 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chr20_+_34680595 0.777 ENST00000406771.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_+_187957646 0.774 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_-_33793430 0.774 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr15_+_43886057 0.768 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B


creatine kinase, mitochondrial 1B


chr2_-_238499303 0.767 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr6_-_136847610 0.760 ENST00000454590.1
ENST00000432797.2
MAP7

microtubule-associated protein 7

chr1_+_6845497 0.750 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr2_+_36923933 0.743 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr9_+_127020202 0.740 ENST00000373600.3
ENST00000320246.5
NEK6

NIMA-related kinase 6

chr4_-_185726906 0.739 ENST00000513317.1
ACSL1
acyl-CoA synthetase long-chain family member 1
chr15_+_43985725 0.738 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr1_+_110453514 0.736 ENST00000369802.3
ENST00000420111.2
CSF1

colony stimulating factor 1 (macrophage)

chr20_-_25843837 0.733 ENST00000376403.1
FAM182B
family with sequence similarity 182, member B
chr1_+_110453462 0.724 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr10_+_71078595 0.723 ENST00000359426.6
HK1
hexokinase 1
chr1_+_61547894 0.709 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_+_241695670 0.707 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_+_4618734 0.703 ENST00000571206.1
ARRB2
arrestin, beta 2
chr11_-_61348576 0.697 ENST00000263846.4
SYT7
synaptotagmin VII
chr22_-_24096562 0.685 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr19_+_11466167 0.677 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr10_-_32217717 0.676 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12



Rho GTPase activating protein 12



chr14_-_48143999 0.674 ENST00000439988.3
MDGA2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr11_-_75062829 0.673 ENST00000393505.4
ARRB1
arrestin, beta 1
chr6_-_136847099 0.665 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr4_-_186732241 0.665 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_151342180 0.665 ENST00000424475.1
SELENBP1
selenium binding protein 1
chr4_-_186733119 0.665 ENST00000419063.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_173420697 0.663 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1


pyruvate dehydrogenase kinase, isozyme 1


chr22_-_24096630 0.652 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr7_-_107642348 0.650 ENST00000393561.1
LAMB1
laminin, beta 1
chr9_+_2621798 0.648 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr3_-_52479043 0.647 ENST00000231721.2
ENST00000475739.1
SEMA3G

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G

chr12_-_71533055 0.646 ENST00000552128.1
TSPAN8
tetraspanin 8
chr11_+_19798964 0.644 ENST00000527559.2
NAV2
neuron navigator 2
chr18_-_21242833 0.644 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr12_+_109535373 0.642 ENST00000242576.2
UNG
uracil-DNA glycosylase
chr13_+_88324870 0.641 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr5_+_169758393 0.640 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3


CTB-114C7.3


chr9_+_127020503 0.635 ENST00000545174.1
ENST00000444973.1
ENST00000454453.1
NEK6


NIMA-related kinase 6


chr4_-_106817137 0.630 ENST00000510876.1
INTS12
integrator complex subunit 12
chr17_-_17942473 0.615 ENST00000585101.1
ENST00000474627.3
ENST00000444058.1
ATPAF2


ATP synthase mitochondrial F1 complex assembly factor 2


chr12_-_2944184 0.609 ENST00000337508.4
NRIP2
nuclear receptor interacting protein 2
chr1_+_44514040 0.608 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4

RP5-1198O20.4

chr11_+_66278080 0.604 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
BBS1





Bardet-Biedl syndrome 1





chr1_+_110453109 0.604 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr5_+_32710736 0.601 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr7_-_95064264 0.597 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2


paraoxonase 2


chr18_+_43914159 0.592 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165


ring finger protein 165


chr16_+_85646891 0.588 ENST00000393243.1
GSE1
Gse1 coiled-coil protein
chr9_+_34653861 0.575 ENST00000556792.1
ENST00000318041.9
ENST00000378817.4
IL11RA


interleukin 11 receptor, alpha


chr9_+_33265011 0.574 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr15_+_66994561 0.574 ENST00000288840.5
SMAD6
SMAD family member 6
chr9_-_33264676 0.573 ENST00000472232.3
ENST00000379704.2
BAG1

BCL2-associated athanogene

chr19_-_9092018 0.570 ENST00000397910.4
MUC16
mucin 16, cell surface associated
chr2_+_20646824 0.566 ENST00000272233.4
RHOB
ras homolog family member B
chr3_-_32022733 0.565 ENST00000438237.2
ENST00000396556.2
OSBPL10

oxysterol binding protein-like 10

chr4_+_140586922 0.564 ENST00000265498.1
ENST00000506797.1
MGST2

microsomal glutathione S-transferase 2

chr3_+_186743261 0.563 ENST00000423451.1
ENST00000446170.1
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr9_-_33264557 0.561 ENST00000473781.1
ENST00000488499.1
BAG1

BCL2-associated athanogene

chr11_+_19799327 0.560 ENST00000540292.1
NAV2
neuron navigator 2
chr17_-_41739283 0.559 ENST00000393661.2
ENST00000318579.4
MEOX1

mesenchyme homeobox 1

chr12_+_107349606 0.549 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
C12orf23


chromosome 12 open reading frame 23


chr1_+_110453608 0.546 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_+_110453203 0.545 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1


colony stimulating factor 1 (macrophage)


chr4_-_152329987 0.543 ENST00000508847.1
RP11-610P16.1
RP11-610P16.1
chr18_-_21242729 0.538 ENST00000585908.2
ANKRD29
ankyrin repeat domain 29
chr12_+_8850277 0.532 ENST00000539923.1
ENST00000537189.1
RIMKLB

ribosomal modification protein rimK-like family member B

chr16_+_57680840 0.520 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56


G protein-coupled receptor 56


chr13_+_88325498 0.520 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr18_+_6729725 0.514 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28


Rho GTPase activating protein 28


chrX_+_135229731 0.513 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr20_+_10199468 0.513 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr5_-_58652788 0.511 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_23751189 0.510 ENST00000374601.3
ENST00000450454.2
TCEA3

transcription elongation factor A (SII), 3

chr19_-_47735918 0.507 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3


BCL2 binding component 3


chr16_+_84328252 0.506 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr14_-_21493884 0.505 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr3_-_169381166 0.501 ENST00000486748.1
MECOM
MDS1 and EVI1 complex locus
chr15_+_96897466 0.498 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3

RP11-522B15.3

chr10_+_18240834 0.495 ENST00000377371.3
ENST00000539911.1
SLC39A12

solute carrier family 39 (zinc transporter), member 12

chr14_-_21493649 0.495 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr10_-_105421427 0.494 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr11_+_66512089 0.492 ENST00000524551.1
ENST00000525908.1
ENST00000360962.4
ENST00000346672.4
ENST00000527634.1
ENST00000540737.1
C11orf80





chromosome 11 open reading frame 80





chr1_-_72748417 0.491 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr20_+_23168759 0.490 ENST00000411595.1
RP4-737E23.2
RP4-737E23.2
chr4_+_53198 0.488 ENST00000509152.2
ENST00000526473.2
ZNF595

zinc finger protein 595

chr8_-_102803163 0.485 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr6_+_143381979 0.484 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1






androgen-induced 1






chr1_+_33722080 0.479 ENST00000483388.1
ENST00000539719.1
ZNF362

zinc finger protein 362

chr8_-_71581377 0.477 ENST00000276590.4
ENST00000522447.1
LACTB2

lactamase, beta 2

chr19_-_6481776 0.471 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C


DENN/MADD domain containing 1C


chr18_+_21464737 0.471 ENST00000586751.1
LAMA3
laminin, alpha 3
chrX_-_134049233 0.469 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr17_-_10017864 0.469 ENST00000323816.4
GAS7
growth arrest-specific 7
chr18_-_48346415 0.469 ENST00000431965.2
ENST00000436348.2
MRO

maestro

chr8_-_128231299 0.466 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr4_+_86748898 0.465 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr15_+_43986069 0.461 ENST00000415044.1
CKMT1A
creatine kinase, mitochondrial 1A
chr8_-_145691031 0.461 ENST00000424149.2
ENST00000530637.1
ENST00000306145.5
CYHR1


cysteine/histidine-rich 1


chr6_-_74230741 0.460 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr6_+_74405501 0.457 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr18_+_21452964 0.453 ENST00000587184.1
LAMA3
laminin, alpha 3
chr12_+_107349497 0.453 ENST00000548125.1
ENST00000280756.4
C12orf23

chromosome 12 open reading frame 23

chr18_+_21452804 0.451 ENST00000269217.6
LAMA3
laminin, alpha 3
chr10_-_62332357 0.447 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_21593972 0.446 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr19_+_19174795 0.446 ENST00000318596.7
SLC25A42
solute carrier family 25, member 42
chr11_+_73676281 0.446 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr15_+_75105170 0.445 ENST00000379709.3
LMAN1L
lectin, mannose-binding, 1 like
chr20_-_43438912 0.444 ENST00000541604.2
ENST00000372851.3
RIMS4

regulating synaptic membrane exocytosis 4

chr19_+_11466062 0.443 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410


Lipid phosphate phosphatase-related protein type 2


chrX_+_52112158 0.440 ENST00000286049.2
XAGE2B
X antigen family, member 2B
chr16_+_89894911 0.439 ENST00000378247.3
ENST00000563972.1
SPIRE2

spire-type actin nucleation factor 2

chr22_-_37545972 0.438 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr4_+_41361616 0.436 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr10_-_62704005 0.435 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr12_+_57522692 0.432 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr9_+_33264861 0.432 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr3_+_49711777 0.430 ENST00000442186.1
ENST00000438011.1
ENST00000457042.1
APEH


acylaminoacyl-peptide hydrolase


chr17_+_68164752 0.429 ENST00000535240.1
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr22_+_24990746 0.427 ENST00000456869.1
ENST00000411974.1
GGT1

gamma-glutamyltransferase 1

chr1_-_72748140 0.425 ENST00000434200.1
NEGR1
neuronal growth regulator 1
chr1_-_111970353 0.425 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0098582 innate vocalization behavior(GO:0098582)
0.6 3.2 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.5 3.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.5 2.7 GO:0002415 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 2.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.5 1.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 1.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 1.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 2.0 GO:0034436 glycoprotein transport(GO:0034436)
0.3 0.3 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 0.3 GO:0006338 chromatin remodeling(GO:0006338)
0.3 2.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.6 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 2.1 GO:0034201 response to oleic acid(GO:0034201)
0.2 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.8 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 0.8 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.6 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.8 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.6 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.6 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.8 GO:0015692 lead ion transport(GO:0015692)
0.1 1.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 5.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 1.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0003357 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.6 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.9 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.5 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.4 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.3 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.5 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.4 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.4 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 1.3 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 3.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.8 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.1 0.9 GO:0000050 urea cycle(GO:0000050)
0.1 0.2 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.7 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.4 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.1 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.1 0.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.4 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.0 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.6 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.2 GO:0021756 striatum development(GO:0021756)
0.1 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 1.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 1.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0003231 cardiac ventricle development(GO:0003231)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 2.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 2.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:1904044 response to aldosterone(GO:1904044)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0072299 visceral serous pericardium development(GO:0061032) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.2 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 2.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0006568 tryptophan metabolic process(GO:0006568)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620) cellular response to topologically incorrect protein(GO:0035967)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 1.4 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 1.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.7 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 1.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0021510 spinal cord development(GO:0021510)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 1.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.4 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:1902474 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) positive regulation of sensory perception of pain(GO:1904058) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.9 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0006473 protein acetylation(GO:0006473)
0.0 0.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.0 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 2.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:0060384 innervation(GO:0060384)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0 0.5 GO:0010573 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of serotonin secretion(GO:0014063) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 1.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.0 GO:1904529 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0051170 nuclear import(GO:0051170)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.1 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 3.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 0.6 GO:0043257 laminin-8 complex(GO:0043257)
0.2 1.0 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.2 2.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 4.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.5 GO:0071953 elastic fiber(GO:0071953)
0.1 1.5 GO:0032009 early phagosome(GO:0032009)
0.1 1.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 2.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 2.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.2 GO:0005915 zonula adherens(GO:0005915)
0.0 1.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 7.1 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 4.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 1.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.0 GO:0043291 RAVE complex(GO:0043291)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.5 2.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.4 3.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4 3.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.4 1.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.3 1.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.7 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.2 0.7 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.2 0.7 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.2 2.2 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.6 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 1.5 GO:0034711 inhibin binding(GO:0034711)
0.2 0.5 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 7.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.4 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 2.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 3.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 3.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0035501 MH1 domain binding(GO:0035501)
0.1 1.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.0 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 0.2 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 4.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 8.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.7 GO:0008430 selenium binding(GO:0008430)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 2.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 3.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0001225 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 2.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 12.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 3.4 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 2.1 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 3.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.5 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.8 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.1 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 0.4 REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 2.1 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.6 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.5 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 2.8 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 5.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.4 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events